9.34358 % | Invus Public Equities Advisors, LLC | 2,505,013 | 1,029,269 | |
7.72814 % | Adage Capital Management, L.P. | 2,071,914 | 1,350,000 | |
6.66329 % | Samsara BioCapital, LLC | 1,786,427 | 904,977 | |
6.24222 % | Avidity Partners Management LP | 1,673,538 | 92,396 | |
5.56976 % | Blue Owl Capital Holdings LP | 1,493,252 | 1,493,252 | |
5.48963 % | Point72 Asset Management, L.P. | 1,471,771 | 1,471,771 | |
4.84655 % | Cowen Investment Management LLC | 1,299,359 | 531,914 | |
4.82599 % | Flagship Ventures | 1,293,848 | 300,000 | |
3.09021 % | Deep Track Capital LP | 828,485 | 0 | |
2.85271 % | The Vanguard Group, Inc. | 764,812 | 236,620 | |
10.25665 % | Bain Capital Life Sciences Investors, LLC | 2,749,808 | 625,114 | |
1.98401 % | TD Cowen | 531,914 | 531,914 | |
1.68531 % | Medical Strategy GmbH | 451,832 | -76,358 | |
1.34043 % | Opaleye Management Inc. | 359,370 | 359,370 | |
0.93722 % | Omega Fund Management, LLC | 251,270 | 0 | |
0.90008 % | BlackRock Institutional Trust Company, N.A. | 241,311 | 1,590 | |
0.89400 % | Goldman Sachs & Company, Inc. | 239,681 | 133,149 | |
0.80151 % | Dafna Capital Management, LLC | 214,885 | -50,993 | |
0.60262 % | Geode Capital Management, L.L.C. | 161,563 | 23,698 | |
0.55076 % | Simonian (Nancy A) | 147,658 | -14,052 | |
0.48489 % | UBS O'Connor LLC | 130,000 | 130,000 | |
0.38613 % | ExodusPoint Capital Management, LP | 103,522 | -4,615 | |
0.31716 % | Tang Capital Management, LLC | 85,031 | 85,031 | |
0.31332 % | EAM Investors, LLC | 84,002 | 84,002 | |
0.30408 % | LPL Financial LLC | 81,525 | -8,650 | |
0.29812 % | Knott Partners Management, LLC | 79,927 | -26,048 | |
0.21871 % | Renaissance Technologies LLC | 58,635 | 9,400 | |
0.20515 % | LGT Capital Partners Ltd. | 55,000 | 0 | |
0.20386 % | Two Sigma Investments, LP | 54,654 | 54,654 | |
0.18437 % | State Street Global Advisors (US) | 49,430 | 16,300 | |
0.14906 % | Northern Trust Investments, Inc. | 39,963 | 13,576 | |
0.14829 % | Quirk (Gerald E.) | 39,757 | 15,454 | |
0.14733 % | Bridgeway Capital Management, LLC | 39,500 | 0 | |
0.14486 % | Young (Richard A) | 38,837 | 2,666 | |
0.13593 % | 683 Capital Management LLC | 36,444 | 36,444 | |
0.10887 % | Tyson (Timothy C.) | 29,189 | 4,000 | |
0.09413 % | Stephens (Kristin) | 25,237 | -4,218 | |
0.09373 % | Assenagon Asset Management S.A. | 25,130 | 0 | |
0.09257 % | Marshall Wace LLP | 24,818 | 24,818 | |
0.09158 % | Haas (Jason) | 24,552 | -4,732 | |
0.08411 % | T. Rowe Price International Ltd | 22,550 | 0 | |
0.08411 % | T. Rowe Price Associates, Inc. | 22,550 | 0 | |
0.08394 % | Chee (Conley) | 22,504 | -3,500 | |
0.08110 % | 1492 Capital Management, LLC | 21,744 | 0 | |
0.07883 % | Jane Street Capital, L.L.C. | 21,135 | 21,135 | |
0.06945 % | The Clarius Group, LLC | 18,620 | 0 | |
0.05743 % | CIBC Asset Management Inc. | 15,398 | 0 | |
0.05596 % | Hightower Advisors, LLC | 15,004 | 0 | |
0.05082 % | Avantis Investors | 13,624 | 13,624 | |
0.04476 % | Fanucci (Marsha H) | 12,000 | 4,000 | |
0.04476 % | Wirth (Peter) | 12,000 | 4,000 | |
0.04476 % | Corient Private Wealth LLC | 12,000 | -14,666 | |
0.04476 % | Eckhardt (Sue Gail) | 12,000 | 4,000 | |
0.04476 % | Oh (Andrew M.) | 12,000 | 4,000 | |
0.04105 % | XTX Markets LLC | 11,006 | 11,006 | |
0.03921 % | Y-Intercept (Hong Kong) Ltd | 10,512 | 10,512 | |
0.03738 % | BofA Global Research (US) | 10,021 | 9,953 | |
0.03730 % | Integrated Financial Partners | 10,000 | 10,000 | |
0.02984 % | Dunsire (Deborah) | 8,000 | 7,200 | |
0.02485 % | Olson (Eric R.) | 6,661 | -689 | |
0.02305 % | Citadel Advisors LLC | 6,180 | 6,180 | |
0.01742 % | Charles Schwab Investment Management, Inc. | 4,670 | 0 | |
0.01634 % | Edmond de Rothschild Asset Management (France) S.A. | 4,382 | 0 | |
0.01367 % | Alles (Mark J) | 3,666 | 2,666 | |
0.01305 % | ACT Capital Management, L.L.C. | 3,499 | -1 | |
0.01216 % | BlackRock Investment Management, LLC | 3,259 | -391 | |
0.01119 % | RBC Capital Partners | 3,000 | 2,058 | |
0.00994 % | Akkaraju (Srinivas) | 2,666 | 0 | |
0.00866 % | BlackRock Financial Management, Inc. | 2,322 | 0 | |
0.00746 % | Pharus Management Lux SA | 2,000 | 0 | |
0.00477 % | Group One Trading, L.P. | 1,279 | 0 | |
0.00445 % | Morgan Stanley & Co. LLC | 1,192 | -1,481 | |
0.00419 % | First Capital Advisors Group, LLC | 1,123 | 1,123 | |
0.00408 % | PNC Investments LLC | 1,095 | 0 | |
0.00404 % | Osaic Holdings, Inc. | 1,083 | 787 | |
0.00280 % | Russell Investments Trust Company | 750 | 0 | |
0.00246 % | Rhumbline Advisers Ltd. Partnership | 659 | 0 | |
0.00179 % | J.P. Morgan Securities LLC | 481 | 0 | |
0.00163 % | Independent Financial Partners | 438 | 0 | |
0.00159 % | Morgan Stanley Smith Barney LLC | 427 | -1,598 | |
0.00153 % | Wells Fargo Advisors | 411 | -108 | |
0.00115 % | Mackenzie Financial Corporation | 307 | -40 | |
0.00106 % | Manulife Investment Management (North America) Limited | 285 | 0 | |
0.00048 % | MainStreet Advisors | 129 | 0 | |
0.00048 % | Wells Fargo Bank, N.A. | 129 | 7 | |
0.00028 % | Sound Income Strategies, LLC | 76 | 0 | |
0.00025 % | J.P. Morgan Securities plc | 68 | -528 | |
0.00019 % | Aperio Group, LLC | 52 | 0 | |
0.00015 % | Blackstone Alternative Investment Advisors LLC | 40 | 40 | |
0.00013 % | Guggenheim Investments | 34 | 0 | |
0.00005 % | Concept Asset Management | 13 | 0 | |
0.00005 % | PSI Advisors, L.L.C. | 13 | 13 | |
0.00003 % | Steward Partners Investment Advisory, LLC | 8 | 8 | |
0.00003 % | Northern Trust Global Investments | 7 | 0 | |
0 % | Altium Capital Management LP | 0 | -315,070 | |
0 % | Qube Research & Technologies Ltd | 0 | -5,357 | |
0 % | Shay Capital LLC | 0 | -23,776 | |
0 % | Bogart Wealth, LLC | 0 | -15 | |
0 % | Ergoteles Capital | 0 | -18,181 | |
0 % | Schonfeld Strategic Advisors LLC | 0 | -3,011 | |