18.71362 % | Casdin Capital, LLC | 69,455,605 | 46,716,861 | |
15.80255 % | Viking Global Investors LP | 58,651,170 | 46,465,096 | |
4.05148 % | Millennium Management LLC | 15,037,065 | 13,559,148 | |
3.51406 % | ARK Investment Management LLC | 13,042,440 | -7,987,960 | |
2.38542 % | Nikko Asset Management Co., Ltd. | 8,853,491 | 8,853,491 | |
2.00626 % | Indaba Capital Management, L.P. | 7,446,229 | 0 | |
1.89746 % | Caligan Partners, LP | 7,042,413 | 0 | |
1.18081 % | Neuberger Berman, LLC | 4,382,584 | 16,771 | |
1.11382 % | The Vanguard Group, Inc. | 4,133,939 | 159,413 | |
1.02315 % | Morgan Stanley Investment Management Inc. (US) | 3,797,425 | -621,642 | |
0.82283 % | PRIMECAP Management Company | 3,053,943 | -29,137 | |
0.64567 % | North Sound Management, LLC | 2,396,400 | -1,978,600 | |
0.58795 % | Balyasny Asset Management LP | 2,182,187 | -514,523 | |
0.50503 % | Hollow Brook Wealth Management, LLC | 1,874,405 | 88,648 | |
0.36840 % | BlackRock Institutional Trust Company, N.A. | 1,367,305 | 28,260 | |
0.30296 % | Needham Investment Management L.L.C. | 1,124,435 | -100,000 | |
0.28010 % | Renaissance Technologies LLC | 1,039,600 | 426,200 | |
0.26407 % | MFP Investors, LLC | 980,100 | 0 | |
0.21766 % | Boothbay Fund Management, LLC | 807,858 | -398,156 | |
0.21717 % | Geode Capital Management, L.L.C. | 806,042 | 48,228 | |
0.16264 % | Parkman Healthcare Partners LLC | 603,620 | 103,620 | |
0.14053 % | Egholm Michael | 521,592 | 306,074 | |
0.12127 % | Azimut Capital Management Sgr SpA | 450,103 | 0 | |
0.08726 % | Neuberger Berman Asset Management Ireland Ltd | 323,853 | 13,657 | |
0.08718 % | Citi Investment Research (US) | 323,572 | 133,781 | |
0.08513 % | Jane Street Capital, L.L.C. | 315,949 | 280,316 | |
0.08487 % | Nahum (Benjamin H) | 315,000 | 315,000 | |
0.08411 % | ARIAD Asset Management GmbH | 312,180 | 0 | |
0.08083 % | Laurion Capital Management LP | 300,010 | 300,010 | |
0.08046 % | State Street Global Advisors (US) | 298,637 | 19,100 | |
0.07791 % | Sempione SIM SpA | 289,173 | 0 | |
0.07266 % | Jog (Vikram) | 269,683 | 45,718 | |
0.06678 % | Two Sigma Investments, LP | 247,845 | 227,945 | |
0.06244 % | Linthwaite (Stephen Christopher) | 231,738 | -96,735 | |
0.05712 % | Bridgeway Capital Management, LLC | 212,000 | 0 | |
0.05687 % | Kim Hanjoon Alex | 211,068 | 140,885 | |
0.05653 % | Dimensional Fund Advisors, Ltd. | 209,815 | 209,815 | |
0.05340 % | AHL Partners LLP | 198,180 | 198,180 | |
0.05338 % | Cox (Troy M) | 198,104 | 198,104 | |
0.05276 % | Davis (Jeremy Steven) | 195,833 | 178,176 | |
0.05191 % | Hightower Advisors, LLC | 192,670 | 0 | |
0.05154 % | Schonfeld Strategic Advisors LLC | 191,284 | 48,284 | |
0.04951 % | Northern Trust Investments, Inc. | 183,761 | -1,145 | |
0.04776 % | Susquehanna International Group, LLP | 177,246 | 81,015 | |
0.04063 % | HBK Investments, L.P. | 150,781 | 150,781 | |
0.03727 % | J.P. Morgan Securities LLC | 138,342 | 137,242 | |
0.03599 % | Goldman Sachs & Company, Inc. | 133,560 | 133,560 | |
0.03520 % | Rockefeller Capital Management | 130,643 | -1,125 | |
0.03368 % | Silverback Asset Management, LLC | 125,000 | -175,000 | |
0.03290 % | Lauxera Capital Partners | 122,100 | 122,100 | |
0.03087 % | BlackRock (Netherlands) B.V. | 114,561 | 114,561 | |
0.02967 % | BNY Mellon Asset Management | 110,121 | 12,420 | |
0.02838 % | Credit Suisse Funds AG | 105,318 | 0 | |
0.02808 % | Morgan Stanley & Co. LLC | 104,207 | 96,609 | |
0.02790 % | Casdin (Eli) | 103,556 | 0 | |
0.02707 % | Paya (Carlos V) | 100,468 | -26,376 | |
0.02471 % | Barclays Capital Inc. | 91,698 | 91,698 | |
0.02349 % | 683 Capital Management LLC | 87,189 | 87,189 | |
0.02317 % | Black (Jeffrey G) | 85,984 | 85,984 | |
0.02197 % | BofA Global Research (US) | 81,558 | 71,128 | |
0.02140 % | Hibbs (Kathy L) | 79,412 | 79,412 | |
0.02140 % | Carey Thomas D | 79,412 | 79,412 | |
0.02107 % | Clague (Laura M) | 78,215 | -26,576 | |
0.02000 % | Schoolcraft Capital LLC | 74,224 | 74,224 | |
0.01941 % | ExodusPoint Capital Management, LP | 72,025 | 72,025 | |
0.01932 % | Barclays Bank PLC | 71,694 | 23,500 | |
0.01922 % | Citadel Advisors LLC | 71,319 | -42,206 | |
0.01899 % | Jump Financial, LLC | 70,480 | 38,030 | |
0.01883 % | Manulife Investment Management (North America) Limited | 69,893 | 68,269 | |
0.01780 % | Madaus (Martin D Ph.D.) | 66,048 | 4,863 | |
0.01765 % | Assenagon Asset Management S.A. | 65,502 | 65,502 | |
0.01691 % | Intellectus Partners, LLC | 62,768 | 0 | |
0.01628 % | BlackRock Advisors (UK) Limited | 60,439 | 60,439 | |
0.01525 % | Polar Capital LLP | 56,585 | -43,415 | |
0.01520 % | Jefferies LLC | 56,400 | 0 | |
0.01503 % | KLP Fondsforvaltning AS | 55,766 | -1 | |
0.01480 % | Vanguard Investments Australia Ltd. | 54,927 | -11 | |
0.01353 % | RBC Dominion Securities, Inc. | 50,235 | 0 | |
0.01347 % | Paradigm Capital Management, Inc. | 50,000 | 50,000 | |
0.01347 % | Gesing (Rand W.) | 50,000 | 50,000 | |
0.01347 % | Bradley & Co. Private Wealth Management, LLC | 50,000 | 0 | |
0.01156 % | Commonwealth Financial Network | 42,914 | 12,832 | |
0.01064 % | Y-Intercept (Hong Kong) Ltd | 39,508 | 39,508 | |
0.00980 % | Squarepoint Capital LLP | 36,381 | 36,381 | |
0.00938 % | Legal & General Investment Management Ltd. | 34,828 | 0 | |
0.00938 % | Witney (Franklin R. Ph.D.) | 34,809 | -26,376 | |
0.00858 % | State Street Global Advisors Ireland Limited | 31,839 | 4,200 | |
0.00840 % | Charles Schwab Investment Management, Inc. | 31,192 | 0 | |
0.00830 % | SEI Investments Management Corporation | 30,800 | -2,999 | |
0.00790 % | BlackRock Investment Management, LLC | 29,326 | 15,539 | |
0.00749 % | EverSource Wealth Advisors, LLC | 27,800 | 0 | |
0.00736 % | Cubist Systematic Strategies, LLC | 27,310 | 21,137 | |
0.00722 % | T. Rowe Price International Ltd | 26,800 | -11,600 | |
0.00711 % | American Century Investment Management, Inc. | 26,387 | 25,055 | |
0.00704 % | XTX Markets LLC | 26,130 | 26,130 | |
0.00685 % | BlackRock Investment Management (UK) Ltd. | 25,425 | 25,425 | |
0.00665 % | Dynamic Technology Lab Pte. Ltd. | 24,677 | 24,677 | |
0.00655 % | Mercer Global Investments Management Ltd | 24,309 | 24,309 | |
0.00632 % | Marshall Wace LLP | 23,472 | 0 | |
0.00632 % | Osaic Holdings, Inc. | 23,444 | -24,136 | |