9.81472 % | Deep Track Capital LP | 5,972,257 | 222,257 | |
7.31631 % | T. Rowe Price Associates, Inc. | 4,451,972 | 642,260 | |
7.14721 % | BlackRock Institutional Trust Company, N.A. | 4,349,075 | 197,035 | |
6.42853 % | Fidelity Management & Research Company LLC | 3,911,759 | -34,738 | |
5.63321 % | The Vanguard Group, Inc. | 3,427,809 | -41,195 | |
5.58950 % | First Light Asset Management, LLC | 3,401,213 | -133,780 | |
5.27459 % | Redmile Group, LLC | 3,209,591 | 112,371 | |
5.02779 % | Paradigm BioCapital Advisors LP | 3,059,411 | 3,059,411 | |
4.95349 % | Cowen Investment Management LLC | 3,014,199 | -102,818 | |
4.93706 % | Blue Owl Capital Holdings LP | 3,004,199 | 0 | |
4.33338 % | Great Point Partners, LLC | 2,636,864 | 785,000 | |
4.10669 % | Laurion Capital Management LP | 2,498,920 | -975,824 | |
3.50512 % | Third Rock Ventures, LLC | 2,132,867 | 0 | |
3.31142 % | Polar Capital LLP | 2,015,000 | 0 | |
2.46530 % | DWS Investment GmbH | 1,500,133 | 45,000 | |
2.26150 % | State Street Global Advisors (US) | 1,376,120 | 57,353 | |
2.11518 % | Geode Capital Management, L.L.C. | 1,287,087 | 72,204 | |
2.10518 % | RA Capital Management, LP | 1,281,000 | 0 | |
1.96513 % | Pictet Asset Management Ltd. | 1,195,779 | -111,832 | |
1.68307 % | Franklin Advisers, Inc. | 1,024,147 | -501,132 | |
1.64339 % | Casdin Capital, LLC | 1,000,000 | 0 | |
1.61388 % | Granahan Investment Management, LLC | 982,049 | -64,796 | |
1.36929 % | Candriam Belgium S.A. | 833,216 | 285,216 | |
1.36929 % | Candriam Luxembourg S.A. | 833,216 | 0 | |
1.09298 % | Coulie (Bernard J) | 665,081 | 36,915 | |
1.05661 % | Morgan Stanley & Co. LLC | 642,945 | 300,172 | |
0.99301 % | BofA Global Research (US) | 604,245 | 106,431 | |
0.87441 % | Bessemer Trust Company, N.A. (US) | 532,079 | 0 | |
0.84328 % | Fernwood Investment Management, LLC. | 513,136 | 16,850 | |
0.71927 % | Northern Trust Investments, Inc. | 437,673 | -17,012 | |
0.71879 % | Charles Schwab Investment Management, Inc. | 437,382 | 7,096 | |
0.71532 % | Two Sigma Investments, LP | 435,272 | 178,748 | |
0.70783 % | Citadel Advisors LLC | 430,712 | -1,271,034 | |
0.63270 % | Rock Springs Capital Management LP | 384,996 | 0 | |
0.57089 % | AXA Investment Managers UK Ltd. | 347,389 | 195 | |
0.54822 % | Barclays Bank PLC | 333,592 | -26,553 | |
0.52370 % | Tepper (Robert I) | 318,672 | 89,168 | |
0.50176 % | Dimensional Fund Advisors, L.P. | 305,322 | 5,152 | |
0.47443 % | Partners HealthCare System, Inc | 288,690 | 0 | |
0.46210 % | ArrowMark Colorado Holdings, LLC | 281,189 | 0 | |
0.45548 % | Victory Capital Management Inc. | 277,162 | -73,301 | |
0.42490 % | Sphera Funds Management Ltd. | 258,554 | 0 | |
0.41638 % | Renaissance Technologies LLC | 253,369 | 177,469 | |
0.39030 % | Jane Street Capital, L.L.C. | 237,498 | 108,586 | |
0.38159 % | Checkpoint Capital L.P. | 232,200 | 232,200 | |
0.37248 % | BlackRock Financial Management, Inc. | 226,653 | 72,329 | |
0.36976 % | Capital Research Global Investors | 224,997 | 0 | |
0.36976 % | Capital International Investors | 224,997 | -1,152,330 | |
0.31464 % | Nuveen LLC | 191,457 | -18,801 | |
0.31273 % | Hull (Johannes P.) | 190,297 | 9,437 | |
0.31225 % | Cummings (Keith Lamont) | 190,007 | 10,402 | |
0.26346 % | BlackRock Investment Management, LLC | 160,318 | 25,362 | |
0.26081 % | Trexquant Investment LP | 158,700 | 158,700 | |
0.25837 % | Rice Hall James & Associates, LLC | 157,217 | 29,583 | |
0.25013 % | UBS Financial Services, Inc. | 152,202 | -212,862 | |
0.24708 % | T. Rowe Price International Ltd | 150,351 | 975 | |
0.24380 % | Goldman Sachs & Company, Inc. | 148,355 | -293,130 | |
0.23293 % | BlackRock Advisors (UK) Limited | 141,735 | 1,176 | |
0.22715 % | BNY Mellon Asset Management | 138,223 | 130 | |
0.21473 % | Lefebvre Eric | 130,664 | 11,744 | |
0.20615 % | BlackRock Asset Management Ireland Limited | 125,444 | 4,318 | |
0.20378 % | Exome Asset Management LLC | 124,000 | 124,000 | |
0.19762 % | Rhenman & Partners Asset Management AB | 120,250 | -25,000 | |
0.18447 % | TD Asset Management Inc. | 112,248 | 0 | |
0.17029 % | Woodline Partners LP | 103,623 | 3,480 | |
0.16460 % | Bond & Devick Wealth Partners | 100,160 | 0 | |
0.16434 % | Hudson Bay Capital Management LP | 100,000 | 30,600 | |
0.16394 % | Huh (Hoyoung) | 99,759 | 0 | |
0.15857 % | Rhumbline Advisers Ltd. Partnership | 96,488 | 14,662 | |
0.15669 % | T. Rowe Price Investment Management, Inc. | 95,348 | 5,714 | |
0.15324 % | ExodusPoint Capital Management, LP | 93,244 | 15,668 | |
0.15116 % | Harbor Capital Advisors, Inc. | 91,979 | 64,422 | |
0.15115 % | Hennion & Walsh Asset Management, Inc. | 91,974 | 23,685 | |
0.14528 % | Schweizerische Nationalbank | 88,400 | 0 | |
0.13719 % | Manulife Investment Management (North America) Limited | 83,483 | 1,191 | |
0.13245 % | Mellon Investments Corporation | 80,595 | 31,114 | |
0.13225 % | Squarepoint Capital LLP | 80,475 | 80,475 | |
0.12654 % | UBS O'Connor LLC | 77,000 | 77,000 | |
0.12180 % | American Century Investment Management, Inc. | 74,113 | 11,351 | |
0.12046 % | Nomura Asset Management Co., Ltd. | 73,300 | 73,300 | |
0.12044 % | Millennium Management LLC | 73,290 | 42,751 | |
0.11504 % | Abaris Investment Management AG | 70,000 | 56,900 | |
0.11478 % | Algert Global LLC | 69,842 | 52,912 | |
0.11093 % | HighMark Wealth Management LLC | 67,500 | 0 | |
0.10778 % | SEB Investment Management AB | 65,582 | 0 | |
0.10663 % | Goldman Sachs Asset Management, L.P. | 64,883 | 3,797 | |
0.10411 % | PDT Partners, LLC | 63,352 | 63,352 | |
0.09709 % | AllianceBernstein L.P. | 59,080 | 0 | |
0.09285 % | Verition Fund Management LLC | 56,501 | 56,501 | |
0.09070 % | Wells Fargo Advisors | 55,190 | 928 | |
0.08990 % | Medical Strategy GmbH | 54,703 | -116,175 | |
0.08929 % | State of Wisconsin Investment Board | 54,332 | 27,471 | |
0.08806 % | UBS Asset Management (Switzerland) | 53,585 | 7,485 | |
0.08217 % | Artia Global Partners LP | 50,000 | -50,000 | |
0.08124 % | HarbourVest Partners, L.L.C. | 49,434 | 0 | |
0.07736 % | Alps Advisors, Inc. | 47,074 | 4,589 | |
0.07658 % | Polar Asset Management Partners Inc. | 46,600 | -18,700 | |
0.07605 % | UBS Fund Management (Switzerland) AG | 46,278 | -18,747 | |
0.07592 % | Acuta Capital Partners, LLC | 46,200 | 46,200 | |
0.07580 % | BlackRock Investment Management (UK) Ltd. | 46,127 | 0 | |