6,71405 % | Opaleye Management Inc. | 2 304 262 | -274 647 | 30. 6. 2024 |
5,53613 % | RA Capital Management, LP | 1 900 000 | 0 | 30. 6. 2024 |
2,86746 % | StemPoint Capital LP | 984 113 | 815 671 | 30. 6. 2024 |
2,41318 % | Shefferman (Jesse M) | 828 203 | -8 563 | 28. 8. 2024 |
2,36488 % | Boxer Capital, L.L.C. | 811 627 | 602 400 | 30. 6. 2024 |
1,93873 % | Citadel Advisors LLC | 665 372 | 52 240 | 30. 6. 2024 |
1,56420 % | Baker Bros. Advisors LP | 536 832 | 337 161 | 30. 6. 2024 |
1,51515 % | Armistice Capital LLC | 520 000 | -580 000 | 30. 6. 2024 |
1,39860 % | Velan Capital Investment Management LP | 480 000 | 480 000 | 30. 6. 2024 |
1,24596 % | The Vanguard Group, Inc. | 427 612 | 0 | 30. 6. 2024 |
0,88213 % | Heights Capital Management, Inc. | 302 746 | -297 634 | 30. 6. 2024 |
0,68849 % | Two Sigma Investments, LP | 236 291 | 172 132 | 30. 6. 2024 |
0,57692 % | Beshar (Luke M) | 198 000 | 0 | 11. 4. 2024 |
0,52655 % | Ikarian Capital LLC | 180 712 | -21 989 | 30. 6. 2024 |
0,43823 % | Renaissance Technologies LLC | 150 400 | 65 800 | 30. 6. 2024 |
0,40946 % | Geode Capital Management, L.L.C. | 140 526 | 57 619 | 30. 6. 2024 |
0,37057 % | Oppenheimer Asset Management Inc. | 127 181 | 117 181 | 30. 6. 2024 |
0,36422 % | ACCI Capital Investments SGIIC, SA | 125 000 | 40 000 | 31. 7. 2024 |
0,33423 % | Privium Fund Management (UK) Ltd | 114 708 | -5 022 | 30. 6. 2024 |
0,32469 % | BlackRock Institutional Trust Company, N.A. | 111 434 | 82 884 | 30. 6. 2024 |
0,29138 % | Woodline Partners LP | 100 001 | 100 001 | 30. 6. 2024 |
0,22538 % | Marshall Wace LLP | 77 351 | 77 351 | 30. 6. 2024 |
0,18453 % | Zummo (Jacqueline) | 63 331 | -291 | 11. 4. 2024 |
0,14860 % | Abaris Investment Management AG | 51 000 | 25 500 | 31. 12. 2023 |
0,12821 % | LPL Financial LLC | 44 000 | 16 000 | 30. 6. 2024 |
0,10781 % | CIBC World Markets Inc. | 37 000 | 37 000 | 30. 6. 2024 |
0,09615 % | Garceau (Roger J) | 33 000 | 0 | 11. 4. 2024 |
0,09033 % | Levy (Richard S) | 31 000 | 0 | 11. 4. 2024 |
0,09033 % | Sargen (Gregory P) | 31 000 | 0 | 11. 4. 2024 |
0,08693 % | Fry (Hannah) | 29 836 | 6 772 | 19. 1. 2024 |
0,08443 % | Northern Trust Investments, Inc. | 28 976 | 11 385 | 30. 6. 2024 |
0,07751 % | State Street Global Advisors (US) | 26 600 | 0 | 30. 6. 2024 |
0,07721 % | Solomon (Michael Edward) | 26 500 | 0 | 11. 4. 2024 |
0,07051 % | Bridgeway Capital Management, LLC | 24 200 | -34 800 | 30. 6. 2024 |
0,06776 % | Bandari (Jathin) | 23 255 | 18 244 | 19. 1. 2024 |
0,05883 % | Boothbay Fund Management, LLC | 20 191 | -2 456 | 30. 6. 2024 |
0,05828 % | Truist Bank | 20 000 | 0 | 30. 6. 2024 |
0,05661 % | Commonwealth Financial Network | 19 428 | 0 | 30. 9. 2024 |
0,04161 % | Newton Investment Management North America, LLC | 14 280 | 0 | 30. 6. 2024 |
0,03744 % | Jane Street Capital, L.L.C. | 12 850 | 12 850 | 30. 6. 2024 |
0,02924 % | Susquehanna International Group, LLP | 10 036 | -1 149 | 30. 6. 2024 |
0,01894 % | Gesiuris Asset Management S.G.I.I.C., S.A. | 6 500 | 0 | 31. 8. 2023 |
0,01171 % | Tower Research Capital LLC | 4 019 | 1 439 | 30. 6. 2024 |
0,01119 % | BlackRock Investment Management, LLC | 3 839 | 2 585 | 30. 6. 2024 |
0,01057 % | BNY Mellon Asset Management | 3 627 | 0 | 30. 6. 2024 |
0,01020 % | RBC Dominion Securities, Inc. | 3 500 | 0 | 30. 6. 2024 |
0,00816 % | RBC Capital Partners | 2 802 | 2 316 | 30. 6. 2024 |
0,00743 % | Group One Trading, L.P. | 2 550 | 2 550 | 30. 6. 2024 |
0,00646 % | Dimensional Fund Advisors, Ltd. | 2 216 | 0 | 30. 9. 2024 |
0,00260 % | Blackstone Alternative Investment Advisors LLC | 894 | 494 | 30. 6. 2024 |
0,00146 % | Wells Fargo Advisors | 500 | 0 | 30. 6. 2024 |
0,00043 % | BofA Global Research (US) | 149 | 149 | 30. 6. 2024 |
0,00029 % | Osaic Holdings, Inc. | 100 | 0 | 30. 6. 2024 |
0,00001 % | Qube Research & Technologies Ltd | 2 | 0 | 30. 6. 2024 |
0 % | Fabbio (Patrick) | 0 | -22 000 | 11. 4. 2024 |
0 % | Simplex Trading, LLC | 0 | -17 850 | 30. 6. 2024 |
0 % | Morgan Stanley Smith Barney LLC | 0 | -25 | 30. 6. 2023 |
0 % | Assenagon Asset Management S.A. | 0 | -15 831 | 31. 3. 2024 |
0 % | Perceptive Advisors LLC | 0 | -290 051 | 30. 6. 2023 |
0 % | Apo Asset Management GmbH | 0 | -7 535 | 30. 4. 2023 |
0 % | Medical Strategy GmbH | 0 | -56 153 | 30. 9. 2023 |
0 % | Millennium Management LLC | 0 | -11 506 | 31. 3. 2024 |
0 % | OrbiMed Advisors, LLC | 0 | -772 584 | 31. 12. 2023 |
0 % | Federated MDTA LLC | 0 | -124 | 31. 3. 2023 |
0 % | Acadian Asset Management LLC | 0 | -6 314 | 30. 6. 2024 |
0 % | Wells Fargo Bank, N.A. | 0 | -70 | 30. 6. 2024 |
0 % | BlackRock Financial Management, Inc. | 0 | -1 060 | 30. 6. 2024 |
0 % | Morgan Stanley & Co. LLC | 0 | -58 339 | 30. 6. 2023 |
0 % | Manulife Investment Management (North America) Limited | 0 | -372 | 31. 5. 2023 |
0 % | Fidelity Management & Research Company LLC | 0 | -9 | 30. 9. 2023 |
0 % | Dimensional Fund Advisors, L.P. | 0 | -12 126 | 30. 6. 2024 |
0 % | J.P. Morgan Securities LLC | 0 | -22 | 30. 6. 2024 |
0 % | UBS Financial Services, Inc. | 0 | -3 725 | 30. 6. 2024 |
0 % | Adar1 Capital Management LLC | 0 | -2 000 | 30. 6. 2024 |