11,54700 % | Fidelity Management & Research Company LLC | 14.392.175 | −238.466 | 30. 06. 2024. |
7,84422 % | The Vanguard Group, Inc. | 9.777.040 | 58.630 | 30. 06. 2024. |
7,11562 % | Janus Henderson Investors | 8.868.907 | 1.195.039 | 30. 06. 2024. |
6,58196 % | RA Capital Management, LP | 8.203.754 | 0 | 30. 06. 2024. |
6,32651 % | BlackRock Institutional Trust Company, N.A. | 7.885.361 | 314.385 | 30. 06. 2024. |
3,68507 % | Wellington Management Company, LLP | 4.593.066 | −326.304 | 30. 06. 2024. |
3,31639 % | Capital Research Global Investors | 4.133.544 | −6.977 | 30. 06. 2024. |
3,22737 % | T. Rowe Price Investment Management, Inc. | 4.022.589 | 469.622 | 30. 06. 2024. |
2,70150 % | State Street Global Advisors (US) | 3.367.147 | 30.055 | 30. 06. 2024. |
2,47001 % | T. Rowe Price Associates, Inc. | 3.078.615 | −8.212 | 30. 06. 2024. |
1,95906 % | Geode Capital Management, L.L.C. | 2.441.772 | 154.397 | 30. 06. 2024. |
1,74519 % | Franklin Advisers, Inc. | 2.175.205 | 278.124 | 30. 06. 2024. |
1,66957 % | Darwin Global Management Ltd | 2.080.946 | −669.858 | 30. 06. 2024. |
1,55227 % | Driehaus Capital Management, LLC | 1.934.747 | 66.940 | 30. 06. 2024. |
1,54794 % | Westfield Capital Management Company, L.P. | 1.929.348 | 343.253 | 30. 06. 2024. |
1,49439 % | Perceptive Advisors LLC | 1.862.608 | −70.151 | 30. 06. 2024. |
1,42423 % | Fidelity Institutional Asset Management | 1.775.165 | 144.647 | 30. 06. 2024. |
1,39187 % | AllianceBernstein L.P. | 1.734.821 | −45.882 | 30. 06. 2024. |
1,10970 % | Jennison Associates LLC | 1.383.131 | 126.248 | 30. 06. 2024. |
1,05138 % | Fred Alger Management, LLC | 1.310.436 | −86.275 | 30. 06. 2024. |
1,04702 % | Commodore Capital LP | 1.305.000 | 445.000 | 30. 06. 2024. |
0,98253 % | BlackRock Financial Management, Inc. | 1.224.621 | 45.069 | 30. 06. 2024. |
0,88254 % | Cormorant Asset Management, LP | 1.100.000 | 415.000 | 30. 06. 2024. |
0,83393 % | Frazier Life Sciences Management, L.P. | 1.039.405 | −100.000 | 30. 06. 2024. |
0,81758 % | Invesco Advisers, Inc. | 1.019.035 | −1.858 | 30. 06. 2024. |
0,80499 % | JP Morgan Asset Management | 1.003.336 | 37.836 | 30. 06. 2024. |
0,78985 % | Norges Bank Investment Management (NBIM) | 984.464 | 68.952 | 30. 06. 2024. |
0,72384 % | Fidelity Investments Canada ULC | 902.197 | 7.267 | 30. 06. 2024. |
0,70301 % | Charles Schwab Investment Management, Inc. | 876.237 | 42.619 | 30. 06. 2024. |
0,67245 % | Northern Trust Investments, Inc. | 838.142 | −28.926 | 30. 06. 2024. |
0,64851 % | Braidwell LP | 808.303 | −404.400 | 30. 06. 2024. |
0,63856 % | OrbiMed Advisors, LLC | 795.900 | −270.231 | 30. 06. 2024. |
0,63626 % | Pivotal Bioventure Partners Investment Advisor LLC | 793.036 | 0 | 30. 06. 2024. |
0,60433 % | Kynam Capital Management LP | 753.240 | 8.240 | 30. 06. 2024. |
0,60173 % | Novo Holdings A/S | 750.000 | −200.000 | 30. 09. 2024. |
0,59303 % | Eventide Asset Management, LLC | 739.153 | 81.947 | 30. 06. 2024. |
0,56716 % | Woodline Partners LP | 706.903 | 313.199 | 30. 06. 2024. |
0,55192 % | Maverick Capital, Ltd. | 687.908 | 332.777 | 30. 06. 2024. |
0,50321 % | Paradigm BioCapital Advisors LP | 627.202 | −612.793 | 30. 06. 2024. |
0,46133 % | Avoro Capital Advisors LLC | 575.000 | 0 | 30. 06. 2024. |
0,42755 % | Pictet Asset Management Ltd. | 532.904 | −328.665 | 30. 06. 2024. |
0,42329 % | American Century Investment Management, Inc. | 527.594 | 65.870 | 30. 06. 2024. |
0,37121 % | Ensign Peak Advisors, Inc. | 462.682 | −13.018 | 30. 06. 2024. |
0,35487 % | Amundi Asset Management US, Inc. | 442.308 | 139.951 | 30. 06. 2024. |
0,34321 % | Pickering (Grant E) | 427.779 | −15.000 | 08. 10. 2024. |
0,34150 % | Federated Hermes Global Investment Management Corp. | 425.640 | −110 | 30. 06. 2024. |
0,33594 % | Balyasny Asset Management LP | 418.715 | 418.715 | 30. 06. 2024. |
0,30929 % | BofA Global Research (US) | 385.494 | 175.420 | 30. 06. 2024. |
0,30538 % | Goldman Sachs & Company, Inc. | 380.629 | −31.175 | 30. 06. 2024. |
0,29462 % | Brown Advisory | 367.217 | 316.734 | 30. 06. 2024. |
0,27900 % | Goldman Sachs Asset Management, L.P. | 347.747 | 61.059 | 30. 06. 2024. |
0,27878 % | Allspring Global Investments, LLC | 347.474 | 3.922 | 30. 09. 2024. |
0,25459 % | Nuveen LLC | 317.323 | 10.052 | 30. 06. 2024. |
0,25066 % | TD Asset Management Inc. | 312.426 | 31.138 | 30. 06. 2024. |
0,24672 % | Victory Capital Management Inc. | 307.516 | 26.641 | 30. 06. 2024. |
0,24256 % | BlackRock Investment Management, LLC | 302.327 | 23.446 | 30. 06. 2024. |
0,24069 % | EcoR1 Capital, LLC | 300.000 | 0 | 30. 06. 2024. |
0,24069 % | Tang Capital Management, LLC | 300.000 | 0 | 30. 06. 2024. |
0,23267 % | Farallon Capital Management, L.L.C. | 290.000 | −87.400 | 30. 06. 2024. |
0,22917 % | Putnam Investment Management, L.L.C. | 285.640 | 41.171 | 30. 06. 2024. |
0,22786 % | Avidity Partners Management LP | 284.000 | 0 | 30. 06. 2024. |
0,22722 % | BlackRock Investment Management (UK) Ltd. | 283.204 | 26.464 | 30. 06. 2024. |
0,22653 % | Eagle Asset Management, Inc. | 282.351 | −56.449 | 30. 06. 2024. |
0,22416 % | Voya Investment Management LLC | 279.398 | 96.267 | 30. 06. 2024. |
0,21952 % | Cercano Management LLC | 273.608 | 1.457 | 30. 06. 2024. |
0,21905 % | Comerica, Inc. | 273.025 | 84.941 | 30. 06. 2024. |
0,21495 % | BNY Mellon Asset Management | 267.915 | 20.855 | 30. 06. 2024. |
0,20895 % | Columbia Threadneedle Investments (US) | 260.431 | 162.012 | 30. 06. 2024. |
0,20883 % | First Turn Management, LLC | 260.281 | 0 | 30. 06. 2024. |
0,19756 % | Lord, Abbett & Co. LLC | 246.242 | −138.121 | 30. 06. 2024. |
0,18470 % | D. E. Shaw & Co., L.P. | 230.207 | −137.042 | 30. 06. 2024. |
0,17755 % | Morgan Stanley & Co. LLC | 221.296 | −72.415 | 30. 06. 2024. |
0,17304 % | Saturn V Capital Management LP | 215.680 | 30.505 | 30. 06. 2024. |
0,16346 % | Millennium Management LLC | 203.731 | −3.251 | 30. 06. 2024. |
0,14934 % | ClearBridge Investments, LLC | 186.141 | 186.141 | 30. 06. 2024. |
0,14863 % | Soleus Capital Management, L.P. | 185.250 | −22.500 | 30. 06. 2024. |
0,14762 % | BlackRock Advisors (UK) Limited | 183.988 | 3.293 | 30. 09. 2024. |
0,14567 % | Parametric Portfolio Associates LLC | 181.563 | −7.614 | 30. 06. 2024. |
0,14546 % | Schweizerische Nationalbank | 181.300 | 3.300 | 30. 06. 2024. |
0,14135 % | Mellon Investments Corporation | 176.182 | 30.003 | 30. 06. 2024. |
0,13302 % | Citi Investment Research (US) | 165.795 | 20.928 | 30. 06. 2024. |
0,13226 % | SEI Investments Management Corporation | 164.843 | 67.939 | 30. 06. 2024. |
0,13032 % | Segall Bryant & Hamill, LLC | 162.432 | 4.411 | 30. 06. 2024. |
0,12780 % | Rhumbline Advisers Ltd. Partnership | 159.295 | 11.001 | 30. 06. 2024. |
0,12758 % | Macquarie Investment Management | 159.012 | 39.039 | 30. 06. 2024. |
0,12695 % | BlackRock Asset Management Ireland Limited | 158.235 | 1.236 | 30. 06. 2024. |
0,12258 % | California Public Employees' Retirement System | 152.778 | −4.208 | 30. 06. 2024. |
0,12050 % | Parkman Healthcare Partners LLC | 150.191 | 235 | 30. 06. 2024. |
0,12035 % | Ghost Tree Capital, LLC | 150.000 | 55.000 | 30. 06. 2024. |
0,11211 % | First Light Asset Management, LLC | 139.729 | 79.445 | 30. 06. 2024. |
0,10570 % | Manulife Investment Management (North America) Limited | 131.749 | 12.667 | 30. 06. 2024. |
0,10266 % | Barclays Bank PLC | 127.952 | −1.300 | 30. 06. 2024. |
0,09224 % | Pier Capital, LLC | 114.969 | −12.415 | 30. 06. 2024. |
0,09094 % | Tri Locum Partners LP | 113.344 | 113.344 | 30. 06. 2024. |
0,08858 % | Acuta Capital Partners, LLC | 110.400 | 5.570 | 30. 06. 2024. |
0,08672 % | Neuberger Berman, LLC | 108.092 | 5.781 | 30. 06. 2024. |
0,08554 % | Jane Street Capital, L.L.C. | 106.611 | 90.929 | 30. 06. 2024. |
0,08502 % | JPMorgan Asset Management U.K. Limited | 105.974 | 1.052 | 30. 06. 2024. |
0,08423 % | Legal & General Investment Management Ltd. | 104.984 | 10.201 | 30. 06. 2024. |
0,08336 % | MFS Investment Management | 103.906 | 2.967 | 31. 08. 2024. |