13.85810 % | Auerbach (Alan H) | 6,802,940 | -40,805 | |
7.33138 % | The Vanguard Group, Inc. | 3,598,973 | 107,724 | |
6.44232 % | Millennium Management LLC | 3,162,533 | -4,930 | |
6.23866 % | Frazier Life Sciences Management, L.P. | 3,062,558 | 246,264 | |
5.97779 % | Acorn Bioventures L.P. | 2,934,496 | 194,561 | |
5.70638 % | BlackRock Institutional Trust Company, N.A. | 2,801,262 | 1,736,041 | |
3.97476 % | Acadian Asset Management LLC | 1,951,208 | -5,305 | |
3.57102 % | Renaissance Technologies LLC | 1,753,013 | 23,600 | |
3.02820 % | Great Point Partners, LLC | 1,486,544 | 142,916 | |
2.70616 % | Eversept Partners, LP | 1,328,454 | -98,043 | |
2.55940 % | Athyrium Capital Management, LP | 1,256,411 | 0 | |
1.93552 % | Geode Capital Management, L.L.C. | 950,146 | 497,175 | |
1.50520 % | American Century Investment Management, Inc. | 738,902 | 366,653 | |
1.23442 % | Dimensional Fund Advisors, L.P. | 605,977 | 37,684 | |
1.23143 % | BlackRock Financial Management, Inc. | 604,508 | 123,573 | |
1.04713 % | State Street Global Advisors (US) | 514,038 | 341,556 | |
0.92199 % | GlobeFlex Capital, L.P. | 452,606 | -39,145 | |
0.72217 % | Connor, Clark & Lunn Investment Management Ltd. | 354,514 | -31,349 | |
0.68060 % | Schonfeld Strategic Advisors LLC | 334,107 | 287,503 | |
0.61234 % | Winton Capital Management Ltd. | 300,599 | 112,316 | |
0.58981 % | SEI Investments Management Corporation | 289,537 | -140 | |
0.55644 % | Qube Research & Technologies Ltd | 273,158 | -114,020 | |
0.52203 % | Susquehanna International Group, LLP | 256,263 | -126,416 | |
0.50927 % | Affinity Asset Advisors LLC | 250,000 | 250,000 | |
0.40759 % | Marshall Wace LLP | 200,085 | -38,406 | |
0.40741 % | Tang Capital Management, LLC | 200,000 | 200,000 | |
0.38654 % | GSA Capital Partners LLP | 189,751 | 2,166 | |
0.34569 % | Two Sigma Investments, LP | 169,698 | -167,296 | |
0.32756 % | Newton Investment Management North America, LLC | 160,800 | 0 | |
0.32641 % | Federated MDTA LLC | 160,233 | -691 | |
0.32451 % | State Teachers Retirement System of Ohio | 159,300 | 159,300 | |
0.30469 % | Prospera Financial Services, Inc. | 149,570 | 1,778 | |
0.28397 % | Bridgeway Capital Management, LLC | 139,400 | 0 | |
0.27699 % | Morgan Stanley & Co. LLC | 135,972 | -177,328 | |
0.27353 % | Morgan Stanley Smith Barney LLC | 134,276 | -20,096 | |
0.25716 % | Charles Schwab Investment Management, Inc. | 126,240 | 106,787 | |
0.24118 % | BlackRock Investment Management, LLC | 118,394 | 104,872 | |
0.23766 % | Goldman Sachs & Company, Inc. | 116,668 | -322,927 | |
0.21981 % | Lazard Asset Management, L.L.C. | 107,903 | 58,437 | |
0.21261 % | Northern Trust Investments, Inc. | 104,370 | 21,521 | |
0.20945 % | PanAgora Asset Management Inc. | 102,820 | 102,820 | |
0.20458 % | Invesco Capital Management LLC | 100,427 | 100,427 | |
0.18961 % | Fidelity Management & Research Company LLC | 93,082 | 1,392 | |
0.18777 % | Arrowstreet Capital, Limited Partnership | 92,174 | -138,251 | |
0.18316 % | Nougues (Maximo F.) | 89,914 | -9,451 | |
0.18070 % | BNY Mellon Asset Management | 88,706 | 84,482 | |
0.17154 % | O'Shaughnessy Asset Management, LLC | 84,211 | 7,130 | |
0.17094 % | Goldman Sachs Asset Management, L.P. | 83,916 | 72,931 | |
0.15494 % | Stuglik (Brian M) | 76,058 | 17,100 | |
0.14543 % | Squarepoint Capital LLP | 71,391 | 10,757 | |
0.14517 % | Hunt (Douglas M) | 71,265 | -7,986 | |
0.14331 % | BMO Capital Markets (US) | 70,352 | -37,548 | |
0.14326 % | Wong (Alvin F) | 70,327 | 9,526 | |
0.13144 % | Goldman Sachs Asset Management International | 64,525 | 0 | |
0.12478 % | Macquarie Investment Management | 61,255 | 0 | |
0.12222 % | Dorval (Allison) | 60,000 | 16,000 | |
0.12135 % | AHL Partners LLP | 59,572 | -96,275 | |
0.12119 % | Mellon Investments Corporation | 59,491 | 35,622 | |
0.11834 % | Numeric Investors LLC | 58,093 | 2,258 | |
0.11781 % | Ludwig (Jeffrey Jerome) | 57,835 | -8,649 | |
0.11392 % | Nuveen LLC | 55,922 | 55,922 | |
0.11000 % | Cesano (Alessandra) | 54,000 | 27,000 | |
0.10894 % | Parametric Portfolio Associates LLC | 53,477 | -95,039 | |
0.10600 % | Avantis Investors | 52,035 | 52,035 | |
0.10240 % | Rhumbline Advisers Ltd. Partnership | 50,270 | 48,184 | |
0.09902 % | XTX Markets LLC | 48,611 | -5,542 | |
0.09844 % | Moyes (Jay M) | 48,322 | 5,000 | |
0.09574 % | Miller (Michael Patrick) | 47,000 | -23,358 | |
0.08172 % | Alpine Global Management, LLC | 40,116 | 40,116 | |
0.08052 % | Metis Global Partners, LLC | 39,527 | 0 | |
0.07767 % | Dimensional Fund Advisors, Ltd. | 38,127 | 0 | |
0.07491 % | BlackRock Investment Management (UK) Ltd. | 36,772 | -8,665 | |
0.06655 % | Trexquant Investment LP | 32,668 | 469 | |
0.06561 % | Brandywine Global Investment Management, LLC | 32,210 | 32,210 | |
0.06442 % | Barclays Bank PLC | 31,625 | 14,327 | |
0.06193 % | LSV Asset Management | 30,400 | 0 | |
0.06136 % | BofA Global Research (US) | 30,120 | 14,901 | |
0.05683 % | Wilson (Troy Edward) | 27,900 | 0 | |
0.05500 % | Senderowicz (Adrian M) | 27,000 | 0 | |
0.05493 % | State of Wyoming | 26,963 | 20,313 | |
0.04626 % | Mirae Asset Global Investments (USA) LLC | 22,710 | -639 | |
0.04536 % | Corebridge Financial Inc | 22,269 | 22,269 | |
0.04536 % | SunAmerica Asset Management, LLC | 22,269 | 0 | |
0.04400 % | Ritholtz Wealth Management LLC | 21,600 | -12,159 | |
0.04279 % | OxFORD Asset Management | 21,007 | 21,007 | |
0.04212 % | LPL Financial LLC | 20,677 | 0 | |
0.04141 % | UBS Financial Services, Inc. | 20,327 | 9,684 | |
0.04046 % | Citi Investment Research (US) | 19,860 | -110,613 | |
0.03915 % | Buckingham Strategic Partners, LLC | 19,220 | 0 | |
0.03870 % | The Patriot Financial Group, LLC | 19,000 | 8,000 | |
0.03749 % | Invesco Advisers, Inc. | 18,405 | 18,405 | |
0.03619 % | Manulife Investment Management (North America) Limited | 17,765 | 16,875 | |
0.03594 % | JPMorgan Private Bank (United States) | 17,641 | 17,641 | |
0.03582 % | PGIM Quantitative Solutions LLC | 17,585 | 2,385 | |
0.03374 % | Victory Capital Management Inc. | 16,565 | 16,565 | |
0.03351 % | Wells Fargo Bank, N.A. | 16,450 | 16,134 | |
0.03209 % | Jane Street Capital, L.L.C. | 15,755 | -413,496 | |
0.03178 % | Voya Investment Management LLC | 15,603 | 15,603 | |
0.02900 % | Marathon Trading Investment Management LLC | 14,236 | -56,064 | |
0.02885 % | Metropolitan Life Insurance Co. (US) | 14,163 | 14,163 | |