9.43118 % | Federated Hermes Global Investment Management Corp. | 1,956,488 | -301,636 | |
8.47032 % | Perceptive Advisors LLC | 1,757,160 | -182,563 | |
8.21407 % | Deep Track Capital LP | 1,704,000 | 579,579 | |
7.15163 % | Beryl Capital Management, LLC | 1,483,599 | 1,483,599 | |
6.56780 % | Chicago Capital, LLC | 1,362,484 | 242,710 | |
5.59137 % | BlackRock Institutional Trust Company, N.A. | 1,159,924 | 91,388 | |
5.18200 % | Carlson Capital, L.P. | 1,075,000 | 1,075,000 | |
4.81739 % | Millennium Management LLC | 999,363 | 611,796 | |
4.55643 % | The Vanguard Group, Inc. | 945,227 | 31,052 | |
4.45783 % | Franklin Advisers, Inc. | 924,773 | -487 | |
3.79208 % | ArrowMark Colorado Holdings, LLC | 786,664 | -4,585 | |
3.67866 % | Medical Strategy GmbH | 763,135 | 0 | |
3.05955 % | GW&K Investment Management, LLC | 634,701 | -9,091 | |
3.00480 % | Decheng Capital Management III (Cayman) LLC | 623,342 | 0 | |
2.47543 % | Rice Hall James & Associates, LLC | 513,525 | 9,387 | |
2.34624 % | Prosight Capital | 486,726 | -4,518 | |
2.23587 % | Sphera Funds Management Ltd. | 463,828 | 104,828 | |
1.98588 % | Tang Capital Management, LLC | 411,968 | -687,548 | |
1.67807 % | State Street Global Advisors (US) | 348,114 | -2,430 | |
1.64776 % | Saturn V Capital Management LLC | 341,827 | 341,827 | |
1.60623 % | Geode Capital Management, L.L.C. | 333,211 | 20,467 | |
1.47908 % | Platinum Asset Management | 306,834 | 39,917 | |
1.44735 % | Privium Fund Management BV | 300,252 | 0 | |
1.30023 % | Dimensional Fund Advisors, L.P. | 269,731 | 5,195 | |
1.28843 % | Great Point Partners, LLC | 267,283 | 267,283 | |
1.27918 % | MAI Capital Management, LLC | 265,364 | -141,469 | |
1.04705 % | Endurant Capital Management LP | 217,209 | 44,588 | |
0.89005 % | Cooper (Ronald Harold Wilfred) | 184,641 | -33,094 | |
0.75814 % | Northern Trust Investments, Inc. | 157,275 | 6,165 | |
0.60790 % | Fiera Capital Corporation | 126,109 | -2,377 | |
0.57347 % | Streck (Paul) | 118,966 | 55,000 | |
0.56399 % | Birchview Capital, LP | 117,000 | 0 | |
0.56099 % | EQT Life Sciences | 116,376 | 11,500 | |
0.48205 % | Samsara BioCapital, LLC | 100,000 | 0 | |
0.43231 % | Renaissance Technologies LLC | 89,683 | -50,000 | |
0.41716 % | BlackRock Financial Management, Inc. | 86,540 | 32,390 | |
0.39661 % | Morgan Stanley & Co. LLC | 82,277 | -7,959 | |
0.35647 % | Mattsson (Jan P) | 73,950 | -35,524 | |
0.31087 % | Duncan (Jason G) | 64,490 | -3,296 | |
0.29273 % | Parametric Portfolio Associates LLC | 60,726 | 29,482 | |
0.27362 % | Stephenson (Pamela) | 56,763 | -22,242 | |
0.25015 % | BNY Mellon Asset Management | 51,894 | 2,145 | |
0.24714 % | Carter (Martha J) | 51,268 | -3,656 | |
0.24560 % | Graham (Michelle) | 50,950 | -5,543 | |
0.23763 % | Charles Schwab Investment Management, Inc. | 49,296 | 2,462 | |
0.22929 % | BlackRock Investment Management, LLC | 47,565 | 1,062 | |
0.22498 % | Harford Simon N R | 46,671 | -13,739 | |
0.21692 % | Deka Vermögensmanagement GmbH | 45,000 | 0 | |
0.21601 % | Manulife Investment Management (North America) Limited | 44,811 | 37,853 | |
0.20535 % | Schweizerische Nationalbank | 42,600 | 1,700 | |
0.20505 % | Jacobs Levy Equity Management, Inc. | 42,538 | 42,538 | |
0.20327 % | Brandywine Global Investment Management, LLC | 42,168 | 0 | |
0.19407 % | Nuveen LLC | 40,260 | -52,803 | |
0.18318 % | International Biotechnology Trust PLC | 38,000 | 21,907 | |
0.17048 % | Aperio Group, LLC | 35,366 | 4,138 | |
0.17027 % | Weiss Multi-Strategy Advisers LLC | 35,322 | 322 | |
0.16872 % | Deka Investment GmbH | 35,000 | 35,000 | |
0.14232 % | Wilmington Trust Investment Advisors, Inc. | 29,524 | 4,562 | |
0.12148 % | AllianceBernstein L.P. | 25,200 | 2,300 | |
0.11666 % | Point72 Asset Management, L.P. | 24,200 | -53,900 | |
0.11492 % | Northern Trust Global Investments | 23,841 | 719 | |
0.11370 % | PDT Partners, LLC | 23,587 | 23,587 | |
0.10894 % | California State Teachers Retirement System | 22,599 | 645 | |
0.10823 % | Rhumbline Advisers Ltd. Partnership | 22,452 | 1,155 | |
0.09207 % | ARIAD Asset Management GmbH | 19,099 | 0 | |
0.08866 % | Schonfeld Strategic Advisors LLC | 18,393 | 18,393 | |
0.07791 % | Granite Investment Partners, LLC | 16,162 | -734 | |
0.07695 % | Apo Asset Management GmbH | 15,964 | 0 | |
0.07617 % | State of Wisconsin Investment Board | 15,802 | -1,081 | |
0.07451 % | William Blair & Company, L.L.C. (Research) | 15,456 | 75 | |
0.07035 % | State Street Global Advisors Ireland Limited | 14,594 | 0 | |
0.06841 % | Mellon Investments Corporation | 14,191 | 1,057 | |
0.06777 % | Alps Advisors, Inc. | 14,058 | 3,310 | |
0.06625 % | BlackRock Advisors (UK) Limited | 13,743 | 291 | |
0.06442 % | Cheyne Capital Management (UK) LLP | 13,364 | 13,364 | |
0.06310 % | Ensign Peak Advisors, Inc. | 13,090 | 6,450 | |
0.06290 % | Fidelity Management & Research Company LLC | 13,049 | 11,657 | |
0.06125 % | Goldman Sachs Asset Management, L.P. | 12,706 | 12,706 | |
0.05949 % | BofA Global Research (US) | 12,342 | 6,108 | |
0.05665 % | New York State Common Retirement Fund | 11,751 | -13 | |
0.05640 % | Jump Financial, LLC | 11,700 | 11,700 | |
0.05437 % | Credit Suisse Asset Management | 11,279 | 0 | |
0.05426 % | Dimensional Fund Advisors, Ltd. | 11,256 | 0 | |
0.05382 % | BlackRock Asset Management Ireland Limited | 11,164 | 513 | |
0.05303 % | Two Sigma Investments, LP | 11,000 | -900 | |
0.05128 % | JPMorgan Private Bank (United States) | 10,637 | 1,232 | |
0.05059 % | Hopkinson (Craig C M.D.) | 10,495 | 10,495 | |
0.04755 % | MetLife Investment Management, LLC | 9,864 | 0 | |
0.04687 % | Connor, Clark & Lunn Investment Management Ltd. | 9,724 | -337 | |
0.04478 % | Russell Investments Trust Company | 9,289 | 8,513 | |
0.04165 % | Cubist Systematic Strategies, LLC | 8,640 | 4,930 | |
0.04152 % | SunAmerica Asset Management, LLC | 8,613 | 442 | |
0.03783 % | DWS Investments UK Limited | 7,848 | 990 | |
0.03370 % | Legal & General Investment Management Ltd. | 6,990 | 434 | |
0.03193 % | E Fund Management Co. Ltd. | 6,623 | 4,498 | |
0.02971 % | UBS Financial Services, Inc. | 6,164 | 5,399 | |
0.02971 % | Barclays Bank PLC | 6,163 | 4,160 | |
0.02934 % | Horn Patrick Taylor | 6,086 | 2,066 | |
0.02892 % | Perinvest (UK) Ltd. | 6,000 | 0 | |
0.02754 % | Zürcher Kantonalbank (Asset Management) | 5,713 | 813 | |