7.05349 % | BlackRock Institutional Trust Company, N.A. | 3,484,424 | -13,509 | 30.9.2021 |
5.60604 % | OrbiMed Advisors, LLC | 2,769,383 | 0 | 30.9.2021 |
5.23893 % | The Vanguard Group, Inc. | 2,588,032 | -15,256 | 30.9.2021 |
4.21872 % | Soleus Capital Management, L.P. | 2,084,050 | 2,084,050 | 30.9.2021 |
3.86671 % | Clearline Capital LP | 1,910,153 | -213,546 | 30.9.2021 |
2.84083 % | Novo Holdings A/S | 1,403,370 | 0 | 30.9.2021 |
2.49634 % | Granahan Investment Management, Inc. | 1,233,194 | -180,109 | 30.9.2021 |
2.33476 % | State Street Global Advisors (US) | 1,153,373 | -2,823,331 | 30.9.2021 |
2.14189 % | Geode Capital Management, L.L.C. | 1,058,094 | 226,660 | 30.9.2021 |
2.02429 % | Versant Ventures | 1,000,000 | 0 | 30.9.2021 |
1.89576 % | TPG Capital, L.P. | 936,507 | 0 | 30.9.2021 |
1.88536 % | Clayman (Michael D) | 931,367 | -13,859 | 19.7.2021 |
1.57480 % | Millennium Management LLC | 777,952 | 202,906 | 30.9.2021 |
1.47409 % | Paradigm Capital Management, Inc. | 728,200 | 628,200 | 30.9.2021 |
1.36682 % | JPMorgan Asset Management U.K. Limited | 675,209 | 105,063 | 30.9.2021 |
1.22322 % | Raymond James Financial Services Advisors, Inc. | 604,271 | 178,506 | 30.9.2021 |
1.06948 % | Acadian Asset Management LLC | 528,324 | 235,514 | 30.9.2021 |
1.03082 % | Jacobs Levy Equity Management, Inc. | 509,225 | -434,540 | 30.9.2021 |
1.02591 % | Two Sigma Investments, LP | 506,800 | -730,929 | 30.9.2021 |
1.01989 % | Victory Capital Management Inc. | 503,828 | -18,000 | 30.9.2021 |
1.01618 % | Bessemer Trust Company, N.A. (US) | 501,994 | 35,748 | 30.4.2021 |
0.91641 % | Northern Trust Investments, Inc. | 452,707 | 2,568 | 30.9.2021 |
0.90021 % | Raymond James & Associates, Inc. | 444,705 | 80,529 | 30.9.2021 |
0.89849 % | BlackRock Financial Management, Inc. | 443,853 | 7,248 | 30.9.2021 |
0.88789 % | Fred Alger Management, LLC | 438,619 | 175,975 | 30.9.2021 |
0.77871 % | Moody National Bank | 384,684 | 74 | 30.9.2021 |
0.74586 % | Zazove Associates, LLC | 368,456 | 78,466 | 30.9.2021 |
0.72972 % | Morgan Stanley & Co. LLC | 360,484 | -119,994 | 30.9.2021 |
0.68067 % | American National Insurance Co | 336,250 | -365 | 30.9.2021 |
0.63516 % | Easterly Investment Partners LLC | 313,770 | 313,770 | 30.9.2021 |
0.63467 % | Snow Capital Management, L.P. | 313,525 | 150 | 30.6.2021 |
0.53963 % | Citadel Advisors LLC | 266,575 | 266,575 | 30.9.2021 |
0.49741 % | Nuveen LLC | 245,719 | 28,953 | 30.9.2021 |
0.42741 % | Gagnon Securities LLC | 211,141 | 2,111 | 30.9.2021 |
0.38891 % | RBC Capital Markets Wealth Management | 192,120 | 2,954 | 30.9.2021 |
0.36660 % | HRT Financial LP | 181,099 | 181,099 | 30.9.2021 |
0.36013 % | Marshall Wace LLP | 177,903 | 177,903 | 30.9.2021 |
0.34716 % | Cubist Systematic Strategies, LLC | 171,497 | 90,961 | 30.9.2021 |
0.32600 % | BMO Asset Management U.S. | 161,045 | 161,045 | 30.9.2021 |
0.32469 % | William Blair & Company, L.L.C. (Research) | 160,399 | 10,299 | 30.9.2021 |
0.32209 % | BlackRock Investment Management, LLC | 159,114 | -15,414 | 30.9.2021 |
0.32156 % | American Financial Group, Inc. | 158,850 | 0 | 30.9.2021 |
0.31066 % | Squarepoint Capital LLP | 153,465 | 55,793 | 30.9.2021 |
0.30648 % | Willwerth (Christina) | 151,402 | -3,945 | 19.7.2021 |
0.28495 % | Susquehanna International Group, LLP | 140,764 | -32,294 | 30.9.2021 |
0.28179 % | Wentworth (Kerry A) | 139,202 | -3,944 | 19.7.2021 |
0.27263 % | Wells Fargo Advisors | 134,678 | 30,276 | 30.9.2021 |
0.26974 % | JP Morgan Asset Management | 133,253 | -9,939 | 30.9.2021 |
0.26573 % | New York State Common Retirement Fund | 131,271 | -61,555 | 30.9.2021 |
0.25449 % | Arkowitz (David A.) | 125,719 | -2,229 | 10.5.2021 |
0.24470 % | Charles Schwab Investment Management, Inc. | 120,880 | -195,445 | 30.9.2021 |
0.24138 % | SG Americas Securities, L.L.C. | 119,243 | 85,462 | 30.9.2021 |
0.24132 % | Invesco Capital Management LLC | 119,210 | 25,715 | 30.9.2021 |
0.23975 % | AQR Capital Management, LLC | 118,437 | 103,995 | 30.9.2021 |
0.23191 % | ExodusPoint Capital Management, LP | 114,564 | 87,417 | 30.9.2021 |
0.21821 % | BNY Mellon Asset Management | 107,797 | -1,745 | 30.9.2021 |
0.21106 % | Ohio Public Employees Retirement System | 104,262 | 0 | 30.9.2021 |
0.21044 % | Layman (Melissa) | 103,956 | 15,580 | 15.3.2021 |
0.20985 % | Muzikant (Adam) | 103,666 | -1,870 | 19.7.2021 |
0.20862 % | BlackRock Investment Management (UK) Ltd. | 103,056 | 18,628 | 30.9.2021 |
0.20354 % | Barclays Bank PLC | 100,547 | 17,925 | 30.9.2021 |
0.20243 % | CM Management, LLC | 100,000 | 25,000 | 30.9.2021 |
0.19291 % | Parametric Portfolio Associates LLC | 95,296 | 59,522 | 30.9.2021 |
0.19105 % | Colella (Samuel D) | 94,381 | 4,500 | 24.6.2021 |
0.18543 % | Trexquant Investment LP | 91,600 | 67,299 | 30.9.2021 |
0.18279 % | Levine Mark S | 90,299 | -3,945 | 19.7.2021 |
0.17816 % | Schweizerische Nationalbank | 88,011 | 0 | 30.9.2021 |
0.15335 % | M & G Investment Management Ltd. | 75,753 | -52,641 | 30.9.2021 |
0.15069 % | GAM Investment Management (Switzerland) AG | 74,442 | -26,753 | 30.9.2021 |
0.15069 % | GAM Capital Management (Switzerland) AG | 74,442 | -60,342 | 30.9.2021 |
0.14778 % | BofA Global Research (US) | 73,004 | -115,837 | 30.9.2021 |
0.14433 % | Belvedere Trading, LLC | 71,300 | 71,300 | 30.9.2021 |
0.14364 % | Commonwealth Financial Network | 70,956 | -2,229 | 30.9.2021 |
0.14147 % | Brandywine Global Investment Management, LLC | 69,885 | -614 | 30.9.2021 |
0.12669 % | Goldman Sachs & Company, Inc. | 62,583 | -769,024 | 30.9.2021 |
0.12605 % | Golden State Equity Partners, L.L.C | 62,270 | 41,670 | 30.9.2021 |
0.12551 % | Birch Grove Capital LP | 62,000 | 0 | 30.9.2021 |
0.12368 % | Kelley (Scott D) | 61,099 | 30,000 | 1.3.2021 |
0.11877 % | California State Teachers Retirement System | 58,674 | -7,726 | 30.9.2021 |
0.11862 % | AllianceBernstein L.P. | 58,600 | 0 | 30.9.2021 |
0.11429 % | BlackRock Advisors (UK) Limited | 56,459 | 1,847 | 31.10.2021 |
0.10693 % | Rhumbline Advisers Ltd. Partnership | 52,824 | 1,884 | 30.9.2021 |
0.10474 % | Credit Suisse Asset Management | 51,743 | 5,108 | 30.9.2021 |
0.10312 % | BlackRock Asset Management Ireland Limited | 50,943 | -6,377 | 30.9.2021 |
0.10121 % | L&S Advisors Inc. | 50,000 | 50,000 | 30.9.2021 |
0.10064 % | Northern Trust Global Investments | 49,715 | -2,429 | 30.9.2021 |
0.09923 % | Florida State Board of Administration | 49,022 | 24,780 | 30.9.2021 |
0.09626 % | American National Registered Investment Advisor, Inc. | 47,550 | -145 | 30.9.2021 |
0.09370 % | EMC Capital Management LLC | 46,287 | 0 | 30.9.2021 |
0.08433 % | Goldman Sachs Asset Management, L.P. | 41,661 | -240,877 | 30.9.2021 |
0.08003 % | Mellon Investments Corporation | 39,533 | 10,778 | 30.9.2021 |
0.07863 % | First Eagle Investment Management, L.L.C. | 38,841 | 30,509 | 30.9.2021 |
0.07692 % | Prelude Capital Management, LLC | 38,000 | 1,700 | 30.9.2021 |
0.07689 % | Russell Investments Trust Company | 37,985 | -1,386 | 30.9.2021 |
0.07470 % | Ergoteles Capital | 36,900 | 36,900 | 30.9.2021 |
0.07373 % | UBS Asset Management (Switzerland) | 36,425 | 0 | 30.9.2021 |
0.07151 % | Mahaffy (Patrick J) | 35,324 | 4,500 | 24.6.2021 |
0.07105 % | Driscoll (Frederick W.) | 35,097 | 35,097 | 1.6.2021 |
0.07085 % | Bellatrix Asset Management | 35,000 | 0 | 30.6.2021 |
0.06974 % | T. Rowe Price Associates, Inc. | 34,451 | 15,393 | 30.9.2021 |