18.79420 % | Casdin Capital, LLC | 69,754,677 | 5,795,000 | |
15.80255 % | Viking Global Investors LP | 58,651,170 | 0 | |
5.28097 % | BlackRock Institutional Trust Company, N.A. | 19,600,313 | 14,639,205 | |
4.29751 % | The Vanguard Group, Inc. | 15,950,204 | 2,969,115 | |
3.41624 % | ARK Investment Management LLC | 12,679,391 | -363,049 | |
3.36179 % | Morgan Stanley Investment Management Inc. (US) | 12,477,283 | 5,488,609 | |
2.86738 % | Nikko Asset Management Co., Ltd. | 10,642,271 | 1,788,780 | |
1.88178 % | Millennium Management LLC | 6,984,232 | 762,239 | |
1.83076 % | Geode Capital Management, L.L.C. | 6,794,869 | 4,087,943 | |
1.76507 % | Tikvah Management LLC | 6,551,058 | 0 | |
1.16857 % | State Street Global Advisors (US) | 4,337,152 | 2,995,795 | |
1.11471 % | Neuberger Berman, LLC | 4,137,246 | -607,677 | |
0.81063 % | PRIMECAP Management Company | 3,008,643 | -13,200 | |
0.76818 % | Barclays Bank PLC | 2,851,093 | -1,010,957 | |
0.75449 % | Casdin (Eli) | 2,800,302 | 2,500,327 | |
0.50739 % | Nan Fung Life Sciences | 1,883,179 | 0 | |
0.43513 % | Slate Path Capital LP | 1,615,000 | 0 | |
0.40482 % | Egholm Michael | 1,502,499 | -29,093 | |
0.33117 % | Qube Research & Technologies Ltd | 1,229,132 | -487,835 | |
0.27066 % | Renaissance Technologies LLC | 1,004,558 | -249,300 | |
0.26894 % | Balyasny Asset Management LP | 998,162 | -3,846,889 | |
0.26524 % | Needham Investment Management L.L.C. | 984,435 | -140,000 | |
0.26407 % | MFP Investors, LLC | 980,100 | 0 | |
0.25599 % | Invenomic Capital Management LP | 950,114 | 386,359 | |
0.24393 % | Citadel Advisors LLC | 905,346 | 905,346 | |
0.24209 % | Gagnon Securities LLC | 898,509 | 43,364 | |
0.23800 % | BlackRock Investment Management, LLC | 883,333 | 837,194 | |
0.22997 % | BlackRock Financial Management, Inc. | 853,551 | 776,034 | |
0.22831 % | Charles Schwab Investment Management, Inc. | 847,355 | 735,771 | |
0.22526 % | Northern Trust Investments, Inc. | 836,068 | 225,585 | |
0.21101 % | Nuveen LLC | 783,152 | 783,152 | |
0.19102 % | BNY Mellon Asset Management | 708,960 | 621,361 | |
0.18672 % | Magnetar Capital Partners LP | 692,998 | -822,392 | |
0.18114 % | Gagnon Advisors, LLC | 672,294 | 0 | |
0.16166 % | Mackay (Sean) | 600,000 | 600,000 | |
0.15129 % | Walleye Capital LLC | 561,521 | 561,521 | |
0.14880 % | Kim Hanjoon Alex | 552,262 | 333,333 | |
0.14819 % | Paradigm Capital Management, Inc. | 550,000 | 0 | |
0.13171 % | Schweizerische Nationalbank | 488,860 | 60,200 | |
0.13044 % | Goldman Sachs & Company, Inc. | 484,125 | -2,761,220 | |
0.12642 % | Two Sigma Investments, LP | 469,191 | -263,223 | |
0.11556 % | Azimut Capital Management Sgr SpA | 428,900 | 0 | |
0.11360 % | Black (Jeffrey G) | 421,608 | 1,772 | |
0.11308 % | Intellectus Partners, LLC | 419,702 | -3,816 | |
0.11091 % | Redmile Group, LLC | 411,631 | 0 | |
0.10978 % | Rhumbline Advisers Ltd. Partnership | 407,467 | 396,719 | |
0.10028 % | Morgan Stanley & Co. LLC | 372,177 | -26,276 | |
0.09764 % | Dimensional Fund Advisors, L.P. | 362,385 | -904,474 | |
0.08924 % | Neuberger Berman Asset Management Ireland Ltd | 331,203 | 0 | |
0.08506 % | AllianceBernstein L.P. | 315,690 | 315,690 | |
0.08487 % | Nahum (Benjamin H) | 315,000 | 315,000 | |
0.08411 % | ARIAD Asset Management GmbH | 312,180 | 0 | |
0.08405 % | Johnson & Johnson Innovation-JJDC, Inc. | 311,967 | 0 | |
0.08352 % | Sempione SIM SpA | 310,000 | 80,000 | |
0.08232 % | Squarepoint Capital LLP | 305,516 | 172,738 | |
0.08197 % | Royce Investment Partners | 304,231 | 304,231 | |
0.07913 % | Alpine Global Management, LLC | 293,706 | 293,706 | |
0.07754 % | Legal & General Investment Management Ltd. | 287,796 | 95,029 | |
0.07394 % | TD Cowen (Research) | 274,420 | 0 | |
0.07329 % | Mellon Investments Corporation | 272,023 | 272,022 | |
0.07266 % | Jog (Vikram) | 269,683 | 45,718 | |
0.06943 % | BofA Global Research (US) | 257,680 | -378,659 | |
0.06809 % | BlackRock Investment Management (UK) Ltd. | 252,701 | 36,713 | |
0.06646 % | Davis (Jeremy Steven) | 246,666 | 50,833 | |
0.06637 % | California State Teachers Retirement System | 246,336 | 51,211 | |
0.06554 % | AQR Capital Management, LLC | 243,237 | 179,817 | |
0.06524 % | Jane Street Capital, L.L.C. | 242,154 | -1,141,543 | |
0.06372 % | Driehaus Capital Management, LLC | 236,479 | 0 | |
0.06034 % | Bradley & Co. Private Wealth Management, LLC | 223,939 | -223,938 | |
0.06008 % | Susquehanna International Group, LLP | 222,991 | -1,872,100 | |
0.04730 % | UBS Financial Services, Inc. | 175,536 | -308,408 | |
0.04447 % | T. Rowe Price International Ltd | 165,043 | 96,174 | |
0.04445 % | Commonwealth Financial Network | 164,993 | 8,802 | |
0.04373 % | Corebridge Financial Inc | 162,312 | 162,312 | |
0.04373 % | SunAmerica Asset Management, LLC | 162,312 | 0 | |
0.04351 % | Mirae Asset Global Investments (USA) LLC | 161,473 | -9,560 | |
0.04326 % | Rockefeller Capital Management | 160,556 | 890 | |
0.03785 % | Invesco Advisers, Inc. | 140,495 | 135,358 | |
0.03721 % | Cox (Troy M) | 138,093 | 43,128 | |
0.03671 % | BNP Paribas Securities Corp. North America | 136,237 | 118,477 | |
0.03644 % | Northern Trust Global Investments | 135,244 | -6,602 | |
0.03620 % | Goldman Sachs Asset Management, L.P. | 134,373 | 102,005 | |
0.03546 % | Janus Henderson Investors | 131,610 | 59,549 | |
0.03464 % | JPMorgan Private Bank (United States) | 128,576 | 128,576 | |
0.03358 % | Wells Fargo Bank, N.A. | 124,640 | 122,550 | |
0.03347 % | DWS Investments UK Limited | 124,226 | 120,027 | |
0.03290 % | Lauxera Capital Partners | 122,100 | 122,100 | |
0.03259 % | BlackRock Asset Management Ireland Limited | 120,964 | -786 | |
0.03163 % | Manulife Investment Management (North America) Limited | 117,395 | 110,907 | |
0.03037 % | Witney (Franklin R. Ph.D.) | 112,704 | 43,128 | |
0.02900 % | Wexford Capital LP | 107,619 | 107,619 | |
0.02776 % | Voya Investment Management LLC | 103,036 | 103,036 | |
0.02728 % | SG Americas Securities, L.L.C. | 101,257 | 52,970 | |
0.02710 % | RBF Capital, LLC | 100,572 | -341,000 | |
0.02694 % | Maven Investment Partners US Ltd. | 100,000 | 100,000 | |
0.02675 % | Metropolitan Life Insurance Co. (US) | 99,278 | 99,278 | |
0.02622 % | American Century Investment Management, Inc. | 97,307 | 70,924 | |
0.02374 % | Hightower Advisors, LLC | 88,101 | 12,000 | |
0.02199 % | Marshall Wace LLP | 81,617 | 0 | |
0.02129 % | New York State Common Retirement Fund | 79,000 | -43,200 | |