18.13645 % | OrbiMed Advisors, LLC | 9,907,945 | 0 | |
9.18576 % | Atlas Venture | 5,018,178 | 0 | |
8.72994 % | BVF Partners L.P. | 4,769,164 | 0 | |
7.48878 % | Blue Owl Capital Holdings LP | 4,091,118 | 200,000 | |
5.36604 % | Gilead Sciences Inc | 2,931,467 | 2,931,467 | |
4.11701 % | Omega Fund Management, LLC | 2,249,123 | 0 | |
3.99219 % | Cowen Investment Management LLC | 2,180,934 | 58,894 | |
2.49766 % | The Vanguard Group, Inc. | 1,364,470 | -167,699 | |
1.80835 % | Adage Capital Management, L.P. | 987,900 | 700,000 | |
1.07105 % | BML Capital Management LLC | 585,114 | 585,114 | |
1.04347 % | New Enterprise Associates (NEA) | 570,050 | 0 | |
0.87205 % | Renaissance Technologies LLC | 476,400 | -300,200 | |
0.77682 % | Jacobs Levy Equity Management, Inc. | 424,377 | -89,063 | |
0.75065 % | Two Sigma Investments, LP | 410,078 | 87,218 | |
0.73198 % | Acuitas Investments LLC | 399,879 | 2,133 | |
0.70038 % | Sofinnova Investments, Inc | 382,616 | 0 | |
0.64930 % | Millennium Management LLC | 354,710 | 354,710 | |
0.63949 % | BlackRock Institutional Trust Company, N.A. | 349,354 | -1,305,252 | |
0.59622 % | Acadian Asset Management LLC | 325,713 | 42,931 | |
0.46990 % | Geode Capital Management, L.L.C. | 256,707 | -340,570 | |
0.44790 % | Citadel Advisors LLC | 244,690 | 85,675 | |
0.42355 % | FNY Investment Advisers LLC | 231,383 | 231,383 | |
0.41363 % | Goldman Sachs & Company, Inc. | 225,964 | 153,367 | |
0.37313 % | Northern Trust Investments, Inc. | 203,843 | -17,418 | |
0.35886 % | Barclays Bank PLC | 196,044 | -776 | |
0.24766 % | Verition Fund Management LLC | 135,297 | -999,390 | |
0.15233 % | Susquehanna International Group, LLP | 83,218 | 83,218 | |
0.15065 % | Bridgeway Capital Management, LLC | 82,300 | 0 | |
0.14750 % | Deuterium Capital Management, LLC | 80,578 | 80,578 | |
0.14709 % | State Street Global Advisors (US) | 80,353 | -402,292 | |
0.13442 % | Centiva Capital, LP | 73,431 | 73,431 | |
0.13342 % | Marquette Wealth Management | 72,890 | 0 | |
0.13298 % | JBF Capital, Inc. | 72,647 | 72,647 | |
0.11833 % | Alpine Global Management, LLC | 64,641 | 64,641 | |
0.11098 % | Y-Intercept (Hong Kong) Ltd | 60,628 | 60,628 | |
0.10221 % | Jane Street Capital, L.L.C. | 55,840 | 55,840 | |
0.08763 % | Goldman Sachs Asset Management, L.P. | 47,870 | 47,870 | |
0.08546 % | Adar1 Capital Management LLC | 46,685 | 11,685 | |
0.08332 % | Point72 Asia (Singapore) Pte. Ltd. | 45,520 | 45,520 | |
0.08225 % | Marshall Wace LLP | 44,933 | -43,758 | |
0.07655 % | UBS Financial Services, Inc. | 41,818 | 9,069 | |
0.07190 % | Morgan Stanley & Co. LLC | 39,278 | -9,748 | |
0.07070 % | Dimensional Fund Advisors, L.P. | 38,621 | 0 | |
0.06396 % | Qube Research & Technologies Ltd | 34,941 | 34,941 | |
0.05535 % | Paloma Partners Management Company | 30,240 | 30,240 | |
0.05455 % | PGIM Quantitative Solutions LLC | 29,800 | 12,880 | |
0.05135 % | Virtu Americas LLC | 28,053 | 28,053 | |
0.05064 % | Squarepoint Capital LLP | 27,666 | 27,666 | |
0.05031 % | Dimensional Fund Advisors, Ltd. | 27,484 | 0 | |
0.04923 % | HRT Financial LP | 26,893 | 26,893 | |
0.04912 % | OUP Management Co., LLC | 26,833 | 26,833 | |
0.04545 % | Corsair Capital Management, L.P. | 24,830 | 24,830 | |
0.04002 % | AQR Capital Management, LLC | 21,861 | 21,861 | |
0.03685 % | Tower Research Capital LLC | 20,132 | 11,204 | |
0.03661 % | BBR Partners LLC | 20,000 | 20,000 | |
0.03661 % | Berkshire Asset Management, LLC | 20,000 | 20,000 | |
0.03618 % | Fidelity Management & Research Company LLC | 19,767 | 13,966 | |
0.03352 % | Vanguard Personalized Indexing Management, LLC | 18,310 | 18,310 | |
0.03040 % | XTX Markets LLC | 16,607 | -18,665 | |
0.02978 % | Mirae Asset Global Investments (USA) LLC | 16,270 | 16,270 | |
0.02792 % | SunAmerica Asset Management, LLC | 15,255 | -131 | |
0.02381 % | Northern Trust Global Investments | 13,008 | 0 | |
0.02209 % | Charles Schwab Investment Management, Inc. | 12,066 | -73,880 | |
0.02112 % | Vaughan Nelson Investment Management, L.P. | 11,540 | 0 | |
0.01005 % | BlackRock Investment Management, LLC | 5,488 | -60,540 | |
0.00916 % | Citi Investment Research (US) | 5,005 | -799 | |
0.00886 % | Cubist Systematic Strategies, LLC | 4,842 | 4,842 | |
0.00804 % | Point72 (DIFC) Ltd | 4,392 | 4,392 | |
0.00706 % | Rhumbline Advisers Ltd. Partnership | 3,856 | -23,957 | |
0.00549 % | Baystate Wealth Management LLC | 2,999 | 0 | |
0.00428 % | Mackenzie Investments | 2,336 | -3 | |
0.00424 % | Russell Investments Trust Company | 2,316 | 2,316 | |
0.00311 % | Blackstone Alternative Investment Advisors LLC | 1,700 | 1,400 | |
0.00290 % | Macquarie Investment Management Global Ltd. | 1,585 | 1,585 | |
0.00263 % | T. Rowe Price Associates, Inc. | 1,439 | 0 | |
0.00240 % | Morgan Stanley & Co. International Plc | 1,313 | 1,091 | |
0.00155 % | J.P. Morgan Securities plc | 849 | 0 | |
0.00155 % | Manulife Investment Management (North America) Limited | 848 | 0 | |
0.00076 % | ProFund Advisors LLC | 413 | -259 | |
0.00060 % | BofA Global Research (US) | 327 | -18,899 | |
0.00055 % | SRS Capital Advisors, Inc | 299 | 299 | |
0.00052 % | Morgan Stanley Investment Management Inc. (US) | 283 | 91 | |
0.00029 % | Guggenheim Investments | 161 | -303 | |
0.00020 % | Farther Finance Advisors, LLC | 108 | -62 | |
0.00018 % | NISA Investment Advisors, L.L.C. | 99 | 0 | |
0 % | ACCI Capital Investments SGIIC, SA | 0 | -170,000 | |
0 % | Invus Public Equities Advisors, LLC | 0 | -999,513 | |
0 % | Ergoteles Capital | 0 | -17,606 | |
0 % | MetLife Investment Management, LLC | 0 | -12,121 | |
0 % | Avoro Capital Advisors LLC | 0 | -1,640,000 | |
0 % | Avior Wealth Management, LLC | 0 | -3 | |
0 % | Carson Wealth Management Group | 0 | -985 | |
0 % | Anson Funds Management LP. | 0 | -209,315 | |
0 % | Oasis Management Company Ltd. | 0 | -140,000 | |
0 % | Morgan Stanley Smith Barney LLC | 0 | -45 | |
0 % | Assenagon Asset Management S.A. | 0 | -900 | |
0 % | BG Fund Management Luxembourg S.A. | 0 | -1,303 | |
0 % | Fidelity Institutional Asset Management | 0 | -1,126 | |
0 % | ProShare Advisors LLC | 0 | -4,146 | |
0 % | Acuta Capital Partners, LLC | 0 | -551,010 | |