10.62690 % | Fidelity Management & Research Company LLC | 16,023,239 | 1,455,424 | |
9.68647 % | MVM Partners LLP | 14,605,263 | 0 | |
9.10406 % | Great Point Partners, LLC | 13,727,097 | 4,940,779 | |
8.89955 % | Nantahala Capital Management, LLC | 13,418,740 | 10,944,444 | |
5.49642 % | Rosalind Advisors, Inc. | 8,287,503 | 740,355 | |
4.83486 % | Kruttschnitt (Theodore H III) | 7,290,000 | 474,211 | |
4.49586 % | Acorn Bioventures L.P. | 6,778,851 | 407,388 | |
3.71351 % | Kingdon Capital Management, L.L.C. | 5,599,237 | 1,700,000 | |
3.31609 % | D. E. Shaw & Co., L.P. | 5,000,000 | 5,000,000 | |
2.98448 % | BlackRock Financial Management, Inc. | 4,500,000 | 4,322,013 | |
2.68280 % | Bleichroeder LP | 4,045,132 | 0 | |
2.55627 % | The Vanguard Group, Inc. | 3,854,345 | -388,265 | |
1.93680 % | MFS Investment Management | 2,920,309 | 81,233 | |
1.65329 % | Velan Capital Investment Management LP | 2,492,830 | -508,361 | |
1.55857 % | Stonepine Capital Management, LLC | 2,350,010 | 2,350,010 | |
1.48974 % | Easterly Investment Partners LLC | 2,246,224 | 208,185 | |
0.75648 % | Rice Hall James & Associates, LLC | 1,140,626 | 152,435 | |
0.73664 % | GMT Capital Corp. | 1,110,702 | 1,110,702 | |
0.71338 % | Millennium Management LLC | 1,075,640 | 744,954 | |
0.64426 % | Geode Capital Management, L.L.C. | 971,415 | -599,245 | |
0.63523 % | Miller (Peter K) | 957,797 | 170,382 | |
0.51934 % | Prescott Group Capital Management, LLC | 783,065 | -56,502 | |
0.50385 % | BlackRock Institutional Trust Company, N.A. | 759,698 | -3,174,305 | |
0.39157 % | Northern Trust Investments, Inc. | 590,403 | 17,740 | |
0.24902 % | Jane Street Capital, L.L.C. | 375,471 | 375,471 | |
0.23876 % | Prelude Capital Management, LLC | 360,000 | 0 | |
0.23678 % | Mahmoud (Ramy A) | 357,023 | -4,881 | |
0.19817 % | State Street Global Advisors (US) | 298,803 | -1,064,129 | |
0.18376 % | Goldman Sachs & Company, Inc. | 277,069 | 204,150 | |
0.15469 % | Susquehanna International Group, LLP | 233,235 | 233,235 | |
0.15460 % | Renaissance Technologies LLC | 233,100 | -48,800 | |
0.14465 % | Bridgeway Capital Management, LLC | 218,100 | -120,000 | |
0.13671 % | UBS Asset Management (Americas), Inc. | 206,134 | 0 | |
0.11381 % | Squarepoint Capital LLP | 171,610 | 108,903 | |
0.10883 % | Newton Investment Management North America, LLC | 164,100 | 0 | |
0.10672 % | Verition Fund Management LLC | 160,908 | 160,908 | |
0.09948 % | Kohler (Terry) | 150,000 | 150,000 | |
0.09852 % | Qube Research & Technologies Ltd | 148,551 | 148,551 | |
0.09054 % | Krick (Anthony J) | 136,519 | -6,845 | |
0.08701 % | Centiva Capital, LP | 131,200 | 131,200 | |
0.07856 % | Marino (Michael F III) | 118,460 | -3,226 | |
0.06632 % | Brown Brothers Harriman & Company | 100,000 | 0 | |
0.05624 % | Y-Intercept (Hong Kong) Ltd | 84,806 | 84,806 | |
0.05604 % | XTX Markets LLC | 84,504 | 84,504 | |
0.05514 % | Paloma Partners Management Company | 83,141 | 83,141 | |
0.05424 % | Alpine Global Management, LLC | 81,782 | 81,782 | |
0.05198 % | Palumbo Wealth Management LLC | 78,378 | -57,153 | |
0.04978 % | Morgan Stanley Smith Barney LLC | 75,061 | 7,525 | |
0.04724 % | Barclays Bank PLC | 71,230 | -29,557 | |
0.04586 % | HRT Financial LP | 69,146 | 69,146 | |
0.03166 % | Northern Trust Global Investments | 47,730 | 0 | |
0.03164 % | Morgan Stanley & Co. LLC | 47,709 | -52,428 | |
0.02958 % | PGIM Quantitative Solutions LLC | 44,600 | 8,160 | |
0.02590 % | Citadel Advisors LLC | 39,048 | -64,425 | |
0.02482 % | Mirae Asset Global Investments (USA) LLC | 37,421 | 37,420 | |
0.02399 % | Charles Schwab Investment Management, Inc. | 36,174 | -166,635 | |
0.02392 % | Invesco Capital Management LLC | 36,074 | 34,810 | |
0.02383 % | SunAmerica Asset Management, LLC | 35,933 | -310 | |
0.02140 % | Citi Investment Research (US) | 32,273 | 22,105 | |
0.02053 % | Goldman Sachs Asset Management, L.P. | 30,951 | -21,168 | |
0.02005 % | Hightower Advisors, LLC | 30,235 | 0 | |
0.01988 % | HSBC Global Asset Management (UK) Limited | 29,979 | -306 | |
0.01887 % | FreeGulliver LLC | 28,450 | 18,000 | |
0.01758 % | Schonfeld Strategic Advisors LLC | 26,500 | 26,500 | |
0.01658 % | HighMark Wealth Management LLC | 25,000 | 0 | |
0.01563 % | Tower Research Capital LLC | 23,574 | 18,109 | |
0.01373 % | Engineers Gate Manager, L.P. | 20,695 | 20,695 | |
0.01233 % | BNY Mellon Asset Management | 18,584 | -133,796 | |
0.01004 % | BofA Global Research (US) | 15,138 | 4,392 | |
0.00964 % | Victory Capital Management Inc. | 14,533 | 3,994 | |
0.00956 % | BlackRock Investment Management, LLC | 14,416 | -156,866 | |
0.00826 % | Jump Financial, LLC | 12,449 | 12,449 | |
0.00819 % | Legato Capital Management LLC | 12,356 | 2 | |
0.00809 % | Mariner Wealth Advisors | 12,203 | -474 | |
0.00798 % | Tradition Wealth Management, LLC | 12,037 | 12,037 | |
0.00693 % | Virtu Americas LLC | 10,456 | 10,456 | |
0.00663 % | Arete Wealth Advisors, LLC | 10,000 | 10,000 | |
0.00663 % | Truist Bank | 10,000 | 10,000 | |
0.00600 % | Rhumbline Advisers Ltd. Partnership | 9,054 | -85,031 | |
0.00533 % | Mackenzie Investments | 8,036 | -8 | |
0.00530 % | Parametric Portfolio Associates LLC | 7,984 | -5,636 | |
0.00343 % | Russell Investments Trust Company | 5,171 | 190 | |
0.00337 % | J.P. Morgan Securities LLC | 5,078 | -88,737 | |
0.00315 % | T. Rowe Price Associates, Inc. | 4,747 | 0 | |
0.00267 % | Metropolitan Life Insurance Co. (US) | 4,030 | 4,030 | |
0.00243 % | Macquarie Investment Management Global Ltd. | 3,671 | 3,671 | |
0.00199 % | Adar1 Capital Management LLC | 3,000 | 3,000 | |
0.00194 % | Morgan Stanley & Co. International Plc | 2,921 | 2,579 | |
0.00126 % | BNP Paribas Securities Corp. North America | 1,907 | -176,606 | |
0.00115 % | J.P. Morgan Securities plc | 1,734 | 0 | |
0.00106 % | UBS Financial Services, Inc. | 1,598 | -71,643 | |
0.00099 % | National Bank of Canada | 1,500 | 0 | |
0.00075 % | JP Morgan Asset Management | 1,133 | -2,073 | |
0.00065 % | ProFund Advisors LLC | 981 | -613 | |
0.00041 % | Morgan Stanley Investment Management Inc. (US) | 615 | 76 | |
0.00031 % | Wells Fargo Advisors | 465 | 215 | |
0.00011 % | SRS Capital Advisors, Inc | 168 | 168 | |
0.00007 % | RBC Dominion Securities, Inc. | 100 | -3,000 | |
0.00002 % | RBC Capital Markets Wealth Management | 33 | 0 | |
0.00001 % | Farther Finance Advisors, LLC | 8 | 0 | |