9,35998 % | BVF Partners L.P. | 3.466.000 | 3.466.000 | 30/06/2024 |
8,65716 % | Sullivan (Brian F) | 3.205.746 | 234.128 | 20/08/2024 |
6,37937 % | Perceptive Advisors LLC | 2.362.279 | 0 | 30/06/2024 |
6,16881 % | Morgan Stanley & Co. LLC | 2.284.309 | -1.768 | 30/06/2024 |
5,06340 % | Baker Bros. Advisors LP | 1.874.978 | 322.500 | 30/06/2024 |
4,22789 % | The Vanguard Group, Inc. | 1.565.589 | 736.992 | 30/06/2024 |
4,14529 % | Eventide Asset Management, LLC | 1.535.000 | 145.000 | 30/06/2024 |
3,95383 % | Commodore Capital LP | 1.464.105 | -91.849 | 30/06/2024 |
3,60553 % | BlackRock Institutional Trust Company, N.A. | 1.335.129 | 323.456 | 30/06/2024 |
3,58345 % | Samlyn Capital, LLC | 1.326.953 | 637.190 | 30/06/2024 |
3,37564 % | New Enterprise Associates (NEA) | 1.250.001 | 0 | 30/06/2024 |
3,37564 % | Laing (Lance G Ph.D.) | 1.250.000 | 0 | 09/08/2024 |
3,27083 % | Soleus Capital Management, L.P. | 1.211.187 | -520.151 | 30/06/2024 |
2,53251 % | Balyasny Asset Management LP | 937.787 | 55.853 | 30/06/2024 |
2,26033 % | PFM Health Sciences, LP | 837.002 | 340.000 | 30/06/2024 |
2,05493 % | Saturn V Capital Management LP | 760.941 | 760.941 | 30/06/2024 |
1,64866 % | Vivo Capital, LLC | 610.500 | 610.500 | 30/06/2024 |
1,39520 % | Braidwell LP | 516.643 | 516.643 | 30/06/2024 |
1,33365 % | Geode Capital Management, L.L.C. | 493.851 | 144.129 | 30/06/2024 |
1,27757 % | Morgan Stanley Investment Management Inc. (US) | 473.086 | 472.945 | 30/06/2024 |
1,24718 % | CAPTRUST Financial Advisors | 461.830 | -5.415 | 30/06/2024 |
1,18579 % | State Street Global Advisors (US) | 439.097 | 102.557 | 30/06/2024 |
1,16910 % | Artisan Partners Limited Partnership | 432.918 | 432.918 | 30/06/2024 |
1,16104 % | ExodusPoint Capital Management, LP | 429.934 | 101.870 | 30/06/2024 |
0,94604 % | Adage Capital Management, L.P. | 350.317 | -307.683 | 30/06/2024 |
0,82452 % | Columbia Threadneedle Investments (US) | 305.319 | 2.456 | 30/06/2024 |
0,63280 % | Dalvey David F | 234.325 | 0 | 09/08/2024 |
0,62272 % | BofA Global Research (US) | 230.595 | -9.909 | 30/06/2024 |
0,55250 % | Driehaus Capital Management, LLC | 204.592 | 78.525 | 30/06/2024 |
0,47091 % | Northern Trust Investments, Inc. | 174.377 | 13.992 | 30/06/2024 |
0,44741 % | Verition Fund Management LLC | 165.675 | -178.309 | 30/06/2024 |
0,44315 % | HOOPP Investment Management | 164.100 | 0 | 30/06/2024 |
0,41126 % | Marshall Wace LLP | 152.291 | 43.476 | 30/06/2024 |
0,27300 % | Nigon (Richard J) | 101.093 | 0 | 09/08/2024 |
0,24072 % | Two Sigma Investments, LP | 89.137 | 29.716 | 30/06/2024 |
0,20946 % | Morgan Stanley Smith Barney LLC | 77.563 | 14.758 | 30/06/2024 |
0,19721 % | Hennion & Walsh Asset Management, Inc. | 73.026 | 18.809 | 30/09/2024 |
0,18352 % | Charles Schwab Investment Management, Inc. | 67.959 | 22.646 | 30/06/2024 |
0,17553 % | Blue Owl Capital Holdings LP | 65.000 | 65.000 | 30/06/2024 |
0,17124 % | BlackRock Investment Management, LLC | 63.411 | 13.511 | 30/06/2024 |
0,17070 % | Jacob Asset Management of New York, LLC | 63.209 | -3.000 | 30/09/2023 |
0,16380 % | BlackRock Financial Management, Inc. | 60.654 | 10.730 | 30/06/2024 |
0,15981 % | Bessemer Trust Company, N.A. (US) | 59.179 | 14.544 | 31/07/2024 |
0,15915 % | Nuveen LLC | 58.934 | 26.493 | 30/06/2024 |
0,15281 % | Rafferty Asset Management LLC | 56.587 | 56.587 | 30/09/2024 |
0,14365 % | Gagnon Securities LLC | 53.192 | -338 | 30/06/2024 |
0,13923 % | Renaissance Technologies LLC | 51.556 | -23.300 | 30/06/2024 |
0,13761 % | BNY Mellon Asset Management | 50.956 | 15.612 | 30/06/2024 |
0,12152 % | Acuta Capital Partners, LLC | 45.000 | 45.000 | 30/06/2024 |
0,10287 % | JNBA Financial Advisors LLC | 38.091 | 0 | 30/06/2024 |
0,10166 % | UBS Financial Services, Inc. | 37.645 | -11.662 | 30/06/2024 |
0,10125 % | Cresset Asset Management, LLC | 37.494 | 18.984 | 30/06/2024 |
0,10110 % | Caption Management, LLC | 37.436 | 37.436 | 30/06/2024 |
0,08767 % | Rhumbline Advisers Ltd. Partnership | 32.464 | 7.049 | 30/06/2024 |
0,07863 % | Accredited Investors Wealth Management | 29.115 | 0 | 30/06/2024 |
0,07394 % | Alps Advisors, Inc. | 27.379 | 27.379 | 30/06/2024 |
0,07319 % | Connor, Clark & Lunn Investment Management Ltd. | 27.104 | -10.389 | 30/06/2024 |
0,07048 % | Northern Trust Global Investments | 26.100 | -3.273 | 30/06/2024 |
0,06673 % | New York State Common Retirement Fund | 24.709 | 0 | 30/09/2024 |
0,06482 % | Jane Street Capital, L.L.C. | 24.001 | -6.985 | 30/06/2024 |
0,06237 % | J. Goldman & Co., L.P. | 23.095 | -9.076 | 30/06/2024 |
0,06112 % | Goldman Sachs & Company, Inc. | 22.633 | 22.633 | 30/06/2024 |
0,05951 % | Wealth Enhancement Advisory Services, LLC | 22.036 | 6 | 30/09/2024 |
0,05585 % | Millennium Management LLC | 20.682 | -68.593 | 30/06/2024 |
0,05185 % | Jump Financial, LLC | 19.200 | -17.293 | 30/06/2024 |
0,05011 % | Hahne (Vicky) | 18.557 | 2.000 | 09/08/2024 |
0,04968 % | Trust Point Inc. | 18.395 | -426 | 30/09/2024 |
0,04720 % | Commonwealth Financial Network | 17.478 | 854 | 30/09/2024 |
0,04391 % | AllianceBernstein L.P. | 16.260 | 10.340 | 30/06/2024 |
0,04132 % | Mellon Investments Corporation | 15.300 | 4.199 | 30/06/2024 |
0,03920 % | Susquehanna International Group, LLP | 14.517 | 14.517 | 30/06/2024 |
0,03704 % | MetLife Investment Management, LLC | 13.715 | 4.541 | 30/06/2024 |
0,03572 % | J.P. Morgan Securities LLC | 13.228 | -39.021 | 30/06/2024 |
0,03394 % | Corebridge Financial Inc | 12.568 | 12.568 | 30/06/2024 |
0,03303 % | Citadel Advisors LLC | 12.231 | -109.599 | 30/06/2024 |
0,03147 % | Pale Fire Capital SE | 11.653 | 1.384 | 30/06/2024 |
0,02863 % | Aquatic Capital Management LLC | 10.600 | 10.600 | 30/06/2024 |
0,02836 % | Furcht (Leo M.D.) | 10.500 | 0 | 09/08/2024 |
0,02688 % | JPMorgan Private Bank (United States) | 9.955 | 3.115 | 30/06/2024 |
0,02636 % | Mirae Asset Global Investments (USA) LLC | 9.762 | 257 | 30/06/2024 |
0,02500 % | Manulife Investment Management (North America) Limited | 9.257 | 0 | 31/08/2024 |
0,02499 % | DWS Investments UK Limited | 9.253 | 441 | 30/06/2024 |
0,02431 % | SunAmerica Asset Management, LLC | 9.003 | 331 | 31/03/2024 |
0,02285 % | Buller (Richard E) | 8.460 | 1.608 | 09/08/2024 |
0,02168 % | Barclays Bank PLC | 8.029 | -4.815 | 30/06/2024 |
0,02159 % | SG Americas Securities, L.L.C. | 7.995 | 7.995 | 30/09/2024 |
0,02093 % | RBC Capital Markets Wealth Management | 7.750 | -7 | 30/06/2024 |
0,02065 % | Wells Fargo Bank, N.A. | 7.646 | 1.222 | 30/06/2024 |
0,02049 % | Vaughan Nelson Investment Management, L.P. | 7.586 | 0 | 30/06/2024 |
0,01599 % | AlphaSimplex Group, LLC | 5.920 | 5.920 | 31/08/2024 |
0,01594 % | Virtus Etf Advisers LLC | 5.901 | 5.901 | 30/06/2024 |
0,01563 % | Quest Partners, LLC | 5.788 | 1.379 | 30/06/2024 |
0,01556 % | Values First Advisors, Inc. | 5.762 | 5.762 | 30/09/2024 |
0,01512 % | Voya Investment Management LLC | 5.599 | 0 | 31/08/2024 |
0,01454 % | AQR Capital Management, LLC | 5.386 | 2.556 | 30/06/2024 |
0,01375 % | Citi Investment Research (US) | 5.092 | 1.668 | 30/06/2024 |
0,01350 % | Murphy (Polly A) | 5.000 | 0 | 09/08/2024 |
0,01345 % | Florida State Board of Administration | 4.980 | 0 | 30/06/2024 |
0,01343 % | ProShare Advisors LLC | 4.974 | 482 | 30/09/2024 |
0,00964 % | Principal Global Investors (Equity) | 3.568 | 0 | 30/09/2024 |