7.55367 % | Citadel Advisors LLC | 5,388,789 | 2,031,549 | |
7.34562 % | BlackRock Institutional Trust Company, N.A. | 5,240,367 | 369,372 | |
6.60592 % | The Vanguard Group, Inc. | 4,712,661 | 1,359,311 | |
5.28445 % | Millennium Management LLC | 3,769,926 | 290,565 | |
4.90608 % | Bain Capital Life Sciences Investors, LLC | 3,500,000 | 100,000 | |
4.20310 % | Rock Springs Capital Management LP | 2,998,495 | 0 | |
4.04326 % | Two Sigma Investments, LP | 2,884,461 | 2,712,561 | |
3.29606 % | Acadian Asset Management LLC | 2,351,407 | 2,351,407 | |
2.71798 % | D. E. Shaw & Co., L.P. | 1,939,010 | 1,873,000 | |
2.46929 % | Velan Capital Investment Management LP | 1,761,595 | 1,761,595 | |
2.45772 % | Tang Capital Management, LLC | 1,753,335 | -2,584,820 | |
2.44804 % | Renaissance Technologies LLC | 1,746,432 | 1,098,780 | |
2.35479 % | Qube Research & Technologies Ltd | 1,679,905 | 1,679,905 | |
2.22595 % | GSA Capital Partners LLP | 1,587,995 | 1,550,026 | |
13.17064 % | BML Capital Management LLC | 9,395,934 | 4,895,934 | |
1.95339 % | Geode Capital Management, L.L.C. | 1,393,548 | 56,466 | |
1.94623 % | State Street Global Advisors (US) | 1,388,439 | -174,069 | |
1.80220 % | Walker Neal | 1,285,688 | 6,243 | |
1.37286 % | Monaco asset management S.A.M. | 979,399 | 979,399 | |
1.30460 % | DWS Investments UK Limited | 930,699 | 893,681 | |
1.28358 % | Morgan Stanley & Co. LLC | 915,709 | -422,092 | |
1.04959 % | Jacobs Levy Equity Management, Inc. | 748,775 | 573,294 | |
0.97585 % | Samsara BioCapital, LLC | 696,171 | 0 | |
0.89482 % | Fidelity Management & Research Company LLC | 638,365 | 9,414 | |
0.81268 % | Northern Trust Investments, Inc. | 579,765 | 15,457 | |
0.71139 % | Citi Investment Research (US) | 507,508 | 495,644 | |
0.66004 % | Goldman Sachs & Company, Inc. | 470,871 | 321,925 | |
0.63585 % | Checkpoint Capital L.P. | 453,614 | 453,614 | |
0.61452 % | Nuveen LLC | 438,400 | -21,913 | |
0.61162 % | Charles Schwab Investment Management, Inc. | 436,330 | -26,904 | |
0.60899 % | Aisling Capital Management LP | 434,455 | 0 | |
0.53028 % | XTX Markets LLC | 378,300 | 378,300 | |
0.48083 % | Hightower Advisors, LLC | 343,024 | -26,778 | |
0.37059 % | Frazier Healthcare Partners | 264,377 | 0 | |
0.36359 % | Jane Street Capital, L.L.C. | 259,384 | 95,324 | |
0.33906 % | BNY Mellon Asset Management | 241,884 | 39,731 | |
0.30467 % | BNP Paribas Securities Corp. North America | 217,354 | 140,744 | |
0.28421 % | BlackRock Financial Management, Inc. | 202,757 | -58,691 | |
0.28299 % | Ruffo (Frank) | 201,883 | 0 | |
0.28035 % | ACCI Capital Investments SGIIC, SA | 200,000 | -280,000 | |
0.27054 % | State Teachers Retirement System of Ohio | 193,000 | 138,900 | |
0.26290 % | Dimensional Fund Advisors, L.P. | 187,553 | -74,180 | |
0.26209 % | Monahan (Joseph B) | 186,976 | 52,142 | |
0.25536 % | BlackRock Investment Management, LLC | 182,175 | -7,802 | |
0.25084 % | BlackRock Asset Management Ireland Limited | 178,948 | 32,100 | |
0.24659 % | Barclays Bank PLC | 175,918 | -45,799 | |
0.21532 % | Susquehanna International Group, LLP | 153,609 | 29,759 | |
0.20802 % | Endurant Capital Management LP | 148,400 | 148,400 | |
0.19012 % | Credit Suisse Funds AG | 135,629 | 36,522 | |
0.18965 % | Cubist Systematic Strategies, LLC | 135,295 | 92,271 | |
0.17576 % | BofA Global Research (US) | 125,387 | 73,689 | |
0.16246 % | Lion Point Capital, L.P. | 115,898 | 0 | |
0.15265 % | Schweizerische Nationalbank | 108,900 | 0 | |
0.15211 % | T. Rowe Price International Ltd | 108,515 | 53,658 | |
0.14197 % | Numeric Investors LLC | 101,280 | 7,894 | |
0.14017 % | Octagon Capital Advisors LP | 100,000 | 100,000 | |
0.13422 % | Rhumbline Advisers Ltd. Partnership | 95,750 | -6,684 | |
0.11184 % | Engineers Gate Manager, L.P. | 79,789 | 54,319 | |
0.11138 % | UBS Asset Management (Switzerland) | 79,456 | 0 | |
0.10822 % | Group One Trading, L.P. | 77,201 | 8,911 | |
0.10364 % | Wellington Management Japan Pte Ltd | 73,939 | 73,939 | |
0.09078 % | Columbia Threadneedle Investments (US) | 64,760 | -12,755 | |
0.08466 % | AllianceBernstein L.P. | 60,400 | 0 | |
0.07788 % | California State Teachers Retirement System | 55,559 | -3,488 | |
0.07449 % | Parametric Portfolio Associates LLC | 53,138 | -37,494 | |
0.07010 % | Goldman Sachs Asset Management, L.P. | 50,009 | -61,185 | |
0.07007 % | JPMorgan Private Bank (United States) | 49,991 | 28,197 | |
0.06994 % | Legal & General Investment Management Ltd. | 49,895 | 0 | |
0.06799 % | Molineaux (Christopher P) | 48,503 | 21,256 | |
0.06546 % | Northern Trust Global Investments | 46,697 | -14,446 | |
0.06137 % | Zürcher Kantonalbank (Asset Management) | 43,784 | 23,467 | |
0.05899 % | BlackRock Advisors (UK) Limited | 42,080 | -21,833 | |
0.05869 % | Cambridge Investment Research Advisors, Inc. | 41,873 | 26,535 | |
0.05861 % | Manion (Douglas J) | 41,813 | 17,875 | |
0.05675 % | Mellon Investments Corporation | 40,487 | 0 | |
0.05607 % | Abaris Investment Management AG | 40,000 | -16,000 | |
0.05465 % | BlackRock Investment Management (UK) Ltd. | 38,990 | -6,418 | |
0.05425 % | Mehra Anand | 38,704 | 4,507 | |
0.05138 % | Mariner Wealth Advisors | 36,657 | 36,657 | |
0.04839 % | SunAmerica Asset Management, LLC | 34,523 | -138 | |
0.04786 % | UBS Asset Management (UK) Ltd. | 34,145 | 0 | |
0.04768 % | Loerop (James) | 34,017 | 12,329 | |
0.04651 % | Tudor Investment Corporation | 33,183 | 0 | |
0.04650 % | Northern Trust Global Investments Limited | 33,175 | -745 | |
0.04534 % | Fidelity Institutional Asset Management | 32,349 | 0 | |
0.04408 % | BlackRock (Netherlands) B.V. | 31,446 | 22,431 | |
0.04343 % | Harbor Capital Advisors, Inc. | 30,984 | 325 | |
0.04274 % | Aperio Group, LLC | 30,492 | -8,556 | |
0.04243 % | Bank Vontobel AG | 30,268 | 17,040 | |
0.04113 % | Point72 Asset Management, L.P. | 29,344 | -643,877 | |
0.04104 % | Invesco Advisers, Inc. | 29,275 | -3,880 | |
0.04046 % | Powell (Andrew Kenneth William) | 28,863 | 14,500 | |
0.03813 % | Virginia Retirement System | 27,200 | 27,200 | |
0.03374 % | Humphries (William Douglas) | 24,072 | 4,507 | |
0.03374 % | Reasons (Bryan M) | 24,072 | 4,507 | |
0.03362 % | Balthaser (Kevin J) | 23,983 | 3,558 | |
0.03084 % | Deka Investment GmbH | 22,000 | 0 | |
0.02942 % | Chicago Partners Wealth Advisors | 20,988 | 20,988 | |
0.02846 % | Janus Henderson Investors | 20,300 | -53 | |
0.02817 % | Florida State Board of Administration | 20,094 | 0 | |