10,25121 % | The Vanguard Group, Inc. | 7.043.603 | 381.738 | 30/8/2024 |
9,78968 % | EcoR1 Capital, LLC | 6.726.491 | 0 | 30/6/2024 |
7,39670 % | BlackRock Institutional Trust Company, N.A. | 5.082.270 | 684.350 | 30/6/2024 |
5,62522 % | T. Rowe Price Associates, Inc. | 3.865.089 | -397.469 | 30/6/2024 |
5,03248 % | Pfizer Inc | 3.457.815 | 3.457.815 | 31/3/2024 |
4,34849 % | Avidity Partners Management LP | 2.987.845 | 2655 | 30/6/2024 |
4,31945 % | RTW Investments L.P. | 2.967.897 | -330.000 | 30/6/2024 |
3,84151 % | Citadel Advisors LLC | 2.639.499 | 358.886 | 30/6/2024 |
3,54846 % | Paradigm BioCapital Advisors LP | 2.438.149 | -176.786 | 30/6/2024 |
3,47955 % | Bellevue Asset Management AG | 2.390.800 | 0 | 30/6/2024 |
2,74248 % | Commodore Capital LP | 1.884.361 | 609.361 | 30/6/2024 |
2,47371 % | State Street Global Advisors (US) | 1.699.688 | 317.521 | 30/6/2024 |
2,24383 % | Geode Capital Management, L.L.C. | 1.541.737 | 228.421 | 30/6/2024 |
2,21219 % | Fidelity Management & Research Company LLC | 1.519.994 | 327.235 | 30/6/2024 |
2,04977 % | Nextech Invest, Ltd. | 1.408.394 | 0 | 30/6/2024 |
1,87676 % | New Leaf Venture Partners LLC | 1.289.521 | 0 | 30/6/2024 |
1,85471 % | JP Morgan Asset Management | 1.274.370 | 285.234 | 30/6/2024 |
1,78537 % | ArrowMark Colorado Holdings, LLC | 1.226.727 | 21.159 | 30/6/2024 |
1,68723 % | Fidelity Institutional Asset Management | 1.159.293 | -36.902 | 30/6/2024 |
1,56927 % | Norges Bank Investment Management (NBIM) | 1.078.246 | 200.538 | 30/6/2024 |
1,49578 % | Perceptive Advisors LLC | 1.027.749 | -208.854 | 30/6/2024 |
1,26001 % | Houston (John G) | 865.750 | -188.441 | 31/3/2024 |
0,94166 % | BlackRock Financial Management, Inc. | 647.013 | 12.037 | 30/6/2024 |
0,91368 % | VR Adviser, LLC | 627.788 | 0 | 30/6/2024 |
0,91124 % | JPMorgan Asset Management U.K. Limited | 626.116 | -27.572 | 30/6/2024 |
0,88846 % | Candriam Belgium S.A. | 610.458 | 147.904 | 30/6/2024 |
0,88577 % | Boxer Capital, L.L.C. | 608.614 | 0 | 30/6/2024 |
0,84690 % | Morgan Stanley & Co. LLC | 581.908 | 23.097 | 30/6/2024 |
0,83595 % | Finepoint Capital LP | 574.378 | 35.278 | 30/6/2024 |
0,80774 % | Opaleye Management Inc. | 555.000 | 225.000 | 30/6/2024 |
0,79247 % | Charles Schwab Investment Management, Inc. | 544.503 | 16.448 | 30/6/2024 |
0,78039 % | Candriam Luxembourg S.A. | 536.205 | 0 | 30/9/2024 |
0,75277 % | Braidwell LP | 517.230 | 517.230 | 30/6/2024 |
0,74728 % | Goldman Sachs & Company, Inc. | 513.457 | 19.407 | 30/6/2024 |
0,67521 % | Dimensional Fund Advisors, L.P. | 463.935 | 29.635 | 30/6/2024 |
0,65558 % | Northern Trust Investments, Inc. | 450.451 | -11.992 | 30/6/2024 |
0,62402 % | Aquilo Capital Management, LLC | 428.766 | 23.000 | 30/6/2024 |
0,61581 % | Woodline Partners LP | 423.124 | 920 | 30/6/2024 |
0,61323 % | RA Capital Management, LP | 421.348 | 0 | 30/6/2024 |
0,47386 % | American Century Investment Management, Inc. | 325.590 | 72 | 30/6/2024 |
0,46010 % | Brown Advisory | 316.138 | 41.963 | 30/6/2024 |
0,43625 % | Qube Research & Technologies Ltd | 299.745 | 185.344 | 30/6/2024 |
0,41527 % | Frazier Life Sciences Management, L.P. | 285.331 | 0 | 30/6/2024 |
0,41493 % | Gilder Gagnon Howe & Co. LLC | 285.099 | -39.745 | 30/6/2024 |
0,40086 % | Wasatch Global Investors Inc | 275.433 | 68.007 | 30/6/2024 |
0,40082 % | Renaissance Technologies LLC | 275.400 | -86.573 | 30/6/2024 |
0,37354 % | PanAgora Asset Management Inc. | 256.658 | 93.568 | 30/6/2024 |
0,37310 % | UBS Financial Services, Inc. | 256.359 | -37.685 | 30/6/2024 |
0,34598 % | Schonfeld Strategic Advisors LLC | 237.724 | -43.373 | 30/6/2024 |
0,34373 % | Nordea Funds Oy | 236.174 | -40.308 | 30/6/2024 |
0,33474 % | Rhenman & Partners Asset Management AB | 230.000 | 60.000 | 30/6/2024 |
0,32652 % | D. E. Shaw & Co., L.P. | 224.351 | -79.287 | 30/6/2024 |
0,32022 % | Two Sigma Investments, LP | 220.026 | 66.707 | 30/6/2024 |
0,31301 % | BlackRock Advisors (UK) Limited | 215.070 | 348 | 30/9/2024 |
0,31116 % | UBS Asset Management (UK) Ltd. | 213.798 | 182.472 | 30/6/2024 |
0,30906 % | Kennedy Capital Management LLC | 212.354 | 144.651 | 30/6/2024 |
0,29137 % | Millennium Management LLC | 200.199 | -43.468 | 30/6/2024 |
0,28923 % | BlackRock Asset Management Ireland Limited | 198.731 | 1794 | 30/6/2024 |
0,28855 % | Nuveen LLC | 198.262 | -94.577 | 30/6/2024 |
0,27804 % | Amundi Asset Management US, Inc. | 191.044 | -2297 | 30/6/2024 |
0,26197 % | Tang Capital Management, LLC | 180.000 | 0 | 30/6/2024 |
0,25666 % | Federated MDTA LLC | 176.352 | 4389 | 30/6/2024 |
0,25114 % | BlackRock Investment Management, LLC | 172.561 | 43.501 | 30/6/2024 |
0,24407 % | Voloridge Investment Management, LLC | 167.703 | -211.673 | 30/6/2024 |
0,24388 % | Cassidy (Sean A) | 167.572 | -19.135 | 31/3/2024 |
0,23260 % | BNY Mellon Asset Management | 159.819 | 36.321 | 30/6/2024 |
0,22333 % | Hudson Bay Capital Management LP | 153.448 | 153.448 | 30/6/2024 |
0,22012 % | Neuberger Berman, LLC | 151.245 | 94.875 | 30/6/2024 |
0,20721 % | BofA Global Research (US) | 142.375 | -12.111 | 30/6/2024 |
0,20338 % | Assenagon Asset Management S.A. | 139.741 | 111.795 | 30/9/2024 |
0,18811 % | Jane Street Capital, L.L.C. | 129.248 | 19.570 | 30/6/2024 |
0,18216 % | Parkman Healthcare Partners LLC | 125.161 | 182 | 30/6/2024 |
0,18015 % | T. Rowe Price International Ltd | 123.780 | 17.920 | 30/6/2024 |
0,17585 % | Banque Pictet & Cie S.A. | 120.824 | 38.455 | 30/9/2024 |
0,17354 % | UBS Asset Management (Americas), Inc. | 119.236 | -887 | 30/6/2024 |
0,17304 % | Squarepoint Capital LLP | 118.899 | 37.028 | 30/6/2024 |
0,15783 % | Schroder Investment Management Ltd. (SIM) | 108.444 | 91.444 | 30/6/2024 |
0,15303 % | Nordea Investment Management AB (Denmark) | 105.146 | -6082 | 31/8/2024 |
0,14861 % | Parametric Portfolio Associates LLC | 102.107 | -5419 | 30/6/2024 |
0,14554 % | Wanjia Asset Management Co., Ltd. | 100.000 | -50.000 | 30/6/2024 |
0,14554 % | Saint Olive Gestion | 100.000 | 0 | 31/7/2024 |
0,14380 % | BlackRock Investment Management (UK) Ltd. | 98.803 | 27.094 | 30/6/2024 |
0,13842 % | Manulife Investment Management (North America) Limited | 95.105 | -24.376 | 30/6/2024 |
0,13776 % | Columbia Threadneedle Investments (US) | 94.658 | 20.265 | 30/6/2024 |
0,13681 % | Schweizerische Nationalbank | 94.000 | -20.100 | 30/6/2024 |
0,13670 % | Taylor (Ian) | 93.928 | -56.279 | 31/3/2024 |
0,13498 % | Morgan Stanley Investment Management Inc. (US) | 92.745 | 87.661 | 30/6/2024 |
0,13324 % | TD Asset Management Inc. | 91.548 | -107.800 | 30/6/2024 |
0,13295 % | Verition Fund Management LLC | 91.351 | 15.800 | 30/6/2024 |
0,13132 % | Rhumbline Advisers Ltd. Partnership | 90.229 | 19.024 | 30/6/2024 |
0,12343 % | DWS Investments UK Limited | 84.812 | -12.760 | 30/6/2024 |
0,12326 % | BNP Paribas Securities Corp. North America | 84.692 | -62.563 | 30/6/2024 |
0,11992 % | Exome Asset Management LLC | 82.400 | 82.400 | 30/6/2024 |
0,11905 % | Zacks Investment Management, Inc. | 81.798 | 5977 | 30/6/2024 |
0,11784 % | Goldman Sachs Asset Management, L.P. | 80.968 | -11.960 | 30/6/2024 |
0,11437 % | abrdn Inc. | 78.585 | 17.093 | 30/9/2024 |
0,10915 % | Ghost Tree Capital, LLC | 75.000 | 35.000 | 30/6/2024 |
0,10729 % | AllianceBernstein L.P. | 73.720 | 17.250 | 30/6/2024 |
0,10680 % | Citi Investment Research (US) | 73.382 | 56.213 | 30/6/2024 |
0,10262 % | Mellon Investments Corporation | 70.513 | 21.679 | 30/6/2024 |