14,83625 % | Vivo Capital, LLC | 5.766.851 | -1.550.000 | 29/08/2024 |
10,71180 % | Janus Henderson Investors | 4.163.678 | 804.805 | 30/09/2024 |
8,24537 % | Perceptive Advisors LLC | 3.204.976 | 130.434 | 30/06/2024 |
7,92927 % | Nantahala Capital Management, LLC | 3.082.107 | 671.728 | 30/06/2024 |
7,34267 % | Adage Capital Management, L.P. | 2.854.094 | 910.574 | 30/06/2024 |
5,38118 % | Avoro Capital Advisors LLC | 2.091.666 | 466.666 | 30/06/2024 |
3,85717 % | The Vanguard Group, Inc. | 1.499.283 | 533.098 | 30/06/2024 |
3,66607 % | Commodore Capital LP | 1.425.000 | 1.255.467 | 30/06/2024 |
3,63940 % | BlackRock Institutional Trust Company, N.A. | 1.414.633 | 1.115.437 | 30/06/2024 |
3,08721 % | Vestal Point Capital, LP | 1.200.000 | -50.000 | 30/06/2024 |
2,57303 % | State Street Global Advisors (US) | 1.000.136 | 29.566 | 30/06/2024 |
2,25281 % | Frazier Life Sciences Management, L.P. | 875.667 | 0 | 30/06/2024 |
1,86746 % | Abingworth Management Limited | 725.881 | -2.131.923 | 17/10/2024 |
1,61059 % | Anish (Bhatnagar) | 626.035 | -21.633 | 01/10/2024 |
1,42619 % | Sofinnova Investments, Inc | 554.359 | 403.584 | 30/06/2024 |
1,41497 % | TCG Crossover Management, LLC | 550.000 | 0 | 30/06/2024 |
1,40556 % | Emerald Advisers LLC | 546.342 | 11.915 | 30/09/2024 |
1,38012 % | Holocene Advisors, LP | 536.451 | 536.451 | 30/06/2024 |
1,28904 % | Samlyn Capital, LLC | 501.049 | 282.122 | 30/06/2024 |
1,25831 % | Geode Capital Management, L.L.C. | 489.107 | 322.086 | 30/06/2024 |
1,18797 % | T. Rowe Price Associates, Inc. | 461.762 | 309.142 | 30/06/2024 |
1,17962 % | Millennium Management LLC | 458.520 | 366.295 | 30/06/2024 |
1,14600 % | Ikarian Capital LLC | 445.451 | -119.960 | 30/06/2024 |
1,11078 % | Pictet Asset Management Ltd. | 431.760 | 97.908 | 30/06/2024 |
1,01115 % | Wellington Management Company, LLP | 393.035 | 39.554 | 30/06/2024 |
0,86471 % | BlackRock Financial Management, Inc. | 336.114 | 330.723 | 30/06/2024 |
0,82121 % | Woodline Partners LP | 319.205 | 212.745 | 30/06/2024 |
0,77180 % | Ghost Tree Capital, LLC | 300.000 | 100.000 | 30/06/2024 |
0,73620 % | Ally Bridge Group NY LLC | 286.162 | -50.324 | 30/06/2024 |
0,63600 % | Balyasny Asset Management LP | 247.214 | 95.596 | 30/06/2024 |
0,55008 % | Mario (Ernest B) | 213.818 | 6.500 | 06/06/2024 |
0,54775 % | Altium Capital Management LP | 212.909 | 60.000 | 30/06/2024 |
0,51721 % | Goldman Sachs & Company, Inc. | 201.038 | -10.879 | 30/06/2024 |
0,50771 % | Medical Strategy GmbH | 197.347 | 25.000 | 30/06/2024 |
0,37357 % | Schuler (Jack W) | 145.207 | -372.143 | 24/05/2023 |
0,37332 % | Driehaus Capital Management, LLC | 145.110 | 51.656 | 30/06/2024 |
0,36384 % | Allspring Global Investments, LLC | 141.424 | 7.840 | 30/09/2024 |
0,28299 % | Soros Fund Management, L.L.C. | 110.000 | 10.000 | 30/06/2024 |
0,26761 % | Boothbay Fund Management, LLC | 104.020 | -28.011 | 30/06/2024 |
0,24292 % | Artia Global Partners LP | 94.424 | 53.500 | 30/06/2024 |
0,23303 % | Principal Global Investors (Equity) | 90.580 | -6.483 | 31/08/2024 |
0,21540 % | Caption Management, LLC | 83.726 | 43.726 | 30/06/2024 |
0,21532 % | Morgan Stanley & Co. LLC | 83.696 | 4.509 | 30/06/2024 |
0,21393 % | Hirano (Patricia C) | 83.153 | -3.108 | 01/10/2024 |
0,21185 % | Mackaness (James H) | 82.348 | -8.077 | 01/10/2024 |
0,20959 % | Yen (Kristen) | 81.466 | -3.108 | 01/10/2024 |
0,19166 % | Polar Asset Management Partners Inc. | 74.500 | 74.500 | 30/06/2024 |
0,18009 % | 683 Capital Management LLC | 70.000 | -8.000 | 30/06/2024 |
0,17137 % | BofA Global Research (US) | 66.612 | -2.346 | 30/06/2024 |
0,16173 % | BlackRock Investment Management, LLC | 62.863 | 62.863 | 30/06/2024 |
0,16084 % | Charles Schwab Investment Management, Inc. | 62.517 | 55.322 | 30/06/2024 |
0,15040 % | Nuveen LLC | 58.460 | 58.460 | 30/06/2024 |
0,14862 % | Norges Bank Investment Management (NBIM) | 57.770 | 57.770 | 30/06/2024 |
0,14802 % | TD Asset Management Inc. | 57.534 | 36.534 | 30/06/2024 |
0,14488 % | Qube Research & Technologies Ltd | 56.316 | -22.184 | 30/06/2024 |
0,14401 % | Northern Trust Investments, Inc. | 55.978 | 22.401 | 30/06/2024 |
0,14383 % | BNY Mellon Asset Management | 55.906 | 55.906 | 30/06/2024 |
0,13897 % | Schonfeld Strategic Advisors LLC | 54.019 | 8.547 | 30/06/2024 |
0,13876 % | Rafferty Asset Management LLC | 53.937 | -52.207 | 30/06/2024 |
0,12711 % | Manulife Investment Management (North America) Limited | 49.408 | 27.020 | 30/06/2024 |
0,10291 % | Manning (Meredith S.) | 40.000 | 40.000 | 17/07/2024 |
0,10272 % | Adar1 Capital Management LLC | 39.929 | 39.929 | 30/06/2024 |
0,10081 % | Susquehanna International Group, LLP | 39.184 | 30.162 | 30/06/2024 |
0,09274 % | Harbor Capital Advisors, Inc. | 36.048 | 34.807 | 30/09/2024 |
0,09028 % | Jefferies LLC | 35.091 | -800 | 30/06/2024 |
0,09004 % | Huang (Michael F) | 35.000 | 35.000 | 17/07/2024 |
0,08734 % | UBS Financial Services, Inc. | 33.950 | -19.855 | 30/06/2024 |
0,08650 % | Columbia Threadneedle Investments (US) | 33.624 | 2.484 | 30/06/2024 |
0,08453 % | Mellon Investments Corporation | 32.858 | 32.858 | 30/06/2024 |
0,08117 % | MFS Investment Management | 31.550 | 0 | 31/08/2024 |
0,08082 % | BlackRock Investment Management (UK) Ltd. | 31.414 | 25.044 | 30/06/2024 |
0,07718 % | Hudson Bay Capital Management LP | 30.000 | 30.000 | 30/06/2024 |
0,07498 % | Rhumbline Advisers Ltd. Partnership | 29.144 | 29.144 | 30/06/2024 |
0,07409 % | Schweizerische Nationalbank | 28.800 | -1.300 | 30/06/2024 |
0,07307 % | Alps Advisors, Inc. | 28.401 | 6.887 | 30/06/2024 |
0,06930 % | J. Goldman & Co., L.P. | 26.938 | 26.938 | 30/06/2024 |
0,06432 % | Maplelane Capital, LLC | 25.000 | 0 | 30/06/2024 |
0,06331 % | AllianceBernstein L.P. | 24.610 | 24.610 | 30/06/2024 |
0,05423 % | Barclays Bank PLC | 21.078 | 459 | 30/06/2024 |
0,05357 % | Alpine Global Management, LLC | 20.824 | 20.824 | 30/06/2024 |
0,05067 % | Checkpoint Capital L.P. | 19.695 | 19.695 | 30/06/2024 |
0,04623 % | BlackRock Asset Management Ireland Limited | 17.970 | 2.629 | 30/06/2024 |
0,04554 % | Tudor Investment Corporation | 17.702 | 1.508 | 30/06/2024 |
0,04490 % | Legal & General Investment Management Ltd. | 17.452 | 5.169 | 30/06/2024 |
0,04139 % | T. Rowe Price International Ltd | 16.090 | 11.228 | 30/06/2024 |
0,03962 % | Harris (William G) | 15.401 | 6.500 | 06/06/2024 |
0,03859 % | SilverArc Capital Management, LLC | 15.000 | 15.000 | 30/06/2024 |
0,03859 % | UBS O'Connor LLC | 15.000 | 15.000 | 30/06/2024 |
0,03815 % | California State Teachers Retirement System | 14.827 | 1.047 | 30/06/2024 |
0,03620 % | Jane Street Capital, L.L.C. | 14.070 | -768 | 30/06/2024 |
0,03485 % | Volck (Birgitte) | 13.545 | 6.500 | 06/06/2024 |
0,03393 % | Cinctive Capital Management LP | 13.190 | 13.190 | 30/06/2024 |
0,03344 % | Bir (Dawn Carter) | 13.000 | 13.000 | 15/08/2024 |
0,03332 % | NEOS Investment Management, LLC | 12.950 | 1.311 | 30/06/2024 |
0,03120 % | Aspiriant, LLC | 12.128 | 0 | 30/09/2024 |
0,03044 % | Corebridge Financial Inc | 11.832 | 11.832 | 30/06/2024 |
0,03044 % | SunAmerica Asset Management, LLC | 11.832 | 0 | 31/07/2024 |
0,02817 % | Citi Investment Research (US) | 10.948 | -86.806 | 30/06/2024 |
0,02760 % | Victory Capital Management Inc. | 10.727 | 2.236 | 30/06/2024 |
0,02733 % | Invesco Advisers, Inc. | 10.625 | 10.262 | 30/06/2024 |