2,53991 % | Matrix Capital Management Company, LP | 38.974.185 | 0 | 31/12/2023 |
1,78590 % | EcoR1 Capital, LLC | 27.404.070 | 8.500.000 | 08/03/2024 |
1,11307 % | New Enterprise Associates (NEA) | 17.079.778 | 0 | 01/04/2024 |
1,03698 % | Baillie Gifford & Co. | 15.912.140 | -1.235.269 | 31/12/2023 |
0,78769 % | Long Focus Capital Management LLC | 12.086.915 | 774.568 | 31/12/2023 |
0,71486 % | Baker Bros. Advisors LP | 10.969.282 | 0 | 31/12/2023 |
0,67927 % | PFM Health Sciences, LP | 10.423.135 | 0 | 31/12/2023 |
0,36204 % | MPM Capital Inc. | 5.555.461 | -731.640 | 31/12/2023 |
0,33210 % | BioImpact Capital LLC | 5.095.912 | 0 | 31/12/2023 |
0,30616 % | BofA Global Research (US) | 4.697.954 | 829 | 31/12/2023 |
0,28591 % | Tang Capital Management, LLC | 4.387.238 | -779.716 | 31/12/2023 |
0,22154 % | Citadel Advisors LLC | 3.399.514 | -150.045 | 31/12/2023 |
0,15807 % | Rock Springs Capital Management LP | 2.425.468 | -362.377 | 31/12/2023 |
0,11447 % | Morgan Stanley & Co. LLC | 1.756.546 | -95.566 | 31/12/2023 |
0,11295 % | Fidelity Management & Research Company LLC | 1.733.141 | 0 | 31/12/2023 |
0,08976 % | Syncona Portfolio Ltd | 1.377.294 | 0 | 31/12/2023 |
0,08930 % | Renaissance Technologies LLC | 1.370.239 | 342.379 | 31/12/2023 |
0,06135 % | Baillie Gifford Overseas Ltd. | 941.398 | 0 | 29/02/2024 |
0,06049 % | JPMorgan Asset Management U.K. Limited | 928.224 | 0 | 31/12/2023 |
0,04664 % | Redmile Group, LLC | 715.607 | 0 | 31/12/2023 |
0,03316 % | GSA Capital Partners LLP | 508.808 | 508.808 | 31/12/2023 |
0,03127 % | Acuitas Investments LLC | 479.789 | 25 | 31/12/2023 |
0,02874 % | Millennium Management LLC | 441.032 | 140.971 | 31/12/2023 |
0,02821 % | Rathbones Investment Management Limited | 432.818 | 0 | 31/12/2023 |
0,02493 % | Bellecapital Partners AG | 382.553 | 0 | 30/09/2023 |
0,02288 % | Dafna Capital Management, LLC | 351.064 | 0 | 31/12/2023 |
0,01990 % | State Street Global Advisors (US) | 305.336 | 6.235 | 31/12/2023 |
0,01751 % | Key Client Fiduciary Advisors, LLC | 268.655 | -67.965 | 31/03/2024 |
0,01302 % | Morgan Stanley Smith Barney LLC | 199.827 | 5.077 | 31/12/2023 |
0,01057 % | Menzel (Garry E) | 162.229 | -47.702 | 10/07/2023 |
0,00963 % | Harbor Capital Advisors, Inc. | 147.732 | 13.317 | 31/12/2023 |
0,00768 % | Geode Capital Management, L.L.C. | 117.909 | 0 | 31/12/2023 |
0,00642 % | Marquette Wealth Management | 98.589 | -760 | 31/12/2023 |
0,00636 % | Jane Street Capital, L.L.C. | 97.580 | 97.580 | 31/12/2023 |
0,00594 % | BlackRock Financial Management, Inc. | 91.131 | -22.855 | 31/12/2023 |
0,00587 % | ACT Capital Management, L.L.C. | 90.000 | 0 | 30/09/2022 |
0,00541 % | AllianceBernstein L.P. | 82.961 | 41.988 | 29/02/2024 |
0,00537 % | Bertrand William C Jr | 82.353 | -32.818 | 17/01/2024 |
0,00533 % | Rawcliffe Adrian | 81.781 | -68.586 | 17/01/2024 |
0,00528 % | BlackRock Institutional Trust Company, N.A. | 81.027 | -975.206 | 31/12/2023 |
0,00456 % | Renta 4 Gestora, S.G.I.I.C., S.A. | 70.046 | 32.829 | 31/12/2023 |
0,00390 % | HRT Financial LP | 59.906 | 59.906 | 31/12/2023 |
0,00390 % | Two Sigma Investments, LP | 59.837 | -64.674 | 31/12/2023 |
0,00370 % | Susquehanna International Group, LLP | 56.846 | -110.042 | 31/12/2023 |
0,00366 % | Wells Fargo Advisors | 56.177 | 1.432 | 31/12/2023 |
0,00354 % | Piccina (Cintia) | 54.359 | 54.359 | 03/04/2023 |
0,00327 % | Oppenheimer Asset Management Inc. | 50.103 | -18.068 | 31/12/2023 |
0,00326 % | Barclays Bank PLC | 50.061 | 0 | 31/12/2023 |
0,00316 % | Lunger (John) | 48.517 | -32.024 | 17/01/2024 |
0,00241 % | XTX Markets LLC | 36.977 | 36.977 | 31/12/2023 |
0,00239 % | Northern Trust Investments, Inc. | 36.602 | 0 | 31/12/2023 |
0,00226 % | Cubist Systematic Strategies, LLC | 34.607 | 34.607 | 31/12/2023 |
0,00210 % | Wealth Enhancement Advisory Services, LLC | 32.239 | 0 | 31/03/2024 |
0,00203 % | Main Street Financial Solutions, LLC | 31.190 | 0 | 31/12/2023 |
0,00200 % | CSS, LLC | 30.702 | -60.000 | 31/12/2023 |
0,00199 % | DLK Investment Management, LLC | 30.512 | 0 | 31/03/2024 |
0,00196 % | Simon Quick Advisors, LLC | 30.000 | 0 | 31/03/2024 |
0,00196 % | Janney Montgomery Scott LLC | 30.000 | 0 | 31/12/2023 |
0,00187 % | Prosperity Wealth Management, Inc. | 28.620 | -2.000 | 31/12/2023 |
0,00185 % | Virtu Americas LLC | 28.406 | 28.406 | 31/12/2023 |
0,00179 % | X-Square Capital, LLC | 27.425 | 654 | 31/12/2023 |
0,00178 % | Stifel, Nicolaus & Company, Incorporated | 27.259 | -2.574 | 31/12/2023 |
0,00173 % | HSBC Global Asset Management (UK) Limited | 26.504 | 440 | 31/12/2023 |
0,00170 % | JTC Employer Solutions Trusteee Ltd | 26.156 | 26.156 | 31/03/2024 |
0,00161 % | UBS Financial Services, Inc. | 24.693 | 16.935 | 31/12/2023 |
0,00156 % | Alleva (Lawrence M) | 23.894 | 0 | 03/04/2023 |
0,00150 % | Newman, Dignan & Sheerar, Inc. | 23.031 | 23.031 | 31/12/2023 |
0,00150 % | Hunter Associates Investment Management LLC | 23.000 | -1.000 | 31/12/2023 |
0,00136 % | Northern Trust Global Investments | 20.821 | 0 | 31/12/2023 |
0,00112 % | CAPTRUST Financial Advisors | 17.254 | -4.670 | 31/12/2023 |
0,00109 % | Commonwealth Financial Network | 16.758 | -15.117 | 31/12/2023 |
0,00106 % | LoCorr Fund Management, LLC | 16.257 | 3.466 | 31/12/2022 |
0,00104 % | Wood (Gavin) | 16.000 | 0 | 03/04/2023 |
0,00104 % | Goldman Sachs & Company, Inc. | 15.979 | -41.632 | 31/12/2023 |
0,00102 % | COLUMBIA ADVISORY PARTNERS LLC | 15.585 | 15.585 | 31/03/2024 |
0,00094 % | Ballentine Partners, LLC | 14.489 | 14.489 | 31/03/2024 |
0,00091 % | Norry (Elliot) | 13.917 | -32.371 | 17/01/2024 |
0,00085 % | Procyon Advisors, LLC | 13.000 | 13.000 | 31/03/2024 |
0,00081 % | Brewer (Joanna Elizabeth) | 12.442 | 12.442 | 03/04/2023 |
0,00069 % | Tower Research Capital LLC | 10.664 | 2.627 | 31/12/2023 |
0,00067 % | Raymond James & Associates, Inc. | 10.218 | -151 | 31/12/2023 |
0,00067 % | Scientech Research LLC | 10.205 | 10.205 | 31/12/2023 |
0,00065 % | Sigal Family Investments, LLC | 10.000 | 0 | 03/04/2023 |
0,00057 % | Sigal (Charles Elliott) | 8.823 | 0 | 03/04/2023 |
0,00048 % | BlackRock Investment Management (UK) Ltd. | 7.423 | 0 | 31/12/2023 |
0,00043 % | Goldman Sachs Asset Management International | 6.547 | 0 | 31/01/2024 |
0,00042 % | State Street Global Advisors (UK) Ltd. | 6.400 | 6.400 | 29/02/2024 |
0,00041 % | Osaic Holdings, Inc. | 6.258 | -4.200 | 31/12/2023 |
0,00039 % | Global Retirement Partners, LLC | 6.000 | 0 | 31/12/2023 |
0,00039 % | Rhumbline Advisers Ltd. Partnership | 5.912 | 330 | 31/12/2023 |
0,00038 % | Putnam Investment Management, L.L.C. | 5.801 | -19.595 | 28/02/2023 |
0,00030 % | Lindbrook Capital, LLC | 4.610 | 0 | 31/12/2023 |
0,00027 % | Lazard Asset Management, L.L.C. | 4.160 | -193 | 31/12/2023 |
0,00020 % | Wetzel Investment Advisors Inc | 3.000 | 3.000 | 31/12/2023 |
0,00016 % | GF Fund Management Co., Ltd. | 2.495 | -542 | 30/06/2023 |
0,00014 % | BNP Paribas Securities Corp. North America | 2.162 | -1.891 | 31/12/2023 |
0,00014 % | Qube Research & Technologies Ltd | 2.087 | -19.474 | 31/12/2023 |
0,00007 % | Sandy Spring Bank | 1.050 | 0 | 31/12/2023 |
0,00004 % | RBC Capital Markets Wealth Management | 592 | 567 | 31/12/2023 |
0,00003 % | Carmichael Hill & Associates Inc | 525 | 0 | 31/12/2023 |