19.75881 % | BVF Partners L.P. | 8,748,629 | 0 | 9.4.2025 |
9.71157 % | Tang Capital Management, LLC | 4,300,000 | 0 | 31.3.2025 |
9.53438 % | BML Capital Management LLC | 4,221,546 | 0 | 24.4.2025 |
9.48573 % | Morgan Stanley & Co. LLC | 4,200,007 | 10,759 | 31.3.2025 |
5.10879 % | Soleus Capital Management, L.P. | 2,262,026 | 0 | 23.4.2025 |
4.99129 % | Opaleye Management Inc. | 2,209,998 | 0 | 31.3.2025 |
3.78299 % | Pfizer Inc | 1,675,000 | 0 | 31.3.2025 |
2.37226 % | Altium Capital Management LP | 1,050,369 | -377,631 | 31.3.2025 |
1.77158 % | Berger (Franklin Milan) | 784,404 | 0 | 8.1.2025 |
1.57704 % | BofA Global Research (US) | 698,268 | -114,042 | 31.3.2025 |
1.28575 % | Aldebaran Capital, LLC | 569,294 | 171,771 | 31.3.2025 |
1.25397 % | Two Sigma Investments, LP | 555,220 | 245,473 | 31.3.2025 |
1.12925 % | Aguja Capital GmbH | 500,000 | 0 | 31.1.2025 |
0.53165 % | BNP Paribas Securities Corp. North America | 235,401 | 70,806 | 31.3.2025 |
0.48514 % | Medical Strategy GmbH | 214,804 | -54,500 | 30.11.2024 |
0.41479 % | DLD Asset Management, LP | 183,658 | 183,658 | 31.3.2025 |
0.37232 % | J.P. Morgan Securities LLC | 164,854 | 164,854 | 31.3.2025 |
0.24937 % | Deuterium Capital Management, LLC | 110,412 | 110,412 | 31.3.2025 |
0.22481 % | Morgan Stanley Smith Barney LLC | 99,540 | 93,140 | 31.3.2025 |
0.18548 % | Citadel Advisors LLC | 82,123 | -76,918 | 31.3.2025 |
0.14853 % | Parkinson (David Ross M.D.) | 65,765 | 0 | 8.1.2025 |
0.12468 % | Magnus Financial Group LLC | 55,206 | 0 | 31.3.2025 |
0.11676 % | Glickman (Richard M) | 51,700 | -8,460 | 8.1.2025 |
0.10473 % | American Century Investment Management, Inc. | 46,373 | 0 | 31.3.2025 |
0.10429 % | Avantis Investors | 46,176 | 26,132 | 31.3.2024 |
0.07587 % | Wood (David Sidney) | 33,593 | 250 | 8.1.2025 |
0.07159 % | Lepercq de Neuflize Asset Management, LLC | 31,700 | 1,500 | 31.3.2025 |
0.06821 % | Lepercq Corporation Management Ltd | 30,200 | 30,200 | 31.12.2024 |
0.06776 % | Requadt (Scott) | 30,002 | 0 | 8.1.2025 |
0.06066 % | Geode Capital Management, L.L.C. | 26,858 | 0 | 31.3.2025 |
0.05563 % | Shay Capital LLC | 24,631 | 24,631 | 31.3.2025 |
0.05332 % | UBS Financial Services, Inc. | 23,608 | -72,006 | 31.3.2025 |
0.05159 % | Schonfeld Strategic Advisors LLC | 22,843 | -26,000 | 31.3.2025 |
0.05156 % | XTX Markets LLC | 22,829 | -14,697 | 31.3.2025 |
0.04770 % | Group One Trading, L.P. | 21,118 | -15,230 | 31.3.2025 |
0.03636 % | Tucker Asset Management LLC | 16,097 | 16,097 | 31.3.2024 |
0.03214 % | Martin (John Alexander) | 14,229 | 0 | 8.1.2025 |
0.03188 % | Cubist Systematic Strategies, LLC | 14,115 | -12,172 | 31.3.2025 |
0.01756 % | Virsik (Peter) | 7,776 | 0 | 8.1.2025 |
0.01355 % | Osaic Holdings, Inc. | 6,000 | 0 | 31.3.2025 |
0.01316 % | BlackRock Financial Management, Inc. | 5,826 | 0 | 31.3.2025 |
0.01157 % | Cesano (Alessandra) | 5,124 | 0 | 8.1.2025 |
0.00915 % | Desjardins Securities Inc. | 4,050 | 0 | 31.3.2025 |
0.00833 % | Truvestments Capital LLC | 3,688 | -253 | 31.3.2025 |
0.00651 % | Thorell (Marella) | 2,881 | 0 | 8.1.2025 |
0.00565 % | CIBC Private Wealth Management | 2,500 | 0 | 31.3.2025 |
0.00282 % | BlackRock Institutional Trust Company, N.A. | 1,248 | 0 | 31.3.2025 |
0.00203 % | TD Waterhouse Canada, Inc. | 900 | 0 | 31.3.2025 |
0.00152 % | RBC Dominion Securities, Inc. | 675 | -100 | 31.3.2025 |
0.00136 % | Laurel Wealth Advisors, LLC | 600 | 0 | 31.3.2025 |
0.00080 % | Barclays Bank PLC | 355 | 0 | 31.3.2025 |
0.00050 % | Morgan Stanley Canada Limited | 221 | 0 | 31.3.2025 |
0.00032 % | RBC Capital Markets Wealth Management | 142 | -1 | 31.3.2025 |
0.00005 % | J.P. Morgan Securities plc | 21 | 0 | 31.3.2025 |
0 % | Squarepoint Capital LLP | 0 | -14,525 | 31.3.2025 |
0 % | Simplex Trading, LLC | 0 | -5,162 | 31.12.2024 |
0 % | Blackstone Alternative Investment Advisors LLC | 0 | -800 | 31.12.2023 |
0 % | Hunting Hill Global Capital, LLC | 0 | -10,000 | 31.12.2023 |
0 % | Rock Springs Capital Management LP | 0 | -677,005 | 31.12.2024 |
0 % | Rhenman & Partners Asset Management AB | 0 | -804,649 | 31.12.2024 |
0 % | RTW Investments L.P. | 0 | -1,113,002 | 31.3.2025 |
0 % | Jane Street Capital, L.L.C. | 0 | -45,810 | 31.3.2025 |
0 % | Susquehanna International Group, LLP | 0 | -17,704 | 31.3.2025 |
0 % | PFM Health Sciences, LP | 0 | -2,742,936 | 31.12.2024 |
0 % | Connective Capital Management, LLC | 0 | -84,578 | 31.12.2023 |
0 % | Prelude Capital Management, LLC | 0 | -25,000 | 31.3.2025 |
0 % | Tower Research Capital LLC | 0 | -27 | 30.9.2023 |
0 % | Northern Trust Global Investments | 0 | -4,661 | 30.9.2023 |
0 % | TD Securities, Inc. | 0 | -48 | 30.9.2024 |
0 % | RBC Capital Partners | 0 | -537 | 30.9.2024 |
0 % | Bellevue Asset Management AG | 0 | -7,879,583 | 1.11.2024 |
0 % | Adage Capital Management, L.P. | 0 | -1,474,165 | 31.12.2024 |
0 % | Marshall Wace LLP | 0 | -181,217 | 31.3.2025 |
0 % | Millennium Management LLC | 0 | -14,052 | 30.6.2024 |
0 % | Renaissance Technologies LLC | 0 | -24,234 | 31.3.2024 |
0 % | OrbiMed Advisors, LLC | 0 | -842,366 | 31.12.2023 |
0 % | D. E. Shaw & Co., L.P. | 0 | -62,955 | 31.12.2024 |
0 % | Acadian Asset Management LLC | 0 | -15,687 | 31.3.2025 |
0 % | Driehaus Capital Management, LLC | 0 | -28,300 | 30.9.2023 |
0 % | Janus Henderson Investors | 0 | -1,006,202 | 30.9.2024 |
0 % | CIBC World Markets Inc. | 0 | -73,587 | 31.12.2024 |
0 % | State Street Global Advisors (US) | 0 | -24,414 | 30.9.2023 |
0 % | Northern Trust Investments, Inc. | 0 | -7,828 | 30.9.2023 |
0 % | Kennedy Capital Management LLC | 0 | -41,092 | 31.12.2024 |
0 % | Parametric Portfolio Associates LLC | 0 | -194 | 31.12.2024 |
0 % | 49 Financial | 0 | -11,172 | 31.3.2025 |
0 % | Entrypoint Capital LLC | 0 | -4,420 | 30.6.2024 |
0 % | Privium Fund Management (UK) Ltd | 0 | -20,032 | 31.3.2024 |
0 % | GTS Securities LLC | 0 | -16,700 | 31.3.2025 |
0 % | Vazirani Asset Management LLC | 0 | -50,000 | 31.3.2025 |
0 % | Parkman Healthcare Partners LLC | 0 | -345,902 | 31.12.2024 |
0 % | FNY Investment Advisers LLC | 0 | -25,000 | 31.3.2025 |