21.54659 % | BVF Partners L.P. | 8,696,205 | 0 | |
4.77620 % | UBS Asset Management (Switzerland) | 1,927,674 | 1,055,016 | |
4.33598 % | Suvretta Capital Management, LLC | 1,750,000 | 0 | |
4.30904 % | Novartis AG | 1,739,130 | 0 | |
2.53251 % | GAM Investment Management (Switzerland) AG | 1,022,123 | 0 | |
1.90169 % | Stumpp (Michael Tobias) | 767,524 | 10,480 | |
1.82135 % | Amstutz (Patrick) | 735,095 | 39,175 | |
1.05863 % | UBS Fund Management (Switzerland) AG | 427,262 | 0 | |
1.03100 % | Union Bancaire Priv¿e | 416,111 | -3,788 | |
0.84321 % | Z¿rcher Kantonalbank (Asset Management) | 340,319 | 10,798 | |
0.67246 % | UBS Asset Management Switzerland AG | 271,403 | 0 | |
0.49554 % | ACATIS Investment Kapitalverwaltungsgesellschaft GmbH | 200,000 | 0 | |
0.30710 % | Zenito Oy | 123,946 | 0 | |
0.23023 % | Pictet Asset Management Ltd. | 92,921 | 9,000 | |
0.20904 % | Banque Cantonale Vaudoise | 84,367 | 0 | |
0.18867 % | BlackRock Advisors (UK) Limited | 76,146 | 516 | |
0.10290 % | Migros Bank Asset Management | 41,529 | 32,266 | |
0.07227 % | Leupin (Nicolas M.D., Ph.D.) | 29,168 | 12,368 | |
0.06678 % | Burns (William M) | 26,951 | 8,729 | |
0.06369 % | Zurcher (Alexander) | 25,706 | 6,627 | |
0.05700 % | Gloggner (Renate) | 23,006 | 19,094 | |
0.04781 % | DWS International GmbH | 19,295 | 0 | |
0.03646 % | Holtzman (Steven H) | 14,717 | 3,505 | |
0.02893 % | LLB Swiss Investment AG | 11,678 | 0 | |
0.01508 % | SEI Investments Canada | 6,087 | 0 | |
0.00869 % | Vasconcelles (Michael) | 3,507 | 3,507 | |
0.00869 % | Kapadia (Sandip) | 3,507 | 3,507 | |
0.00868 % | Palombella (Vito J) | 3,505 | 3,505 | |
0.00594 % | State Street Global Advisors (France) S.A. | 2,397 | 0 | |
0.00463 % | Dimensional Fund Advisors, L.P. | 1,869 | -4,682 | |
0.00329 % | LLB Asset Management AG | 1,327 | 0 | |
0.00207 % | Tolomeo Capital AG | 837 | 200 | |
0.00165 % | State Street Global Advisors (US) | 664 | 48 | |
0.00115 % | DFA Australia Ltd. | 463 | -1 | |
0.00003 % | American Century Investment Management, Inc. | 12 | 0 | |
0 % | Finlabo SIM S.p. A. | 0 | -14,273 | |
0 % | Quorus Verm¿gensverwaltung AG | 0 | -2,500 | |
0 % | Ethenea Independent Investors S.A. | 0 | -100,000 | |
0 % | Rieter Fischer Partners AG | 0 | -16,190 | |
0 % | Vanguard Investments Australia Ltd. | 0 | -3,170 | |
0 % | Russell Investments Limited | 0 | -908 | |
0 % | B¿loise Asset Management | 0 | -599 | |
0 % | Legal & General Investment Management Ltd. | 0 | -973 | |
0 % | Baillie Gifford & Co. | 0 | -96,900 | |
0 % | Banque Lombard Odier & Cie SA | 0 | -9,946 | |
0 % | BlackRock Institutional Trust Company, N.A. | 0 | -8,878 | |
0 % | Florida State Board of Administration | 0 | -6,757 | |
0 % | California State Teachers Retirement System | 0 | -21,727 | |
0 % | Tradition Wealth Management, LLC | 0 | -800 | |
0 % | P&S Verm¿gensberatungs AG Performance & Sicherheit | 0 | -5,000 | |
0 % | Mercer Global Investments Management Ltd | 0 | -6,688 | |