6.20612 % | BlackRock Institutional Trust Company, N.A. | 9,247,121 | 398,538 | |
5.13885 % | The Vanguard Group, Inc. | 7,656,890 | 50,648 | |
3.43178 % | Caxton Associates LP | 5,113,348 | 0 | |
3.24196 % | MPM BioImpact LLC | 4,830,526 | 664,030 | |
2.18700 % | State Street Global Advisors (US) | 3,258,633 | 43,617 | |
2.17475 % | Geode Capital Management, L.L.C. | 3,240,379 | 195,015 | |
2.09407 % | Rosalind Advisors, Inc. | 3,120,170 | 300,000 | |
1.13861 % | Millennium Management LLC | 1,696,524 | 771 | |
1.07514 % | McCulloch (Kevin) | 1,601,953 | 1,601,953 | |
0.98381 % | CenterBook Partners LP | 1,465,875 | -77,998 | |
0.90714 % | Renaissance Technologies LLC | 1,351,640 | 342,300 | |
0.89745 % | Nuveen LLC | 1,337,207 | -247,890 | |
0.80072 % | AQR Capital Management, LLC | 1,193,080 | 52,074 | |
0.77971 % | Edick (Paul Raymond) | 1,161,772 | -1,211,439 | |
0.70241 % | Redmile Group, LLC | 1,046,587 | 0 | |
0.68458 % | Northern Trust Investments, Inc. | 1,020,022 | -51,650 | |
0.64287 % | Medical Strategy GmbH | 957,877 | -1,767,529 | |
0.60447 % | Morgan Stanley Smith Barney LLC | 900,658 | 626,680 | |
0.56945 % | Johnson (John H.) | 848,483 | 50,000 | |
0.55034 % | Knott Partners Management, LLC | 820,000 | 220,000 | |
0.53939 % | Shannon John Patrick Jr | 803,691 | 250,000 | |
0.48961 % | Prestrelski (Steven) | 729,524 | 150,000 | |
0.43416 % | Morgan Stanley & Co. LLC | 646,891 | -335,806 | |
0.43065 % | BofA Global Research (US) | 641,666 | 13,619 | |
0.42701 % | Lazard Asset Management, L.L.C. | 636,244 | 215,757 | |
0.40649 % | GSA Capital Partners LLP | 605,663 | 593,952 | |
0.40118 % | BlackRock Financial Management, Inc. | 597,762 | -57,727 | |
0.39737 % | Invenomic Capital Management LP | 592,078 | -12,434 | |
0.38469 % | Tudor Investment Corporation | 573,186 | 0 | |
0.34767 % | D. E. Shaw & Co., L.P. | 518,024 | -188,987 | |
0.28329 % | Wellington Management Company, LLP | 422,109 | 25,164 | |
0.27153 % | Charles Schwab Investment Management, Inc. | 404,582 | 38,289 | |
0.24989 % | Pieper (Steven) | 372,338 | -14,767 | |
0.24563 % | BlackRock Investment Management, LLC | 365,993 | 32,887 | |
0.23328 % | Jane Street Capital, L.L.C. | 347,592 | 117,634 | |
0.22553 % | Schonfeld Strategic Advisors LLC | 336,047 | 45,549 | |
0.22315 % | BNY Mellon Asset Management | 332,500 | 40,940 | |
0.21217 % | Hecht (Beth P) | 316,129 | -501,123 | |
0.20134 % | Alpine Global Management, LLC | 300,000 | 0 | |
0.19888 % | IHT Wealth Management, LLC | 296,335 | -2,032 | |
0.16648 % | J.P. Morgan Securities LLC | 248,048 | -42,343 | |
0.14926 % | Goldman Sachs & Company, Inc. | 222,400 | 70,727 | |
0.14759 % | Columbia Threadneedle Investments (US) | 219,906 | -733,330 | |
0.12769 % | Brown Advisory | 190,255 | 0 | |
0.12750 % | Rhumbline Advisers Ltd. Partnership | 189,970 | 12,332 | |
0.12580 % | Commonwealth Financial Network | 187,443 | 440 | |
0.11795 % | Diversified Trust Company | 175,739 | 0 | |
0.11596 % | Thompson, Siegel & Walmsley LLC | 172,784 | -17,216 | |
0.11593 % | Barclays Bank PLC | 172,743 | -32,186 | |
0.11472 % | Hamblin Watsa Investment Counsel Ltd. | 170,937 | 19,542 | |
0.09914 % | AllianceBernstein L.P. | 147,720 | 67,300 | |
0.08790 % | T. Rowe Price International Ltd | 130,968 | 5,333 | |
0.08542 % | Sherman (Jeffrey W) | 127,280 | 50,000 | |
0.08164 % | Kong (Garheng) | 121,644 | 50,000 | |
0.07949 % | Cetera Investment Advisers LLC | 118,443 | -122 | |
0.07892 % | Cetera Advisor Networks LLC | 117,585 | 595 | |
0.07144 % | UBS Financial Services, Inc. | 106,449 | -88,974 | |
0.07066 % | Johnson (Kenneth Erland) | 105,290 | -261,696 | |
0.06767 % | Parkman Healthcare Partners LLC | 100,830 | 154 | |
0.06447 % | Mellon Investments Corporation | 96,054 | 39,075 | |
0.06259 % | Goldman Sachs Asset Management, L.P. | 93,264 | -6,511 | |
0.05891 % | State Street Global Advisors Ireland Limited | 87,770 | -319 | |
0.05849 % | Northern Trust Global Investments | 87,147 | -736 | |
0.05546 % | MetLife Investment Management, LLC | 82,638 | 24,546 | |
0.05512 % | BlackRock Asset Management Ireland Limited | 82,133 | 1,551 | |
0.05512 % | BlackRock Advisors (UK) Limited | 82,133 | 1,813 | |
0.05480 % | Schmid (John P) | 81,659 | 50,000 | |
0.05397 % | OrbiMed Advisors, LLC | 80,420 | 0 | |
0.05277 % | Principal Global Investors (Equity) | 78,626 | -10,992 | |
0.05265 % | Sigma Planning Corporation | 78,450 | 1,900 | |
0.05257 % | Fairley (Ricki Louise) | 78,334 | 50,000 | |
0.05063 % | Corebridge Financial Inc | 75,441 | 75,441 | |
0.05012 % | LPL Financial LLC | 74,677 | 35,700 | |
0.04982 % | Verition Fund Management LLC | 74,234 | 74,234 | |
0.04790 % | Persky (Marla S) | 71,370 | 50,000 | |
0.04774 % | Mirae Asset Global Investments (USA) LLC | 71,133 | 71,132 | |
0.04726 % | Halkuff (Dawn) | 70,410 | 50,000 | |
0.04523 % | State Teachers Retirement System of Ohio | 67,400 | 6,900 | |
0.04500 % | Mariner Wealth Advisors | 67,055 | -31,016 | |
0.04401 % | SunAmerica Asset Management, LLC | 65,577 | -563 | |
0.04362 % | Bormann-Kennedy (Barbara-Jean Anne) | 65,000 | 50,000 | |
0.04246 % | Two Sigma Investments, LP | 63,262 | -76,699 | |
0.04230 % | GPS Wealth Strategies Group, LLC | 63,025 | 1,000 | |
0.04167 % | Soleus Capital Management, L.P. | 62,083 | 0 | |
0.04065 % | Assenagon Asset Management S.A. | 60,575 | -42 | |
0.04043 % | Parametric Portfolio Associates LLC | 60,238 | 27,062 | |
0.04040 % | SG Americas Securities, L.L.C. | 60,202 | 39,335 | |
0.04011 % | JPMorgan Private Bank (United States) | 59,761 | 7,590 | |
0.03962 % | Invesco Advisers, Inc. | 59,038 | 1,696 | |
0.03880 % | Manulife Investment Management (North America) Limited | 57,805 | 5,291 | |
0.03838 % | UBS Switzerland AG | 57,190 | 56,000 | |
0.03701 % | Graham Capital Management, L.P. | 55,141 | -31,478 | |
0.03651 % | IEQ Capital LLC | 54,393 | 0 | |
0.03571 % | StoneRidge Investment Partners, LLC | 53,211 | 0 | |
0.03515 % | DWS Investments UK Limited | 52,372 | -11,727 | |
0.03439 % | Chevy Chase Trust Company | 51,243 | 0 | |
0.03356 % | Weiss Asset Management | 50,001 | 0 | |
0.03356 % | Powell Investment Advisors, LLC | 50,000 | 50,000 | |
0.03271 % | Voya Investment Management LLC | 48,732 | 4,633 | |
0.03266 % | Dimensional Fund Advisors, L.P. | 48,663 | -6,437 | |