11,60734 % | Celgene Corporation | 7.008.510 | 183.825 | 09/07/2020 |
8,88561 % | T. Rowe Price Associates, Inc. | 5.365.133 | 65.321 | 30/09/2021 |
8,15699 % | The Vanguard Group, Inc. | 4.925.189 | 14.836 | 30/09/2021 |
6,62471 % | Avoro Capital Advisors LLC | 4.000.000 | 1.000.000 | 30/09/2021 |
3,94211 % | BlackRock Institutional Trust Company, N.A. | 2.380.249 | -19.835 | 30/09/2021 |
3,58507 % | Farallon Capital Management, L.L.C. | 2.164.663 | -335.337 | 30/09/2021 |
3,31236 % | Darwin Global Management Ltd | 2.000.000 | 239.654 | 30/09/2021 |
3,24598 % | Fidelity Management & Research Company LLC | 1.959.920 | -677.678 | 30/09/2021 |
2,63887 % | Janus Henderson Investors | 1.593.352 | -208.470 | 30/09/2021 |
2,14143 % | Baron Capital Management, Inc. | 1.292.998 | -9.277 | 30/09/2021 |
1,96044 % | State Street Global Advisors (US) | 1.183.716 | 77.846 | 30/09/2021 |
1,74159 % | Alkeon Capital Management LLC | 1.051.571 | -2.719 | 30/09/2021 |
1,73899 % | Pentwater Capital Management LP | 1.050.000 | 1.050.000 | 30/09/2021 |
1,69135 % | BlackRock Financial Management, Inc. | 1.021.239 | -246.946 | 30/09/2021 |
1,65618 % | Invus Public Equities Advisors, LLC | 1.000.000 | -400.000 | 30/09/2021 |
1,48211 % | Westfield Capital Management Company, L.P. | 894.898 | 39.254 | 30/09/2021 |
1,37738 % | Magnetar Capital Partners LP | 831.663 | 831.663 | 30/09/2021 |
1,23731 % | Holocene Advisors, LP | 747.086 | -123.138 | 30/09/2021 |
1,18470 % | Wellington Management Company, LLP | 715.322 | -1.010.633 | 30/09/2021 |
1,11732 % | Geode Capital Management, L.L.C. | 674.636 | 4.815 | 30/09/2021 |
0,92753 % | Lord, Abbett & Co. LLC | 560.040 | 108.953 | 30/09/2021 |
0,79108 % | Norges Bank Investment Management (NBIM) | 477.655 | 0 | 31/12/2020 |
0,78904 % | Assenagon Asset Management S.A. | 476.423 | -97.379 | 30/09/2021 |
0,78250 % | Brown Advisory | 472.473 | 9.370 | 30/09/2021 |
0,76555 % | Candriam Belgium S.A. | 462.239 | -94.816 | 30/09/2021 |
0,75700 % | Eagle Asset Management, Inc. | 457.077 | -3.176 | 30/09/2021 |
0,71479 % | BlackRock Investment Management (UK) Ltd. | 431.591 | -147.243 | 30/09/2021 |
0,71383 % | Fiera Capital Corporation | 431.009 | -6.624 | 30/09/2021 |
0,70600 % | Artisan Partners Limited Partnership | 426.285 | -525.825 | 30/09/2021 |
0,67317 % | Charles Schwab Investment Management, Inc. | 406.459 | 15.493 | 30/09/2021 |
0,66447 % | ARP Americas LP | 401.208 | 401.208 | 30/09/2021 |
0,66167 % | Franklin Advisers, Inc. | 399.517 | -15.697 | 30/09/2021 |
0,65252 % | Invesco Advisers, Inc. | 393.993 | -50.505 | 30/09/2021 |
0,65005 % | TimesSquare Capital Management, LLC | 392.500 | -122.495 | 30/09/2021 |
0,64672 % | Polar Capital LLP | 390.488 | -56.692 | 30/09/2021 |
0,63632 % | Susquehanna International Group, LLP | 384.210 | 358.022 | 30/09/2021 |
0,61157 % | Goldman Sachs & Company, Inc. | 369.268 | 298.968 | 30/09/2021 |
0,58678 % | Alpine Associates Management Inc. | 354.300 | 354.300 | 30/09/2021 |
0,57882 % | Eversept Partners, LP | 349.494 | 14.449 | 30/09/2021 |
0,45300 % | Millennium Management LLC | 273.520 | 261.193 | 30/09/2021 |
0,44931 % | D. E. Shaw & Co., L.P. | 271.291 | 201.795 | 30/09/2021 |
0,41200 % | Citi Investment Research (US) | 248.768 | 198.437 | 30/09/2021 |
0,36685 % | Carmignac Gestion | 221.502 | -236.764 | 30/09/2021 |
0,35606 % | Northern Trust Investments, Inc. | 214.988 | -6.428 | 30/09/2021 |
0,33983 % | Nuveen LLC | 205.187 | -47.128 | 30/09/2021 |
0,33202 % | New York State Common Retirement Fund | 200.476 | -88.110 | 30/09/2021 |
0,33124 % | NWI Management LP | 200.000 | 0 | 30/09/2021 |
0,33027 % | Oppenheimer Asset Management Inc. | 199.417 | -324 | 30/09/2021 |
0,31216 % | UBS Asset Management (Switzerland) | 188.483 | 7.531 | 30/09/2021 |
0,28950 % | Principal Global Investors (Equity) | 174.802 | -41.687 | 30/09/2021 |
0,28754 % | Foresite Capital Management, LLC | 173.614 | 0 | 30/09/2021 |
0,26420 % | Handelsbanken Asset Management | 159.523 | 11.000 | 30/09/2021 |
0,26150 % | TD Asset Management Inc. | 157.892 | 15.151 | 30/09/2021 |
0,24090 % | AllianceBernstein L.P. | 145.454 | 117.313 | 30/09/2021 |
0,24015 % | Deerfield Management Company, L.P. | 145.000 | -74.500 | 30/09/2021 |
0,23268 % | Balyasny Asset Management LP | 140.492 | 140.492 | 30/09/2021 |
0,22457 % | Dimensional Fund Advisors, L.P. | 135.593 | 1.914 | 30/09/2021 |
0,22298 % | Martingale Asset Management, L.P. | 134.635 | -25.713 | 30/09/2021 |
0,21436 % | Westchester Capital Management, LLC | 129.432 | 129.432 | 30/09/2021 |
0,20670 % | Ensign Peak Advisors, Inc. | 124.807 | -15.141 | 30/09/2021 |
0,19990 % | Schweizerische Nationalbank | 120.700 | 600 | 30/09/2021 |
0,18750 % | Morgan Stanley & Co. LLC | 113.213 | 51.757 | 30/09/2021 |
0,18684 % | Fidelity Institutional Asset Management | 112.815 | -53.526 | 30/09/2021 |
0,18331 % | Russell Investments Trust Company | 110.683 | 23.523 | 30/09/2021 |
0,17855 % | BNP Paribas Asset Management USA, Inc. | 107.808 | -75.566 | 30/09/2021 |
0,17789 % | California Public Employees' Retirement System | 107.408 | -899 | 30/09/2021 |
0,17738 % | UBS Financial Services, Inc. | 107.102 | 30.818 | 30/09/2021 |
0,17638 % | Gabelli Funds, LLC | 106.500 | 106.500 | 30/09/2021 |
0,17124 % | Voloridge Investment Management, LLC | 103.394 | 103.394 | 30/09/2021 |
0,17072 % | Mellon Investments Corporation | 103.082 | -299.816 | 30/09/2021 |
0,16995 % | Parallax Volatility Advisers, L.P. | 102.614 | 102.614 | 30/09/2021 |
0,16380 % | Nomura Asset Management Co., Ltd. | 98.900 | 98.900 | 30/11/2020 |
0,15635 % | Loomis, Sayles & Company, L.P. | 94.406 | 94.406 | 30/09/2021 |
0,15204 % | Atika Capital Management LLC | 91.800 | 1.700 | 30/09/2021 |
0,15034 % | California State Teachers Retirement System | 90.777 | -1.047 | 30/09/2021 |
0,14867 % | Barclays Capital Inc. | 89.765 | 75.603 | 30/09/2021 |
0,14763 % | Water Island Capital, LLC | 89.140 | 89.140 | 30/09/2021 |
0,14503 % | BNY Mellon Asset Management | 87.571 | -10.251 | 30/09/2021 |
0,14076 % | Western Standard, LLC | 84.990 | 59.955 | 30/09/2021 |
0,13749 % | Wells Capital Management Inc. | 83.014 | -50.293 | 30/09/2021 |
0,13687 % | Managed Account Advisors LLC | 82.644 | -390 | 30/09/2021 |
0,13672 % | Putnam Investment Management, L.L.C. | 82.549 | -143.456 | 30/09/2021 |
0,13623 % | Principal Funds, Inc. | 82.257 | -423 | 30/09/2021 |
0,13581 % | Melqart Asset Management (UK) Limited | 82.000 | 82.000 | 30/09/2021 |
0,13249 % | Carlson Capital, L.P. | 80.000 | 80.000 | 30/09/2021 |
0,13249 % | Spring Creek Capital, LLC | 80.000 | 80.000 | 30/09/2021 |
0,13094 % | AXA Investment Managers UK Ltd. | 79.059 | -89.946 | 30/09/2021 |
0,13064 % | American Century Investment Management, Inc. | 78.882 | -28.941 | 30/09/2021 |
0,13047 % | DWS Investments UK Limited | 78.778 | 75 | 30/09/2021 |
0,12871 % | Weiss Multi-Strategy Advisers LLC | 77.714 | 39.671 | 30/09/2021 |
0,11943 % | Parametric Portfolio Associates LLC | 72.110 | 11.326 | 30/09/2021 |
0,11913 % | Cutler Group, LP | 71.931 | 70.893 | 30/09/2021 |
0,11865 % | J.P. Morgan Securities LLC | 71.642 | 70.667 | 30/09/2021 |
0,11758 % | QVT Financial LP | 70.996 | -30.400 | 30/09/2021 |
0,11492 % | Comerica, Inc. | 69.387 | 20.416 | 30/06/2021 |
0,11431 % | RBC Capital Markets Wealth Management | 69.018 | -1.130 | 30/09/2021 |
0,11243 % | Granahan Investment Management, Inc. | 67.888 | -12.420 | 30/09/2021 |
0,11107 % | DWS Investment GmbH | 67.064 | 0 | 30/09/2021 |
0,10851 % | SEB Investment Management AB | 65.516 | -26.971 | 30/09/2021 |
0,10796 % | Florida State Board of Administration | 65.185 | -658 | 30/09/2021 |