12,75941 % | Pontifax Venture Capital | 4 787 331 | 0 | 31. 3. 2024 |
10,65957 % | Fidelity Management & Research Company LLC | 3 999 471 | -361 597 | 30. 6. 2024 |
5,73238 % | BlackRock Institutional Trust Company, N.A. | 2 150 789 | 284 388 | 30. 6. 2024 |
4,66889 % | The Vanguard Group, Inc. | 1 751 767 | 211 362 | 30. 6. 2024 |
4,06690 % | Darwin Global Management Ltd | 1 525 902 | 89 952 | 30. 6. 2024 |
3,65425 % | Arkin Bio Ventures LP | 1 371 074 | -441 241 | 26. 1. 2023 |
3,55526 % | Alkeon Capital Management LLC | 1 333 934 | 0 | 30. 6. 2024 |
3,25527 % | State Street Global Advisors (US) | 1 221 376 | -341 519 | 30. 6. 2024 |
3,11652 % | T. Rowe Price Associates, Inc. | 1 169 320 | -32 654 | 30. 6. 2024 |
2,71518 % | OrbiMed Advisors, LLC | 1 018 734 | -250 000 | 13. 8. 2024 |
2,61783 % | Braidwell LP | 982 209 | 244 830 | 30. 6. 2024 |
2,39626 % | Jefferies LLC | 899 077 | 265 406 | 30. 6. 2024 |
2,34367 % | TCG Crossover Management, LLC | 879 344 | 0 | 30. 6. 2024 |
2,06782 % | Woodline Partners LP | 775 845 | 14 145 | 30. 6. 2024 |
1,91975 % | Fidelity Institutional Asset Management | 720 289 | 62 841 | 30. 6. 2024 |
1,83456 % | Holocene Advisors, LP | 688 326 | 50 343 | 30. 6. 2024 |
1,81125 % | Geode Capital Management, L.L.C. | 679 580 | 83 734 | 30. 6. 2024 |
1,53065 % | Partners Innovation Fund LLC | 574 301 | -1 191 | 31. 3. 2024 |
1,47256 % | Redmile Group, LLC | 552 506 | 0 | 30. 6. 2024 |
1,46300 % | Adar1 Capital Management LLC | 548 916 | 210 673 | 30. 6. 2024 |
1,33051 % | Eventide Asset Management, LLC | 499 208 | -180 792 | 30. 6. 2024 |
1,32568 % | Candriam Luxembourg S.A. | 497 396 | 0 | 30. 9. 2024 |
1,26740 % | Goldman Sachs & Company, Inc. | 475 529 | 271 338 | 30. 6. 2024 |
1,17765 % | Candriam Belgium S.A. | 441 855 | -210 144 | 30. 6. 2024 |
1,09404 % | Citadel Advisors LLC | 410 484 | -39 794 | 30. 6. 2024 |
1,08644 % | Cowen Investment Management LLC | 407 633 | 5 515 | 30. 9. 2023 |
1,04732 % | Millennium Management LLC | 392 956 | 55 293 | 30. 6. 2024 |
1,03412 % | Franklin Advisers, Inc. | 388 000 | -231 609 | 30. 6. 2024 |
1,00961 % | Nantahala Capital Management, LLC | 378 807 | 84 810 | 30. 6. 2024 |
0,98707 % | Point72 Asset Management, L.P. | 370 350 | -601 531 | 30. 6. 2024 |
0,97948 % | Opaleye Management Inc. | 367 500 | 0 | 30. 6. 2024 |
0,91471 % | Avidity Partners Management LP | 343 200 | 133 500 | 30. 6. 2024 |
0,87777 % | Morgan Stanley & Co. LLC | 329 338 | 48 742 | 30. 6. 2024 |
0,79470 % | American Century Investment Management, Inc. | 298 170 | 59 364 | 30. 6. 2024 |
0,71471 % | Emerald Advisers LLC | 268 158 | 268 158 | 30. 9. 2024 |
0,70622 % | Oppenheimer Asset Management Inc. | 264 973 | 0 | 30. 6. 2024 |
0,67392 % | Seehra (Jasbir) | 252 856 | 0 | 31. 3. 2024 |
0,61301 % | Adage Capital Management, L.P. | 230 000 | 40 000 | 30. 6. 2024 |
0,60668 % | Charles Schwab Investment Management, Inc. | 227 628 | 19 870 | 30. 6. 2024 |
0,59623 % | Assenagon Asset Management S.A. | 223 704 | 199 245 | 30. 9. 2024 |
0,59062 % | Soleus Capital Management, L.P. | 221 600 | -52 000 | 30. 6. 2024 |
0,57254 % | Northern Trust Investments, Inc. | 214 817 | -220 | 30. 6. 2024 |
0,52939 % | Parkman Healthcare Partners LLC | 198 627 | 20 292 | 30. 6. 2024 |
0,49973 % | EcoR1 Capital, LLC | 187 500 | 0 | 30. 6. 2024 |
0,46854 % | BofA Global Research (US) | 175 796 | 6 151 | 30. 6. 2024 |
0,46827 % | D. E. Shaw & Co., L.P. | 175 695 | 156 821 | 30. 6. 2024 |
0,46280 % | BlackRock Financial Management, Inc. | 173 644 | 27 865 | 30. 6. 2024 |
0,43101 % | Dimensional Fund Advisors, L.P. | 161 715 | -3 691 | 30. 6. 2024 |
0,42013 % | Blue Owl Capital Holdings LP | 157 633 | -15 000 | 30. 6. 2024 |
0,40102 % | AllianceBernstein L.P. | 150 462 | 58 604 | 30. 6. 2024 |
0,38640 % | Granahan Investment Management, LLC | 144 976 | -4 037 | 30. 6. 2024 |
0,32899 % | DWS Investments UK Limited | 123 438 | 587 | 30. 6. 2024 |
0,31062 % | WCM Investment Management | 116 544 | -486 | 30. 6. 2024 |
0,30337 % | Readystate Asset Management LP | 113 823 | 19 450 | 30. 6. 2024 |
0,28404 % | Nuveen LLC | 106 572 | 6 541 | 30. 6. 2024 |
0,23624 % | Balyasny Asset Management LP | 88 636 | 63 124 | 30. 6. 2024 |
0,22655 % | Integral Health Asset Management, LLC | 85 000 | 45 000 | 30. 6. 2024 |
0,21949 % | Russell Investments Trust Company | 82 352 | 0 | 30. 6. 2024 |
0,20277 % | BNY Mellon Asset Management | 76 081 | 11 393 | 30. 6. 2024 |
0,19800 % | Superstring Capital Management LP | 74 288 | 40 460 | 30. 6. 2024 |
0,19462 % | BlackRock Investment Management, LLC | 73 021 | 13 695 | 30. 6. 2024 |
0,19120 % | Ensign Peak Advisors, Inc. | 71 740 | 0 | 30. 6. 2024 |
0,19083 % | BlackRock Asset Management Ireland Limited | 71 601 | 19 391 | 30. 6. 2024 |
0,18469 % | BlackRock Advisors (UK) Limited | 69 294 | 1 387 | 30. 9. 2024 |
0,18058 % | Dafna Capital Management, LLC | 67 754 | 0 | 30. 6. 2024 |
0,17472 % | UBS Financial Services, Inc. | 65 555 | -58 630 | 30. 6. 2024 |
0,15340 % | Rafferty Asset Management LLC | 57 555 | -61 956 | 30. 6. 2024 |
0,15139 % | Schweizerische Nationalbank | 56 800 | 6 900 | 30. 6. 2024 |
0,15019 % | Allianz Global Investors GmbH | 56 350 | 0 | 31. 8. 2024 |
0,14951 % | Voya Investment Management LLC | 56 097 | -3 176 | 30. 6. 2024 |
0,14413 % | Two Sigma Investments, LP | 54 079 | 14 957 | 30. 6. 2024 |
0,13058 % | Fred Alger Management, LLC | 48 993 | -16 887 | 30. 6. 2024 |
0,13057 % | TwinBeech Capital LP | 48 988 | 48 988 | 30. 6. 2024 |
0,12741 % | Engineers Gate Manager, L.P. | 47 806 | 15 347 | 30. 6. 2024 |
0,12238 % | Goldman Sachs Asset Management, L.P. | 45 918 | -8 259 | 30. 6. 2024 |
0,11966 % | Jane Street Capital, L.L.C. | 44 897 | 25 518 | 30. 6. 2024 |
0,11098 % | Rhumbline Advisers Ltd. Partnership | 41 638 | 7 111 | 30. 6. 2024 |
0,10450 % | HighVista Strategies LLC | 39 208 | 0 | 30. 6. 2024 |
0,10144 % | Y-Intercept (Hong Kong) Ltd | 38 061 | 38 061 | 30. 6. 2024 |
0,09171 % | Mellon Investments Corporation | 34 409 | 7 378 | 30. 6. 2024 |
0,09092 % | Schonfeld Strategic Advisors LLC | 34 113 | -26 292 | 30. 6. 2024 |
0,08890 % | PFM Health Sciences, LP | 33 355 | 33 355 | 30. 6. 2024 |
0,08881 % | Polen Capital Management, LLC | 33 321 | 0 | 31. 8. 2024 |
0,08483 % | Legal & General Investment Management Ltd. | 31 827 | 6 372 | 30. 6. 2024 |
0,08464 % | State of Wisconsin Investment Board | 31 758 | 12 827 | 30. 6. 2024 |
0,08325 % | Qube Research & Technologies Ltd | 31 235 | 28 973 | 30. 6. 2024 |
0,08023 % | J. Goldman & Co., L.P. | 30 102 | 30 102 | 30. 6. 2024 |
0,08006 % | Hudson Bay Capital Management LP | 30 038 | -35 400 | 30. 6. 2024 |
0,07530 % | California State Teachers Retirement System | 28 252 | 2 938 | 30. 6. 2024 |
0,07501 % | Alps Advisors, Inc. | 28 144 | 2 766 | 30. 6. 2024 |
0,06604 % | Barclays Bank PLC | 24 780 | -4 531 | 30. 6. 2024 |
0,06482 % | UBS Fund Management (Switzerland) AG | 24 320 | -9 842 | 30. 6. 2024 |
0,06371 % | BlackRock Investment Management (UK) Ltd. | 23 903 | 68 | 30. 6. 2024 |
0,05984 % | UBS O'Connor LLC | 22 453 | 5 400 | 30. 6. 2024 |
0,05964 % | Marshall Wace LLP | 22 377 | -250 594 | 30. 6. 2024 |
0,05838 % | NEOS Investment Management, LLC | 21 904 | 7 640 | 30. 6. 2024 |
0,05560 % | BIT Capital GmbH | 20 862 | 20 862 | 31. 12. 2023 |
0,05517 % | Erste Asset Management GmbH | 20 700 | 0 | 31. 7. 2024 |
0,05409 % | Platinum Asset Management | 20 293 | -14 422 | 30. 6. 2024 |
0,05330 % | Artia Global Partners LP | 20 000 | 20 000 | 30. 6. 2024 |