10,03904 % | Bain Capital Life Sciences Investors, LLC | 16.915.784 | 955.196 | 31/12/2023 |
8,89424 % | New Enterprise Associates (NEA) | 14.986.793 | 0 | 31/12/2023 |
4,75304 % | The Vanguard Group, Inc. | 8.008.865 | 184.148 | 31/12/2023 |
4,61187 % | BlackRock Institutional Trust Company, N.A. | 7.771.007 | 260.683 | 31/12/2023 |
4,23354 % | OrbiMed Advisors, LLC | 7.133.515 | 0 | 31/12/2023 |
2,53787 % | Adage Capital Management, L.P. | 4.276.315 | 0 | 31/12/2023 |
2,12963 % | Sio Capital Management, LLC | 3.588.427 | 989.424 | 31/12/2023 |
2,10413 % | Perceptive Advisors LLC | 3.545.454 | 0 | 31/12/2023 |
2,06153 % | Kingdon Capital Management, L.L.C. | 3.473.683 | 1.500.000 | 31/12/2023 |
1,82405 % | AXA Investment Managers UK Ltd. | 3.073.532 | -74.333 | 31/12/2023 |
1,80800 % | Acorn Bioventures L.P. | 3.046.472 | 0 | 31/12/2023 |
1,66317 % | Geode Capital Management, L.L.C. | 2.802.449 | 159.534 | 31/12/2023 |
1,63578 % | Medical Strategy GmbH | 2.756.296 | 0 | 31/12/2023 |
1,44082 % | State Street Global Advisors (US) | 2.427.789 | 49.163 | 31/12/2023 |
1,14896 % | Armistice Capital LLC | 1.936.000 | -420.000 | 31/12/2023 |
1,03444 % | UBS O'Connor LLC | 1.743.038 | 183.052 | 31/12/2023 |
1,02556 % | Citadel Advisors LLC | 1.728.065 | -70.563 | 31/12/2023 |
0,98773 % | Millennium Management LLC | 1.664.317 | -1.951.647 | 31/12/2023 |
0,57351 % | Northern Trust Investments, Inc. | 966.363 | 4792 | 31/12/2023 |
0,56093 % | GSA Capital Partners LLP | 945.171 | 323.584 | 31/12/2023 |
0,45539 % | Parkman Healthcare Partners LLC | 767.332 | -32.668 | 31/12/2023 |
0,38576 % | Point72 Asset Management, L.P. | 650.000 | 0 | 31/12/2023 |
0,35992 % | Ragan (Paula) | 606.464 | -49.678 | 11/3/2024 |
0,32599 % | Schonfeld Strategic Advisors LLC | 549.300 | -36.742 | 31/12/2023 |
0,31751 % | Propel Bio Management, LLC | 535.000 | 135.000 | 31/12/2023 |
0,31430 % | Barclays Bank PLC | 529.601 | 147.467 | 31/12/2023 |
0,26001 % | Nuveen LLC | 438.114 | 0 | 31/12/2023 |
0,23912 % | Susquehanna International Group, LLP | 402.921 | 297.714 | 31/12/2023 |
0,23739 % | Simplify Asset Management Inc | 400.000 | 0 | 31/12/2023 |
0,23048 % | Royce Investment Partners | 388.363 | 269.357 | 31/12/2023 |
0,20846 % | BlackRock Investment Management, LLC | 351.262 | 0 | 31/12/2023 |
0,20605 % | Morgan Stanley & Co. LLC | 347.188 | 275.251 | 31/12/2023 |
0,19881 % | New Leaf Venture Partners LLC | 335.000 | 0 | 31/12/2023 |
0,19219 % | Charles Schwab Investment Management, Inc. | 323.843 | 0 | 31/12/2023 |
0,18486 % | SV Health Investors, LLC | 311.490 | 0 | 30/9/2022 |
0,17523 % | BlackRock Financial Management, Inc. | 295.255 | 0 | 31/12/2023 |
0,17477 % | BNY Mellon Asset Management | 294.492 | -128.739 | 31/12/2023 |
0,16828 % | BNP Paribas Securities Corp. North America | 283.544 | 236.899 | 31/12/2023 |
0,13905 % | Taveras (Arthur PhD) | 234.301 | -14.235 | 11/3/2024 |
0,13531 % | Mostafa (Adam S.) | 228.004 | 222.587 | 31/10/2023 |
0,12634 % | BofA Global Research (US) | 212.888 | -160.305 | 31/12/2023 |
0,12292 % | Dibiase (Mary) | 207.128 | -15.409 | 11/3/2024 |
0,10778 % | Acadian Asset Management LLC | 181.609 | 181.609 | 31/12/2023 |
0,09753 % | AQR Capital Management, LLC | 164.342 | 103.053 | 31/12/2023 |
0,09518 % | Rhumbline Advisers Ltd. Partnership | 160.370 | 0 | 31/12/2023 |
0,08497 % | Stewart (Murray) | 143.170 | 139.837 | 10/8/2023 |
0,07672 % | Jane Street Capital, L.L.C. | 129.274 | 115.907 | 31/12/2023 |
0,07580 % | Virtu Americas LLC | 127.718 | 127.718 | 31/12/2023 |
0,07080 % | Knott Partners Management, LLC | 119.300 | 119.300 | 31/12/2023 |
0,05734 % | Northern Trust Global Investments | 96.622 | -9500 | 31/12/2023 |
0,05368 % | Stifel, Nicolaus & Company, Incorporated | 90.452 | 10.174 | 31/12/2023 |
0,05341 % | Woods (Keith) | 90.000 | 90.000 | 16/10/2023 |
0,04825 % | Amundi Asset Management, SAS | 81.305 | 0 | 31/12/2023 |
0,04736 % | JPMorgan Private Bank (United States) | 79.805 | 79.805 | 31/12/2023 |
0,04352 % | Wyzga (Michael S) | 73.333 | 25.000 | 18/8/2023 |
0,04200 % | Group One Trading, L.P. | 70.764 | -155.597 | 31/12/2023 |
0,04100 % | XTX Markets LLC | 69.086 | 69.086 | 31/12/2023 |
0,03844 % | Squarepoint Capital LLP | 64.763 | 64.763 | 31/12/2023 |
0,03632 % | SunAmerica Asset Management, LLC | 61.198 | -247 | 31/12/2023 |
0,03282 % | Dimensional Fund Advisors, L.P. | 55.296 | 0 | 31/12/2023 |
0,03243 % | Invesco Advisers, Inc. | 54.649 | 1620 | 31/12/2023 |
0,03159 % | Morgan Stanley Smith Barney LLC | 53.235 | 10.800 | 31/12/2023 |
0,03059 % | New York State Common Retirement Fund | 51.551 | -417 | 31/12/2023 |
0,03054 % | Mellon Investments Corporation | 51.462 | 0 | 31/12/2023 |
0,02923 % | Voya Investment Management LLC | 49.260 | 0 | 31/12/2023 |
0,02868 % | Aliski (William) | 48.333 | 45.000 | 13/6/2023 |
0,02868 % | Lawton (Alison Frances) | 48.333 | 45.000 | 13/6/2023 |
0,02868 % | Bridger (Gary J) | 48.333 | 45.000 | 13/6/2023 |
0,02868 % | McGirr (David W J) | 48.333 | 45.000 | 13/6/2023 |
0,02868 % | de (Craecker Francoise) | 48.333 | 45.000 | 13/6/2023 |
0,02829 % | SG Americas Securities, L.L.C. | 47.668 | 13.328 | 31/12/2023 |
0,02754 % | Goldman Sachs & Company, Inc. | 46.404 | 26.689 | 31/12/2023 |
0,02711 % | AllianceBernstein L.P. | 45.680 | 0 | 31/12/2023 |
0,02671 % | Bank Vontobel AG | 45.000 | 0 | 31/12/2023 |
0,02671 % | CIBC Private Wealth Management | 45.000 | 0 | 31/12/2023 |
0,02479 % | Invesco Capital Management LLC | 41.777 | 13.777 | 31/12/2023 |
0,02338 % | Bayesian Capital Management, LP | 39.400 | 39.400 | 31/12/2023 |
0,02079 % | Wells Fargo Bank, N.A. | 35.024 | 7396 | 31/12/2023 |
0,01898 % | Florida State Board of Administration | 31.979 | 31.979 | 31/12/2023 |
0,01790 % | PNC Investments LLC | 30.158 | -192 | 31/12/2023 |
0,01758 % | Walleye Capital LLC | 29.616 | 29.616 | 31/12/2023 |
0,01590 % | T. Rowe Price International Ltd | 26.793 | 0 | 31/12/2023 |
0,01566 % | Goldman Sachs Asset Management, L.P. | 26.384 | -3494 | 31/12/2023 |
0,01559 % | RBC Wealth Management, International | 26.264 | 8221 | 31/12/2023 |
0,01531 % | OneDigital Investment Advisors LLC | 25.801 | -4514 | 31/12/2023 |
0,01490 % | Commonwealth Financial Network | 25.100 | -1650 | 31/12/2023 |
0,01473 % | Vaughan Nelson Investment Management, L.P. | 24.819 | 0 | 31/12/2023 |
0,01465 % | Baldry (Mark) | 24.690 | -10.257 | 1/11/2023 |
0,01294 % | Private Advisor Group LLC | 21.800 | 0 | 31/12/2023 |
0,01209 % | ProShare Advisors LLC | 20.378 | 4383 | 31/12/2023 |
0,01203 % | California State Teachers Retirement System | 20.265 | -6902 | 31/12/2023 |
0,01060 % | Bleichroeder LP | 17.865 | 0 | 31/12/2023 |
0,01046 % | Citi Investment Research (US) | 17.630 | 17.562 | 31/12/2023 |
0,01014 % | HRT Financial LP | 17.084 | 17.084 | 31/12/2023 |
0,01014 % | Victory Capital Management Inc. | 17.079 | 3348 | 31/12/2023 |
0,00987 % | Principal Global Investors (Equity) | 16.626 | 299 | 31/12/2023 |
0,00950 % | Lexaurum Advisors, LLC | 16.000 | 0 | 31/3/2024 |
0,00890 % | Grimes & Company, Inc. | 15.000 | 0 | 31/3/2024 |
0,00836 % | Amalgamated Bank Institutional Asset Management & Custody | 14.086 | -1235 | 31/12/2023 |
0,00790 % | Mackenzie Financial Corporation | 13.316 | -50 | 31/12/2023 |