6,88096 % | ARK Investment Management LLC | 12 983 002 | 288 777 | 30. 9. 2023 |
6,68024 % | Casdin Capital, LLC | 12 604 275 | -3 430 | 30. 6. 2023 |
5,49467 % | Novartis AG | 10 367 340 | 0 | 10. 4. 2023 |
5,02022 % | BlackRock Institutional Trust Company, N.A. | 9 472 149 | 243 527 | 30. 6. 2023 |
4,63294 % | Nikko Asset Management Co., Ltd. | 8 741 437 | 4 411 248 | 30. 6. 2023 |
4,13788 % | The Vanguard Group, Inc. | 7 807 350 | 102 342 | 30. 6. 2023 |
3,95866 % | Madryn Asset Management, LP | 7 469 202 | 0 | 30. 6. 2023 |
2,76433 % | Tikvah Management LLC | 5 215 740 | 1 001 000 | 30. 6. 2023 |
2,75547 % | Millennium Management LLC | 5 199 020 | -621 917 | 30. 6. 2023 |
2,60043 % | Point72 Asset Management, L.P. | 4 906 490 | 45 427 | 30. 6. 2023 |
1,92241 % | Gold (Larry) | 3 627 197 | -5 505 869 | 31. 12. 2022 |
1,80373 % | Foresite Capital Management, LLC | 3 403 276 | -113 196 | 30. 6. 2023 |
1,65982 % | Geode Capital Management, L.L.C. | 3 131 743 | 107 899 | 30. 6. 2023 |
1,56473 % | State Street Global Advisors (US) | 2 952 331 | 40 876 | 30. 6. 2023 |
1,35664 % | Marshall Wace LLP | 2 559 708 | 0 | 30. 6. 2023 |
1,35053 % | Barclays Bank PLC | 2 548 174 | -20 928 | 30. 6. 2023 |
1,16562 % | Magnetar Capital Partners LP | 2 199 292 | -100 725 | 30. 6. 2023 |
0,99154 % | Redmile Group, LLC | 1 870 839 | 0 | 30. 6. 2023 |
0,89917 % | Nan Fung Group Holdings Ltd | 1 696 558 | 0 | 30. 6. 2023 |
0,79500 % | Perceptive Advisors LLC | 1 500 000 | 0 | 30. 6. 2023 |
0,70691 % | Morgan Stanley Investment Management Inc. (US) | 1 333 804 | 151 807 | 30. 6. 2023 |
0,63684 % | Northern Trust Investments, Inc. | 1 201 587 | 1 406 | 30. 6. 2023 |
0,61514 % | Charles Schwab Investment Management, Inc. | 1 160 653 | 33 947 | 30. 6. 2023 |
0,52176 % | Nikko Asset Management Americas, Inc. | 984 457 | 273 530 | 31. 12. 2022 |
0,46015 % | Zweig-DiMenna Associates, Inc. | 868 218 | -400 000 | 30. 6. 2023 |
0,42683 % | Gagnon Securities LLC | 805 337 | -26 764 | 30. 6. 2023 |
0,42388 % | Monashee Investment Management, LLC | 799 784 | -190 077 | 30. 6. 2023 |
0,41096 % | BlackRock Financial Management, Inc. | 775 403 | -9 176 | 30. 6. 2023 |
0,39994 % | Goldman Sachs & Company, Inc. | 754 599 | 137 291 | 30. 6. 2023 |
0,32728 % | Dimensional Fund Advisors, L.P. | 617 509 | 537 524 | 30. 6. 2023 |
0,32100 % | Gagnon Advisors, LLC | 605 671 | 92 703 | 30. 6. 2023 |
0,24796 % | Driehaus Capital Management, LLC | 467 856 | 0 | 30. 6. 2023 |
0,24192 % | Voya Investments, LLC | 456 455 | 0 | 30. 4. 2023 |
0,23850 % | General American Investors Company, Inc. | 450 000 | 0 | 30. 6. 2023 |
0,23210 % | Parametric Portfolio Associates LLC | 437 917 | 8 577 | 30. 6. 2023 |
0,23197 % | Saba Capital Management, L.P. | 437 676 | -18 779 | 30. 6. 2023 |
0,23193 % | BlackRock Investment Management, LLC | 437 611 | 24 438 | 30. 6. 2023 |
0,22525 % | Quake (Stephen Ph.D.) | 425 000 | 0 | 10. 4. 2023 |
0,22069 % | BofA Global Research (US) | 416 401 | -78 695 | 30. 6. 2023 |
0,21975 % | Nuveen LLC | 414 633 | 0 | 30. 6. 2023 |
0,21200 % | RBF Capital, LLC | 400 000 | -116 018 | 30. 6. 2023 |
0,21018 % | Lillis (Charles M) | 396 576 | 3 430 | 10. 4. 2023 |
0,20901 % | BNY Mellon Asset Management | 394 351 | -9 461 | 30. 6. 2023 |
0,18428 % | Schweizerische Nationalbank | 347 700 | 44 200 | 30. 6. 2023 |
0,17225 % | Intellectus Partners, LLC | 325 000 | 0 | 30. 6. 2023 |
0,14896 % | Johnson & Johnson Innovation-JJDC, Inc. | 281 052 | 0 | 30. 6. 2023 |
0,14491 % | Boothbay Fund Management, LLC | 273 422 | -11 741 | 30. 6. 2023 |
0,13193 % | Northern Trust Global Investments | 248 927 | 132 684 | 30. 6. 2023 |
0,13103 % | Cowen & Co., LLC | 247 226 | 0 | 30. 6. 2023 |
0,12257 % | Rhumbline Advisers Ltd. Partnership | 231 258 | -7 027 | 30. 6. 2023 |
0,11295 % | JP Morgan Asset Management | 213 109 | 18 252 | 30. 6. 2023 |
0,10240 % | Morgan Stanley & Co. LLC | 193 203 | -4 078 | 30. 6. 2023 |
0,10140 % | AllianceBernstein L.P. | 191 320 | 32 820 | 30. 6. 2023 |
0,10110 % | California State Teachers Retirement System | 190 758 | 9 942 | 30. 6. 2023 |
0,09727 % | Connor, Clark & Lunn Investment Management Ltd. | 183 520 | -128 143 | 30. 6. 2023 |
0,09156 % | BlackRock Investment Management (UK) Ltd. | 172 756 | 0 | 30. 6. 2023 |
0,09100 % | UBS Asset Management (Switzerland) | 171 701 | 0 | 31. 3. 2023 |
0,09013 % | Invesco Capital Management LLC | 170 048 | -1 819 | 30. 6. 2023 |
0,07065 % | Oak Family Advisors, LLC | 133 296 | -21 033 | 30. 9. 2023 |
0,06890 % | Kent Lake Capital LLC | 129 995 | 129 995 | 30. 6. 2023 |
0,06690 % | Mellon Investments Corporation | 126 235 | -16 638 | 30. 6. 2023 |
0,06514 % | Legal & General Investment Management Ltd. | 122 907 | 67 185 | 30. 6. 2023 |
0,06230 % | UBS Financial Services, Inc. | 117 546 | 45 899 | 30. 6. 2023 |
0,06002 % | D. E. Shaw & Co., L.P. | 113 248 | -93 859 | 30. 6. 2023 |
0,05981 % | Credit Suisse Funds AG | 112 857 | 8 333 | 30. 6. 2023 |
0,05830 % | Tamarack Advisers, LP | 110 000 | -365 000 | 30. 6. 2023 |
0,05326 % | Commonwealth Financial Network | 100 500 | 500 | 30. 6. 2023 |
0,05300 % | Edgewood Management LLC | 100 000 | 0 | 30. 6. 2023 |
0,05164 % | Post (Richard A) | 97 430 | 40 000 | 10. 4. 2023 |
0,05074 % | Susquehanna International Group, LLP | 95 727 | -34 672 | 30. 6. 2023 |
0,04874 % | Inspire Advisors, LLC | 91 969 | 91 969 | 30. 6. 2023 |
0,04823 % | Abaris Investment Management AG | 91 000 | -60 000 | 30. 4. 2023 |
0,04800 % | Towercrest Capital Management, LLC | 90 575 | 90 575 | 30. 6. 2023 |
0,04606 % | BlackRock Advisors (UK) Limited | 86 907 | -259 | 30. 9. 2023 |
0,04573 % | Avantis Investors | 86 292 | 32 909 | 30. 9. 2023 |
0,04416 % | MetLife Investment Management, LLC | 83 329 | 0 | 30. 6. 2023 |
0,04202 % | T. Rowe Price International Ltd | 79 285 | 1 362 | 30. 6. 2023 |
0,04157 % | Cox (Troy M) | 78 430 | -25 070 | 10. 4. 2023 |
0,04135 % | DWS Investments UK Limited | 78 019 | -19 290 | 30. 6. 2023 |
0,04065 % | Jump Financial, LLC | 76 690 | 76 690 | 30. 6. 2023 |
0,04026 % | American Century Investment Management, Inc. | 75 956 | 42 025 | 30. 6. 2023 |
0,03885 % | Goldman Sachs Asset Management, L.P. | 73 296 | -15 036 | 30. 6. 2023 |
0,03856 % | SunAmerica Asset Management, LLC | 72 749 | -1 584 | 30. 6. 2023 |
0,03668 % | SG Americas Securities, L.L.C. | 69 212 | 55 626 | 30. 9. 2023 |
0,03640 % | Citadel Advisors LLC | 68 673 | -57 560 | 30. 6. 2023 |
0,03567 % | BlackRock Asset Management Ireland Limited | 67 311 | 4 604 | 30. 6. 2023 |
0,03445 % | Lauxera Capital Partners | 65 000 | 0 | 31. 8. 2023 |
0,03444 % | Hightower Advisors, LLC | 64 984 | 1 482 | 30. 6. 2023 |
0,03443 % | Manulife Investment Management (North America) Limited | 64 962 | 4 117 | 30. 6. 2023 |
0,03419 % | Janus Henderson Investors | 64 509 | -1 673 305 | 30. 6. 2023 |
0,03392 % | Caspar Asset Management S.A. | 64 000 | 9 000 | 31. 12. 2022 |
0,03392 % | Vaughan Nelson Investment Management, L.P. | 63 998 | 22 936 | 30. 6. 2023 |
0,03345 % | Public Employees' Retirement Association of CO | 63 118 | 0 | 30. 6. 2023 |
0,03322 % | Emerge Canada Inc | 62 683 | 0 | 31. 8. 2023 |
0,03178 % | Voya Investment Management LLC | 59 960 | 4 481 | 30. 6. 2023 |
0,03163 % | Dimensional Fund Advisors, Ltd. | 59 681 | 0 | 31. 8. 2023 |
0,03152 % | Royce Investment Partners | 59 470 | 6 370 | 30. 6. 2023 |
0,03053 % | Wells Fargo Bank, N.A. | 57 606 | 29 922 | 30. 6. 2023 |
0,02915 % | Corient Private Wealth LLC | 55 000 | 55 000 | 30. 6. 2023 |
0,02688 % | Rice Hall James & Associates, LLC | 50 714 | -1 516 | 31. 1. 2022 |