14,96185 % | Fidelity Management & Research Company LLC | 7.513.840 | 8.426 | 30/06/2024 |
9,92223 % | EcoR1 Capital, LLC | 4.982.945 | 1.968.193 | 30/06/2024 |
6,02575 % | Springer Timothy A | 3.026.133 | -4.608.052 | 16/08/2024 |
5,86095 % | BlackRock Institutional Trust Company, N.A. | 2.943.371 | 175.446 | 30/06/2024 |
5,02986 % | Invus Public Equities Advisors, LLC | 2.525.998 | 312.810 | 30/06/2024 |
4,40149 % | The Vanguard Group, Inc. | 2.210.429 | -45.246 | 30/06/2024 |
4,28538 % | T. Rowe Price Associates, Inc. | 2.152.117 | -318.042 | 30/06/2024 |
3,96386 % | Polaris Venture Partners | 1.990.651 | 0 | 01/04/2024 |
3,55078 % | Woodline Partners LP | 1.783.202 | 1.683.202 | 30/06/2024 |
3,26186 % | State Street Global Advisors (US) | 1.638.108 | -1.027.402 | 30/06/2024 |
2,90980 % | Point72 Asset Management, L.P. | 1.461.302 | -3.225.798 | 30/06/2024 |
2,02691 % | Pictet Asset Management Ltd. | 1.017.912 | -168.996 | 30/06/2024 |
1,98128 % | Federated Hermes Global Investment Management Corp. | 995.000 | 0 | 30/06/2024 |
1,93147 % | Geode Capital Management, L.L.C. | 969.986 | 74.786 | 30/06/2024 |
1,22356 % | Tipirneni (Praveen P) | 614.474 | -42.460 | 16/08/2024 |
1,21963 % | OrbiMed Advisors, LLC | 612.500 | 54.000 | 30/06/2024 |
1,15098 % | Two Sigma Investments, LP | 578.020 | -63.831 | 30/06/2024 |
1,06458 % | Goldman Sachs & Company, Inc. | 534.630 | 103.925 | 30/06/2024 |
0,96835 % | SilverArc Capital Management, LLC | 486.306 | 2.334 | 30/06/2024 |
0,73553 % | MPM BioImpact LLC | 369.384 | 44.051 | 30/06/2024 |
0,65282 % | Charles Schwab Investment Management, Inc. | 327.844 | 1.147 | 30/06/2024 |
0,64397 % | BlackRock Financial Management, Inc. | 323.403 | 27.905 | 30/06/2024 |
0,62639 % | Northern Trust Investments, Inc. | 314.575 | -646 | 30/06/2024 |
0,49895 % | Affinity Asset Advisors LLC | 250.573 | 25.573 | 30/06/2024 |
0,48772 % | Wellington Management Company, LLP | 244.931 | -5.569.515 | 31/07/2024 |
0,46147 % | Dafna Capital Management, LLC | 231.748 | 0 | 30/06/2024 |
0,42685 % | Fiduciary Trust Company | 214.366 | 0 | 30/06/2024 |
0,42643 % | Candriam Belgium S.A. | 214.154 | -35.779 | 30/06/2024 |
0,41463 % | Dimensional Fund Advisors, L.P. | 208.225 | -12.937 | 30/06/2024 |
0,32256 % | Citadel Advisors LLC | 161.988 | -704.910 | 30/06/2024 |
0,32038 % | Voloridge Investment Management, LLC | 160.896 | 160.896 | 30/06/2024 |
0,31829 % | Omega Fund Management, LLC | 159.846 | 0 | 30/06/2024 |
0,30430 % | D. E. Shaw & Co., L.P. | 152.819 | -61.637 | 30/06/2024 |
0,29980 % | AllianceBernstein L.P. | 150.558 | 38.776 | 30/06/2024 |
0,29132 % | Nomura Asset Management Co., Ltd. | 146.300 | 146.300 | 30/11/2023 |
0,26898 % | Morgan Stanley & Co. LLC | 135.082 | -67.468 | 30/06/2024 |
0,26140 % | Jane Street Capital, L.L.C. | 131.276 | 85.314 | 30/06/2024 |
0,25826 % | Nuveen LLC | 129.698 | 3.897 | 30/06/2024 |
0,25679 % | Medical Strategy GmbH | 128.962 | -313.051 | 31/12/2023 |
0,23456 % | BlackRock Investment Management, LLC | 117.794 | 24.237 | 30/06/2024 |
0,22677 % | Ensign Peak Advisors, Inc. | 113.883 | -27.340 | 30/06/2024 |
0,22322 % | TD Asset Management Inc. | 112.100 | -13.800 | 30/06/2024 |
0,19702 % | Goldman Sachs Asset Management, L.P. | 98.943 | -14.297 | 30/06/2024 |
0,19167 % | BNY Mellon Asset Management | 96.256 | 5.819 | 30/06/2024 |
0,17675 % | Barclays Bank PLC | 88.766 | 44.039 | 30/06/2024 |
0,17118 % | Manulife Investment Management (North America) Limited | 85.966 | 4.021 | 30/06/2024 |
0,17111 % | Susquehanna International Group, LLP | 85.932 | 16.033 | 30/06/2024 |
0,16771 % | BofA Global Research (US) | 84.223 | -30.339 | 30/06/2024 |
0,15940 % | Allianz Global Investors GmbH | 80.049 | -13.621 | 30/06/2024 |
0,15838 % | Jump Financial, LLC | 79.539 | 67.387 | 30/06/2024 |
0,15485 % | Capital Fund Management S.A. | 77.767 | 58.100 | 30/06/2024 |
0,14846 % | Rafferty Asset Management LLC | 74.557 | -146.237 | 30/06/2024 |
0,14536 % | HOOPP Investment Management | 73.000 | 73.000 | 30/06/2024 |
0,13267 % | Atom Investors LP | 66.628 | -20.002 | 30/06/2024 |
0,13019 % | Rhumbline Advisers Ltd. Partnership | 65.379 | 13.677 | 30/06/2024 |
0,12498 % | BlackRock Asset Management Ireland Limited | 62.765 | 3.150 | 30/06/2024 |
0,11728 % | Schweizerische Nationalbank | 58.900 | 0 | 30/06/2024 |
0,11542 % | Connor, Clark & Lunn Investment Management Ltd. | 57.965 | -46.665 | 30/06/2024 |
0,10966 % | T. Rowe Price International Ltd | 55.070 | 1.643 | 30/06/2024 |
0,10745 % | Mellon Investments Corporation | 53.963 | 21.651 | 30/06/2024 |
0,10702 % | PGIM Quantitative Solutions LLC | 53.747 | -26.180 | 30/06/2024 |
0,09490 % | Saturn V Capital Management LP | 47.660 | -37.972 | 30/06/2024 |
0,08606 % | BlackRock Investment Management (UK) Ltd. | 43.220 | 9.516 | 30/06/2024 |
0,08256 % | UBS Financial Services, Inc. | 41.460 | -107.534 | 30/06/2024 |
0,07777 % | Alps Advisors, Inc. | 39.054 | 3.762 | 30/06/2024 |
0,06795 % | Millennium Management LLC | 34.125 | 34.125 | 30/06/2024 |
0,06593 % | Algert Global LLC | 33.108 | 16.531 | 30/06/2024 |
0,06322 % | Wellington Management Singapore Pte. Ltd. | 31.751 | 31.751 | 31/03/2024 |
0,06322 % | Wellington Management Japan Pte Ltd | 31.751 | -13.447 | 30/06/2023 |
0,05983 % | California State Teachers Retirement System | 30.048 | -631 | 30/06/2024 |
0,05952 % | Carmignac Gestion | 29.892 | 29.892 | 31/07/2024 |
0,05817 % | Legal & General Investment Management Ltd. | 29.214 | -185 | 30/06/2024 |
0,05679 % | Victory Capital Management Inc. | 28.520 | -580 | 30/06/2024 |
0,05645 % | UBS Asset Management (Americas), Inc. | 28.350 | 28.350 | 31/03/2023 |
0,05350 % | First Trust Advisors L.P. | 26.867 | 26.867 | 30/06/2024 |
0,05272 % | PDT Partners, LLC | 26.474 | -34.663 | 30/06/2024 |
0,04978 % | Tudor Investment Corporation | 25.002 | -882 | 30/06/2024 |
0,04938 % | T. Rowe Price Japan, Inc. | 24.799 | 15.500 | 30/04/2024 |
0,04864 % | Aperio Group, LLC | 24.427 | 629 | 30/06/2024 |
0,04860 % | Northern Trust Global Investments | 24.409 | 1.106 | 30/06/2024 |
0,04842 % | UBS Fund Management (Switzerland) AG | 24.319 | -7.904 | 30/06/2024 |
0,04776 % | Mirae Asset Global Investments (USA) LLC | 23.986 | 4.698 | 30/06/2024 |
0,04724 % | Squarepoint Capital LLP | 23.723 | 23.723 | 30/06/2024 |
0,04607 % | American Century Investment Management, Inc. | 23.134 | 16.606 | 30/06/2024 |
0,04595 % | MetLife Investment Management, LLC | 23.077 | 3.665 | 30/06/2024 |
0,04414 % | DeVaul (William David) | 22.167 | 0 | 08/07/2024 |
0,04273 % | Y-Intercept (Hong Kong) Ltd | 21.459 | 21.459 | 30/06/2024 |
0,04267 % | Corebridge Financial Inc | 21.431 | 21.431 | 30/06/2024 |
0,04022 % | Healthinvest Partners AB | 20.199 | 5.247 | 30/06/2024 |
0,03849 % | ExodusPoint Capital Management, LP | 19.330 | 19.330 | 30/06/2024 |
0,03804 % | State of Wisconsin Investment Board | 19.105 | -993 | 30/06/2024 |
0,03743 % | SunAmerica Asset Management, LLC | 18.797 | 533 | 31/03/2024 |
0,03536 % | Edgestream Partners, L.P. | 17.760 | 17.760 | 30/06/2024 |
0,03494 % | DWS Investments UK Limited | 17.547 | -1.922 | 30/06/2024 |
0,03485 % | Wells Fargo Bank, N.A. | 17.504 | 5.837 | 30/06/2024 |
0,03418 % | Kentucky Teachers' Retirement System | 17.167 | 0 | 30/06/2024 |
0,03409 % | Citi Investment Research (US) | 17.122 | -173.223 | 30/06/2024 |
0,03380 % | JPMorgan Private Bank (United States) | 16.976 | 2.137 | 30/06/2024 |
0,03286 % | Guggenheim Investments | 16.502 | -7.291 | 31/08/2024 |
0,03256 % | UBS Asset Management (Switzerland) | 16.354 | 4.400 | 30/06/2024 |