9.74559 % | Vestal Point Capital, LP | 4,750,000 | 25,000 | |
5.43798 % | Nantahala Capital Management, LLC | 2,650,472 | -437,610 | |
4.56504 % | Boxer Capital, L.L.C. | 2,225,000 | -275,000 | |
3.95786 % | abrdn Inc. | 1,929,061 | 1,528,581 | |
3.89824 % | 683 Capital Management LLC | 1,900,000 | -75,000 | |
3.57069 % | Schroder Investment Management Ltd. (SIM) | 1,740,354 | 498,854 | |
3.10214 % | BlackRock Institutional Trust Company, N.A. | 1,511,983 | 37,414 | |
2.54719 % | International Biotechnology Trust PLC | 1,241,500 | 1,226,000 | |
2.50857 % | Adar1 Capital Management LLC | 1,222,676 | 929,826 | |
2.38311 % | The Vanguard Group, Inc. | 1,161,528 | 88,992 | |
2.05381 % | Morgan Stanley & Co. LLC | 1,001,027 | 58,486 | |
1.74614 % | Columbia Threadneedle Investments (US) | 851,070 | 141,635 | |
1.66007 % | Hudson Bay Capital Management LP | 809,117 | 284,117 | |
1.65984 % | Citadel Advisors LLC | 809,008 | 258,441 | |
1.44884 % | Macquarie Investment Management | 706,166 | 0 | |
1.31394 % | Privium Fund Management BV | 640,416 | 61,501 | |
1.22886 % | BNP Paribas Securities Corp. North America | 598,945 | -137,779 | |
1.18180 % | D. E. Shaw & Co., L.P. | 576,008 | -274,092 | |
1.08391 % | Franklin Advisers, Inc. | 528,300 | 528,300 | |
1.06774 % | Verition Fund Management LLC | 520,416 | 209,849 | |
1.05708 % | Millennium Management LLC | 515,221 | 40,642 | |
1.05405 % | Acadian Asset Management LLC | 513,746 | -99,744 | |
1.03045 % | Geode Capital Management, L.L.C. | 502,240 | 2,420 | |
0.96600 % | JPMorgan Asset Management U.K. Limited | 470,830 | -90,263 | |
0.94378 % | LifeSci Fund Management LLC | 460,000 | 0 | |
0.86313 % | DWS Investments UK Limited | 420,689 | 420,689 | |
0.74343 % | Bridger Management, LLC | 362,349 | 0 | |
0.68522 % | Two Sigma Investments, LP | 333,976 | -191,801 | |
0.66991 % | Jane Street Capital, L.L.C. | 326,516 | 110,847 | |
0.66813 % | Kapusta Matthew C | 325,647 | 100,794 | |
0.62259 % | Goldman Sachs & Company, Inc. | 303,450 | -58,883 | |
0.56327 % | PFM Health Sciences, LP | 274,540 | 0 | |
0.55672 % | Assenagon Asset Management S.A. | 271,346 | 89,400 | |
0.54365 % | BofA Global Research (US) | 264,974 | -49,483 | |
0.53511 % | Charles Schwab Investment Management, Inc. | 260,811 | 25,321 | |
0.51697 % | Susquehanna International Group, LLP | 251,969 | -251,914 | |
0.45959 % | Point72 Asset Management, L.P. | 224,004 | 38,780 | |
0.44982 % | Group One Trading, L.P. | 219,243 | -34,784 | |
0.44604 % | Carlson Capital, L.P. | 217,400 | -10,000 | |
0.43953 % | Schonfeld Strategic Advisors LLC | 214,226 | 198,326 | |
0.42491 % | Norges Bank Investment Management (NBIM) | 207,100 | 0 | |
0.42271 % | J. Goldman & Co., L.P. | 206,028 | -304,477 | |
0.38872 % | J.P. Morgan Securities LLC | 189,463 | -208,885 | |
0.37123 % | UBS O'Connor LLC | 180,939 | 109,875 | |
0.35885 % | State Street Global Advisors (US) | 174,902 | -1,400 | |
0.35674 % | BlackRock Investment Management (UK) Ltd. | 173,876 | 0 | |
0.34617 % | BlackRock Financial Management, Inc. | 168,723 | 14,610 | |
0.28519 % | PDT Partners, LLC | 139,001 | 17,136 | |
0.26265 % | Boothbay Fund Management, LLC | 128,014 | -64,800 | |
0.23646 % | Abi-Saab (Walid) | 115,253 | -1,447 | |
0.22721 % | Invesco Capital Management LLC | 110,741 | 2,143 | |
0.20457 % | Sigma Planning Corporation | 99,705 | 17,050 | |
0.18839 % | Potts (Jeannette) | 91,819 | -4,781 | |
0.18836 % | Northern Trust Investments, Inc. | 91,808 | 7,399 | |
0.18069 % | Parametric Portfolio Associates LLC | 88,067 | 80,415 | |
0.17282 % | Mirae Asset Global Investments (USA) LLC | 84,233 | -73,079 | |
0.16271 % | SELECTRA Management Company S.A. | 79,306 | 0 | |
0.15790 % | RBC Capital Markets Wealth Management | 76,960 | 23,425 | |
0.15722 % | Diamond Hill Capital Management Inc. | 76,630 | 0 | |
0.15391 % | Jump Financial, LLC | 75,017 | -24,659 | |
0.14909 % | Klemt (Christian) | 72,666 | -1,611 | |
0.14301 % | Shay Capital LLC | 69,702 | 4,876 | |
0.13966 % | Sanders Morris LLC | 68,070 | 0 | |
0.13936 % | BlackRock Advisors (UK) Limited | 67,924 | 51 | |
0.13890 % | American Century Investment Management, Inc. | 67,699 | 8,642 | |
0.13875 % | BlackRock Asset Management Ireland Limited | 67,629 | 15,953 | |
0.13459 % | Pale Fire Capital SE | 65,600 | 0 | |
0.12934 % | Stifel, Nicolaus & Company, Incorporated | 63,040 | 39,525 | |
0.12310 % | Moore Capital Management, LP | 60,000 | 0 | |
0.10538 % | Bellecapital AG | 51,363 | 0 | |
0.10259 % | Sonic GP LLC | 50,000 | 0 | |
0.10153 % | Citi Investment Research (US) | 49,485 | 9,496 | |
0.09951 % | Pennant Investors, LP | 48,500 | 0 | |
0.09904 % | Covestor, Ltd. | 48,273 | -5,417 | |
0.09754 % | Avantis Investors | 47,540 | 14,561 | |
0.09473 % | Balyasny Asset Management LP | 46,169 | 17,379 | |
0.08750 % | Dolmetsch (Ricardo) | 42,648 | -5,080 | |
0.08704 % | Gut (Robert) | 42,425 | 4,576 | |
0.08474 % | Erste Asset Management GmbH | 41,300 | 0 | |
0.08059 % | Algert Global LLC | 39,281 | 39,281 | |
0.08018 % | Marshall Wace LLP | 39,078 | 39,078 | |
0.06937 % | Caloz (Pierre Alain) | 33,811 | 3,355 | |
0.06879 % | Point72 Asia (Singapore) Pte. Ltd. | 33,530 | 1,487 | |
0.06815 % | Porter (Richard Ph.D.) | 33,216 | 33,216 | |
0.06712 % | DNB Asset Management AS | 32,712 | 8,035 | |
0.06571 % | Trexquant Investment LP | 32,026 | 32,026 | |
0.06368 % | Fubon Asset Management Company Ltd. | 31,037 | -856 | |
0.05571 % | Morgan Stanley Smith Barney LLC | 27,154 | 11,434 | |
0.05231 % | Cubist Systematic Strategies, LLC | 25,494 | 14,454 | |
0.04828 % | Ballentine Partners, LLC | 23,534 | 23,534 | |
0.04817 % | Tudor Investment Corporation | 23,479 | -174 | |
0.04780 % | T. Rowe Price International Ltd | 23,300 | 7,200 | |
0.04747 % | Balachandran (Madhavan) | 23,139 | 5,849 | |
0.04747 % | Springhorn (Jeremy P) | 23,136 | 5,849 | |
0.04674 % | Wolverine Trading, LLC | 22,780 | 22,780 | |
0.04614 % | Jacques (Rachelle Suzanne) | 22,488 | 5,859 | |
0.04279 % | Graham Capital Management, L.P. | 20,858 | 20,858 | |
0.04001 % | Clear Harbor Asset Management, LLC | 19,500 | -28,500 | |
0.03700 % | Meek (David D) | 18,032 | 5,851 | |
0.03671 % | Dynamic Technology Lab Pte. Ltd. | 17,894 | 17,894 | |