10,00844 % | RTW Investments L.P. | 7 582 396 | 60 537 | 2021. 09. 30. |
7,14650 % | Eli Lilly and Company | 5 414 185 | 0 | 2021. 04. 01. |
5,97480 % | BlackRock Institutional Trust Company, N.A. | 4 526 507 | 21 658 | 2021. 09. 30. |
5,12959 % | State Street Global Advisors (US) | 3 886 181 | 1 297 119 | 2021. 09. 30. |
4,89336 % | The Vanguard Group, Inc. | 3 707 210 | 86 857 | 2021. 09. 30. |
4,06578 % | Bain Capital Life Sciences Investors, LLC | 3 080 237 | 0 | 2021. 09. 30. |
3,54091 % | T. Rowe Price Associates, Inc. | 2 682 596 | 699 671 | 2021. 09. 30. |
3,24260 % | Aquilo Capital Management, LLC | 2 456 595 | 643 203 | 2021. 09. 30. |
2,12232 % | Morgan Stanley & Co. LLC | 1 607 870 | 626 309 | 2021. 09. 30. |
1,78465 % | Woodline Partners LP | 1 352 048 | 351 723 | 2021. 09. 30. |
1,78268 % | Assenagon Asset Management S.A. | 1 350 558 | 780 152 | 2021. 09. 30. |
1,76962 % | Two Sigma Investments, LP | 1 340 661 | 715 555 | 2021. 09. 30. |
1,72984 % | Maverick Capital, Ltd. | 1 310 530 | 2454 | 2021. 09. 30. |
1,71512 % | Polar Capital LLP | 1 299 372 | 214 559 | 2021. 09. 30. |
1,70572 % | Commodore Capital LP | 1 292 251 | 1 292 251 | 2021. 09. 30. |
1,68052 % | JPMorgan Asset Management U.K. Limited | 1 273 160 | 208 538 | 2021. 09. 30. |
1,64970 % | EcoR1 Capital, LLC | 1 249 812 | 1 249 812 | 2021. 09. 30. |
1,57164 % | Geode Capital Management, L.L.C. | 1 190 676 | 2981 | 2021. 09. 30. |
1,45364 % | UBS Financial Services, Inc. | 1 101 275 | -234 545 | 2021. 09. 30. |
1,12951 % | Palo Alto Investors LP | 855 713 | 523 000 | 2021. 09. 30. |
1,12496 % | BlackRock Financial Management, Inc. | 852 273 | -5754 | 2021. 09. 30. |
1,06519 % | Pictet Asset Management Ltd. | 806 987 | 803 987 | 2021. 09. 30. |
1,05596 % | Great Point Partners, LLC | 799 999 | 799 999 | 2021. 09. 30. |
0,93674 % | Eagle Asset Management, Inc. | 709 674 | -608 373 | 2021. 09. 30. |
0,92569 % | Banque Lombard Odier & Cie SA | 701 305 | 65 294 | 2021. 09. 30. |
0,92397 % | Invus Public Equities Advisors, LLC | 700 000 | -100 000 | 2021. 09. 30. |
0,87741 % | Northern Trust Investments, Inc. | 664 723 | -6796 | 2021. 09. 30. |
0,83870 % | Point72 Asset Management, L.P. | 635 400 | -85 000 | 2021. 09. 30. |
0,78114 % | Marshall Wace LLP | 591 790 | 591 790 | 2021. 09. 30. |
0,77542 % | Dafna Capital Management, LLC | 587 456 | 76 700 | 2021. 09. 30. |
0,72377 % | Goldman Sachs & Company, Inc. | 548 327 | 15 627 | 2021. 09. 30. |
0,70433 % | Wellington Management Company, LLP | 533 604 | -2 765 749 | 2021. 09. 30. |
0,68277 % | Charles Schwab Investment Management, Inc. | 517 263 | 17 340 | 2021. 09. 30. |
0,67795 % | Fidelity Management & Research Company LLC | 513 612 | -105 100 | 2021. 09. 30. |
0,54440 % | Nuveen LLC | 412 439 | 8187 | 2021. 09. 30. |
0,53660 % | Eagle Health Investments LP | 406 525 | 245 400 | 2021. 09. 30. |
0,52852 % | Invesco Capital Management LLC | 400 406 | 234 317 | 2021. 09. 30. |
0,51926 % | Candriam Belgium S.A. | 393 390 | -24 855 | 2021. 09. 30. |
0,47680 % | Millennium Management LLC | 361 222 | 25 736 | 2021. 09. 30. |
0,43429 % | Voloridge Investment Management, LLC | 329 016 | 266 797 | 2021. 09. 30. |
0,41788 % | Medical Strategy GmbH | 316 588 | -58 160 | 2021. 06. 30. |
0,36688 % | Balyasny Asset Management LP | 277 949 | 191 393 | 2021. 09. 30. |
0,34477 % | Citadel Advisors LLC | 261 200 | -72 328 | 2021. 09. 30. |
0,33028 % | Goldman Sachs Asset Management, L.P. | 250 217 | 172 463 | 2021. 09. 30. |
0,30710 % | UBS Asset Management (Americas), Inc. | 232 658 | -5076 | 2021. 09. 30. |
0,29988 % | Federated Hermes MDTA LLC | 227 187 | -167 114 | 2021. 09. 30. |
0,29463 % | Emerald Advisers LLC | 223 213 | -734 271 | 2021. 09. 30. |
0,29182 % | APG Asset Management N.V. | 221 083 | 221 083 | 2020. 06. 30. |
0,28586 % | Carson Wealth Management Group | 216 565 | 71 374 | 2021. 06. 30. |
0,28085 % | BlackRock Investment Management, LLC | 212 773 | -19 851 | 2021. 09. 30. |
0,27910 % | AXA Investment Managers UK Ltd. | 211 448 | -31 320 | 2021. 09. 30. |
0,27678 % | Parkman Healthcare Partners LLC | 209 686 | -95 000 | 2021. 09. 30. |
0,27303 % | Russell Investments Trust Company | 206 845 | 28 079 | 2021. 09. 30. |
0,26984 % | Mirae Asset Global Investments (USA) LLC | 204 430 | 39 179 | 2021. 09. 30. |
0,26885 % | Schonfeld Strategic Advisors LLC | 203 680 | 158 795 | 2021. 09. 30. |
0,23826 % | Silvercrest Asset Management Group LLC | 180 502 | 33 686 | 2021. 09. 30. |
0,22114 % | Connor, Clark & Lunn Investment Management Ltd. | 167 538 | 79 527 | 2021. 09. 30. |
0,21626 % | BNY Mellon Asset Management | 163 841 | 1444 | 2021. 09. 30. |
0,20229 % | JP Morgan Asset Management | 153 256 | -36 590 | 2021. 09. 30. |
0,20182 % | Schweizerische Nationalbank | 152 900 | 4000 | 2021. 09. 30. |
0,19943 % | Voya Investment Management LLC | 151 085 | -3274 | 2021. 09. 30. |
0,19860 % | AllianceBernstein L.P. | 150 459 | -35 398 | 2021. 09. 30. |
0,18953 % | Rafferty Asset Management LLC | 143 589 | 73 769 | 2021. 09. 30. |
0,17766 % | First Trust Advisors L.P. | 134 599 | 44 222 | 2021. 09. 30. |
0,17305 % | Renaissance Technologies LLC | 131 100 | -100 | 2021. 09. 30. |
0,16935 % | Bank J. Safra Sarasin AG (Asset Management) | 128 296 | 28 148 | 2021. 09. 30. |
0,16821 % | Citi Investment Research (US) | 127 437 | -14 431 | 2021. 09. 30. |
0,15958 % | Alphacrest Capital Management LLC | 120 900 | 120 900 | 2021. 09. 30. |
0,15819 % | Duality Group | 119 842 | 119 842 | 2021. 09. 30. |
0,15667 % | Mellon Investments Corporation | 118 692 | 20 761 | 2021. 09. 30. |
0,15328 % | Morgan Stanley Investment Management Inc. (US) | 116 123 | 1157 | 2021. 09. 30. |
0,14845 % | JPMorgan Private Bank (United States) | 112 466 | -4894 | 2021. 09. 30. |
0,14652 % | Susquehanna International Group, LLP | 111 005 | -41 688 | 2021. 09. 30. |
0,14520 % | Hudson Bay Capital Management LP | 110 000 | 25 024 | 2021. 09. 30. |
0,13651 % | D. E. Shaw & Co., L.P. | 103 422 | 103 422 | 2021. 09. 30. |
0,12576 % | Alps Advisors, Inc. | 95 276 | 86 586 | 2021. 09. 30. |
0,12566 % | PanAgora Asset Management Inc. | 95 203 | 57 365 | 2021. 09. 30. |
0,12449 % | California State Teachers Retirement System | 94 311 | -642 | 2021. 09. 30. |
0,12262 % | Evolutionary Tree Capital Management, LLC | 92 898 | -48 426 | 2021. 09. 30. |
0,12130 % | Lyxor Asset Management | 91 895 | -450 | 2021. 10. 31. |
0,12108 % | AQR Capital Management, LLC | 91 733 | 52 741 | 2021. 09. 30. |
0,11855 % | Arctic Fund Management AS | 89 814 | -67 000 | 2021. 09. 30. |
0,11720 % | BlackRock Advisors (UK) Limited | 88 793 | 2580 | 2021. 10. 31. |
0,11708 % | State of Wisconsin Investment Board | 88 700 | 0 | 2021. 09. 30. |
0,10733 % | BofA Global Research (US) | 81 313 | -66 797 | 2021. 09. 30. |
0,10486 % | Foord Asset Management (Pty) Limited | 79 445 | 79 445 | 2021. 06. 30. |
0,10359 % | BlackRock Asset Management Ireland Limited | 78 478 | -7240 | 2021. 09. 30. |
0,10322 % | Deka Investment GmbH | 78 200 | 78 200 | 2020. 12. 31. |
0,10288 % | Rhumbline Advisers Ltd. Partnership | 77 944 | -1119 | 2021. 09. 30. |
0,10123 % | Northern Trust Global Investments | 76 689 | -768 | 2021. 09. 30. |
0,10037 % | Parametric Portfolio Associates LLC | 76 037 | -9834 | 2021. 09. 30. |
0,09792 % | TD Asset Management Inc. | 74 186 | 0 | 2021. 09. 30. |
0,09556 % | Foord Asset Management (Singapore) Pte. Ltd. | 72 399 | 72 399 | 2021. 06. 30. |
0,09522 % | UBS Asset Management (Switzerland) | 72 137 | -5674 | 2021. 09. 30. |
0,09244 % | Advisors Asset Management, Inc. | 70 029 | 22 425 | 2021. 09. 30. |
0,09073 % | BlackRock Investment Management (UK) Ltd. | 68 736 | 5581 | 2021. 09. 30. |
0,08787 % | Credit Suisse Asset Management | 66 572 | 129 | 2021. 09. 30. |
0,08678 % | Manchester Capital Management LLC | 65 742 | 0 | 2021. 09. 30. |
0,07971 % | Legal & General Investment Management Ltd. | 60 386 | 44 332 | 2021. 09. 30. |
0,07787 % | Cubist Systematic Strategies, LLC | 58 993 | 44 923 | 2021. 09. 30. |