ETF · Segment

Healthcare

Total ETFs

389

All Products

389 ETFs

Name	Asset class	AUM	Durch. Volume	Provider	Expense Ratio	Investment Segment	Index	Launch date	NAV (Net Asset Value)	P/B	P/E
MA Maxwealth CSI Hong Kong Connect Medical Treatment Thematic Index ETF Units ·	Stocks	405.18 M	—	MA Maxwealth	0.60	Healthcare	CSI Hong Kong Stock Connect Healthcare Index - CNY - Benchmark TR Net	4/2/2025	1.39	0.00	0.00
IN Invesco Pharmaceuticals ETF ·	Stocks	400.86 M	17,717.46	IN Invesco	0.57	Healthcare	Dynamic Pharmaceutical Intellidex Index (AMEX)	6/23/2005	103.12	3.12	18.42
IN Invesco Health Care S&P US Select Sector UCITS ETF ·	Stocks	376.67 M	—	IN Invesco	0.14	Healthcare	S&P Select Sector Capped 20% Health Care Index	12/16/2009	720.81	5.12	22.97
VA VanEck Biotech ETF ·	Stocks	373.94 M	6,300.79	VA VanEck	0.35	Healthcare	MVIS US Listed Biotech 25	12/20/2011	187.81	4.63	23.20
AM Amundi ETF ICAV - Amundi S&P World Health Care Screened UCITS ETF DR- EUR ·	Stocks	354.99 M	—	AM Amundi	0.18	Healthcare	S&P Developed Ex-Korea LargeMidCap Sustainability Enhanced Health Care Index - EUR - Benchmark TR Net	9/20/2022	10.66	4.64	21.76
IS iShares MSCI World Health Care Sector Advanced UCITS ETF Accum Shs USD ·	Stocks	312.57 M	—	IS iShares	0.25	Healthcare	MSCI World Health Care ESG Reduced Carbon Select 20 35 Capped Index - Benchmark TR Net	11/3/2021	5.21	4.73	22.23
SP State Street SPDR S&P Pharmaceuticals ETF ·	Stocks	304.09 M	68,745.9	SP SPDR	0.35	Healthcare	S&P Pharmaceuticals Select Industry	6/19/2006	51.92	3.51	16.73
HA Harvest SSE Science and Technology Innovation Board Biopharmaceutical ETF ·	Stocks	290.17 M	—	HA Harvest	0.60	Healthcare	SSE Science and Technology Innovation Board Biomedical Index Yield - CNY - Benchmark TR Net	12/27/2023	1.05	0.00	0.00
CA Capital Nasdaq Biotechnology Index ETF ·	Stocks	285.17 M	—	CA Capital	1.01	Healthcare	NASDAQ / Biotechnology	1/9/2017	36.06	4.93	21.18
EV Evolve Global Healthcare Enhanced Yield Fund ·	Stocks	267.11 M	—	EV Evolve	0.74	Healthcare	Solactive Global Healthcare 20 CAD Hedged Index - CAD	10/25/2017	17.79	4.23	21.55
XT Xtrackers MSCI Europe Health Care Screened UCITS ETF -1C- Capitalisation ·	Stocks	260.14 M	—	XT Xtrackers	0.20	Healthcare	MSCI Europe Health Care ESG Screened 20-35 Index - EUR	6/26/2007	224.14	4.15	19.55
IN Invesco Biotechnology & Genome ETF ·	Stocks	247.28 M	7,319.98	IN Invesco	0.58	Healthcare	Dynamic Biotech & Genome Intellidex Index (AMEX)	6/23/2005	78.89	4.40	17.88
SI Simplify Health Care ETF ·	Stocks	230.58 M	158,683.9	SI Simplify	0.51	Healthcare		10/7/2021	33.85	4.73	22.97
HF Harvest Bosera CSI Vaccine and Biotechnology Exchange Traded Fund Units ·	Stocks	230.12 M	—	HF Harvest Funds	0.60	Healthcare	CSI Vaccine and Biotechnology Index - CNY - Benchmark TR Gross	2/16/2023	0.69	2.19	38.23
PA PING AN CSI HK Connect Health Care Composite ETF ·	Stocks	208.11 M	—	PA Ping An	0.60	Healthcare	CSI Hong Kong Connect Healthcare - CNY - Benchmark TR Gross	12/16/2021	0.92	2.48	20.11
HA Harvest CSI Health Care and Medical 100 Strategy Exchange Traded Fund Units ·	Stocks	203.39 M	—	HA Harvest	0.60	Healthcare	CSI Medicine and Health 100 Strategy Index - CNY - Benchmark TR Gross	4/24/2020	0.82	2.79	22.89
HA Harvest Hang Seng Medical & Health Index ETF ·	Stocks	203.27 M	—	HA Harvest	0.60	Healthcare	Hang Seng Healthcare Index - CNY - Benchmark TR Gross	5/7/2024	1.55	2.67	20.30
SY Sygnia Itrix Health Innovation Actively Managed ETF ·	Stocks	195.93 M	—	SY Sygnia	0.53	Healthcare		8/6/2021	29.49	4.30	21.13
CH ChinaAMC CSI Hong Kong Connect Medical Treatment Thematic Index Exchange Traded Fund Units ·	Stocks	190.36 M	—	CH ChinaAMC	0.60	Healthcare	CSI Hong Kong Stock Connect Healthcare Index - CNY - Benchmark TR Net	7/28/2025	0.89	0.00	0.00
LG Legal & General UCITS ETF Plc - Healthcare Breakthrough ·	Stocks	182.61 M	—	LG L&G	0.49	Healthcare	ROBO Global Healthcare Technology and Innovation ETF	6/17/2019	13.87	3.12	25.07
GU Guotai Hang Seng Biotech Index ETF Units ·	Stocks	180.39 M	—	GU Guotai	0.00	Healthcare	Hang Seng Biotechnology Index - CNY - Benchmark TR Gross	1/21/2026	1.00	0.00	0.00
HA Hamilton Healthcare YIELD MAXIMIZER (TM) ETF Trust Units E ·	Stocks	177.34 M	—	HA Hamilton	0.00	Healthcare		2/6/2024	13.45	4.53	21.67
HE Harvest Eli Lilly Enhanced High Income Shares ETF ·	Stocks	174.36 M	—	HE Harvest ETFs	0.00	Healthcare		8/21/2024	8.32	0.00	0.00
HW Huabao Csi Hong Kong Stock Connect Healthcare Theme ETF ·	Stocks	173.45 M	—	HW Hwabao	0.60	Healthcare	CSI Hong Kong Connect Healthcare - CNY - Benchmark TR Gross	—	0.93	0.00	0.00
TE Tema Oncology ETF ·	Stocks	170.02 M	25,898.86	TE Tema	0.75	Healthcare		8/15/2023	37.07	6.58	19.80
BO Bosera CSI Health Care 50 ETF ·	Stocks	168.87 M	—	BO Bosera	0.60	Healthcare	CSI Pharmaceutical 50 Index - CNY - Benchmark TR Gross	7/22/2021	0.58	3.89	25.29
BE BetaShares Global Healthcare ETF - Currency Hedged ·	Stocks	166.88 M	—	BE BetaShares	0.57	Healthcare	Nasdaq Global ex-Australia Healthcare Hedged AUD Index - AUD	8/4/2016	8.40	4.60	21.62
BM BMO Equal Weight US Health Care Hedged to CAD Index ETF ·	Stocks	166.72 M	—	BM BMO	0.39	Healthcare	Solactive Equal Weight U.S. Health Care Hedged to Canada Index - CAD	5/19/2010	64.43	3.67	20.81
EF E Fund Hang Seng Biotech ETF Units ·	Stocks	165.58 M	—	EF E Fund	0.00	Healthcare	Hang Seng Biotech Index - CNY - Benchmark TR Gross	10/20/2025	0.97	0.00	0.00
CH ChinaAMC CSI Biotechnology Thematic Exchange Traded Fund ·	Stocks	157.24 M	—	CH ChinaAMC	0.60	Healthcare		3/4/2021	0.62	2.79	29.27
GU Guotai CNI Vaccine and Biotechnology ETF ·	Stocks	155.73 M	—	GU Guotai	0.60	Healthcare	China Securities Vaccine and Biotechnology Index - Benchmark TR Gross	8/10/2022	0.58	0.00	0.00
IC ICBCCS CSI Brand Name Drug Industry Exchange Traded Fund Units ·	Stocks	155.32 M	—	IC ICBC	0.52	Healthcare	CSI Innovative Drug Industry Index - CNY - Benchmark TR Gross	2/9/2021	0.57	3.14	28.61
IS iShares US Medical Devices UCITS ETF USD ·	Stocks	147.18 M	—	IS iShares	0.25	Healthcare	Dow Jones U.S. Select Medical Equipment Capped 35/20 Index	8/3/2020	5.78	3.74	29.19
MI Middlefield Healthcare Dividend ETF Registered ·	Stocks	146.22 M	—	MI Middlefield	1.36	Healthcare		2/12/2019	11.40	4.83	24.11
SP State Street SPDR S&P Health Care Equipment ETF ·	Stocks	138.96 M	17,115.47	SP SPDR	0.35	Healthcare	S&P Healthcare Equipment Select Industry	1/26/2011	77.11	2.50	21.37
EF E Fund CSI Hong Kong Connect Medical Treatment Thematic Index ETF Units ·	Stocks	132.35 M	—	EF E Fund	0.60	Healthcare	CSI Hong Kong Stock Connect Healthcare Index - CNY - Benchmark TR Net	12/31/2025	0.86	0.00	0.00
DI Direxion Daily Healthcare Bull 3X ETF ·	Stocks	131.5 M	46,503.64	DI Direxion	0.94	Healthcare	S&P Health Care Select Sector	6/15/2011	91.98	4.83	22.47
YI YieldMax MRNA Option Income Strategy ETF ·	Stocks	126.43 M	198,456.2	YI YieldMax	1.00	Healthcare		10/23/2023	17.80	0.00	0.00
AL ALPS Medical Breakthroughs ETF ·	Stocks	126.28 M	32,689.53	AL ALPS	0.50	Healthcare	S-Network Medical Breakthroughs Index	12/31/2014	48.43	4.17	0.00
AM Amundi S&P World Health Care Screened UCITS ETF -DR- EUR ·	Stocks	125.69 M	—	AM Amundi	0.18	Healthcare	S&P Developed Ex-Korea LargeMidCap Sustainability Enhanced Health Care Index - EUR - Benchmark TR Net	9/20/2022	10.22	2.89	19.72
SO Shinhan SOL Medical Device Materials Equipment ETF Units ·	Stocks	125.35 M	—	SO SOL	0.45	Healthcare	FnGuide Medical Device Director Index - KRW - Benchmark Price Return	8/22/2023	9,285.07	2.31	17.09
LS Leverage Shares 2X Long UNH Daily ETF ·	Stocks	123.66 M	1.91 M	LS Leverage Shares	0.77	Healthcare		7/22/2025	9.37	0.00	0.00
IN Invesco S&P SmallCap Health Care ETF ·	Stocks	121.86 M	21,390.46	IN Invesco	0.29	Healthcare	S&P SmallCap 600 Capped Health Care Index - Benchmark TR Gross	4/7/2010	41.38	2.51	19.03
IN Invesco Dorsey Wright Healthcare Momentum ETF ·	Stocks	118.81 M	8,232.71	IN Invesco	0.60	Healthcare	Dorsey Wright Healthcare Tech Leaders TR	10/12/2006	49.73	5.92	26.92
FU Fullgoal Hang Seng Biotechnology ETF Units ·	Stocks	116.43 M	—	FU Fullgoal	0.60	Healthcare	Hang Seng Biotech Index - CNY - Benchmark TR Gross	12/24/2025	1.00	0.00	0.00
CS China Southern All Share Health Care ETF ·	Stocks	114.35 M	—	CS China Southern	0.60	Healthcare	CSI Full Index of Medical and Healthcare Equipment and Service Index - CNY - Benchmark TR Gross	10/22/2021	0.56	2.73	32.82
DE Defiance Daily Target 2X Long LLY ETF ·	Stocks	112.67 M	351,920.7	DE Defiance	1.32	Healthcare		8/7/2024	17.88	0.00	0.00
IS iShares S&P 500 Health Care Sector UCITS ETF ·	Stocks	109.96 M	—	IS iShares	0.18	Healthcare	S&P 500 CAPPED 35/20 HEALTH CARE NTR	6/15/2020	6.66	0.00	0.00
CI CI Health Care Giants Covered Call ETF Trust Units -Hedged- ·	Stocks	105.96 M	—	CI CI	0.83	Healthcare		6/7/2018	10.52	3.88	17.87
TD TD Global Healthcare Leaders Index ETF ·	Stocks	104.66 M	—	TD TD	0.44	Healthcare	Solactive Global Healthcare Leaders Index - CAD - Benchmark TR Net	2/25/2021	18.83	3.51	20.54
HE Harvest Healthcare Leaders Income ETF ·	Stocks	104.2 M	—	HE Harvest ETFs	1.06	Healthcare		1/17/2017	7.83	0.00	0.00
DI Direxion Daily S&P Biotech Bear 3X ETF ·	Stocks	101.54 M	4.12 M	DI Direxion	1.07	Healthcare	S&P Biotechnology Select Industry	5/28/2015	15.81	0.00	0.00
SA Satrix Healthcare Innovation Feeder ETF Accum Units ZAR ·	Stocks	100.55 M	—	SA Satrix	0.48	Healthcare	STOXX Global Breakthrough Healthcare (USD)(NR)	5/26/2022	73.03	0.00	0.00
HE Harvest Healthcare Leaders Enhanced Income ETF Trust Units A ·	Stocks	93.23 M	—	HE Harvest ETFs	2.69	Healthcare		10/25/2022	8.28	0.00	0.00
FM F/M Emerald Life Sciences Innovation ETF ·	Stocks	93.12 M	6,280.61	FM F/m	0.54	Healthcare		10/30/2024	34.94	6.27	0.00
AM Amundi MSCI World Health Care UCITS ETF USD ACC ·	Stocks	90.3 M	—	AM Amundi	0.30	Healthcare	MSCI World Index / Health Care -SEC	8/19/2010	542.98	7.37	31.30
KR KraneShares MSCI All China Health Care Index ETF ·	Stocks	84.92 M	38,651.35	KR KraneShares	0.65	Healthcare	MSCI China All Shares Health Care 10/40 Index	2/1/2018	17.96	3.41	26.60
CI CI Global Healthcare Leaders Index ETF Trust Units -Unhedged- ·	Stocks	82.21 M	—	CI CI	0.56	Healthcare	Solactive Developed Markets Healthcare 150 CAD Index - CAD - Benchmark TR Net	8/17/2021	23.70	0.00	0.00
PR ProShares Ultra Nasdaq Biotechnology ·	Stocks	81.66 M	10,204	PR ProShares	0.95	Healthcare	NASDAQ / Biotechnology	4/7/2010	81.82	0.00	0.00
SP State Street SPDR S&P Health Care Services ETF ·	Stocks	80.79 M	7,181.64	SP SPDR	0.35	Healthcare	S&P Health Care Services Select Industry	9/28/2011	98.47	2.54	15.55
MI Middlefield Healthcare Dividend ETF Trust Units ·	Stocks	80.16 M	—	MI Middlefield	1.42	Healthcare		2/12/2019	10.94	0.00	0.00
CA Guotai GEM Health Care Index ETF Units ·	Stocks	78.35 M	—	CA Cathay	0.00	Healthcare	ChiNext Medical and Healthcare Index - CNY - Benchmark TR Net	4/2/2025	1.07	0.00	0.00
KS KSM ETF (4D) S&P Health Care Units ·	Stocks	78.23 M	—	KS KSM	0.73	Healthcare	S&P Health Care Select Sector	12/4/2018	48.79	0.00	0.00
PR ProShares Ultra Health Care ·	Stocks	74.9 M	10,776.15	PR ProShares	0.95	Healthcare	S&P Health Care Select Sector	1/30/2007	43.84	0.00	0.00
IN Invesco Nasdaq Biotechnology ETF ·	Stocks	71.27 M	26,417.01	IN Invesco	0.19	Healthcare	NASDAQ / Biotechnology	6/11/2021	29.10	4.91	21.12
AM Amundi STOXX Europe 600 Healthcare UCITS ETF Distribution ·	Stocks	69.72 M	—	AM Amundi	0.30	Healthcare	STOXX Europe 600 / Health Care (Capped) - SS	7/2/2020	191.91	2.98	20.61
DE Defiance Daily Target 2X Long HIMS ETF ·	Stocks	68.94 M	32.33 M	DE Defiance	1.29	Healthcare		3/12/2025	19.42	0.00	0.00
BR Brompton Global Healthcare Income & Growth ETF ·	Stocks	63.22 M	—	BR Brompton	1.09	Healthcare		4/3/2018	7.50	6.13	23.54
CH ChinaAMC SSE STAR Biology and Medicine Index ETF Units ·	Stocks	62.41 M	—	CH ChinaAMC	0.00	Healthcare	Shanghai Stock Exchange Science and Technology Innovation Board Biopharmaceutical Index - CNY - Benchmark TR Gross	5/14/2025	1.08	0.00	0.00
FI Fidelity Disruptive Medicine ETF ·	Stocks	57.36 M	6,479.25	FI Fidelity	0.50	Healthcare		6/12/2023	24.72	4.23	37.59
IS iShares NASDAQ US Biotechnology UCITS ETF ·	Stocks	56 M	—	IS iShares	0.35	Healthcare	NASDAQ / Biotechnology	3/6/2018	8.48	4.93	21.38
VI Virtus Biotech ETF ·	Stocks	54.57 M	6,341.1	VI Virtus	0.34	Healthcare	LifeSci Biotechnology Products Index	12/17/2014	83.91	5.54	0.00
RO Roundhill GLP-1 & Weight Loss ETF ·	Stocks	52.97 M	27,629.19	RO Roundhill	0.59	Healthcare		5/21/2024	31.89	4.01	14.05
RG ROBO Global Healthcare Technology and Innovation ETF ·	Stocks	51.41 M	7,854.96	RG ROBO Global	0.68	Healthcare	ROBO Global Healthcare Technology and Innovation ETF	6/25/2019	33.12	3.10	25.46
TE Tema Heart & Health ETF ·	Stocks	51.27 M	7,437.87	TE Tema	0.75	Healthcare		11/21/2023	33.81	6.56	21.55
VA VanEck Global Healthcare Leaders ETF ·	Stocks	50.79 M	—	VA VanEck	0.45	Healthcare	MarketGrader Developed Markets ex-Australia Health Care Index - AUD	9/8/2020	11.35	4.95	21.34
MI Middlefield Health & Wellness ETF Trust Units ·	Stocks	45.61 M	—	MI Middlefield	1.46	Healthcare		10/20/2016	12.47	4.47	21.53
GX Global X S&P Biotech ETF ·	Stocks	40.92 M	—	GX Global X	0.45	Healthcare	S&P Biotechnology Select Industry	11/8/2018	63.08	5.08	0.00
FU Fuguo Guozheng Vaccine & Biotechnology ETF ·	Stocks	40.7 M	—	FU Fullgoal	0.60	Healthcare	CSI Vaccine and Biotechnology Index - CNY - Benchmark TR Gross	9/16/2022	0.66	2.00	29.03
TR Tradr 2X Long TEM Daily ETF ·	Stocks	38.91 M	498,586.1	TR Tradr	1.30	Healthcare		5/12/2025	15.86	0.00	0.00
IS iShares Evolved US Innovative Healthcare ETF ·	Stocks	37.57 M	3,240.71	IS iShares	0.18	Healthcare		3/21/2018	34.58	5.85	16.28
DE Defiance Daily Target 2X Long NVO ETF ·	Stocks	37.16 M	953,557.6	DE Defiance	1.30	Healthcare		12/3/2024	10.29	0.00	0.00
IS iShares Evolved US Healthcare Staples ETF ·	Stocks	36.66 M	7,601.91	IS iShares	0.18	Healthcare		3/21/2018	41.34	4.27	23.49
PU Unitedhealth Group Unh Yield Shares Purpose ETF ·	Stocks	36.24 M	—	PU Purpose	0.00	Healthcare		2/7/2025	7.98	0.00	0.00
VI Virtus Biotech Clinical Trials ETF ·	Stocks	35.94 M	19,704.68	VI Virtus	0.65	Healthcare	LifeSci Biotechnology Clinical Trials Index	12/16/2014	42.83	4.22	0.00
EV Evolve Global Healthcare Enhanced Yield Fund ·	Stocks	32.67 M	—	EV Evolve	0.72	Healthcare	Solactive Global Healthcare 20 Index - CAD	10/25/2017	22.60	0.00	0.00
TA Tachlit SAL 4D NASDAQ Biotechnology ETF ·	Stocks	31.72 M	—	TA Tachlit	1.23	Healthcare	NASDAQ / Biotechnology	11/13/2018	152.42	0.00	0.00
HE Harvest Eli Lilly High Income Shares ETF ·	Stocks	30.63 M	—	HE Harvest ETFs	0.00	Healthcare		8/21/2024	9.22	0.00	0.00
YI YieldMax HIMS Option Income Strategy ETF ·	Stocks	29.47 M	59,230.09	YI YieldMax	1.01	Healthcare		9/22/2025	13.06	0.00	0.00
FT First Trust Nasdaq Pharmaceuticals ETF ·	Stocks	29.34 M	8,405.43	FT First Trust	0.60	Healthcare	Nasdaq US Smart Pharmaceuticals Index	9/20/2016	34.17	4.73	18.68
BM BMO Covered Call Health Care ETF CAD Units Trust Unit ·	Stocks	28.21 M	—	BM BMO	0.78	Healthcare		1/23/2023	26.39	4.17	22.59
HA Harbor Health Care ETF ·	Stocks	27.53 M	5,726.47	HA Harbor	0.80	Healthcare		11/17/2022	29.65	11.65	33.30
HA Hanwha ARIRANG KRX300 Health Care ETF ·	Stocks	25.99 M	—	HA Hanwha	0.40	Healthcare	KRX 300 Healthcare Index - KRW - Benchmark TR Gross	11/8/2018	7,972.52	4.05	49.35
XT Xtrackers MSCI Global SDG 3 Good Health UCITS ETF ·	Stocks	25.41 M	—	XT Xtrackers	0.35	Healthcare	MSCI ACWI IMI SDG 3 Good Health and Well-being Select Index - Benchmark TR Net	1/18/2023	35.36	4.42	20.67
GX Global X HealthTech ETF ·	Stocks	23.89 M	14,861.33	GX Global X	0.50	Healthcare	Global X HealthTech Index - Benchmark TR Net	7/29/2020	23.83	3.67	26.47
JH John Hancock Multifactor Healthcare ETF ·	Stocks	23.44 M	12,449.4	JH John Hancock	0.40	Healthcare	John Hancock Dimensional Healthcare Index	9/29/2015	44.40	4.05	17.36
SM Smart Healthcare Innovation ETF ·	Stocks	23.08 M	—	SM Smart	0.75	Healthcare	STOXX Global Breakthrough Healthcare (USD)(NR)	6/6/2019	3.37	0.00	0.00
GS Future Health Care Equity ETF ·	Stocks	21.42 M	2,982.19	GS Goldman Sachs	0.75	Healthcare		11/9/2021	32.93	7.30	29.06
AD AdvisorShares Psychedelics ETF ·	Stocks	20.63 M	11,529.15	AD AdvisorShares	1.00	Healthcare		9/15/2021	17.40	3.48	0.00
FU Founder Fubon CSI Health Care Innovation Index Exchange Traded Fund Units ·	Stocks	20.48 M	—	FU Fubon	0.60	Healthcare	CSI Pharmaceutical and Medical Device Innovation Index - CNY - Benchmark TR Gross	3/3/2022	0.69	0.00	0.00

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