6,04 % | BlackRock Institutional Trust Company, N.A. | 8.995.574 | 593.702 | 31/12/2023 |
4,76 % | The Vanguard Group, Inc. | 7.086.345 | 60.181 | 31/12/2023 |
3,98 % | Stonepine Capital Management, LLC | 5.937.000 | 21.628 | 31/12/2023 |
3,79 % | Caxton Associates LP | 5.641.920 | 0 | 31/12/2023 |
2,58 % | BioImpact Capital LLC | 3.847.232 | -140.735 | 31/12/2023 |
2,38 % | Rosalind Advisors, Inc. | 3.543.685 | 3.543.685 | 31/12/2023 |
1,94 % | Geode Capital Management, L.L.C. | 2.892.077 | 118.784 | 31/12/2023 |
1,83 % | State Street Global Advisors (US) | 2.724.126 | 154.004 | 31/12/2023 |
1,68 % | Medical Strategy GmbH | 2.505.175 | -220.231 | 31/12/2023 |
1,59 % | Edick (Paul Raymond) | 2.373.211 | 1.500.000 | 31/1/2024 |
1,08 % | Pieper (Steven) | 1.611.858 | 450.000 | 31/1/2024 |
1,04 % | Millennium Management LLC | 1.547.955 | -726.189 | 31/12/2023 |
0,93 % | Renaissance Technologies LLC | 1.381.640 | 359.600 | 31/12/2023 |
0,79 % | Morgan Stanley & Co. LLC | 1.184.474 | 588.213 | 31/12/2023 |
0,73 % | Shannon John Patrick Jr | 1.094.092 | 750.000 | 31/1/2024 |
0,72 % | Northern Trust Investments, Inc. | 1.077.211 | 41.744 | 31/12/2023 |
0,71 % | D. E. Shaw & Co., L.P. | 1.054.610 | 179.200 | 31/12/2023 |
0,70 % | Redmile Group, LLC | 1.046.587 | 0 | 31/12/2023 |
0,61 % | Hecht (Beth P) | 916.324 | 750.000 | 31/1/2024 |
0,55 % | Johnson John H | 825.983 | 305.171 | 18/3/2024 |
0,49 % | Prestrelski (Steven) | 729.524 | 150.000 | 31/1/2023 |
0,39 % | BlackRock Financial Management, Inc. | 579.257 | 31.275 | 31/12/2023 |
0,38 % | Invenomic Capital Management LP | 568.619 | 568.619 | 31/12/2023 |
0,37 % | Tudor Investment Corporation | 553.411 | -88.087 | 31/12/2023 |
0,35 % | Columbia Threadneedle Investments (US) | 520.121 | -67.817 | 31/12/2023 |
0,30 % | Johnson (Kenneth Erland) | 441.890 | 175.000 | 31/1/2024 |
0,28 % | Nuveen LLC | 419.567 | -293.130 | 31/12/2023 |
0,28 % | GSA Capital Partners LLP | 416.267 | 35.036 | 31/12/2023 |
0,27 % | Lazard Asset Management, L.L.C. | 403.813 | 88.326 | 31/12/2023 |
0,27 % | Citadel Advisors LLC | 400.577 | 371.383 | 31/12/2023 |
0,26 % | Knott Partners Management, LLC | 387.910 | 387.910 | 31/12/2023 |
0,24 % | Charles Schwab Investment Management, Inc. | 364.382 | -631 | 31/12/2023 |
0,23 % | BlackRock Investment Management, LLC | 347.708 | -3 | 31/12/2023 |
0,22 % | BNY Mellon Asset Management | 331.188 | -42.501 | 31/12/2023 |
0,19 % | IHT Wealth Management, LLC | 279.392 | -5.000 | 31/12/2023 |
0,19 % | Barclays Bank PLC | 275.963 | 170.220 | 31/12/2023 |
0,18 % | AQR Capital Management, LLC | 273.222 | 230.942 | 31/12/2023 |
0,18 % | Alpine Global Management, LLC | 270.000 | -30.000 | 31/12/2023 |
0,17 % | BofA Global Research (US) | 260.379 | 190.592 | 31/12/2023 |
0,15 % | Jane Street Capital, L.L.C. | 223.584 | 79.980 | 31/12/2023 |
0,14 % | Brown Advisory | 211.405 | -18.100 | 31/12/2023 |
0,14 % | J.P. Morgan Securities LLC | 207.442 | 207.442 | 31/12/2023 |
0,13 % | Commonwealth Financial Network | 187.003 | 40.769 | 31/12/2023 |
0,12 % | Goldman Sachs & Company, Inc. | 180.585 | 102.571 | 31/12/2023 |
0,12 % | Diversified Trust Company | 175.741 | 20.091 | 31/3/2024 |
0,11 % | Rhumbline Advisers Ltd. Partnership | 171.292 | -2.516 | 31/12/2023 |
0,11 % | Susquehanna International Group, LLP | 163.229 | 56.998 | 31/12/2023 |
0,10 % | Hamblin Watsa Investment Counsel Ltd. | 151.395 | 0 | 31/12/2023 |
0,10 % | Tang Capital Management, LLC | 150.000 | 0 | 31/12/2023 |
0,09 % | PanAgora Asset Management Inc. | 140.318 | -109.882 | 31/12/2023 |
0,09 % | UBS Financial Services, Inc. | 134.412 | 59.972 | 31/12/2023 |
0,09 % | Mariner Wealth Advisors | 129.390 | -62.354 | 31/12/2023 |
0,08 % | Cetera Advisor Networks LLC | 116.990 | 4.704 | 31/12/2023 |
0,08 % | T. Rowe Price International Ltd | 115.003 | 2.180 | 31/12/2023 |
0,08 % | Two Sigma Investments, LP | 114.213 | 4.287 | 31/12/2023 |
0,07 % | CenterBook Partners LP | 110.627 | 110.627 | 31/12/2023 |
0,07 % | Sherman (Jeffrey W) | 99.380 | 6.502 | 15/3/2024 |
0,07 % | Kong (Garheng) | 99.144 | 6.474 | 15/3/2024 |
0,06 % | Assenagon Asset Management S.A. | 95.144 | 6.877 | 29/2/2024 |
0,06 % | Northern Trust Global Investments | 88.152 | -21.598 | 31/12/2023 |
0,06 % | JPMorgan Private Bank (United States) | 88.016 | 88.016 | 31/12/2023 |
0,06 % | State Street Global Advisors Ireland Limited | 87.770 | -319 | 30/4/2023 |
0,06 % | HRT Financial LP | 87.334 | 87.334 | 31/12/2023 |
0,06 % | Fairley (Ricki Louise) | 85.000 | 85.000 | 27/3/2023 |
0,05 % | BlackRock Advisors (UK) Limited | 80.582 | 3.885 | 31/3/2024 |
0,05 % | AllianceBernstein L.P. | 80.420 | 0 | 31/12/2023 |
0,05 % | Group One Trading, L.P. | 78.951 | 12.781 | 31/12/2023 |
0,05 % | Goldman Sachs Asset Management, L.P. | 78.104 | 23.278 | 31/12/2023 |
0,05 % | BlackRock Asset Management Ireland Limited | 74.649 | 18.323 | 31/12/2023 |
0,05 % | MetLife Investment Management, LLC | 71.237 | 0 | 31/12/2023 |
0,04 % | SunAmerica Asset Management, LLC | 66.140 | -267 | 31/12/2023 |
0,04 % | State Teachers Retirement System of Ohio | 64.300 | 0 | 31/12/2023 |
0,04 % | Soleus Capital Management, L.P. | 62.083 | -242.000 | 31/12/2023 |
0,04 % | GPS Wealth Strategies Group, LLC | 62.025 | -2.000 | 31/12/2023 |
0,04 % | DWS Investments UK Limited | 61.635 | -2.002 | 31/12/2023 |
0,04 % | Invesco Advisers, Inc. | 58.050 | -252.932 | 31/12/2023 |
0,04 % | LJI Wealth Management, LLC | 56.050 | -5.300 | 31/12/2023 |
0,04 % | Voya Investment Management LLC | 55.877 | 2.031 | 31/12/2023 |
0,04 % | Annandale Capital, LLC | 55.820 | 30.820 | 31/12/2023 |
0,04 % | Manulife Investment Management (North America) Limited | 55.742 | 0 | 31/12/2023 |
0,03 % | Deltec Asset Management, LLC | 52.000 | -207.246 | 31/3/2024 |
0,03 % | Chevy Chase Trust Company | 51.243 | 0 | 31/12/2023 |
0,03 % | IEQ Capital LLC | 50.169 | 0 | 31/12/2023 |
0,03 % | Schmid (John P) | 48.159 | 42.500 | 7/6/2023 |
0,03 % | Principal Global Investors (Equity) | 44.725 | 1.601 | 31/12/2023 |
0,03 % | Halkuff (Dawn) | 42.500 | 42.500 | 7/6/2023 |
0,03 % | Persky (Marla S) | 42.500 | 42.500 | 7/6/2023 |
0,03 % | Bormann-Kennedy (Barbara-Jean Anne) | 42.500 | 42.500 | 7/6/2023 |
0,03 % | Centiva Capital, LP | 42.368 | 42.368 | 31/12/2023 |
0,03 % | Mellon Investments Corporation | 39.254 | 0 | 31/12/2023 |
0,03 % | Florida State Board of Administration | 37.970 | 0 | 31/12/2023 |
0,02 % | Graham Capital Management, L.P. | 36.784 | -20.625 | 31/12/2023 |
0,02 % | Walleye Capital LLC | 35.927 | -88.763 | 31/12/2023 |
0,02 % | Wells Fargo Bank, N.A. | 34.513 | 7.853 | 31/12/2023 |
0,02 % | SG Americas Securities, L.L.C. | 33.777 | 15.414 | 31/12/2023 |
0,02 % | LPL Financial LLC | 33.375 | 33.375 | 31/12/2023 |
0,02 % | Cambridge Investment Research Advisors, Inc. | 32.170 | -3.500 | 31/12/2023 |
0,02 % | PGIM Quantitative Solutions LLC | 31.475 | 0 | 31/12/2023 |
0,02 % | ProShare Advisors LLC | 30.849 | 4.537 | 31/12/2023 |
0,02 % | RBC Wealth Management, International | 28.385 | 11.724 | 31/12/2023 |