13.66144 % | Fidelity Management & Research Company LLC | 21,520,872 | 21,950 | |
8.99929 % | The Vanguard Group, Inc. | 14,176,576 | -298,544 | |
8.38028 % | T. Rowe Price Investment Management, Inc. | 13,201,453 | 78,398 | |
5.53164 % | Bellevue Asset Management AG | 8,713,987 | -519,713 | |
4.61203 % | BlackRock Institutional Trust Company, N.A. | 7,265,336 | 85,070 | |
2.98831 % | ClearBridge Investments, LLC | 4,707,480 | -133,215 | |
2.93086 % | Wellington Management Company, LLP | 4,616,978 | 2,856,353 | |
2.60465 % | T. Rowe Price Associates, Inc. | 4,103,111 | 489,089 | |
2.54478 % | State Street Global Advisors (US) | 4,008,797 | 53,768 | |
2.23343 % | Pictet Asset Management Ltd. | 3,518,317 | 277,383 | |
2.19303 % | Tweedy, Browne Company LLC | 3,454,676 | -55,497 | |
1.96041 % | Macquarie Investment Management | 3,088,235 | 152,311 | |
1.54168 % | BVF Partners L.P. | 2,428,613 | -1,576,000 | |
1.44476 % | Geode Capital Management, L.L.C. | 2,275,931 | 81,200 | |
1.31073 % | OrbiMed Advisors, LLC | 2,064,797 | -104,703 | |
1.01178 % | Two Sigma Investments, LP | 1,593,863 | 508,151 | |
0.98713 % | Farallon Capital Management, L.L.C. | 1,555,020 | 828,020 | |
0.88863 % | ARK Investment Management LLC | 1,399,852 | -505,204 | |
0.87939 % | Adage Capital Management, L.P. | 1,385,300 | 318,300 | |
0.80957 % | Charles Schwab Investment Management, Inc. | 1,275,319 | 33,012 | |
0.79291 % | Deep Track Capital LP | 1,249,068 | -1,585,001 | |
0.74394 % | Norges Bank Investment Management (NBIM) | 1,171,936 | -124,711 | |
0.69684 % | First Trust Advisors L.P. | 1,097,730 | -37,249 | |
0.62133 % | Point72 Asset Management, L.P. | 978,783 | 818,970 | |
0.61435 % | BlackRock Financial Management, Inc. | 967,782 | -114,119 | |
0.60741 % | TD Asset Management Inc. | 956,852 | 58,000 | |
0.56905 % | Candriam Luxembourg S.A. | 896,429 | 0 | |
0.56518 % | Millennium Management LLC | 890,325 | 453,202 | |
0.54910 % | Camber Capital Management LP | 865,000 | -1,385,000 | |
0.53289 % | Capital World Investors | 839,463 | 0 | |
0.53289 % | Capital Research Global Investors | 839,463 | 0 | |
0.50332 % | Pictet Asset Management (Japan) Ltd. | 792,877 | 244,788 | |
0.42171 % | Medical Strategy GmbH | 664,313 | -5,500 | |
0.39933 % | Candriam Belgium S.A. | 629,067 | 80,000 | |
0.39830 % | Jacobs Levy Equity Management, Inc. | 627,444 | 174,368 | |
0.39166 % | Barclays Bank PLC | 616,978 | 10,324 | |
0.36917 % | Northern Trust Investments, Inc. | 581,552 | 27,095 | |
0.33792 % | Wells Fargo Advisors | 532,322 | 232 | |
0.33666 % | RBC Wealth Management, International | 530,347 | 59,776 | |
0.31054 % | Nomura Securities Co., Ltd. | 489,189 | 29,878 | |
0.31038 % | BlackRock Asset Management Ireland Limited | 488,948 | -11,615 | |
0.30669 % | JPMorgan Asset Management U.K. Limited | 483,123 | -104,818 | |
0.29502 % | AXA Investment Managers UK Ltd. | 464,741 | -16,841 | |
0.29136 % | Pinnacle Associates Ltd. | 458,979 | -4,056 | |
0.26942 % | Morgan Stanley & Co. LLC | 424,417 | 63,465 | |
0.23474 % | J.P. Morgan Securities LLC | 369,779 | 159,449 | |
0.22665 % | Groupama Asset Management | 357,036 | 45,285 | |
0.22642 % | First Turn Management, LLC | 356,679 | 356,679 | |
0.22533 % | BNP Paribas Securities Corp. North America | 354,955 | -55,719 | |
0.21562 % | BNP Paribas Asset Management USA, Inc. | 339,667 | 339,667 | |
0.20609 % | Eversept Partners, LP | 324,654 | 72,208 | |
0.20568 % | Nuveen LLC | 324,006 | 20,000 | |
0.20564 % | Morgan Stanley Smith Barney LLC | 323,938 | 29,512 | |
0.19887 % | Schonfeld Strategic Advisors LLC | 313,274 | 251,726 | |
0.19283 % | Managed Account Advisors LLC | 303,762 | -35,531 | |
0.19044 % | C WorldWide Asset Management Fondsmaeglerselskab A/S | 300,000 | 300,000 | |
0.18948 % | Baillie Gifford & Co. | 298,483 | -18,146 | |
0.18605 % | Nikko Asset Management Americas, Inc. | 293,078 | -242,144 | |
0.18027 % | Liontrust Investment Partners LLP | 283,981 | -26,045 | |
0.16969 % | Corient Private Wealth LLC | 267,312 | -39,678 | |
0.16766 % | Voloridge Investment Management, LLC | 264,121 | 264,121 | |
0.16694 % | BNY Mellon Asset Management | 262,981 | 7,599 | |
0.16549 % | Manulife Investment Management (North America) Limited | 260,702 | 31,025 | |
0.16335 % | AllianceBernstein L.P. | 257,320 | -47,198 | |
0.16305 % | Mellon Investments Corporation | 256,852 | 1,239 | |
0.16143 % | Schweizerische Nationalbank | 254,300 | -28,800 | |
0.16030 % | Citadel Advisors LLC | 252,528 | -283,390 | |
0.15938 % | Parametric Portfolio Associates LLC | 251,070 | -27,900 | |
0.15541 % | Stifel, Nicolaus & Company, Incorporated | 244,818 | -181 | |
0.14500 % | Kennedy Capital Management LLC | 228,425 | -10,210 | |
0.13982 % | Nikko Asset Management Co., Ltd. | 220,261 | -32,198 | |
0.13806 % | Privium Fund Management BV | 217,493 | -11,000 | |
0.13744 % | BMO Capital Markets (US) | 216,517 | -3,173 | |
0.13621 % | Goldman Sachs & Company, Inc. | 214,564 | 37,366 | |
0.13420 % | Parkman Healthcare Partners LLC | 211,400 | 51,897 | |
0.13295 % | California Public Employees' Retirement System | 209,436 | -445,935 | |
0.13277 % | Altrinsic Global Advisors, LLC | 209,152 | -83,032 | |
0.12930 % | Delaware Advisors, LLC | 203,682 | 23,279 | |
0.12847 % | AXA Investment Managers Paris | 202,374 | 0 | |
0.12842 % | Jefferies LLC | 202,300 | 42,090 | |
0.12719 % | RBC Capital Markets Wealth Management | 200,368 | 11,362 | |
0.12696 % | Tang Capital Management, LLC | 200,000 | 0 | |
0.12663 % | Cubist Systematic Strategies, LLC | 199,477 | 199,477 | |
0.12659 % | Rhumbline Advisers Ltd. Partnership | 199,416 | 1,956 | |
0.12334 % | Sicart Associates LLC | 194,293 | -8,839 | |
0.12037 % | Superstring Capital Management LP | 189,618 | 189,618 | |
0.11706 % | Assenagon Asset Management S.A. | 184,401 | 184,401 | |
0.11705 % | Rafferty Asset Management LLC | 184,396 | -31,575 | |
0.11660 % | Raymond James & Associates, Inc. | 183,676 | -10,953 | |
0.11064 % | Monia (Brett P) | 174,289 | 22,438 | |
0.10892 % | Credit Suisse Funds AG | 171,587 | 7,950 | |
0.10771 % | Susquehanna Portfolio Strategies, LLC | 169,678 | 169,678 | |
0.10173 % | Goldman Sachs Asset Management, L.P. | 160,249 | 5,253 | |
0.10143 % | Tocqueville Asset Management LP | 159,780 | -1,950 | |
0.10140 % | UBS Financial Services, Inc. | 159,739 | 50,705 | |
0.09861 % | Legal & General Investment Management Ltd. | 155,348 | -9,687 | |
0.09786 % | Jane Street Capital, L.L.C. | 154,164 | -99,327 | |
0.09647 % | T. Rowe Price International Ltd | 151,963 | 7,988 | |
0.09589 % | Florida State Board of Administration | 151,055 | 67 | |
0.09480 % | Sonora Investment Management Group, LLC | 149,338 | 888 | |