7.47976 % | Avoro Capital Advisors LLC | 5,666,666 | 0 | |
7.28115 % | Fidelity Management & Research Company LLC | 5,516,202 | 505 | |
6.92984 % | Capital Research Global Investors | 5,250,043 | 93,377 | |
5.83352 % | Driehaus Capital Management, LLC | 4,419,472 | 97,732 | |
5.05309 % | Wellington Management Company, LLP | 3,828,221 | -93,837 | |
3.63551 % | Commodore Capital LP | 2,754,266 | 586,473 | |
3.53952 % | Capital World Investors | 2,681,537 | 0 | |
3.37985 % | Braidwell LP | 2,560,573 | 1,252,562 | |
3.34749 % | Polar Capital LLP | 2,536,058 | -76,050 | |
3.26803 % | Capital International Investors | 2,475,859 | 0 | |
2.69704 % | Paradigm BioCapital Advisors LP | 2,043,280 | -441,594 | |
2.42813 % | Adage Capital Management, L.P. | 1,839,555 | 167,638 | |
1.95772 % | AllianceBernstein L.P. | 1,483,166 | 14,720 | |
1.95287 % | Pictet Asset Management Ltd. | 1,479,491 | -35,935 | |
1.90061 % | T. Rowe Price Investment Management, Inc. | 1,439,903 | 13,564 | |
1.82771 % | Marshall Wace LLP | 1,384,674 | -65,668 | |
1.72421 % | First Light Asset Management, LLC | 1,306,260 | -13,912 | |
1.68014 % | Rock Springs Capital Management LP | 1,272,877 | 17,300 | |
1.65255 % | Fidelity Institutional Asset Management | 1,251,971 | 165,838 | |
1.37970 % | Janus Henderson Investors | 1,045,257 | 103,688 | |
1.31234 % | Affinity Asset Advisors LLC | 994,227 | 156,840 | |
1.31161 % | Baker Bros. Advisors LP | 993,679 | 0 | |
1.27979 % | BlackRock Financial Management, Inc. | 969,569 | 46,032 | |
1.13828 % | OrbiMed Advisors, LLC | 862,362 | 312,362 | |
1.02959 % | Invesco Advisers, Inc. | 780,016 | -25,650 | |
1.01469 % | Citadel Advisors LLC | 768,726 | -518,349 | |
0.99590 % | TimesSquare Capital Management, LLC | 754,493 | 17,320 | |
0.99525 % | Avidity Partners Management LP | 754,000 | 44,000 | |
0.99194 % | BlackRock Institutional Trust Company, N.A. | 751,490 | 14,390 | |
0.96958 % | Federated Hermes Global Investment Management Corp. | 734,555 | -345 | |
0.87151 % | Loomis, Sayles & Company, L.P. | 660,258 | -26,252 | |
0.84945 % | Westfield Capital Management Company, L.P. | 643,546 | 296,195 | |
0.84436 % | Samlyn Capital, LLC | 639,685 | 243,489 | |
0.79197 % | Boxer Capital, L.L.C. | 600,000 | 0 | |
0.76987 % | Perceptive Advisors LLC | 583,256 | -308,952 | |
0.75793 % | Fiera Capital Inc. | 574,211 | 3,893 | |
0.75273 % | Jennison Associates LLC | 570,272 | 6,320 | |
0.69298 % | Vestal Point Capital, LP | 525,000 | 125,000 | |
0.68880 % | Candriam Belgium S.A. | 521,836 | -39,048 | |
0.63625 % | Point72 Asset Management, L.P. | 482,022 | 206,163 | |
0.61228 % | Candriam Luxembourg S.A. | 463,861 | 0 | |
0.57611 % | Dimensional Fund Advisors, L.P. | 436,460 | 26,253 | |
0.53330 % | Two Sigma Investments, LP | 404,029 | -99,797 | |
0.50694 % | BNP Paribas Asset Management USA, Inc. | 384,058 | 2,605 | |
0.50364 % | Invus Public Equities Advisors, LLC | 381,554 | 128,167 | |
0.49498 % | Logos Global Management LLC | 375,000 | 375,000 | |
0.48288 % | Norges Bank Investment Management (NBIM) | 365,830 | 231,372 | |
0.47598 % | Altium Capital Management LP | 360,600 | 12,600 | |
0.47146 % | ExodusPoint Capital Management, LP | 357,178 | 203,140 | |
0.44862 % | First Turn Management, LLC | 339,876 | -340,513 | |
0.43878 % | Goldman Sachs & Company, Inc. | 332,421 | 62,757 | |
0.43313 % | The Vanguard Group, Inc. | 328,143 | 5,517 | |
0.42414 % | Medical Strategy GmbH | 321,332 | -4,600 | |
0.38784 % | Franklin Advisers, Inc. | 293,825 | 0 | |
0.38525 % | Alyeska Investment Group, L.P. | 291,868 | 53,025 | |
0.37624 % | Putnam Investment Management, L.L.C. | 285,040 | 36,576 | |
0.36132 % | Dafna Capital Management, LLC | 273,739 | 0 | |
0.33060 % | Boone Capital Management LLC | 250,460 | -40,943 | |
0.32776 % | abrdn Inc. | 248,311 | 35,809 | |
0.32578 % | State Street Global Advisors (US) | 246,812 | 4,172 | |
0.30799 % | Balyasny Asset Management LP | 233,335 | 32,061 | |
0.29853 % | Granahan Investment Management, LLC | 226,166 | -17,914 | |
0.29710 % | Morgan Stanley & Co. LLC | 225,082 | -141,640 | |
0.28021 % | Assenagon Asset Management S.A. | 212,287 | 138,685 | |
0.27625 % | Parkman Healthcare Partners LLC | 209,290 | -14,652 | |
0.25084 % | Lord, Abbett & Co. LLC | 190,033 | -705,163 | |
0.24820 % | AXA Investment Managers UK Ltd. | 188,038 | 166 | |
0.24182 % | Algert Global LLC | 183,205 | -810 | |
0.23196 % | DNB Asset Management AS | 175,733 | 49,483 | |
0.23176 % | Millennium Management LLC | 175,584 | 91,923 | |
0.22597 % | Laurion Capital Management LP | 171,195 | -67,931 | |
0.22405 % | BlackRock Investment Management (UK) Ltd. | 169,738 | 54,944 | |
0.22356 % | Ally Bridge Group NY LLC | 169,369 | -140,000 | |
0.21524 % | Ensign Peak Advisors, Inc. | 163,064 | 0 | |
0.21347 % | D. E. Shaw & Co., L.P. | 161,722 | -36,804 | |
0.21268 % | BlackRock Advisors (UK) Limited | 161,124 | 1,456 | |
0.20880 % | Russell Investments Trust Company | 158,185 | -15,021 | |
0.19931 % | Nomura Asset Management Co., Ltd. | 151,000 | -34,400 | |
0.19872 % | PFM Health Sciences, LP | 150,554 | 0 | |
0.19377 % | Bridger Management, LLC | 146,800 | 0 | |
0.18052 % | BlackRock Asset Management Ireland Limited | 136,761 | -155,554 | |
0.17492 % | New York State Common Retirement Fund | 132,521 | -18,319 | |
0.16645 % | Schweizerische Nationalbank | 126,100 | 2,300 | |
0.16367 % | Atika Capital Management LLC | 124,000 | 2,000 | |
0.14900 % | Polen Capital Management, LLC | 112,881 | 25,782 | |
0.14526 % | Tenax Capital Ltd. | 110,047 | 0 | |
0.14148 % | Ikarian Capital LLC | 107,187 | 0 | |
0.14081 % | Nan Fung Life Sciences | 106,680 | 0 | |
0.13458 % | Tri Locum Partners LP | 101,959 | -105,506 | |
0.13213 % | Baron Capital Management, Inc. | 100,100 | 0 | |
0.12759 % | Principal Global Investors (Equity) | 96,662 | -6,920 | |
0.12262 % | Renaissance Technologies LLC | 92,900 | 36,500 | |
0.12078 % | Schroder Investment Management Ltd. (SIM) | 91,500 | 0 | |
0.12078 % | International Biotechnology Trust PLC | 91,500 | 66,000 | |
0.11853 % | State of Wisconsin Investment Board | 89,800 | -1,985 | |
0.11709 % | TwinBeech Capital LP | 88,711 | -9,331 | |
0.11651 % | MFS Investment Management | 88,267 | -704 | |
0.11163 % | New Jersey Division of Investment | 84,573 | -8,177 | |
0.10956 % | Victory Capital Management Inc. | 82,999 | -14,354 | |
0.09890 % | Neuberger Berman, LLC | 74,926 | 12,896 | |