20,47890 % | RP Management, LLC | 34.471.927 | 2.638.593 | 27. 06. 2022. |
9,22169 % | PRIMECAP Management Company | 15.522.777 | 175.000 | 31. 03. 2022. |
5,51374 % | BlackRock Institutional Trust Company, N.A. | 9.281.231 | 3.008.931 | 31. 03. 2022. |
4,42595 % | The Vanguard Group, Inc. | 7.450.156 | 1.465.248 | 31. 03. 2022. |
4,31755 % | Rock Springs Capital Management LP | 7.267.696 | 3.460.034 | 31. 03. 2022. |
4,02458 % | Palo Alto Investors LP | 6.774.541 | 1.289.328 | 31. 03. 2022. |
3,92319 % | Platinum Asset Management | 6.603.870 | 3.780.934 | 31. 03. 2022. |
3,69504 % | Millennium Management LLC | 6.219.821 | 4.265.693 | 31. 03. 2022. |
3,35535 % | Goldman Sachs & Company, Inc. | 5.648.034 | 2.551.775 | 31. 03. 2022. |
2,72489 % | BofA Global Research (US) | 4.586.777 | 1.630.807 | 31. 03. 2022. |
2,49753 % | Citadel Advisors LLC | 4.204.066 | 3.427.731 | 31. 03. 2022. |
2,28016 % | Kleiner, Perkins, Caufield & Byers | 3.838.166 | 0 | 30. 09. 2021. |
2,03483 % | BioImpact Capital LLC | 3.425.202 | 0 | 31. 03. 2022. |
2,00854 % | Bay City Capital L.L.C. | 3.380.951 | 0 | 01. 03. 2022. |
1,91598 % | Assenagon Asset Management S.A. | 3.225.145 | 2.648.661 | 31. 03. 2022. |
1,73258 % | State Street Global Advisors (US) | 2.916.434 | 1.075.905 | 31. 03. 2022. |
1,55863 % | Fidelity Management & Research Company LLC | 2.623.632 | 1.758.259 | 31. 03. 2022. |
1,48519 % | Point72 Asset Management, L.P. | 2.500.000 | 2.500.000 | 31. 03. 2022. |
1,41625 % | Geode Capital Management, L.L.C. | 2.383.960 | 725.024 | 31. 03. 2022. |
1,37867 % | D. E. Shaw & Co., L.P. | 2.320.698 | 2.061.176 | 31. 03. 2022. |
0,89111 % | Woodline Partners LP | 1.500.000 | 1.500.000 | 31. 03. 2022. |
0,88803 % | Two Sigma Investments, LP | 1.494.816 | 156.789 | 31. 03. 2022. |
0,72170 % | Northern Trust Investments, Inc. | 1.214.833 | 378.581 | 31. 03. 2022. |
0,60662 % | Charles Schwab Investment Management, Inc. | 1.021.113 | 383.632 | 31. 03. 2022. |
0,59407 % | Baker Bros. Advisors LP | 1.000.000 | 1.000.000 | 31. 03. 2022. |
0,52019 % | BlackRock Asset Management Ireland Limited | 875.630 | 174.062 | 31. 03. 2022. |
0,48646 % | Norges Bank Investment Management (NBIM) | 818.853 | −86.712 | 31. 12. 2021. |
0,47348 % | CIBC Private Wealth Management | 797.000 | −85.000 | 31. 03. 2022. |
0,46115 % | Morgan Stanley & Co. LLC | 776.255 | 31.671 | 31. 03. 2022. |
0,43924 % | Frazier Healthcare Partners | 739.369 | 0 | 31. 03. 2022. |
0,39909 % | Renaissance Technologies LLC | 671.788 | 162.600 | 31. 03. 2022. |
0,27793 % | GSA Capital Partners LLP | 467.836 | 343.336 | 31. 03. 2022. |
0,27189 % | AQR Capital Management, LLC | 457.670 | 439.427 | 31. 03. 2022. |
0,27059 % | BNP Paribas Securities Corp. North America | 455.486 | −27.308 | 31. 03. 2022. |
0,26999 % | Redmile Group, LLC | 454.475 | 0 | 31. 03. 2022. |
0,19724 % | Hennion & Walsh Asset Management, Inc. | 332.004 | −10.823 | 30. 06. 2022. |
0,19432 % | Schweizerische Nationalbank | 327.100 | 170.100 | 31. 03. 2022. |
0,19212 % | Mott (David M) | 323.387 | 16.156 | 30. 06. 2022. |
0,18798 % | BlackRock Investment Management, LLC | 316.432 | 45.493 | 31. 03. 2022. |
0,17506 % | Acadian Asset Management LLC | 294.671 | 294.671 | 31. 03. 2022. |
0,17353 % | Nuveen LLC | 292.102 | 7.244 | 31. 03. 2022. |
0,17086 % | BNY Mellon Asset Management | 287.611 | 62.230 | 31. 03. 2022. |
0,15992 % | Bridgeway Capital Management, LLC | 269.200 | 269.200 | 31. 03. 2022. |
0,14852 % | NewGen Asset Management Limited | 250.000 | 250.000 | 31. 03. 2022. |
0,13093 % | BlackRock Financial Management, Inc. | 220.401 | 27.207 | 31. 03. 2022. |
0,12974 % | Tudor Investment Corporation | 218.384 | 75.737 | 31. 03. 2022. |
0,12072 % | Macquarie Investment Management | 203.200 | 0 | 31. 03. 2022. |
0,10779 % | California State Teachers Retirement System | 181.440 | 72.569 | 31. 03. 2022. |
0,10465 % | DWS Investments UK Limited | 176.158 | 121.662 | 31. 03. 2022. |
0,09686 % | NISA Investment Advisors, L.L.C. | 163.050 | 162.000 | 31. 03. 2022. |
0,09319 % | Susquehanna International Group, LLP | 156.867 | −158.595 | 31. 03. 2022. |
0,09227 % | Bazemore (Robert B) | 155.322 | 82.298 | 01. 03. 2022. |
0,08643 % | JP Morgan Asset Management | 145.484 | −3.308 | 31. 03. 2022. |
0,08540 % | Foresite Capital Management, LLC | 143.759 | −690.002 | 31. 03. 2022. |
0,08382 % | T. Rowe Price Associates, Inc. | 141.097 | 83.839 | 31. 03. 2022. |
0,08149 % | Mellon Investments Corporation | 137.165 | 51.224 | 31. 03. 2022. |
0,07727 % | Rhumbline Advisers Ltd. Partnership | 130.067 | 17.351 | 31. 03. 2022. |
0,07394 % | Northern Trust Global Investments | 124.455 | 47.395 | 31. 03. 2022. |
0,07362 % | Jane Street Capital, L.L.C. | 123.930 | −68.350 | 31. 03. 2022. |
0,07129 % | State of Wisconsin Investment Board | 120.000 | 0 | 31. 03. 2022. |
0,07022 % | Jennison Associates LLC | 118.200 | 97.200 | 31. 03. 2022. |
0,06847 % | Numeric Investors LLC | 115.254 | 115.254 | 31. 03. 2022. |
0,06719 % | UBS Asset Management (UK) Ltd. | 113.096 | 81.004 | 31. 03. 2022. |
0,06689 % | PGIM Quantitative Solutions LLC | 112.590 | 10.550 | 31. 03. 2022. |
0,06429 % | Credit Suisse Asset Management | 108.218 | 18.125 | 31. 03. 2022. |
0,06061 % | Mercer Global Investments Management Ltd | 102.029 | 0 | 30. 04. 2022. |
0,05906 % | Caxton Associates LP | 99.409 | 69.109 | 31. 03. 2022. |
0,05828 % | ExodusPoint Capital Management, LP | 98.107 | −261.365 | 31. 03. 2022. |
0,05727 % | AllianceBernstein L.P. | 96.400 | 297 | 31. 03. 2022. |
0,05644 % | LUNIS Vermögensmanagement AG | 95.000 | 0 | 30. 09. 2021. |
0,05591 % | Goldman Sachs Asset Management, L.P. | 94.106 | −52.966 | 31. 03. 2022. |
0,05416 % | Los Angeles Capital Management And Equity Research, Inc. | 91.173 | 88.793 | 31. 03. 2022. |
0,05186 % | Voya Investment Management LLC | 87.293 | 51.891 | 31. 03. 2022. |
0,05003 % | JPMorgan Private Bank (United States) | 84.209 | 33.332 | 31. 03. 2022. |
0,04767 % | BlackRock Advisors (UK) Limited | 80.246 | −779.015 | 30. 06. 2022. |
0,04456 % | Alpine Global Management, LLC | 75.000 | 25.608 | 31. 03. 2022. |
0,04283 % | Mirabella Financial Services LLP | 72.100 | 72.100 | 31. 03. 2022. |
0,04227 % | SunAmerica Asset Management, LLC | 71.149 | 22.537 | 31. 03. 2022. |
0,04202 % | BlackRock Investment Management (UK) Ltd. | 70.724 | 0 | 31. 03. 2022. |
0,04159 % | Virtu Americas LLC | 70.012 | 27.262 | 31. 03. 2022. |
0,04111 % | UBS Asset Management (Switzerland) | 69.197 | 0 | 31. 03. 2022. |
0,04105 % | XTX Markets LLC | 69.097 | 58.341 | 31. 03. 2022. |
0,03223 % | Conroy (Kevin T) | 54.258 | 10.204 | 30. 06. 2022. |
0,03203 % | Legal & General Investment Management Ltd. | 53.909 | −8.858 | 31. 03. 2022. |
0,03084 % | Manulife Investment Management (North America) Limited | 51.916 | 1.010 | 31. 12. 2021. |
0,03029 % | New York State Common Retirement Fund | 50.980 | −8 | 31. 03. 2022. |
0,02974 % | Agarwal (Shefali) | 50.060 | −35.753 | 01. 03. 2022. |
0,02970 % | FNY Investment Advisers LLC | 50.000 | 50.000 | 30. 06. 2022. |
0,02963 % | Lazard Asset Management, L.L.C. | 49.878 | 49.878 | 31. 03. 2022. |
0,02864 % | Invesco Advisers, Inc. | 48.217 | 11.068 | 31. 03. 2022. |
0,02806 % | Ros (Matthew) | 47.229 | −10.747 | 01. 03. 2022. |
0,02735 % | Beveridge (Roy A M.D.) | 46.037 | 8.928 | 30. 06. 2022. |
0,02710 % | Graham Capital Management, L.P. | 45.622 | −28.597 | 31. 03. 2022. |
0,02583 % | ProShare Advisors LLC | 43.486 | 8.868 | 31. 03. 2022. |
0,02562 % | Wedbush Securities, Inc. | 43.133 | 0 | 30. 06. 2022. |
0,02378 % | Morgan Stanley Smith Barney LLC | 40.030 | −1.597 | 31. 03. 2022. |
0,02234 % | Principal Global Investors (Equity) | 37.606 | 9.809 | 31. 03. 2022. |
0,02222 % | Arizona State Retirement System | 37.398 | 18.134 | 31. 03. 2022. |
0,02213 % | Florida State Board of Administration | 37.251 | −25.876 | 31. 03. 2022. |
0,02093 % | Northern Trust Global Investments Limited | 35.234 | 0 | 31. 03. 2022. |