ETF · Segment

Healthcare

Total ETFs

389

All Products

389 ETFs

Name	Asset class	AUM	Durch. Volume	Provider	Expense Ratio	Investment Segment	Index	Launch date	NAV (Net Asset Value)	P/B	P/E
LG Legal & General UCITS ETF Plc - Pharma Breakthrough ·	Stocks	19.63 M	—	LG L&G	0.49	Healthcare	Solactive Pharma Breakthrough Value Index	1/23/2018	13.72	3.62	18.36
LG Legal & General UCITS ETF Plc - Pharma Breakthrough ·	Stocks	19.63 M	—	LG L&G	0.49	Healthcare	Solactive Pharma Breakthrough Value Index	1/23/2018	13.72	3.62	18.36
BO Bosera CSI Vaccine and Biotechnology ETF ·	Stocks	19.56 M	—	BO Bosera	0.60	Healthcare	CSI Vaccine and Biotechnology Index - CNY - Benchmark TR Gross	11/8/2022	0.52	0.00	0.00
TR T. Rowe Price Health Care ETF ·	Stocks	18.53 M	2,990.98	TR T. Rowe Price	0.44	Healthcare		6/11/2025	27.65	3.97	25.60
HK Horizon Kinetics Medical ETF ·	Stocks	18.35 M	2,359.58	HK Horizon Kinetics	0.85	Healthcare		1/30/2023	33.35	5.70	22.16
DI Direxion Daily LLY Bull 2X ETF ·	Stocks	18.24 M	119,403.6	DI Direxion	1.07	Healthcare		3/26/2025	19.99	0.00	0.00
PR Principal Healthcare Innovators ETF ·	Stocks	16.16 M	11,182.75	PR Principal	0.42	Healthcare	BTEC-US - No Underlying Index	8/19/2016	39.41	4.34	0.00
BM BMO SPDR Health Care Select Sector Index ETF ·	Stocks	15.75 M	—	BM BMO	0.00	Healthcare	S&P Health Care Select Sector	1/21/2025	28.20	0.00	0.00
IN Invesco S&P World Health Care ESG UCITS ETF AccumUSD ·	Stocks	15.19 M	—	IN Invesco	0.18	Healthcare	S&P Developed Ex-Korea LargeMidCap ESG Enhanced Health Care Index - Benchmark TR Net	4/12/2023	6.21	4.97	23.13
HA Harbor Health Care UCITS ETF Accum Shs -A- USD ·	Stocks	14.63 M	—	HA HANetf	0.59	Healthcare	Indxx Advanced Life Sciences & Smart Healthcare Thematic Index	4/4/2019	7.33	9.44	30.16
HE Harvest Healthcare Leaders Income ETF Trust Units B Unhedged ·	Stocks	14.46 M	—	HE Harvest ETFs	1.06	Healthcare		2/27/2020	8.37	0.00	0.00
TA Tachlit SAL (4D) S&P Health Care ·	Stocks	13.45 M	—	TA Tachlit	0.50	Healthcare	S&P Health Care Select Sector	11/13/2018	171.70	0.00	0.00
SP State Street Health Care Select Sector SPDR Premium Income ETF ·	Stocks	12.73 M	10,560.29	SP SPDR	0.35	Healthcare	S&P Health Care Select Sector	7/29/2025	24.57	0.00	0.00
EV Evolve Global Healthcare Enhanced Yield Fund Trust Units USD Unhedged ·	Stocks	12.41 M	—	EV Evolve	0.72	Healthcare	Solactive Global Healthcare 20 Index - Benchmark TR Net	11/27/2019	18.28	0.00	0.00
RO Roundhill UNH WeeklyPay ETF ·	Stocks	12.03 M	5,559.98	RO Roundhill	0.99	Healthcare		12/3/2025	38.27	0.00	0.00
FT First Trust NYSE Arca Biotechnology UCITS ETF ·	Stocks	11.79 M	—	FT First Trust	0.60	Healthcare	NYSE Arca Biotechnology Index	5/27/2020	24.75	3.45	22.71
FT First Trust NYSE Arca Biotechnology UCITS ETF ·	Stocks	11.79 M	—	FT First Trust	0.60	Healthcare	NYSE Arca Biotechnology Index	5/27/2020	24.75	3.45	22.71
DI Direxion Daily Pharmaceutical & Medical Bull 3X ETF ·	Stocks	11.69 M	106,486.3	DI Direxion	0.98	Healthcare	S&P Pharmaceuticals Select Industry	11/15/2017	10.60	0.00	0.00
JP JPMorgan Healthcare Leaders ETF ·	Stocks	11.17 M	926	JP JPMorgan	0.65	Healthcare		11/1/2023	55.58	4.96	22.26
TA Tachlit SAL (4A) S&P Health Care Currency-Hedged ·	Stocks	10.99 M	—	TA Tachlit	0.83	Healthcare	S&P Health Care Select Sector	11/27/2018	43.73	0.00	0.00
VA VanEck UCITS ETFs PLC - VanEck Medical Robotics and Bionic Engineering UCITS ETF Accum A USD ·	Stocks	10.61 M	—	VA VanEck	0.00	Healthcare	MVIS Global Bionic Healthcare ESG Index - Benchmark TR Net	12/2/2022	18.52	3.60	27.00
IS iShares Health Innovation Active ETF ·	Stocks	10.44 M	3,865.58	IS iShares	0.55	Healthcare		9/29/2020	28.91	4.69	23.25
TE Tema Neuroscience and Mental Health ETF ·	Stocks	10.28 M	107.38	TE Tema	0.75	Healthcare		1/22/2024	23.79	3.94	29.55
AM Amplify Treatments, Testing and Advancements ETF ·	Stocks	9.67 M	2,195.5	AM Amplify	0.68	Healthcare	Prime Treatments, Testing and Advancements Index - USD	6/17/2020	19.34	2.17	13.17
BM BMO Equal Weight US Health Care Index ETF CAD Units Trust Units ·	Stocks	9.44 M	—	BM BMO	0.40	Healthcare	Solactive Equal Weight U.S Health Care Index - CAD	2/15/2019	41.68	3.68	20.81
HO Horizons Psychedelic Stock Index ETF Trust Units A ·	Stocks	9.26 M	—	HO Horizons	1.63	Healthcare	North American Psychedelics Index - CAD	1/26/2021	6.58	1.92	0.00
IT IT Now Morningstar XT US Healthcare Fundo de Indice ·	Stocks	9.1 M	—	IT Itau	0.00	Healthcare	Morningstar US Exponential Technologies Healthcare Index - Benchmark TR Gross	6/9/2021	55.41	3.89	24.16
GX Global X MSCI China Health Care ETF ·	Stocks	8.7 M	2,907.8	GX Global X	0.65	Healthcare	MSCI China Health Care 10-50	12/7/2018	13.17	2.24	15.02
FI Fidelity Digital Health ETF ·	Stocks	8.23 M	1,896.42	FI Fidelity	0.40	Healthcare	Fidelity Digital Health Index	10/5/2021	20.68	3.85	37.90
BM BMO Global Health Care Fund Trust Units Series -Active ETF- ·	Stocks	8.13 M	—	BM BMO	0.00	Healthcare		6/26/2023	18.04	0.00	0.00
IN Invesco STOXX Europe 600 Optimised Health Care UCITS ETF ·	Stocks	7.87 M	—	IN Invesco	0.20	Healthcare	STOXX Europe 600 Optimised Health Care Index - EUR	7/8/2009	397.47	3.50	20.50
DE Defiance Nasdaq Junior Biotechnology ETF ·	Stocks	7.48 M	2,408.21	DE Defiance	0.45	Healthcare	NASDAQ Junior Biotechnology Index	8/3/2020	29.93	5.24	0.00
IN Investo S&P Biotechnology Selection Industry ETF Fundo de Investimento de Indice - Investimento no Exterior ·	Stocks	7.27 M	—	IN Investo	0.00	Healthcare	S&P Biotechnology Select Industry	12/15/2021	59.86	0.00	0.00
RA Range Cancer Therapeutics ETF ·	Stocks	6.95 M	1,989.8	RA Range	0.79	Healthcare	Range Oncology Therapeutics Index	10/13/2015	8.90	1.22	0.00
FT First Trust AlphaDEX US Health Care Sector Index ETF ·	Stocks	6.19 M	—	FT First Trust	0.80	Healthcare	StrataQuant Health Care Index	10/29/2014	41.32	3.02	17.23
IS iShares Genomics Immunology and Healthcare Index ETF Trust Units ·	Stocks	6.17 M	—	IS iShares	0.47	Healthcare	NYSE FactSet Global Genomics and Immuno Biopharma Index	4/26/2022	40.42	2.86	14.62
MU Mulvihill U.S. Health Care Enhanced Yield ETF ·	Stocks	5.07 M	—	MU Mulvihill	0.00	Healthcare		1/31/2023	7.73	4.06	25.89
DE Defiance Next Gen Altered Experience ETF ·	Stocks	5.04 M	6,192.89	DE Defiance	0.75	Healthcare		5/27/2021	5.93	0.00	0.00
IS iShares Neuroscience and Healthcare ETF ·	Stocks	4.99 M	1,153.05	IS iShares	0.47	Healthcare	NYSE FactSet Global Neuro Biopharma and MedTech Index	8/24/2022	33.22	4.64	16.48
GX Global X Telemedicine & Digital Health UCITS ETF Accum Shs USD ·	Stocks	4.91 M	—	GX Global X	1.20	Healthcare	Solactive Telemedicine & Digital Health Index- TR Net	12/17/2020	7.54	3.22	29.60
CI Circa5000 Health & Wellbeing Ucits ETF AccumUSD ·	Stocks	4.66 M	—	CI CIRCA5000	0.49	Healthcare	Impak CIRCA5000 Health & Wellbeing Impact Index - Benchmark TR Net	6/5/2023	5.22	0.00	0.00
BM BMO SPDR Health Care Select Sector Index ETF Hedged ·	Stocks	4.36 M	—	BM BMO	0.00	Healthcare	S&P Health Care Select Sector	1/21/2025	28.54	0.00	0.00
HE Harvest Eli Lilly Enhanced High Income Shares ETF USD ·	Stocks	4.34 M	—	HE Harvest ETFs	0.00	Healthcare		8/21/2024	8.09	0.00	0.00
CI CI Health Care Giants Covered Call ETF ·	Stocks	4.3 M	—	CI CI	0.84	Healthcare		6/7/2018	12.29	0.00	0.00
AM Amplify Weight Loss Drug & Treatment ETF ·	Stocks	4.17 M	3,176.79	AM Amplify	0.59	Healthcare	VettaFi Weight Loss Drug & Treatment Index - Benchmark TR Net	5/21/2024	24.07	5.28	19.73
KS KSM ETF (4D) STOXX Europe 600 Health Care Units ·	Stocks	4.16 M	—	KS KSM	0.00	Healthcare	STOXX Europe 600 / Health Care (Capped) - SS	11/20/2018	429.28	0.00	0.00
LO Loncar China BioPharma ETF ·	Stocks	4.03 M	470.64	LO Loncar	0.79	Healthcare	Loncar China BioPharma	8/14/2018	14.88	1.73	12.13
PR ProShares UltraShort Health Care ·	Stocks	4 M	14,883.49	PR ProShares	0.95	Healthcare	S&P Health Care Select Sector	1/30/2007	10.59	0.00	0.00
AN Apex Healthcare ETF ·	Stocks	3.98 M	9,586.47	AN Anfield	0.95	Healthcare	MarketGrader Global Health Care Leaders Index	9/21/2021	8.91	4.00	12.63
HE Harvest Novo Enhanced High Income Shares ETF Trust Units A ·	Stocks	3.96 M	—	HE Harvest ETFs	0.00	Healthcare		1/15/2026	6.46	0.00	0.00
TR Tradr 2X Long SRPT Daily ETF ·	Stocks	3.96 M	35,128.46	TR Tradr	1.30	Healthcare		10/22/2025	10.41	0.00	0.00
FT First Trust NYSE Arca Biotechnology ETF Trust Units ·	Stocks	3.89 M	—	FT First Trust	0.73	Healthcare	NYSE Arca Biotechnology Index	2/17/2021	35.32	28.29	30.59
AD Novo Nordisk A/S (B Shares) ADRhedged ·	Stocks	3.86 M	6,199.71	AD ADRhedged	0.19	Healthcare		1/7/2025	20.68	0.00	0.00
GR GraniteShares 3x Long Moderna Daily ETP Securities - Cap USD - Ireland ·	Stocks	3.81 M	—	GR GraniteShares	5.20	Healthcare	Solactive Daily Leveraged 3x long Moderna Index - Benchmark TR Net	8/30/2021	39.83	0.00	0.00
RS REX LLY Growth & Income ETF 3Shs ·	Stocks	3.8 M	8,022.96	RS REX Shares	0.99	Healthcare		11/4/2025	22.05	0.00	0.00
LA Langar Global HealthTech ETF ·	Stocks	3.47 M	2,123.55	LA Langar	0.85	Healthcare		1/10/2024	8.63	3.48	25.34
TD TD Global Healthcare Leaders Index ETF Trust Units ·	Stocks	3.46 M	—	TD TD	0.45	Healthcare	Solactive Global Healthcare Leaders Index	5/2/2022	13.66	0.00	0.00
GX Global X Health Care Covered Call & Growth ETF ·	Stocks	3.44 M	643.57	GX Global X	0.60	Healthcare	Cboe S&P Health Care Select Sector Half BuyWrite Index - Benchmark TR Gross	11/21/2022	24.54	5.04	27.46
DI Direxion Daily Biotech Top 5 Bull 2X ETF ·	Stocks	3.05 M	743.82	DI Direxion	0.98	Healthcare	NYSE Biotechnology Top 5 Equal Weight Index - Benchmark TR Gross	10/1/2025	29.23	0.00	0.00
DI Direxion mRNA ETF ·	Stocks	3.02 M	2,823.16	DI Direxion	0.65	Healthcare	BITA Messenger RNA Technology Index - Benchmark TR Net	12/9/2021	13.76	3.69	0.00
GR GraniteShares 2x Long ISRG Daily ETF ·	Stocks	2.93 M	6,209.94	GR GraniteShares	1.50	Healthcare		10/7/2025	23.07	0.00	0.00
FI Fidelity Digital Health UCITS ETF Accum USD ·	Stocks	2.89 M	—	FI Fidelity	0.50	Healthcare	Fidelity Digital Health ESG Tilted Index - Benchmark TR Net	8/24/2022	5.42	0.00	0.00
FT First Trust AlphaDEX US Health Care Sector Index ETF ·	Stocks	2.88 M	—	FT First Trust	0.82	Healthcare	StrataQuant Health Care Index - CAD	12/8/2017	28.81	0.00	0.00
DI Direxion Daily LLY Bear 1X ETF ·	Stocks	2.84 M	17,809.32	DI Direxion	1.01	Healthcare	Eli Lilly and Co. - USD - Benchmark Price Return	3/26/2025	19.31	0.00	0.00
TA Tachlit SAL (4A) NASDAQ Biotechnology Currency-Hedged ·	Stocks	2.78 M	—	TA Tachlit	0.30	Healthcare	NASDAQ / Biotechnology	11/27/2018	30.55	0.00	0.00
DE Defiance Leveraged Long Income HIMS ETF ·	Stocks	2.75 M	39,400.93	DE Defiance	1.51	Healthcare		8/18/2025	5.17	0.00	0.00
GX Global X Equal Weight Global Healthcare Index ETF Trust Unit A ·	Stocks	2.71 M	—	GX Global X	0.00	Healthcare	VettaFi Equal Weight Global Healthcare Index - CAD - Benchmark TR Net	4/30/2025	21.64	0.00	0.00
FR Franklin Future Of Health And Wellness Ucits ETF AccumUSD ·	Stocks	2.63 M	—	FR Franklin	0.30	Healthcare	Solactive Sustainable Health and Wellness Index	7/5/2023	27.13	3.22	18.08
FR Franklin Future Of Health And Wellness Ucits ETF AccumUSD ·	Stocks	2.63 M	—	FR Franklin	0.30	Healthcare	Solactive Sustainable Health and Wellness Index	7/5/2023	27.13	3.22	18.08
FR Franklin Future Of Health And Wellness Ucits ETF AccumUSD ·	Stocks	2.63 M	—	FR Franklin	0.30	Healthcare	Solactive Sustainable Health and Wellness Index	7/5/2023	27.13	3.22	18.08
FT First Trust Nasdaq Lux Digital Health Solutions ETF ·	Stocks	2.45 M	381.93	FT First Trust	0.65	Healthcare	NASDAQ Lux Health Tech Index	3/22/2022	16.35	4.66	26.17
PR ProShares UltraShort Nasdaq Biotechnology ·	Stocks	2.45 M	14,809.44	PR ProShares	0.95	Healthcare	NASDAQ / Biotechnology	4/7/2010	8.77	0.00	0.00
CI CI Health Care Giants Covered Call ETF Trust Units -USD Hedged- ·	Stocks	2.33 M	—	CI CI	0.85	Healthcare		3/3/2022	9.28	0.00	0.00
KE Kelly CRISPR & Gene Editing Technology ETF ·	Stocks	2.1 M	2,437.82	KE Kelly	0.78	Healthcare	Strategic CRISPR & Gene Editing Technology Index - Benchmark TR Gross	1/12/2022	7.02	1.68	17.02
HO Horizons Global Vaccines and Infectious Diseases Index ETF Trust Units A ·	Stocks	2.03 M	—	HO Horizons	1.19	Healthcare	Solactive Global Vaccines and Infectious Diseases Index - CAD - Benchmark TR Net	10/26/2021	15.47	0.00	0.00
HE Harvest JnJ Enhanced High Income Shares ETF Trust Unit A ·	Stocks	2.03 M	—	HE Harvest ETFs	0.00	Healthcare		1/15/2026	13.49	0.00	0.00
LS Leverage Shares 3x Long Moderna ETP ·	Stocks	1.97 M	—	LS Leverage Shares	3.78	Healthcare	iSTOXX Leveraged 3x MRNA Index - Benchmark TR Net	12/14/2021	18.28	0.00	0.00
KR KraneShares Emerging Markets Healthcare Index ETF ·	Stocks	1.97 M	1,458.16	KR KraneShares	0.81	Healthcare	Solactive Emerging Markets Healthcare Index NTR	8/29/2018	19.78	3.09	26.95
PU Purpose Healthcare Innovation Yield Fund ·	Stocks	1.93 M	—	PU Purpose	1.27	Healthcare		10/4/2021	19.26	4.48	18.17
FT First Trust Indxx Medical Devices ETF ·	Stocks	1.91 M	174	FT First Trust	0.70	Healthcare	Indxx Global Medical Equipment Index	6/22/2021	19.07	2.93	26.01
PS PSYK ETF ·	Stocks	1.9 M	994.96	PS PSYK	0.75	Healthcare	Enhanced Consciousness Index - Benchmark TR Net	1/31/2022	17.31	2.18	0.00
GX Global X China Biotech Innovation ETF ·	Stocks	1.73 M	1,413.66	GX Global X	0.65	Healthcare	Solactive China Biotech Innovation Index	9/22/2020	7.51	2.41	18.61
BE Betashares Digital Health and Telemedicine ETF Exchange Traded Fund Units ·	Stocks	1.68 M	—	BE BetaShares	0.67	Healthcare	Nasdaq CTA Global Digital Health Index - AUD - Benchmark TR Net	3/30/2022	10.54	3.36	39.43
KR KraneShares MSCI All China Health Care Index UCITS ETF AccumUSD ·	Stocks	1.5 M	—	KR KraneShares	0.65	Healthcare	MSCI China All Shares Health Care 10/40 Index	1/14/2021	9.98	2.55	19.00
DE Defiance Daily Target 2X Short LLY ETF ·	Stocks	1.48 M	84,832.41	DE Defiance	1.29	Healthcare		9/2/2025	8.55	0.00	0.00
HE Harvest Eli Lilly High Income Shares ETF USD ·	Stocks	1.37 M	—	HE Harvest ETFs	0.00	Healthcare		8/21/2024	8.98	0.00	0.00
AD AstraZeneca PLC ADRhedged ·	Stocks	1.1 M	6,395.88	AD ADRhedged	0.19	Healthcare	AstraZeneca PLC - Benchmark Price Return	10/1/2024	54.92	0.00	0.00
HO Horizons GX Telemedicine and Digital Health Index ETF Trust Units A ·	Stocks	1.1 M	—	HO Horizons	0.89	Healthcare	Solactive Telemedicine & Digital Health Index- TR Net	11/2/2021	18.30	0.00	0.00
BM BMO Covered Call Health Care ETF Target Cash Flow Units Trust Units ·	Stocks	1.09 M	—	BM BMO	0.00	Healthcare		2/9/2026	42.86	0.00	0.00
DE Defiance Daily Target 2X Long MRNA ETF ·	Stocks	1.02 M	12,108.85	DE Defiance	1.31	Healthcare		2/3/2026	24.56	0.00	0.00
BR Brompton Global Healthcare Income & Growth ETF USD Trust Unit ·	Stocks	962,707.75	—	BR Brompton	1.09	Healthcare		8/8/2019	11.66	0.00	0.00
AI AXS 2X PFE Bear Daily ETF ·	Stocks	865,180.5	356.09	AI AXS Investments	1.15	Healthcare	Pfizer Inc.	7/14/2022	58.55	0.00	0.00
GR GraniteShares YieldBoost HIMS ETF ·	Stocks	845,907.7	7,032.45	GR GraniteShares	1.07	Healthcare		12/2/2025	7.45	0.00	0.00
AD GSK plc ADRhedged ·	Stocks	789,078.9	440.68	AD ADRhedged	0.19	Healthcare	GSK plc - Benchmark Price Return	1/7/2025	80.36	0.00	0.00
GR GraniteShares 3x Short Moderna Daily ETP ·	Stocks	706,216.1	—	GR GraniteShares	0.99	Healthcare	Solactive Daily Leveraged 3x short Moderna Index - EUR - Benchmark TR Net	8/30/2021	3.76	0.00	0.00
GR GraniteShares 3x Long Astrazeneca Daily ETP ·	Stocks	656,690.2	—	GR GraniteShares	2.39	Healthcare	Solactive Daily Leveraged 3x long BP Index	11/4/2019	53.47	0.00	0.00
LS Leverage Shares 2X Long CNC Daily ETF ·	Stocks	654,524	3,930.1	LS Leverage Shares	0.75	Healthcare		12/18/2025	10.74	0.00	0.00
SU Subversive Mental Health ETF ·	Stocks	603,747.5	286.64	SU Subversive	0.76	Healthcare		12/23/2022	24.15	4.55	28.50
WE WEBs Health Care XLV Defined Volatility ETF ·	Stocks	585,416	654.36	WE WEBs	0.89	Healthcare	Syntax Defined Volatility XLV Index - Benchmark TR Net	7/23/2025	29.05	0.00	0.00
LS Leverage Shares 3X Long UnitedHealth UNH ETP Securities ·	Stocks	523,454.53	—	LS Leverage Shares	0.00	Healthcare	Euronext 3x Long UnitedHealth Index - Benchmark TR Net	9/16/2025	6.65	0.00	0.00

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