30.15166 % | OrbiMed Advisors, LLC | 16,589,442 | 5,680,186 | |
18.40026 % | Baker Bros. Advisors LP | 10,123,824 | 0 | |
7.51181 % | Deerfield Management Company, L.P. | 4,133,000 | 0 | |
4.93483 % | Vaddi (Krishna) | 2,715,145 | 0 | |
4.66792 % | Boxer Capital, L.L.C. | 2,568,287 | 0 | |
1.83672 % | The Vanguard Group, Inc. | 1,010,565 | -6,434 | |
1.62757 % | BlackRock Institutional Trust Company, N.A. | 895,487 | -32,050 | |
1.58934 % | T. Rowe Price Associates, Inc. | 874,455 | -50,673 | |
0.94943 % | MFS Investment Management | 522,375 | 14,226 | |
0.90894 % | Friedman (Paul A) | 500,098 | 0 | |
0.65785 % | Geode Capital Management, L.L.C. | 361,951 | 319 | |
0.58232 % | Sio Capital Management, LLC | 320,394 | 0 | |
0.56715 % | Combs (Andrew P) | 312,048 | 4,841 | |
0.44117 % | Morgan Stanley Smith Barney LLC | 242,729 | -2,224 | |
0.38485 % | State Street Global Advisors (US) | 211,746 | 305 | |
0.37550 % | Renaissance Technologies LLC | 206,600 | -38,200 | |
0.32840 % | Scherle (Peggy A) | 180,685 | 5,000 | |
0.29199 % | TD Asset Management Inc. | 160,652 | 0 | |
0.23270 % | Charles Schwab Investment Management, Inc. | 128,033 | 663 | |
0.22465 % | Bridgeway Capital Management, LLC | 123,600 | 0 | |
0.21063 % | Northern Trust Investments, Inc. | 115,888 | 2,539 | |
0.20600 % | BlackRock Financial Management, Inc. | 113,342 | -4,332 | |
0.17091 % | Two Sigma Investments, LP | 94,035 | -36,762 | |
0.13617 % | Goldman Sachs & Company, Inc. | 74,923 | 7,496 | |
0.12731 % | Manulife Investment Management (North America) Limited | 70,045 | -2,217 | |
0.11706 % | Exchange Traded Concepts, LLC | 64,409 | 15,682 | |
0.11512 % | Huang (Jane) | 63,341 | 6,026 | |
0.08288 % | Chardonnet (Laurent) | 45,599 | 3,434 | |
0.07731 % | Morgan Stanley & Co. LLC | 42,538 | -6,735 | |
0.07348 % | BlackRock Investment Management, LLC | 40,429 | 7,824 | |
0.06413 % | Kennedy Capital Management LLC | 35,283 | 10,248 | |
0.06230 % | BofA Global Research (US) | 34,278 | 2,014 | |
0.05705 % | Citadel Advisors LLC | 31,388 | 1,593 | |
0.05284 % | Dimensional Fund Advisors, L.P. | 29,074 | 14,769 | |
0.05089 % | LUNIS Verm¿gensmanagement AG | 28,000 | 0 | |
0.05077 % | BNY Mellon Asset Management | 27,934 | -1,589 | |
0.04622 % | Vident Investment Advisory, LLC | 25,428 | 25,428 | |
0.04527 % | HSBC Global Asset Management (UK) Limited | 24,905 | 0 | |
0.04019 % | Acadian Asset Management LLC | 22,110 | 0 | |
0.03919 % | Rhumbline Advisers Ltd. Partnership | 21,565 | 399 | |
0.03424 % | Y-Intercept (Hong Kong) Ltd | 18,839 | 18,839 | |
0.03399 % | State of Wisconsin Investment Board | 18,700 | -900 | |
0.03228 % | Jacobs Levy Equity Management, Inc. | 17,761 | 17,761 | |
0.03061 % | T. Rowe Price International Ltd | 16,843 | 0 | |
0.03053 % | Nuveen LLC | 16,797 | 0 | |
0.02792 % | BlackRock Investment Management (UK) Ltd. | 15,359 | 0 | |
0.02768 % | Walleye Capital LLC | 15,229 | -1,151 | |
0.02657 % | DWS Investments UK Limited | 14,618 | 14,618 | |
0.02654 % | Barclays Bank PLC | 14,601 | -5,786 | |
0.02353 % | Jane Street Capital, L.L.C. | 12,948 | -3,440 | |
0.02244 % | Connor, Clark & Lunn Investment Management Ltd. | 12,345 | -7,721 | |
0.02013 % | Prelude Capital Management, LLC | 11,074 | -2,772 | |
0.01987 % | UBS Financial Services, Inc. | 10,934 | -4,721 | |
0.01818 % | Dier (Mardi C) | 10,000 | 0 | |
0.01740 % | Fidelity Management & Research Company LLC | 9,575 | -1,975 | |
0.01663 % | American Century Investment Management, Inc. | 9,152 | 9,152 | |
0.01599 % | Northern Trust Global Investments | 8,798 | 0 | |
0.01516 % | Mellon Investments Corporation | 8,342 | -2,203 | |
0.01479 % | Mirae Asset Global Investments (USA) LLC | 8,135 | 8,134 | |
0.01419 % | Vaughan Nelson Investment Management, L.P. | 7,808 | 0 | |
0.01333 % | SunAmerica Asset Management, LLC | 7,333 | -64 | |
0.01289 % | Corebridge Financial Inc | 7,092 | 7,092 | |
0.01284 % | Tower Research Capital LLC | 7,064 | 3,717 | |
0.01113 % | Dimensional Fund Advisors, Ltd. | 6,124 | 0 | |
0.01053 % | Wells Fargo Bank, N.A. | 5,792 | 518 | |
0.01021 % | JPMorgan Private Bank (United States) | 5,618 | -387 | |
0.00781 % | BlackRock Japan Co., Ltd. | 4,299 | 0 | |
0.00658 % | New York State Common Retirement Fund | 3,622 | -15,500 | |
0.00580 % | AllianceBernstein L.P. | 3,190 | 0 | |
0.00568 % | Qube Research & Technologies Ltd | 3,126 | 3,126 | |
0.00548 % | Citi Investment Research (US) | 3,014 | 205 | |
0.00504 % | Horizon Kinetics LLC | 2,772 | 0 | |
0.00496 % | Goldman Sachs Asset Management, L.P. | 2,731 | 2,731 | |
0.00442 % | ProShare Advisors LLC | 2,434 | -102 | |
0.00436 % | Lim (Bryant David) | 2,400 | 0 | |
0.00329 % | Parametric Portfolio Associates LLC | 1,812 | 0 | |
0.00309 % | RBC Brewin Dolphin Ireland | 1,699 | 0 | |
0.00269 % | Russell Investments Trust Company | 1,481 | 1,481 | |
0.00233 % | BlackRock Fund Advisors | 1,281 | 1,281 | |
0.00225 % | RBC Wealth Management, International | 1,240 | 907 | |
0.00198 % | Mackenzie Investments | 1,088 | 0 | |
0.00175 % | Legal & General Investment Management Ltd. | 962 | 0 | |
0.00174 % | California State Teachers Retirement System | 955 | -541 | |
0.00169 % | Assenagon Asset Management S.A. | 931 | 233 | |
0.00168 % | Principal Global Investors (Equity) | 925 | -561 | |
0.00164 % | Blackstone Alternative Investment Advisors LLC | 900 | -300 | |
0.00149 % | Ameritas Investment Partners, Inc. | 819 | 0 | |
0.00079 % | Franklin Mutual Advisers, LLC | 436 | 0 | |
0.00061 % | Amalgamated Bank Institutional Asset Management & Custody | 334 | 0 | |
0.00051 % | ProFund Advisors LLC | 282 | -42 | |
0.00047 % | Guggenheim Investments | 258 | 0 | |
0.00044 % | J.P. Morgan Securities plc | 242 | 0 | |
0.00037 % | JGP Gest¿o de Recursos Ltda. | 204 | -10 | |
0.00028 % | Morgan Stanley & Co. International Plc | 153 | 108 | |
0.00023 % | L2 Asset Management, LLC | 125 | 0 | |
0.00022 % | Morgan Stanley Investment Management Inc. (US) | 122 | 0 | |
0.00012 % | PNC Investments LLC | 64 | 64 | |
0.00009 % | HighMark Wealth Management LLC | 50 | 0 | |
0.00003 % | SRS Capital Advisors, Inc | 19 | 19 | |
0.00002 % | Carson Wealth Management Group | 10 | -12 | |