8,89242 % | Franklin Advisers, Inc. | 10.212.945 | -351.400 | 30/06/2024 |
8,30899 % | VR Adviser, LLC | 9.542.871 | 467.871 | 30/06/2024 |
6,96996 % | Perceptive Advisors LLC | 8.005.000 | 0 | 30/06/2024 |
6,65930 % | Janus Henderson Investors | 7.648.205 | 1.233.563 | 30/06/2024 |
5,71864 % | Propel Bio Management, LLC | 6.567.858 | 455.952 | 30/06/2024 |
5,27080 % | BlackRock Institutional Trust Company, N.A. | 6.053.514 | 5.082.151 | 30/06/2024 |
4,95436 % | Alexandria Real Estate Equities, Inc. | 5.690.077 | 1.382.258 | 31/12/2023 |
4,85389 % | Knoll Capital Management, LLC | 5.574.687 | -225.000 | 30/06/2024 |
4,72791 % | Vestal Point Capital, LP | 5.430.000 | 320.000 | 30/06/2024 |
4,63427 % | The Vanguard Group, Inc. | 5.322.460 | 2.312.170 | 30/06/2024 |
4,11286 % | Shendelman (Shoshana) | 4.723.621 | -567.102 | 14/08/2024 |
3,03433 % | Morgan Stanley & Co. LLC | 3.484.929 | 317.206 | 30/06/2024 |
2,45320 % | Simplify Asset Management Inc | 2.817.505 | 0 | 30/06/2024 |
2,41601 % | Adage Capital Management, L.P. | 2.774.784 | 125.000 | 30/06/2024 |
2,03924 % | DWS Investments UK Limited | 2.342.065 | 1.719.838 | 30/06/2024 |
2,02873 % | Tang Capital Management, LLC | 2.330.000 | 100.000 | 30/06/2024 |
1,99054 % | Frazier Life Sciences Management, L.P. | 2.286.135 | 333.278 | 30/06/2024 |
1,92540 % | StemPoint Capital LP | 2.211.320 | 194.304 | 30/06/2024 |
1,82744 % | Geode Capital Management, L.L.C. | 2.098.815 | 1.494.387 | 30/06/2024 |
1,71149 % | Alyeska Investment Group, L.P. | 1.965.646 | 522.720 | 30/06/2024 |
1,46278 % | Opaleye Management Inc. | 1.680.000 | -90.000 | 30/06/2024 |
1,44178 % | State Street Global Advisors (US) | 1.655.883 | 1.449.214 | 30/06/2024 |
1,35394 % | Rock Springs Capital Management LP | 1.555.004 | 57.086 | 30/06/2024 |
1,10554 % | Soleus Capital Management, L.P. | 1.269.714 | -295.202 | 30/06/2024 |
0,99983 % | Parkman Healthcare Partners LLC | 1.148.307 | -706.456 | 30/06/2024 |
0,87897 % | Invus Public Equities Advisors, LLC | 1.009.500 | 0 | 30/06/2024 |
0,58709 % | Sphera Funds Management Ltd. | 674.268 | 55.239 | 30/06/2024 |
0,57879 % | Peregrine Capital Management, LLC | 664.740 | -66.308 | 30/09/2024 |
0,52242 % | Logos Global Management LLC | 600.000 | -750.000 | 30/06/2024 |
0,46472 % | Schonfeld Strategic Advisors LLC | 533.729 | -1.302.913 | 30/06/2024 |
0,43397 % | Marcus (Joel S) | 498.414 | 45.000 | 06/06/2024 |
0,35958 % | Worth Venture Partners, LLC | 412.981 | 219.008 | 31/12/2023 |
0,35034 % | Walleye Capital LLC | 402.365 | 94.049 | 30/06/2024 |
0,27926 % | Adar1 Capital Management LLC | 320.727 | -135.861 | 30/06/2024 |
0,26121 % | Hooks (Corwin Dale) | 300.000 | 300.000 | 12/04/2024 |
0,24143 % | Charles Schwab Investment Management, Inc. | 277.277 | 252.773 | 30/06/2024 |
0,23535 % | BlackRock Investment Management, LLC | 270.303 | 260.752 | 30/06/2024 |
0,23106 % | Hennion & Walsh Asset Management, Inc. | 265.372 | 68.330 | 30/09/2024 |
0,22146 % | Nuveen LLC | 254.344 | 254.344 | 30/06/2024 |
0,21110 % | BlackRock Financial Management, Inc. | 242.454 | 242.454 | 30/06/2024 |
0,20356 % | Northern Trust Investments, Inc. | 233.784 | 127.331 | 30/06/2024 |
0,19952 % | Macquarie Investment Management | 229.153 | 229.153 | 30/06/2024 |
0,19806 % | Checkpoint Capital L.P. | 227.470 | 7.470 | 30/06/2024 |
0,18131 % | BNY Mellon Asset Management | 208.236 | 208.236 | 30/06/2024 |
0,14982 % | UBS Financial Services, Inc. | 172.063 | 19.303 | 30/06/2024 |
0,13867 % | Rafferty Asset Management LLC | 159.262 | 159.262 | 30/09/2024 |
0,13274 % | Goldman Sachs & Company, Inc. | 152.449 | -562.759 | 30/06/2024 |
0,13061 % | Rockefeller Capital Management | 150.000 | 0 | 30/06/2024 |
0,13060 % | Qube Research & Technologies Ltd | 149.995 | -309.146 | 30/06/2024 |
0,12956 % | Bridgeway Capital Management, LLC | 148.800 | -25.000 | 30/06/2024 |
0,11658 % | Rhumbline Advisers Ltd. Partnership | 133.895 | 133.351 | 30/06/2024 |
0,11146 % | Perfetti (Riccardo) | 128.012 | -22.681 | 22/08/2024 |
0,09980 % | SEI Investments Management Corporation | 114.619 | 114.619 | 30/06/2024 |
0,09978 % | Lerner (Teena L. Ph.D.) | 114.593 | 45.000 | 06/06/2024 |
0,09832 % | Susquehanna International Group, LLP | 112.919 | -371.966 | 30/06/2024 |
0,09657 % | Millennium Management LLC | 110.908 | -815.517 | 30/06/2024 |
0,09563 % | Jane Street Capital, L.L.C. | 109.826 | -134.786 | 30/06/2024 |
0,09404 % | Kanter (Stacy J) | 108.000 | 45.000 | 06/06/2024 |
0,09158 % | Hansard (Adam) | 105.181 | -275.034 | 10/04/2024 |
0,07761 % | Alps Advisors, Inc. | 89.131 | 89.131 | 30/06/2024 |
0,07210 % | Calamos Advisors LLC | 82.807 | 82.807 | 31/08/2024 |
0,06657 % | Citadel Advisors LLC | 76.453 | 73.344 | 30/06/2024 |
0,06579 % | Mellon Investments Corporation | 75.557 | 75.557 | 30/06/2024 |
0,06237 % | BofA Global Research (US) | 71.633 | 36.088 | 30/06/2024 |
0,05660 % | Skyler (Jay S) | 65.000 | 45.000 | 06/06/2024 |
0,05383 % | Richmond Brothers, Inc. | 61.827 | 0 | 30/06/2024 |
0,04635 % | Jump Financial, LLC | 53.235 | 9.666 | 30/06/2024 |
0,04607 % | Funtleyder (Leslie D) | 52.911 | -13.530 | 22/08/2024 |
0,04593 % | Mirae Asset Global Investments (USA) LLC | 52.752 | -1.519 | 30/09/2024 |
0,04504 % | Corebridge Financial Inc | 51.723 | 51.723 | 30/06/2024 |
0,04504 % | SunAmerica Asset Management, LLC | 51.723 | 0 | 31/07/2024 |
0,04354 % | Laurion Capital Management LP | 50.000 | -1.431.006 | 30/06/2024 |
0,03786 % | Invesco Advisers, Inc. | 43.480 | 43.480 | 30/06/2024 |
0,03773 % | Two Sigma Investments, LP | 43.338 | -111.820 | 30/06/2024 |
0,03616 % | Managed Account Advisors LLC | 41.528 | 41.528 | 30/06/2024 |
0,03568 % | JPMorgan Private Bank (United States) | 40.973 | 40.973 | 30/06/2024 |
0,03213 % | Barclays Capital Inc. | 36.899 | -24.373 | 30/06/2024 |
0,03206 % | Manulife Investment Management (North America) Limited | 36.824 | 35.539 | 30/06/2024 |
0,03073 % | Wells Fargo Bank, N.A. | 35.296 | 34.861 | 30/06/2024 |
0,02874 % | Barclays Bank PLC | 33.011 | 33.011 | 30/06/2024 |
0,02836 % | Voya Investment Management LLC | 32.568 | 32.568 | 30/06/2024 |
0,02762 % | Metropolitan Life Insurance Co. (US) | 31.724 | 31.724 | 30/06/2024 |
0,02709 % | Goldman Sachs Asset Management, L.P. | 31.111 | -208 | 30/09/2024 |
0,02671 % | T. Rowe Price International Ltd | 30.675 | 30.675 | 30/06/2024 |
0,02636 % | AllianceBernstein L.P. | 30.270 | 30.270 | 30/06/2024 |
0,02525 % | RBC Capital Markets Wealth Management | 29.000 | 29.000 | 30/06/2024 |
0,02177 % | Morgan Stanley Smith Barney LLC | 25.000 | 0 | 30/06/2024 |
0,02140 % | MetLife Investment Management, LLC | 24.578 | 24.578 | 30/06/2024 |
0,02044 % | Algert Global LLC | 23.476 | 23.476 | 30/06/2024 |
0,01846 % | New York State Common Retirement Fund | 21.200 | -17.700 | 30/09/2024 |
0,01844 % | Citi Investment Research (US) | 21.179 | -97.625 | 30/06/2024 |
0,01828 % | Axiom Asset Management | 21.000 | 0 | 30/06/2024 |
0,01783 % | Squarepoint Capital LLP | 20.478 | -173.280 | 30/06/2024 |
0,01546 % | ProShare Advisors LLC | 17.760 | -723 | 30/09/2024 |
0,01504 % | Nuveen Asset Management, LLC | 17.269 | 17.269 | 30/06/2024 |
0,01498 % | Virtus Etf Advisers LLC | 17.210 | 17.210 | 30/06/2024 |
0,01492 % | Legal & General Investment Management Ltd. | 17.137 | 17.137 | 30/06/2024 |
0,01385 % | Marathon Trading Investment Management LLC | 15.907 | -43.093 | 30/06/2024 |
0,01321 % | Northern Trust Global Investments | 15.170 | 0 | 31/08/2024 |
0,01319 % | SG Americas Securities, L.L.C. | 15.146 | -3.421 | 30/09/2024 |