11,56398 % | Redmile Group, LLC | 13.169.057 | 0 | 30/6/2024 |
9,26086 % | The Vanguard Group, Inc. | 10.546.272 | 635.265 | 30/6/2024 |
6,86996 % | BlackRock Institutional Trust Company, N.A. | 7.823.516 | 943.452 | 30/6/2024 |
4,89340 % | Deep Track Capital LP | 5.572.607 | 0 | 30/6/2024 |
4,68800 % | State Street Global Advisors (US) | 5.338.689 | -2.697.980 | 30/6/2024 |
4,35626 % | Boxer Capital, L.L.C. | 4.960.910 | -3.255.000 | 10/10/2024 |
4,24989 % | Bellevue Asset Management AG | 4.839.779 | 0 | 30/6/2024 |
3,94101 % | Citadel Advisors LLC | 4.488.026 | 1.356.500 | 30/6/2024 |
3,58089 % | D. E. Shaw & Co., L.P. | 4.077.922 | 1.346.956 | 30/6/2024 |
3,12247 % | Deerfield Management Company, L.P. | 3.555.871 | 1.365.463 | 30/6/2024 |
2,96721 % | Johnson & Johnson Innovation-JJDC, Inc. | 3.379.064 | 0 | 30/6/2024 |
2,63240 % | Baker Bros. Advisors LP | 2.997.772 | 1.179.591 | 30/6/2024 |
2,54160 % | Morgan Stanley & Co. LLC | 2.894.375 | 71.211 | 30/6/2024 |
2,23348 % | Two Sigma Investments, LP | 2.543.487 | 840.787 | 30/6/2024 |
2,13751 % | Assenagon Asset Management S.A. | 2.434.198 | -140.505 | 30/9/2024 |
1,97347 % | Geode Capital Management, L.L.C. | 2.247.383 | 341.400 | 30/6/2024 |
1,87064 % | Dimensional Fund Advisors, L.P. | 2.130.280 | 1.067.101 | 30/6/2024 |
1,82506 % | Goldman Sachs & Company, Inc. | 2.078.374 | 464.679 | 30/6/2024 |
1,76402 % | Acadian Asset Management LLC | 2.008.862 | 294.738 | 30/6/2024 |
1,75623 % | Vestal Point Capital, LP | 2.000.000 | 1.200.000 | 30/6/2024 |
1,74371 % | BofA Global Research (US) | 1.985.732 | 65.956 | 30/6/2024 |
1,48772 % | Jacobs Levy Equity Management, Inc. | 1.694.217 | -305.605 | 30/6/2024 |
1,40442 % | BlackRock Financial Management, Inc. | 1.599.357 | 60.013 | 30/6/2024 |
1,19016 % | OrbiMed Advisors, LLC | 1.355.352 | 0 | 30/6/2024 |
0,90666 % | Invus Public Equities Advisors, LLC | 1.032.500 | 672.189 | 30/6/2024 |
0,90063 % | Federated MDTA LLC | 1.025.643 | 18.265 | 30/6/2024 |
0,87988 % | Woodline Partners LP | 1.002.002 | -890.000 | 30/6/2024 |
0,81388 % | JP Morgan Asset Management | 926.845 | -127.613 | 30/6/2024 |
0,77219 % | Charles Schwab Investment Management, Inc. | 879.375 | -76.956 | 30/6/2024 |
0,76396 % | Adage Capital Management, L.P. | 870.000 | -1.270.000 | 30/6/2024 |
0,76396 % | Soleus Capital Management, L.P. | 870.000 | 0 | 30/6/2024 |
0,74640 % | Integral Health Asset Management, LLC | 850.000 | 650.000 | 30/6/2024 |
0,61468 % | Tang Capital Management, LLC | 700.000 | 0 | 30/6/2024 |
0,59139 % | Northern Trust Investments, Inc. | 673.477 | 22.209 | 30/6/2024 |
0,54217 % | Rastetter (William H) | 617.424 | 8650 | 31/3/2024 |
0,48169 % | Renaissance Technologies LLC | 548.544 | 548.544 | 30/6/2024 |
0,45732 % | Octagon Capital Advisors LP | 520.800 | 0 | 30/6/2024 |
0,43674 % | Superstring Capital Management LP | 497.360 | -423.116 | 30/6/2024 |
0,43547 % | GCM Grosvenor Holdings, LLC | 495.916 | 0 | 30/6/2024 |
0,39223 % | Millennium Management LLC | 446.668 | 446.668 | 30/6/2024 |
0,35453 % | JPMorgan Asset Management U.K. Limited | 403.737 | -77.855 | 30/6/2024 |
0,31193 % | E Fund Management Co. Ltd. | 355.225 | 320.745 | 30/6/2024 |
0,30346 % | Perceptive Advisors LLC | 345.575 | 345.575 | 30/6/2024 |
0,28985 % | Marshall Wace LLP | 330.082 | -15.355 | 30/6/2024 |
0,28877 % | BlackRock Investment Management, LLC | 328.850 | 57.707 | 30/6/2024 |
0,28502 % | Campbell & Company, Inc. | 324.585 | 324.585 | 30/6/2024 |
0,27944 % | Nuveen LLC | 318.231 | 24.348 | 30/6/2024 |
0,27330 % | Mendlein (John D) | 311.231 | 8650 | 31/3/2024 |
0,27222 % | PGIM Quantitative Solutions LLC | 310.001 | -9100 | 30/6/2024 |
0,26344 % | Bruce & Company, Inc. | 300.000 | 157.000 | 30/6/2024 |
0,25465 % | Davis (Aaron I) | 290.000 | 290.000 | 31/1/2024 |
0,25193 % | Monaco asset management S.A.M. | 286.900 | -29.905 | 30/6/2024 |
0,24252 % | Bressi (Jerome Charles) | 276.183 | 276.183 | 14/8/2024 |
0,24232 % | Valamehr (Bahram) | 275.956 | 200.000 | 29/7/2024 |
0,24057 % | Wolchko (John Scott) | 273.965 | 27.308 | 31/3/2024 |
0,23223 % | GSA Capital Partners LLP | 264.467 | 212.188 | 30/6/2024 |
0,23043 % | Susquehanna Fundamental Investments, LLC | 262.414 | 111.293 | 30/6/2024 |
0,22853 % | Tahl (Cindy R) | 260.248 | 200.000 | 29/7/2024 |
0,22112 % | Goldman Sachs Asset Management, L.P. | 251.815 | -146.748 | 30/6/2024 |
0,22023 % | Rafferty Asset Management LLC | 250.793 | -478.864 | 30/6/2024 |
0,21288 % | Columbia Threadneedle Investments (US) | 242.432 | -41.958 | 30/6/2024 |
0,20807 % | Conestoga Capital Advisors, LLC | 236.948 | 0 | 31/3/2024 |
0,20309 % | BNY Mellon Asset Management | 231.282 | 38.222 | 30/6/2024 |
0,20121 % | BlackRock Asset Management Ireland Limited | 229.133 | -20.585 | 30/6/2024 |
0,19731 % | BlackRock Advisors (UK) Limited | 224.692 | -2124 | 30/9/2024 |
0,19120 % | Jane Street Capital, L.L.C. | 217.739 | 23.080 | 30/6/2024 |
0,19093 % | Parametric Portfolio Associates LLC | 217.427 | -6044 | 30/6/2024 |
0,18932 % | Jump Financial, LLC | 215.600 | 215.600 | 30/6/2024 |
0,15902 % | Fidelity Management & Research Company LLC | 181.089 | -74.470 | 30/6/2024 |
0,15777 % | Putnam Investment Management, L.L.C. | 179.663 | -54.452 | 30/6/2024 |
0,15727 % | Schweizerische Nationalbank | 179.100 | 179.100 | 30/6/2024 |
0,15659 % | BIT Capital GmbH | 178.324 | 178.324 | 31/12/2023 |
0,15179 % | Caxton Associates LP | 172.863 | -117.324 | 30/6/2024 |
0,14669 % | MFS Investment Management | 167.055 | 5605 | 30/6/2024 |
0,14599 % | American Century Investment Management, Inc. | 166.255 | 34.676 | 30/6/2024 |
0,14432 % | UBS Financial Services, Inc. | 164.356 | -279.694 | 30/6/2024 |
0,14050 % | Rhumbline Advisers Ltd. Partnership | 160.001 | 15.825 | 30/6/2024 |
0,12871 % | AllianceBernstein L.P. | 146.580 | 46.200 | 30/6/2024 |
0,12829 % | Pennant Investors, LP | 146.100 | 0 | 30/6/2024 |
0,12429 % | Mellon Investments Corporation | 141.540 | 33.422 | 30/6/2024 |
0,12379 % | Bellecapital AG | 140.971 | 0 | 31/3/2024 |
0,12238 % | Ohio Public Employees Retirement System | 139.366 | -8433 | 30/6/2024 |
0,11954 % | Dimensional Fund Advisors, Ltd. | 136.133 | 10.078 | 30/9/2024 |
0,11653 % | CPP Investment Board | 132.700 | 0 | 30/6/2024 |
0,11307 % | Squarepoint Capital LLP | 128.759 | 128.759 | 30/6/2024 |
0,10948 % | J.P. Morgan Private Wealth Advisors LLC | 124.679 | -23 | 30/6/2024 |
0,10732 % | Barclays Bank PLC | 122.221 | -201.355 | 30/6/2024 |
0,10187 % | Avantis Investors | 116.014 | 69.978 | 31/3/2024 |
0,09134 % | Victory Capital Management Inc. | 104.019 | -79.931 | 30/6/2024 |
0,09132 % | Abaris Investment Management AG | 104.000 | 48.000 | 31/12/2023 |
0,09047 % | Legal & General Investment Management Ltd. | 103.029 | 90.628 | 30/6/2024 |
0,08983 % | Voloridge Investment Management, LLC | 102.295 | -276.313 | 30/6/2024 |
0,08831 % | Thrivent Asset Management, LLC | 100.566 | 100.566 | 30/6/2024 |
0,08690 % | JPMorgan Private Bank (United States) | 98.963 | 394 | 30/6/2024 |
0,08293 % | UBS Fund Management (Switzerland) AG | 94.443 | 94.443 | 30/6/2024 |
0,08256 % | UBS Asset Management (Switzerland) | 94.017 | 94.017 | 30/6/2024 |
0,08135 % | BlackRock Investment Management (UK) Ltd. | 92.638 | -4991 | 30/6/2024 |
0,07873 % | California State Teachers Retirement System | 89.653 | 81.133 | 30/6/2024 |
0,07773 % | HSBC Global Asset Management (UK) Limited | 88.514 | 22.583 | 30/6/2024 |
0,06858 % | UBS Asset Management (UK) Ltd. | 78.100 | 0 | 31/8/2024 |