9.55576 % | Farallon Capital Management, L.L.C. | 7,913,123 | 3,401,370 | |
9.52339 % | The Vanguard Group, Inc. | 7,886,318 | 321,611 | |
9.20920 % | ARK Investment Management LLC | 7,626,139 | -556,035 | |
7.03983 % | BlackRock Institutional Trust Company, N.A. | 5,829,686 | 396,305 | |
6.57292 % | ARCH Venture Partners | 5,443,039 | 0 | |
5.06844 % | Fidelity Management & Research Company LLC | 4,197,179 | -483,371 | |
4.74527 % | State Street Global Advisors (US) | 3,929,557 | 437,402 | |
2.73751 % | MWG Management, Ltd. | 2,266,934 | -80,000 | |
2.68617 % | Nikko Asset Management Co., Ltd. | 2,224,415 | -137,402 | |
2.18932 % | Temasek Holdings Pte. Ltd. | 1,812,972 | 0 | |
2.08861 % | Geode Capital Management, L.L.C. | 1,729,581 | 92,859 | |
2.05659 % | Redmile Group, LLC | 1,703,061 | -176,556 | |
1.78997 % | First Trust Advisors L.P. | 1,482,271 | -41,085 | |
1.71250 % | Bellevue Asset Management AG | 1,418,121 | 225,000 | |
1.62978 % | T. Rowe Price Associates, Inc. | 1,349,624 | 145,102 | |
1.27016 % | BlackRock Financial Management, Inc. | 1,051,817 | 347,294 | |
1.26719 % | Dimensional Fund Advisors, L.P. | 1,049,360 | 407,499 | |
1.02101 % | Yiheng Capital Management, L.P. | 845,500 | 0 | |
1.01696 % | DWS Investments UK Limited | 842,147 | 804,446 | |
1.00199 % | Evans (John M.) | 829,750 | -60,000 | |
0.92882 % | Citadel Advisors LLC | 769,154 | 729,641 | |
0.81512 % | Casdin Capital, LLC | 675,000 | 0 | |
0.75310 % | Baillie Gifford & Co. | 623,640 | -128,754 | |
0.71642 % | Charles Schwab Investment Management, Inc. | 593,266 | 13,994 | |
0.71564 % | Northern Trust Investments, Inc. | 592,625 | -5,694 | |
0.56001 % | Goldman Sachs & Company, Inc. | 463,748 | 115,409 | |
0.55526 % | Morgan Stanley & Co. LLC | 459,814 | -3,266,261 | |
0.54367 % | Jane Street Capital, L.L.C. | 450,216 | 278,399 | |
0.49607 % | Norges Bank Investment Management (NBIM) | 410,799 | 397,912 | |
0.46250 % | Voloridge Investment Management, LLC | 382,995 | 146,608 | |
0.40044 % | BofA Global Research (US) | 331,605 | 44,317 | |
0.38836 % | Alphabet, Inc. | 321,604 | 0 | |
0.38741 % | Goldman Sachs Asset Management, L.P. | 320,815 | 116,942 | |
0.38628 % | UBS Asset Management (Switzerland) | 319,879 | 61,656 | |
0.37843 % | JPMorgan Asset Management U.K. Limited | 313,375 | -60,296 | |
0.36303 % | JP Morgan Asset Management | 300,624 | 274,105 | |
0.32605 % | Tang Capital Management, LLC | 270,000 | 270,000 | |
0.30180 % | Rock Springs Capital Management LP | 249,923 | 102,413 | |
0.29234 % | BlackRock Advisors (UK) Limited | 242,088 | 190 | |
0.29214 % | BlackRock Investment Management, LLC | 241,922 | 48,744 | |
0.27501 % | BlackRock Asset Management Ireland Limited | 227,732 | 21,754 | |
0.26161 % | Columbia Threadneedle Investments (US) | 216,642 | 1,427 | |
0.25422 % | Fidelity Institutional Asset Management | 210,516 | -3,387 | |
0.21910 % | Nuveen LLC | 181,436 | 8,909 | |
0.21692 % | BNY Mellon Asset Management | 179,634 | 466 | |
0.21330 % | Mirae Asset Global Investments (USA) LLC | 176,637 | -47,292 | |
0.21240 % | TD Asset Management Inc. | 175,892 | 13,200 | |
0.20017 % | Susquehanna International Group, LLP | 165,763 | 84,134 | |
0.19957 % | Rafferty Asset Management LLC | 165,264 | -79,090 | |
0.19752 % | Two Sigma Investments, LP | 163,565 | -343,433 | |
0.19606 % | UBS Financial Services, Inc. | 162,357 | -87,884 | |
0.18114 % | Wanjia Asset Management Co., Ltd. | 150,000 | -10,000 | |
0.17954 % | Russell Investments Trust Company | 148,674 | 4,846 | |
0.17456 % | Susquehanna Portfolio Strategies, LLC | 144,554 | 0 | |
0.17253 % | Morgan Stanley Investment Management Inc. (US) | 142,871 | -18,615 | |
0.16671 % | Parametric Portfolio Associates LLC | 138,053 | -23,364 | |
0.16555 % | Manulife Investment Management (North America) Limited | 137,089 | 32,279 | |
0.16508 % | Schweizerische Nationalbank | 136,700 | 0 | |
0.16009 % | Rhumbline Advisers Ltd. Partnership | 132,569 | 23,565 | |
0.15441 % | BlackRock Investment Management (UK) Ltd. | 127,871 | 36,387 | |
0.14249 % | BMO Nesbitt Burns Inc. | 118,000 | 118,000 | |
0.12670 % | Walleye Capital LLC | 104,924 | 7,187 | |
0.12361 % | Qube Research & Technologies Ltd | 102,359 | 4,304 | |
0.12003 % | Mellon Investments Corporation | 99,397 | 6,984 | |
0.11542 % | American Century Investment Management, Inc. | 95,578 | 23,837 | |
0.10730 % | BlackRock (Netherlands) B.V. | 88,853 | 86,720 | |
0.10640 % | AllianceBernstein L.P. | 88,110 | 0 | |
0.10383 % | Baillie Gifford Overseas Ltd. | 85,979 | 0 | |
0.10207 % | Citi Investment Research (US) | 84,524 | -168,851 | |
0.10093 % | Vestmark Advisory Solutions, Inc | 83,579 | -31,207 | |
0.09868 % | Barclays Bank PLC | 81,716 | -4,843 | |
0.09843 % | Ciaramella (Giuseppe) | 81,510 | -9,356 | |
0.09763 % | Millennium Management LLC | 80,844 | -26,343 | |
0.09661 % | Liontrust Investment Partners LLP | 80,000 | 0 | |
0.09464 % | Legal & General Investment Management Ltd. | 78,373 | 4,815 | |
0.09383 % | Capital Fund Management S.A. | 77,698 | 61,509 | |
0.08791 % | Adar1 Capital Management LLC | 72,800 | 72,800 | |
0.08333 % | Simon (Amy) | 69,004 | 68,048 | |
0.08247 % | California State Teachers Retirement System | 68,295 | -1,519 | |
0.07899 % | UBS Fund Management (Switzerland) AG | 65,408 | -35,136 | |
0.07870 % | Cathay Securities Investment Trust Co., Ltd. | 65,170 | 1,134 | |
0.07827 % | JPMorgan Private Bank (United States) | 64,818 | 19,007 | |
0.07815 % | Dimensional Fund Advisors, Ltd. | 64,715 | 857 | |
0.07632 % | Avantis Investors | 63,202 | 13,306 | |
0.07337 % | Emerge Canada Inc | 60,759 | 4,455 | |
0.07320 % | Nelsen (Robert Taylor) | 60,615 | 60,615 | |
0.07320 % | The Clarius Group, LLC | 60,615 | 0 | |
0.07136 % | MFS Investment Management | 59,095 | 59,095 | |
0.06524 % | Morgan Stanley Smith Barney LLC | 54,027 | -11,033 | |
0.06377 % | Polen Capital Management, LLC | 52,807 | 0 | |
0.06346 % | Northern Trust Global Investments | 52,555 | -955 | |
0.06264 % | Scientech Research LLC | 51,876 | 32,469 | |
0.06056 % | Fubon Asset Management Company Ltd. | 50,147 | -1,592 | |
0.06038 % | Deka Investment GmbH | 50,000 | 5,000 | |
0.06038 % | Deka Verm¿gensmanagement GmbH | 50,000 | 0 | |
0.05993 % | D.A. Davidson & Co.(Research) | 49,625 | 5,672 | |
0.05920 % | Tudor Investment Corporation | 49,022 | 1,177 | |
0.05685 % | Guggenheim Investments | 47,079 | -1,316 | |
0.05665 % | Lazard Asset Management, L.L.C. | 46,916 | -8,177 | |
0.05644 % | State of Wisconsin Investment Board | 46,738 | -2,521 | |