13,00464 % | CPMG, Inc. | 6.183.603 | 2.219.962 | 31/12/2022 |
9,98999 % | Nantahala Capital Management, LLC | 4.750.161 | 693.534 | 4/1/2023 |
7,83732 % | Stonepine Capital Management, LLC | 3.726.584 | 0 | 4/1/2023 |
5,01913 % | Citi Investment Research (US) | 2.386.557 | 376.119 | 31/12/2022 |
3,68040 % | Deerfield Management Company, L.P. | 1.750.000 | 0 | 31/12/2022 |
3,46051 % | Archon Capital Management LLC | 1.645.443 | -196.641 | 31/12/2022 |
3,11922 % | Lytton (Laurence W) | 1.483.162 | 1.183.979 | 4/1/2023 |
3,08600 % | The Vanguard Group, Inc. | 1.467.367 | 105.589 | 31/12/2022 |
2,25945 % | J.P. Morgan Securities LLC | 1.074.350 | 1.074.350 | 31/12/2022 |
1,65473 % | AWM Investment Company, Inc. | 786.809 | -43.288 | 31/12/2022 |
1,60423 % | Woodline Partners LP | 762.800 | 762.800 | 31/12/2022 |
1,51090 % | Boone Capital Management LLC | 718.419 | 718.419 | 31/12/2022 |
1,50894 % | Gagnon Securities LLC | 717.490 | -985.685 | 2/2/2023 |
1,31443 % | Berry Street Capital Management LLP | 625.000 | 625.000 | 31/12/2022 |
1,10859 % | Parian Global Management LP | 527.126 | -205.840 | 30/9/2022 |
1,07916 % | Gabelli Funds, LLC | 513.131 | 510.631 | 31/12/2022 |
1,06318 % | BlackRock Institutional Trust Company, N.A. | 505.532 | -57.854 | 31/12/2022 |
0,99826 % | Vivaldi Asset Management, LLC | 474.664 | 474.664 | 31/12/2022 |
0,94562 % | Water Island Capital, LLC | 449.636 | 90.636 | 31/12/2022 |
0,92517 % | Millennium Management LLC | 439.913 | 388.982 | 31/12/2022 |
0,87319 % | Magnetar Capital Partners LP | 415.194 | 415.194 | 31/12/2022 |
0,78446 % | Gilder Gagnon Howe & Co. LLC | 373.005 | -88.582 | 31/12/2022 |
0,78304 % | Geode Capital Management, L.L.C. | 372.329 | 28.878 | 31/12/2022 |
0,71337 % | Morgan Stanley & Co. LLC | 339.200 | 339.200 | 31/12/2022 |
0,69768 % | IndexIQ Advisors LLC | 331.741 | 331.741 | 28/2/2023 |
0,64775 % | Federated Hermes Global Investment Management Corp. | 308.000 | 308.000 | 31/12/2022 |
0,60157 % | Qube Research & Technologies Ltd | 286.040 | 286.040 | 31/12/2022 |
0,55989 % | Newton (K Todd) | 266.223 | 125.817 | 4/1/2023 |
0,54115 % | Bardin Hill Investment Partners LP | 257.312 | 257.312 | 31/12/2022 |
0,50209 % | AIGH Capital Management, LLC. | 238.740 | -143.261 | 31/12/2022 |
0,46976 % | McKhann (Charles S.) | 223.365 | 63.943 | 4/1/2023 |
0,44081 % | Renaissance Technologies LLC | 209.600 | 114.300 | 31/12/2022 |
0,41360 % | TIG Advisors, L.L.C. | 196.665 | 196.665 | 31/12/2022 |
0,36846 % | Bridgeway Capital Management, LLC | 175.200 | 0 | 31/12/2022 |
0,35752 % | Apis Capital Advisors LLC | 170.000 | 30.000 | 31/12/2022 |
0,34846 % | GWM Asset Management, Ltd. | 165.691 | 165.691 | 31/12/2022 |
0,34269 % | Glazer Capital, LLC | 162.947 | 162.947 | 31/12/2022 |
0,34180 % | Susquehanna International Group, LLP | 162.525 | 162.525 | 31/12/2022 |
0,33957 % | Russell Investments Trust Company | 161.463 | -77.370 | 31/12/2022 |
0,32335 % | Cigogne Management S.A. | 153.750 | 153.750 | 31/12/2022 |
0,31231 % | Northern Trust Investments, Inc. | 148.499 | 3585 | 31/12/2022 |
0,29233 % | BCK Capital Management LP | 139.000 | 139.000 | 31/12/2022 |
0,28670 % | Boston Partners | 136.323 | -32.210 | 31/12/2022 |
0,27340 % | New Jersey Division of Investment | 130.000 | 0 | 31/12/2022 |
0,24809 % | State Street Global Advisors (US) | 117.966 | 28.600 | 31/12/2022 |
0,23902 % | Cavanaugh (Stefanie L CPA) | 113.653 | 70.993 | 4/1/2023 |
0,23049 % | Anderson (Rick D) | 109.596 | 14.224 | 14/6/2022 |
0,21820 % | Black (Jeffrey G) | 103.750 | -38.900 | 4/1/2023 |
0,16950 % | HRT Financial LP | 80.598 | 80.598 | 31/12/2022 |
0,16720 % | Goldman Sachs & Company, Inc. | 79.502 | -746.980 | 31/12/2022 |
0,16340 % | Worth Venture Partners, LLC | 77.696 | -48.839 | 31/12/2022 |
0,14665 % | Goldman Sachs Bank AG | 69.731 | 0 | 31/12/2022 |
0,12881 % | Dimensional Fund Advisors, L.P. | 61.247 | -5142 | 31/12/2022 |
0,10597 % | Molesphini (John J) | 50.386 | 23.106 | 4/1/2023 |
0,10561 % | CSS, LLC | 50.215 | 50.215 | 31/12/2022 |
0,10515 % | Neuberger Berman, LLC | 50.000 | 0 | 31/12/2022 |
0,10515 % | Harvest Management, LLC | 50.000 | 50.000 | 31/12/2022 |
0,10299 % | Trexquant Investment LP | 48.973 | 48.973 | 31/12/2022 |
0,10114 % | Northern Trust Global Investments | 48.090 | 0 | 31/12/2022 |
0,09201 % | Maven Investment Partners US Ltd. | 43.751 | 43.751 | 31/12/2022 |
0,08740 % | Jane Street Capital, L.L.C. | 41.559 | 41.559 | 31/12/2022 |
0,08615 % | BofA Global Research (US) | 40.965 | 1758 | 31/12/2022 |
0,08187 % | Newton Investment Management North America, LLC | 38.930 | 0 | 31/12/2022 |
0,07849 % | Crystalline Management, Inc. | 37.319 | 37.319 | 31/12/2022 |
0,07488 % | O'Keefe (Sharon L) | 35.604 | 35.604 | 5/8/2022 |
0,07483 % | Jump Financial, LLC | 35.582 | 24.382 | 31/12/2022 |
0,07430 % | UBS Financial Services, Inc. | 35.328 | 31.773 | 31/12/2022 |
0,06833 % | Trium Capital LLP | 32.488 | 32.488 | 31/12/2022 |
0,06562 % | University of Texas Investment Management Company | 31.202 | 0 | 31/12/2022 |
0,06279 % | Barr (John R) | 29.858 | -10.336 | 4/1/2023 |
0,05684 % | McClellan (William D Jr) | 27.025 | -10.336 | 4/1/2023 |
0,05678 % | Thompson, Davis & Co., Inc. (Asset Management) | 27.000 | -47.078 | 31/12/2022 |
0,05664 % | Schonfeld Strategic Advisors LLC | 26.931 | 26.931 | 31/12/2022 |
0,05074 % | Quantbot Technologies, LP | 24.125 | 24.125 | 31/12/2022 |
0,04584 % | Shimer (Julie Ann) | 21.797 | -10.336 | 4/1/2023 |
0,04127 % | Cubist Systematic Strategies, LLC | 19.623 | 19.623 | 31/12/2022 |
0,03735 % | Barclays Capital Inc. | 17.762 | 16.604 | 31/12/2022 |
0,03710 % | Bankes (Jeannette) | 17.641 | 14.224 | 14/6/2022 |
0,03617 % | Charles Schwab Investment Management, Inc. | 17.198 | 0 | 31/12/2022 |
0,03578 % | BNY Mellon Asset Management | 17.011 | 7594 | 31/12/2022 |
0,03379 % | Lighthouse Partners | 16.065 | 16.065 | 31/12/2022 |
0,02923 % | Highland Capital Management Fund Advisors, L.P. | 13.900 | 13.900 | 31/12/2022 |
0,02734 % | Verition Fund Management LLC | 13.000 | 13.000 | 31/12/2022 |
0,02672 % | Balyasny Asset Management LP | 12.706 | 12.706 | 31/12/2022 |
0,02662 % | Squarepoint Capital LLP | 12.658 | 12.658 | 31/12/2022 |
0,02549 % | Mirabella Financial Services LLP | 12.120 | 12.120 | 31/12/2022 |
0,02345 % | Morris Financial Concepts, INC | 11.149 | 11.149 | 31/12/2022 |
0,02191 % | Citadel Advisors LLC | 10.417 | -55.610 | 31/12/2022 |
0,01414 % | Wolverine Asset Management, LLC | 6724 | 6724 | 31/12/2022 |
0,01301 % | BlackRock Investment Management, LLC | 6186 | 554 | 31/12/2022 |
0,01301 % | Lord, Abbett & Co. LLC | 6186 | 0 | 31/1/2023 |
0,01199 % | Lazard Asset Management, L.L.C. | 5701 | -5203 | 31/12/2022 |
0,00818 % | Pacitti (David) | 3888 | -10.336 | 4/1/2023 |
0,00735 % | Tower Research Capital LLC | 3495 | 3231 | 31/12/2022 |
0,00486 % | Invesco Capital Management LLC | 2312 | 0 | 31/1/2023 |
0,00411 % | Morgan Stanley Smith Barney LLC | 1952 | 0 | 31/12/2022 |
0,00314 % | Morgan Stanley & Co. International Plc | 1495 | 1495 | 31/12/2022 |
0,00273 % | Cutler Group, LP | 1300 | 1300 | 31/12/2022 |
0,00215 % | BlackRock Financial Management, Inc. | 1023 | -2271 | 31/12/2022 |
0,00212 % | Russell Investments Limited | 1006 | -937 | 31/12/2022 |