5.57500 % | Shionogi & Co Ltd | 3,500,000 | 0 | |
2.91493 % | Nomura Asset Management Co., Ltd. | 1,830,000 | 6,800 | |
2.73458 % | Nomura Securities Co., Ltd. | 1,716,778 | 622,000 | |
2.56132 % | Toho Holdings Company Ltd. Employees | 1,608,000 | -97,000 | |
2.44026 % | The Vanguard Group, Inc. | 1,532,003 | 132,500 | |
2.12392 % | Norges Bank Investment Management (NBIM) | 1,333,399 | 665,709 | |
2.12328 % | Kawano (Hiroyuki) | 1,333,000 | 0 | |
2.02803 % | Dimensional Fund Advisors, L.P. | 1,273,200 | 18,600 | |
1.83019 % | Morgan Stanley MUFG Securities Co., Ltd. | 1,149,000 | 1,149,000 | |
1.50748 % | BlackRock Institutional Trust Company, N.A. | 946,400 | 18,200 | |
1.48782 % | Tsumura & Co | 934,060 | 0 | |
1.30596 % | Nikko Asset Management Co., Ltd. | 819,884 | 5,100 | |
1.26519 % | Daiwa Asset Management Co., Ltd. | 794,290 | 1,496 | |
1.21376 % | Taisho Pharmaceutical Holdings Co Ltd | 762,000 | 0 | |
0.92135 % | Sumitomo Pharma Co Ltd | 578,426 | 0 | |
0.76819 % | Nomura International Plc. | 482,269 | 404,969 | |
0.64957 % | Avantis Investors | 407,800 | -35,200 | |
0.63611 % | Ono Pharmaceutical Co Ltd | 399,350 | 0 | |
0.57837 % | Charles Schwab Investment Management, Inc. | 363,099 | 90,768 | |
0.56798 % | Kissei Pharmaceutical Co Ltd | 356,581 | 0 | |
0.51840 % | Nippon Shinyaku Co Ltd | 325,453 | 0 | |
0.45986 % | Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 288,702 | -140,501 | |
0.38770 % | Mochida Pharmaceutical Co Ltd | 243,400 | 0 | |
0.29707 % | Kobayashi Pharmaceutical Co Ltd | 186,500 | -21,200 | |
0.29436 % | Goldman Sachs Asset Management, L.P. | 184,800 | 170,700 | |
0.29372 % | Baillie Gifford & Co. | 184,400 | 40,200 | |
0.23065 % | Yakult Honsha Co Ltd | 144,800 | 0 | |
0.20259 % | California State Teachers Retirement System | 127,186 | 19,400 | |
0.19446 % | Terumo Corp | 122,080 | 0 | |
0.16923 % | BlackRock Advisors (UK) Limited | 106,246 | 1,100 | |
0.15244 % | Dimensional Fund Advisors, Ltd. | 95,700 | 500 | |
0.14973 % | Fuso Pharmaceutical Industries Ltd | 94,000 | 0 | |
0.14192 % | Jupiter Asset Management Ltd. | 89,100 | -58,600 | |
0.13253 % | Nippon Kayaku Co Ltd | 83,200 | 0 | |
0.13215 % | Hisamitsu Pharmaceutical Co Inc | 82,962 | 0 | |
0.11625 % | Asset Management One Co., Ltd. | 72,983 | 100 | |
0.10999 % | Santen Pharmaceutical Co Ltd | 69,050 | -61,000 | |
0.07809 % | Wakamoto Pharmaceutical Co Ltd | 49,022 | 0 | |
0.07584 % | CI Global Asset Management | 47,612 | 6,068 | |
0.06945 % | Macquarie Investment Management | 43,600 | 0 | |
0.06743 % | Nuveen LLC | 42,330 | 0 | |
0.06491 % | Kaken Pharmaceutical Co Ltd | 40,750 | 0 | |
0.05989 % | American Century Investment Management, Inc. | 37,600 | 0 | |
0.05918 % | Florida State Board of Administration | 37,156 | 123 | |
0.05543 % | Geode Capital Management, L.L.C. | 34,800 | 0 | |
0.04960 % | SEI Investments Management Corporation | 31,138 | -6,090 | |
0.04384 % | Kimura Unity Co Ltd | 27,525 | 0 | |
0.04237 % | UBS Asset Management (UK) Ltd. | 26,600 | 0 | |
0.04045 % | Credit Suisse Funds AG | 25,393 | 0 | |
0.04030 % | State Street Global Advisors (US) | 25,300 | 0 | |
0.03209 % | Invesco Capital Management LLC | 20,145 | 0 | |
0.03154 % | Norinchukin Zenkyoren Asset Management Co., Ltd. | 19,800 | 1,300 | |
0.02979 % | Thrivent Asset Management, LLC | 18,700 | 0 | |
0.02692 % | PIMCO (US) | 16,900 | 300 | |
0.02628 % | KLP Fondsforvaltning AS | 16,500 | 7,400 | |
0.02580 % | Mercer Global Investments Management Ltd | 16,200 | 0 | |
0.02437 % | Pzena Investment Management, LLC | 15,300 | -8,700 | |
0.02278 % | Mellon Investments Corporation | 14,300 | -4,800 | |
0.02201 % | Northern Trust Global Investments Limited | 13,820 | -1,200 | |
0.02198 % | Parametric Portfolio Associates LLC | 13,800 | 0 | |
0.01975 % | Zürcher Kantonalbank (Asset Management) | 12,400 | 0 | |
0.01934 % | Vanguard Investments Australia Ltd. | 12,140 | -2 | |
0.01832 % | Goldman Sachs Asset Management B.V. | 11,500 | 0 | |
0.01816 % | BlackRock Investment Management (UK) Ltd. | 11,400 | 0 | |
0.01768 % | PineStone Asset Management Inc. | 11,100 | 0 | |
0.01577 % | BlackRock Asset Management Canada Limited | 9,900 | 0 | |
0.01529 % | HAC VermögensManagement AG | 9,600 | 0 | |
0.01516 % | Amundi Asset Management, SAS | 9,518 | 1,900 | |
0.01497 % | Research Affiliates, LLC | 9,400 | 0 | |
0.01465 % | Russell Investments Limited | 9,200 | 0 | |
0.01407 % | DFA Australia Ltd. | 8,831 | 11 | |
0.01322 % | Grantham Mayo Van Otterloo & Co LLC | 8,300 | 0 | |
0.01257 % | Nippon Chemiphar Co Ltd | 7,890 | 0 | |
0.00957 % | Mackenzie Financial Corporation | 6,006 | -860 | |
0.00924 % | Simplex Asset Management Co., Ltd. | 5,800 | -200 | |
0.00888 % | Sumitomo Mitsui DS Asset Management Company, Limited | 5,572 | 362 | |
0.00860 % | Legal & General Investment Management Ltd. | 5,400 | 0 | |
0.00796 % | Acadian Asset Management LLC | 5,000 | 0 | |
0.00796 % | Nissay Asset Management Corp. | 4,998 | -350 | |
0.00792 % | AllianceBernstein L.P. | 4,972 | 0 | |
0.00765 % | BlackRock Financial Management, Inc. | 4,800 | 4,800 | |
0.00626 % | BBVA Asset Management, S.A., S.G.I.I.C. | 3,932 | 671 | |
0.00621 % | Pictet Asset Management Ltd. | 3,900 | 2,200 | |
0.00573 % | Eurizon Capital S.A. | 3,600 | 300 | |
0.00442 % | Sompo Asset Management Co.,Ltd. | 2,772 | -68 | |
0.00430 % | WBS Hünicke Vermögensverwaltung GmbH | 2,700 | 2,700 | |
0.00414 % | Schroder Investment Management Ltd. (SIM) | 2,600 | 2,600 | |
0.00398 % | UBS Hana Asset Management Company Ltd. | 2,500 | -500 | |
0.00366 % | Boston Partners | 2,300 | 0 | |
0.00335 % | SEI Investments Canada | 2,100 | 2,100 | |
0.00335 % | State Street Global Advisors Ireland Limited | 2,100 | 0 | |
0.00319 % | Vanguard Global Advisers LLC | 2,000 | 1,100 | |
0.00303 % | UBS Asset Management (Switzerland) | 1,900 | 0 | |
0.00303 % | Harris Associates L.P. | 1,900 | 0 | |
0.00239 % | First Trust Advisors L.P. | 1,500 | 0 | |
0.00175 % | Dimensional Fund Advisors Canada ULC | 1,100 | 0 | |
0.00175 % | Victory Capital Management Inc. | 1,100 | 0 | |
0.00101 % | Meiji Yasuda Asset Management Company Ltd. | 633 | 1 | |
0.00071 % | Sumitomo Mitsui DS Asset Management (Hong Kong) Limited | 445 | -75 | |
0.00064 % | Shinkin Asset Management Co., Ltd. | 400 | 0 | |