7,05 % | Commodore Capital LP | 4 747 373 | 319 301 | 31.12.2023 |
5,94 % | Incyte Corp | 4 004 544 | 0 | 25.03.2024 |
5,07 % | Samlyn Capital, LLC | 3 412 410 | 155 892 | 31.12.2023 |
4,48 % | Deerfield Management Company, L.P. | 3 019 901 | -857 037 | 31.12.2023 |
4,09 % | BVF Partners L.P. | 2 752 420 | 0 | 31.12.2023 |
3,52 % | RTW Investments L.P. | 2 373 625 | 376 861 | 31.12.2023 |
3,41 % | Federated Hermes Global Investment Management Corp. | 2 297 700 | -1 339 609 | 29.02.2024 |
3,19 % | VR Adviser, LLC | 2 148 214 | 422 000 | 31.12.2023 |
2,98 % | Wellington Management Company, LLP | 2 009 403 | -725 844 | 31.12.2023 |
2,82 % | Boxer Capital, L.L.C. | 1 900 000 | 0 | 31.12.2023 |
2,78 % | Franklin Advisers, Inc. | 1 875 391 | -9135 | 31.12.2023 |
1,95 % | Driehaus Capital Management, LLC | 1 311 013 | 175 818 | 31.12.2023 |
1,83 % | Balyasny Asset Management LP | 1 233 238 | 372 879 | 31.12.2023 |
1,83 % | Pictet Asset Management Ltd. | 1 232 808 | 268 961 | 31.12.2023 |
1,74 % | Medicxi Ventures (UK) LLP | 1 169 028 | -430 972 | 31.03.2024 |
1,69 % | Lynx1 Capital Advisors LLC | 1 135 225 | -15 000 | 31.12.2023 |
1,32 % | Avoro Capital Advisors LLC | 888 888 | 444 444 | 31.12.2023 |
1,29 % | Rock Springs Capital Management LP | 872 069 | 33 641 | 31.12.2023 |
1,17 % | BlackRock Financial Management, Inc. | 789 986 | 242 | 31.12.2023 |
1,11 % | Two Sigma Investments, LP | 746 553 | 469 263 | 31.12.2023 |
1,11 % | Frazier Healthcare Partners | 746 479 | 0 | 31.12.2023 |
1,08 % | Fidelity Management & Research Company LLC | 730 453 | -44 500 | 31.12.2023 |
1,06 % | Fairmount Funds Management LLC | 717 254 | -1 164 091 | 31.12.2023 |
1,03 % | Millennium Management LLC | 693 327 | 64 128 | 31.12.2023 |
0,96 % | SilverArc Capital Management, LLC | 645 581 | 145 581 | 31.12.2023 |
0,79 % | Janus Henderson Investors | 531 044 | 332 756 | 31.12.2023 |
0,77 % | 5AM Ventures | 521 531 | 521 531 | 31.12.2023 |
0,74 % | StemPoint Capital LP | 501 806 | 501 806 | 31.12.2023 |
0,71 % | Candriam Luxembourg S.A. | 480 227 | 0 | 29.02.2024 |
0,68 % | Dafna Capital Management, LLC | 454 870 | -30 000 | 31.12.2023 |
0,60 % | Carmignac Gestion | 403 861 | -50 470 | 31.12.2023 |
0,58 % | Saturn V Capital Management LLC | 389 333 | 349 267 | 31.12.2023 |
0,58 % | BlackRock Institutional Trust Company, N.A. | 388 708 | -33 448 | 31.12.2023 |
0,56 % | Goldman Sachs & Company, Inc. | 378 477 | 172 500 | 31.12.2023 |
0,55 % | Braidwell LP | 370 679 | -1 530 658 | 31.12.2023 |
0,53 % | Aquilo Capital Management, LLC | 355 109 | -75 000 | 31.12.2023 |
0,49 % | Medical Strategy GmbH | 331 487 | 0 | 31.12.2023 |
0,49 % | Adage Capital Management, L.P. | 330 000 | 230 000 | 31.12.2023 |
0,45 % | Soleus Capital Management, L.P. | 302 577 | -81 913 | 31.12.2023 |
0,45 % | Morgan Stanley & Co. LLC | 302 531 | 113 386 | 31.12.2023 |
0,42 % | Citadel Advisors LLC | 280 251 | 277 066 | 31.12.2023 |
0,41 % | Ally Bridge Group NY LLC | 274 923 | 53 539 | 31.12.2023 |
0,38 % | Candriam Belgium S.A. | 257 419 | -605 657 | 30.11.2023 |
0,36 % | Woodline Partners LP | 243 229 | 0 | 31.12.2023 |
0,35 % | State Street Global Advisors (US) | 235 688 | 15 910 | 31.12.2023 |
0,34 % | Sphera Funds Management Ltd. | 230 333 | -23 000 | 31.12.2023 |
0,31 % | BlackRock Advisors (UK) Limited | 207 715 | -129 | 31.03.2024 |
0,28 % | BlackRock Asset Management Ireland Limited | 187 172 | 2031 | 31.12.2023 |
0,28 % | T. Rowe Price Investment Management, Inc. | 186 300 | 186 300 | 31.03.2024 |
0,25 % | AllianceBernstein L.P. | 169 098 | -23 186 | 31.12.2023 |
0,23 % | Parkman Healthcare Partners LLC | 157 817 | 27 082 | 31.12.2023 |
0,23 % | Liu (Hui) | 156 016 | 98 085 | 15.03.2024 |
0,23 % | Lundberg (Sven Ante) | 152 071 | 0 | 15.03.2024 |
0,21 % | The Vanguard Group, Inc. | 142 833 | -27 093 | 31.12.2023 |
0,21 % | Platinum Asset Management | 142 029 | 0 | 31.12.2023 |
0,20 % | Nan Fung Life Sciences | 137 038 | 0 | 31.12.2023 |
0,20 % | HighVista Strategies LLC | 133 572 | 10 941 | 31.12.2023 |
0,19 % | Cubist Systematic Strategies, LLC | 126 505 | 126 505 | 31.12.2023 |
0,18 % | UBS O'Connor LLC | 121 300 | -30 806 | 31.12.2023 |
0,17 % | Eversept Partners, LP | 115 726 | -18 284 | 31.12.2023 |
0,16 % | DWS Investment GmbH | 110 000 | 0 | 31.12.2023 |
0,15 % | Morgan Stanley Investment Management Inc. (US) | 99 934 | -51 326 | 31.12.2023 |
0,14 % | Allianz Global Investors U.S. LLC_NLE | 93 975 | 0 | 30.09.2023 |
0,14 % | Voya Investment Management LLC | 93 975 | 0 | 31.12.2023 |
0,13 % | Wellington Management Japan Pte Ltd | 89 295 | -61 818 | 30.06.2023 |
0,13 % | Hudson Bay Capital Management LP | 87 200 | -80 618 | 31.12.2023 |
0,13 % | Nomura Asset Management Co., Ltd. | 87 000 | 87 000 | 30.11.2023 |
0,11 % | Iwicki (Mark T.) | 73 576 | 73 576 | 15.03.2024 |
0,11 % | Schweizerische Nationalbank | 72 654 | -20 700 | 31.12.2023 |
0,10 % | Algert Global LLC | 68 933 | -1549 | 31.12.2023 |
0,09 % | BNP Paribas Securities Corp. North America | 62 825 | 36 160 | 31.12.2023 |
0,09 % | Norges Bank Investment Management (NBIM) | 60 300 | -14 700 | 31.12.2023 |
0,09 % | D. E. Shaw & Co., L.P. | 59 033 | 59 033 | 31.12.2023 |
0,08 % | Deka Vermögensmanagement GmbH | 56 000 | 31 000 | 31.12.2023 |
0,08 % | HBM Partners AG | 56 000 | 5000 | 30.09.2023 |
0,08 % | Geode Capital Management, L.L.C. | 53 608 | 150 | 31.12.2023 |
0,07 % | Campbell & Company, Inc. | 48 007 | 48 007 | 31.12.2023 |
0,07 % | MFS Investment Management | 47 926 | -1447 | 29.02.2024 |
0,07 % | Invesco Capital Management LLC | 46 208 | 46 208 | 31.12.2023 |
0,07 % | Jump Financial, LLC | 46 120 | 46 120 | 31.12.2023 |
0,07 % | Credit Suisse Funds AG | 44 990 | -3675 | 31.12.2023 |
0,06 % | Nuveen LLC | 43 677 | -14 214 | 31.12.2023 |
0,06 % | Trexquant Investment LP | 40 489 | 23 503 | 31.12.2023 |
0,06 % | Alps Advisors, Inc. | 40 128 | 40 128 | 31.12.2023 |
0,06 % | ExodusPoint Capital Management, LP | 39 087 | 39 087 | 31.12.2023 |
0,06 % | T. Rowe Price Associates, Inc. | 39 064 | 9569 | 29.02.2024 |
0,06 % | Assenagon Asset Management S.A. | 38 383 | 2820 | 29.02.2024 |
0,06 % | Northern Trust Investments, Inc. | 38 022 | 952 | 31.12.2023 |
0,06 % | HRT Financial LP | 37 773 | 11 265 | 31.12.2023 |
0,06 % | Schonfeld Strategic Advisors LLC | 37 600 | -201 770 | 31.12.2023 |
0,06 % | UBS Asset Management (Americas), Inc. | 37 426 | -1093 | 31.03.2023 |
0,05 % | Atom Investors LP | 35 544 | 21 976 | 31.12.2023 |
0,05 % | First Trust Advisors L.P. | 35 185 | 1247 | 31.12.2023 |
0,05 % | Legal & General Investment Management Ltd. | 34 621 | -1848 | 31.12.2023 |
0,05 % | California State Teachers Retirement System | 32 809 | -4759 | 31.12.2023 |
0,04 % | State of Wisconsin Investment Board | 25 618 | -1737 | 31.12.2023 |
0,04 % | Deka Investment GmbH | 25 000 | 20 600 | 31.12.2022 |
0,04 % | Sanders Morris LLC | 24 870 | 0 | 31.03.2024 |
0,04 % | Susquehanna Portfolio Strategies, LLC | 24 628 | 24 628 | 31.12.2023 |
0,04 % | Tudor Investment Corporation | 24 443 | 805 | 31.12.2023 |