ETF · Segment

Healthcare

Total ETFs

389

All Products

389 ETFs

Name	Asset class	AUM	Durch. Volume	Provider	Expense Ratio	Investment Segment	Index	Launch date	NAV (Net Asset Value)	P/B	P/E
IN Invesco Pharmaceuticals ETF ·	Stocks	542.27 M	36,692	IN Invesco	0.58	Healthcare	Dynamic Pharmaceutical Intellidex Index (AMEX)	6/23/2005	120.77	3.12	18.42
FU Fullgoal CSI Health Care 50 Index ETF ·	Stocks	532.22 M	—	FU Fullgoal	0.60	Healthcare	CSI Pharmaceutical 50 Index - CNY - Benchmark TR Gross	3/16/2020	0.94	0.00	0.00
SP State Street SPDR S&P U.S. Health Care Select Sector UCITS ETF (Acc) ·	Stocks	528.94 M	11,843	SP SPDR	0.15	Healthcare	S&P Health Care Select Sector Daily Capped 25/20 Index	7/7/2015	47.02	4.86	22.63
GU Guotai CSI SH-HK-SZ Brand Name Drug Industry ETF ·	Stocks	508.01 M	—	GU Guotai	0.60	Healthcare	CSI Shanghai-Hong Kong-Shenzhen Innovative Pharmaceutical Industry Index - CNY - Benchmark TR Gross	9/8/2021	0.75	3.53	27.58
CH ChinaAMC CSI All Share Health Care Instrument Index ETF ·	Stocks	489.93 M	—	CH ChinaAMC	0.60	Healthcare	CSI All-Medical Device Index - CNY - Benchmark TR Gross	11/23/2023	0.83	2.64	31.04
IN Invesco NASDAQ Biotech UCITS ETF ·	Stocks	478.09 M	32,199	IN Invesco	0.40	Healthcare	NASDAQ / Biotechnology	11/6/2014	72.43	4.94	21.49
VA VanEck Biotech ETF ·	Stocks	477.23 M	7,775	VA VanEck	0.35	Healthcare	MVIS US Listed Biotech 25	12/20/2011	237.84	4.63	23.20
SP State Street SPDR S&P Pharmaceuticals ETF ·	Stocks	462.1 M	141,141	SP SPDR	0.35	Healthcare	S&P Pharmaceuticals Select Industry	6/19/2006	62.87	3.51	16.73
MO Motilal Oswal S&P BSE Healthcare ETF ·	Stocks	448.37 M	—	MO Motilal Oswal	1.00	Healthcare	BSE Healthcare Index - INR - Benchmark TR Gross	7/29/2022	52.59	5.07	36.04
CS China Southern CSI Brand Name Drug Industry Exchange Traded Fund ·	Stocks	416.91 M	—	CS China Southern	0.20	Healthcare	CSI Innovative Pharmaceutical Industrial Index - CNY - Benchmark TR Gross	3/12/2021	0.65	3.14	28.61
IN Invesco Biotechnology & Genome ETF ·	Stocks	412.1 M	22,087	IN Invesco	0.59	Healthcare	Dynamic Biotech & Genome Intellidex Index (AMEX)	6/23/2005	94.74	4.40	17.88
MA Maxwealth CSI Hong Kong Connect Medical Treatment Thematic Index ETF Units ·	Stocks	405.18 M	—	MA Maxwealth	0.60	Healthcare	CSI Hong Kong Stock Connect Healthcare Index - CNY - Benchmark TR Net	4/2/2025	1.39	0.00	0.00
IS iShares MSCI World Health Care Sector Advanced UCITS ETF ·	Stocks	398.07 M	56,723	IS iShares	0.18	Healthcare	MSCI World Health Care ESG Reduced Carbon Select 20 35 Capped Index - Benchmark TR Net	11/3/2021	5.17	4.73	22.23
AM Amundi ETF ICAV - Amundi S&P World Health Care Screened UCITS ETF DR- EUR ·	Stocks	354.99 M	—	AM Amundi	0.18	Healthcare	S&P Developed Ex-Korea LargeMidCap Sustainability Enhanced Health Care Index - EUR - Benchmark TR Net	9/20/2022	10.66	4.64	21.76
EV Evolve Global Healthcare Enhanced Yield Fund ·	Stocks	341.43 M	22,861	EV Evolve	0.45	Healthcare	Solactive Global Healthcare 20 CAD Hedged Index - CAD	10/23/2017	17.33	4.23	21.55
LG L&G Healthcare Technology & Innovation UCITS ETF ·	Stocks	334.59 M	4,477	LG L&G	0.49	Healthcare	ROBO Global Healthcare Technology and Innovation ETF	7/2/2019	18.03	3.12	25.07
SI Simplify Health Care ETF ·	Stocks	327.21 M	108,743	SI Simplify	0.51	Healthcare		10/7/2021	37.83	4.73	22.97
XT Xtrackers MSCI Europe Health Care Screened UCITS ETF 1C ·	Stocks	307.01 M	3,099	XT Xtrackers	0.17	Healthcare	MSCI Europe Health Care ESG Screened 20-35 Index - EUR	6/26/2007	218.73	4.15	19.55
HA Harvest SSE Science and Technology Innovation Board Biopharmaceutical ETF ·	Stocks	290.17 M	—	HA Harvest	0.60	Healthcare	SSE Science and Technology Innovation Board Biomedical Index Yield - CNY - Benchmark TR Net	12/27/2023	1.05	0.00	0.00
CA Capital Nasdaq Biotechnology Index ETF ·	Stocks	285.17 M	—	CA Capital	1.01	Healthcare	NASDAQ / Biotechnology	1/9/2017	36.06	4.93	21.18
IN Invesco Dorsey Wright Healthcare Momentum ETF ·	Stocks	284.46 M	50,835	IN Invesco	0.74	Healthcare	Dorsey Wright Healthcare Tech Leaders TR	10/12/2006	58.53	5.92	26.92
HA Harvest Eli Lilly Enhanced High Income Shares ETF ·	Stocks	241.86 M	72,134	HA Harvest	0.40	Healthcare		8/21/2024	9.93	0.00	0.00
HA Hamilton Healthcare YIELD MAXIMIZER ETF ·	Stocks	233 M	46,304	HA Hamilton	0.65	Healthcare		2/6/2024	13.90	4.53	21.67
IS iShares US Medical Devices UCITS ETF USD ·	Stocks	231.7 M	121,757	IS iShares	0.25	Healthcare	Dow Jones U.S. Select Medical Equipment Capped 35/20 Index	8/3/2020	5.44	3.74	29.19
HF Harvest Bosera CSI Vaccine and Biotechnology Exchange Traded Fund Units ·	Stocks	230.12 M	—	HF Harvest Funds	0.60	Healthcare	CSI Vaccine and Biotechnology Index - CNY - Benchmark TR Gross	2/16/2023	0.69	2.19	38.23
YI YieldMax MRNA Option Income Strategy ETF ·	Alternatives	213.63 M	277,389	YI YieldMax	1.00	Healthcare		10/23/2023	38.63	0.00	0.00
PA PING AN CSI HK Connect Health Care Composite ETF ·	Stocks	208.11 M	—	PA Ping An	0.60	Healthcare	CSI Hong Kong Connect Healthcare - CNY - Benchmark TR Gross	12/16/2021	0.92	2.48	20.11
SP State Street SPDR S&P Health Care Services ETF ·	Stocks	206.67 M	29,833	SP SPDR	0.35	Healthcare	S&P Health Care Services Select Industry	9/28/2011	135.08	2.54	15.55
HA Harvest CSI Health Care and Medical 100 Strategy Exchange Traded Fund Units ·	Stocks	203.39 M	—	HA Harvest	0.60	Healthcare	CSI Medicine and Health 100 Strategy Index - CNY - Benchmark TR Gross	4/24/2020	0.82	2.79	22.89
HA Harvest Hang Seng Medical & Health Index ETF ·	Stocks	203.27 M	—	HA Harvest	0.60	Healthcare	Hang Seng Healthcare Index - CNY - Benchmark TR Gross	5/7/2024	1.55	2.67	20.30
TE Tema Oncology ETF ·	Stocks	203.21 M	32,866	TE Tema	0.99	Healthcare		8/14/2023	40.40	6.58	19.80
SY Sygnia Itrix Health Innovation Actively Managed ETF ·	Stocks	195.93 M	—	SY Sygnia	0.53	Healthcare		8/6/2021	29.49	4.30	21.13
CH ChinaAMC CSI Hong Kong Connect Medical Treatment Thematic Index Exchange Traded Fund Units ·	Stocks	190.36 M	—	CH ChinaAMC	0.60	Healthcare	CSI Hong Kong Stock Connect Healthcare Index - CNY - Benchmark TR Net	7/28/2025	0.89	0.00	0.00
AF ALPS Medical Breakthroughs ETF ·	Stocks	188.26 M	41,961	AF ALPS Funds	0.50	Healthcare	S-Network Medical Breakthroughs Index	12/30/2014	54.17	4.17	0.00
BM BMO Equal Weight US Health Care Hedged to CAD Index ETF ·	Stocks	184.5 M	1,454	BM BMO	0.39	Healthcare	Solactive Equal Weight U.S. Health Care Hedged to Canada Index - CAD	5/19/2010	77.85	3.67	20.81
GU Guotai Hang Seng Biotech Index ETF Units ·	Stocks	180.39 M	—	GU Guotai	0.00	Healthcare	Hang Seng Biotechnology Index - CNY - Benchmark TR Gross	1/21/2026	1.00	0.00	0.00
SP State Street SPDR S&P Health Care Equipment ETF ·	Stocks	178.43 M	28,475	SP SPDR	0.35	Healthcare	S&P Healthcare Equipment Select Industry	1/26/2011	89.21	2.50	21.37
IN Invesco S&P SmallCap Health Care ETF ·	Stocks	174.15 M	24,008	IN Invesco	0.29	Healthcare	S&P SmallCap 600 Capped Health Care Index - Benchmark TR Gross	4/7/2010	51.52	2.51	19.03
HW Huabao Csi Hong Kong Stock Connect Healthcare Theme ETF ·	Stocks	173.45 M	—	HW Hwabao	0.60	Healthcare	CSI Hong Kong Connect Healthcare - CNY - Benchmark TR Gross	—	0.93	0.00	0.00
BE BetaShares - Global Healthcare Currency Hedged ETF ·	Stocks	173.43 M	175,665	BE BetaShares	0.57	Healthcare	Nasdaq Global ex-Australia Healthcare Hedged AUD Index - AUD	8/4/2016	8.77	4.60	21.62
BO Bosera CSI Health Care 50 ETF ·	Stocks	168.87 M	—	BO Bosera	0.60	Healthcare	CSI Pharmaceutical 50 Index - CNY - Benchmark TR Gross	7/22/2021	0.58	3.89	25.29
EF E Fund Hang Seng Biotech ETF Units ·	Stocks	165.58 M	—	EF E Fund	0.00	Healthcare	Hang Seng Biotech Index - CNY - Benchmark TR Gross	10/20/2025	0.97	0.00	0.00
CH ChinaAMC CSI Biotechnology Thematic Exchange Traded Fund ·	Stocks	157.24 M	—	CH ChinaAMC	0.60	Healthcare		3/4/2021	0.62	2.79	29.27
DI Direxion Daily Healthcare Bull 3X ETF ·	Stocks	157.23 M	71,011	DI Direxion	0.94	Healthcare	S&P Health Care Select Sector	6/15/2011	125.78	4.83	22.47
GU Guotai CNI Vaccine and Biotechnology ETF ·	Stocks	155.73 M	—	GU Guotai	0.60	Healthcare	China Securities Vaccine and Biotechnology Index - Benchmark TR Gross	8/10/2022	0.58	0.00	0.00
IC ICBCCS CSI Brand Name Drug Industry Exchange Traded Fund Units ·	Stocks	155.32 M	—	IC ICBC	0.52	Healthcare	CSI Innovative Drug Industry Index - CNY - Benchmark TR Gross	2/9/2021	0.57	3.14	28.61
MI Middlefield Healthcare Dividend ETF Registered ·	Stocks	146.22 M	—	MI Middlefield	1.36	Healthcare		2/12/2019	11.40	4.83	24.11
TD TD Global Healthcare Leaders Index ETF ·	Stocks	136.67 M	8,707	TD TD	0.39	Healthcare	Solactive Global Healthcare Leaders Index - CAD - Benchmark TR Net	4/7/2021	20.57	3.51	20.54
EF E Fund CSI Hong Kong Connect Medical Treatment Thematic Index ETF Units ·	Stocks	132.35 M	—	EF E Fund	0.60	Healthcare	CSI Hong Kong Stock Connect Healthcare Index - CNY - Benchmark TR Net	12/31/2025	0.86	0.00	0.00
DI Direxion Daily S&P Biotech Bear 3X ETF ·	etf_assetclass_Leveraged/Inverse	131.32 M	15.34 M	DI Direxion	1.08	Healthcare	S&P Biotechnology Select Industry	5/28/2015	7.98	0.00	0.00
VI Virtus Biotech ETF ·	etf_assetclass_Sector Equity	126.54 M	10,575	VI Virtus	0.34	Healthcare	LifeSci Biotechnology Products Index	12/16/2014	101.23	5.54	0.00
AM Amundi S&P World Health Care Screened UCITS ETF -DR- EUR ·	Stocks	125.69 M	—	AM Amundi	0.18	Healthcare	S&P Developed Ex-Korea LargeMidCap Sustainability Enhanced Health Care Index - EUR - Benchmark TR Net	9/20/2022	10.22	2.89	19.72
SO Shinhan SOL Medical Device Materials Equipment ETF Units ·	Stocks	125.35 M	—	SO SOL	0.45	Healthcare	FnGuide Medical Device Director Index - KRW - Benchmark Price Return	8/22/2023	9,285.07	2.31	17.09
IS iShares S&P 500 Health Care Sector UCITS ETF ·	Stocks	120.75 M	12,003	IS iShares	0.18	Healthcare	S&P 500 CAPPED 35/20 HEALTH CARE NTR	6/15/2020	7.55	0.00	0.00
CI CI Health Care Giants Covered Call ETF ·	etf_assetclass_Sector Equity	116.59 M	5,126	CI CIGlobal	0.72	Healthcare		6/7/2018	11.10	3.88	17.87
FU Fullgoal Hang Seng Biotechnology ETF Units ·	Stocks	116.43 M	—	FU Fullgoal	0.60	Healthcare	Hang Seng Biotech Index - CNY - Benchmark TR Gross	12/24/2025	1.00	0.00	0.00
EM F/M Emerald Life Sciences Innovation ETF ·	Stocks	116 M	4,254	EM Emerald	0.79	Healthcare		10/30/2024	42.11	6.27	0.00
KR KraneShares MSCI All China Health Care Index ETF ·	Stocks	115 M	60,413	KR KraneShares	0.79	Healthcare	MSCI China All Shares Health Care 10/40 Index	1/31/2018	19.49	3.41	26.60
CS China Southern All Share Health Care ETF ·	Stocks	114.35 M	—	CS China Southern	0.60	Healthcare	CSI Full Index of Medical and Healthcare Equipment and Service Index - CNY - Benchmark TR Gross	10/22/2021	0.56	2.73	32.82
HA Harvest Healthcare Leaders Enhanced Income ETF ·	Stocks	112.47 M	70,445	HA Harvest	0.01	Healthcare		10/25/2022	8.41	0.00	0.00
IN Invesco Nasdaq Biotechnology ETF ·	Stocks	109.17 M	31,123	IN Invesco	0.19	Healthcare	NASDAQ / Biotechnology	6/11/2021	33.90	4.91	21.12
HE Harvest Healthcare Leaders Income ETF ·	Stocks	104.2 M	—	HE Harvest ETFs	1.06	Healthcare		1/17/2017	7.83	0.00	0.00
SA Satrix Healthcare Innovation Feeder ETF Accum Units ZAR ·	Stocks	100.55 M	—	SA Satrix	0.48	Healthcare	STOXX Global Breakthrough Healthcare (USD)(NR)	5/26/2022	73.03	0.00	0.00
RG ROBO Global Healthcare Technology and Innovation ETF ·	Stocks	94.6 M	32,473	RG ROBO Global	0.80	Healthcare	ROBO Global Healthcare Technology and Innovation ETF	6/25/2019	43.00	3.10	25.46
PR ProShares Ultra Health Care ·	Stocks	91.64 M	14,123	PR ProShares	1.07	Healthcare	S&P Health Care Select Sector	1/30/2007	57.64	0.00	0.00
PR ProShares Ultra Nasdaq Biotechnology ·	Stocks	89.8 M	10,874	PR ProShares	1.19	Healthcare	NASDAQ / Biotechnology	4/7/2010	106.90	0.00	0.00
DE Daily Target 2X Long LLY ETF ·	etf_assetclass_Leveraged/Inverse	84.45 M	370,317	DE Defiance	1.49	Healthcare		8/7/2024	24.37	0.00	0.00
MI Middlefield Healthcare Dividend ETF ·	Stocks	84.3 M	1,274	MI Middlefield	0.85	Healthcare		7/21/2017	10.44	0.00	0.00
CI CI Global Healthcare Leaders Index ETF Trust Units -Unhedged- ·	Stocks	82.21 M	—	CI CI	0.56	Healthcare	Solactive Developed Markets Healthcare 150 CAD Index - CAD - Benchmark TR Net	8/17/2021	23.70	0.00	0.00
IS iShares Nasdaq US Biotechnology UCITS ETF ·	Stocks	79.27 M	34,292	IS iShares	0.35	Healthcare	NASDAQ / Biotechnology	3/5/2018	9.93	4.93	21.38
CA Guotai GEM Health Care Index ETF Units ·	Stocks	78.35 M	—	CA Cathay	0.00	Healthcare	ChiNext Medical and Healthcare Index - CNY - Benchmark TR Net	4/2/2025	1.07	0.00	0.00
KS KSM ETF (4D) S&P Health Care Units ·	Stocks	78.23 M	—	KS KSM	0.73	Healthcare	S&P Health Care Select Sector	12/4/2018	48.79	0.00	0.00
DE Daily Target 2X Long MRNA ETF ·	etf_assetclass_Leveraged/Inverse	69.08 M	213,526	DE Defiance	1.34	Healthcare		2/3/2026	130.35	0.00	0.00
BF Brompton Global Healthcare Income & Growth ETF ·	Stocks	66.77 M	3,491	BF Brompton Funds	0.75	Healthcare		9/24/2015	7.27	6.13	23.54
LE Leverage Shares 2x Long UNH Daily ETF ·	Stocks	62.9 M	731,785	LE LeverageShares	0.75	Healthcare		7/22/2025	17.92	0.00	0.00
CH ChinaAMC SSE STAR Biology and Medicine Index ETF Units ·	Stocks	62.41 M	—	CH ChinaAMC	0.00	Healthcare	Shanghai Stock Exchange Science and Technology Innovation Board Biopharmaceutical Index - CNY - Benchmark TR Gross	5/14/2025	1.08	0.00	0.00
DE Daily Target 2X Long HIMS ETF ·	Stocks	56.86 M	418,807	DE Defiance	1.33	Healthcare		3/12/2025	26.82	0.00	0.00
RI Roundhill Investments - GLP-1 & Weight Loss ETF ·	Stocks	56.4 M	20,405	RI Roundhill Investments	0.59	Healthcare		5/21/2024	30.16	4.01	14.05
TE Tema Heart & Health ETF ·	Stocks	52.83 M	4,768	TE Tema	0.99	Healthcare		11/20/2023	35.69	6.56	21.55
FI Fidelity Disruptive Medicine ETF ·	Stocks	52.31 M	7,326	FI Fidelity	0.50	Healthcare		4/16/2020	31.02	4.23	37.59
VA VanEck Global Healthcare Leaders ETF ·	Stocks	50.79 M	—	VA VanEck	0.45	Healthcare	MarketGrader Developed Markets ex-Australia Health Care Index - AUD	9/8/2020	11.35	4.95	21.34
AD AdvisorShares Psychedelics ETF ·	Stocks	48.22 M	40,688	AD AdvisorShares	1.84	Healthcare		9/15/2021	21.29	3.48	0.00
GX Global X - S&P Biotech ETF ·	Stocks	47.35 M	2,197	GX Global X	0.45	Healthcare	S&P Biotechnology Select Industry	11/8/2018	73.52	5.08	0.00
MI Middlefield Health & Wellness ETF ·	Stocks	45.87 M	33	MI Middlefield	0.27	Healthcare		10/20/2016	12.33	4.47	21.53
HA Harbor Health Care ETF (MEDI) ·	Stocks	41.27 M	4,961	HA Harbor	0.80	Healthcare		11/16/2022	32.54	11.65	33.30
VI Virtus Biotech Clinical Trials ETF ·	etf_assetclass_Sector Equity	41.18 M	21,462	VI Virtus	0.65	Healthcare	LifeSci Biotechnology Clinical Trials Index	12/16/2014	43.35	4.22	0.00
FU Fuguo Guozheng Vaccine & Biotechnology ETF ·	Stocks	40.7 M	—	FU Fullgoal	0.60	Healthcare	CSI Vaccine and Biotechnology Index - CNY - Benchmark TR Gross	9/16/2022	0.66	2.00	29.03
IS iShares Evolved U.S. Healthcare Staples ETF ·	Stocks	38.78 M	7,141	IS iShares	0.18	Healthcare		3/21/2018	41.39	4.27	23.49
DE Defiance Daily Target 2X Long NVO ETF ·	Stocks	38.53 M	446,069	DE Defiance	1.31	Healthcare		12/2/2024	9.20	0.00	0.00
IS iShares Evolved U.S. Innovative Healthcare ETF ·	Stocks	36.79 M	3,797	IS iShares	0.18	Healthcare		3/21/2018	34.13	5.85	16.28
PU Unitedhealth Group Unh Yield Shares Purpose ETF ·	Stocks	36.24 M	—	PU Purpose	0.00	Healthcare		2/7/2025	7.98	0.00	0.00
TR Investment Managers Series Trust II - Tradr 2X Long TEM Daily ETF ·	Stocks	35.65 M	279,599	TR Tradr	1.30	Healthcare		5/12/2025	27.89	0.00	0.00
EV Evolve Global Healthcare Enhanced Yield Fund ·	Stocks	32.67 M	—	EV Evolve	0.72	Healthcare	Solactive Global Healthcare 20 Index - CAD	10/25/2017	22.60	0.00	0.00
TR T. Rowe Price Exchange-Traded Funds, Inc. - T. Rowe Price Health Care ETF ·	Stocks	32.37 M	6,879	TR T. Rowe	0.44	Healthcare		6/11/2025	33.20	3.97	25.60
TA Tachlit SAL 4D NASDAQ Biotechnology ETF ·	Stocks	31.72 M	—	TA Tachlit	1.23	Healthcare	NASDAQ / Biotechnology	11/13/2018	152.42	0.00	0.00
GX Global X HealthTech ETF ·	Stocks	30.71 M	8,436	GX Global X	0.50	Healthcare	Global X HealthTech Index - Benchmark TR Net	7/29/2020	29.25	3.67	26.47
HE Harvest Eli Lilly High Income Shares ETF ·	Stocks	30.63 M	—	HE Harvest ETFs	0.00	Healthcare		8/21/2024	9.22	0.00	0.00
SM SmartShares - Smart Healthcare Innovation ETF ·	etf_assetclass_Sector Equity	30.16 M	10,843	SM Smartshares	0.75	Healthcare	STOXX Global Breakthrough Healthcare (USD)(NR)	6/6/2019	4.22	0.00	0.00
BM BMO Covered Call Health Care ETF CAD Units Trust Unit ·	Stocks	28.21 M	—	BM BMO	0.78	Healthcare		1/23/2023	26.39	4.17	22.59
SP State Street Health Care Select Sector SPDR Premium Income ETF ·	Stocks	27.94 M	36,334	SP SPDR	0.35	Healthcare	S&P Health Care Select Sector	7/29/2025	25.87	0.00	0.00

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