8.44775 % | RTW Investments L.P. | 3,557,347 | 300,000 | |
7.83662 % | Adage Capital Management, L.P. | 3,300,000 | 2,000,000 | |
7.32232 % | RA Capital Management, LP | 3,083,430 | 0 | |
6.90159 % | Great Point Partners, LLC | 2,906,259 | 285,714 | |
5.81638 % | Point72 Asset Management, L.P. | 2,449,277 | 1,337,257 | |
5.46908 % | Menora Mivtachim Insurance Ltd. | 2,303,031 | 0 | |
4.98571 % | TD Cowen (Research) | 2,099,482 | 472,893 | |
4.54209 % | BlackRock Institutional Trust Company, N.A. | 1,912,673 | 376,291 | |
3.91831 % | Cormorant Asset Management, LP | 1,650,000 | 1,650,000 | |
3.73386 % | Monograph Capital Partners I LP | 1,572,327 | 1,572,327 | |
3.25778 % | Morgan Stanley & Co. LLC | 1,371,853 | 1,175,176 | |
3.25176 % | Arkin Communication, Ltd. | 1,369,315 | 0 | |
3.13465 % | UBS Asset Management (UK) Ltd. | 1,320,000 | 1,320,000 | |
2.75682 % | Millennium Management LLC | 1,160,899 | 1,119,019 | |
2.61696 % | SilverArc Capital Management, LLC | 1,102,000 | 593,413 | |
2.29162 % | Jefferies LLC | 965,000 | 125,000 | |
1.88911 % | Medical Strategy GmbH | 795,503 | -34,437 | |
1.72566 % | State Street Global Advisors (US) | 726,676 | 189,682 | |
1.63019 % | Migdal Insurance and Financial Holdings Ltd | 686,472 | 0 | |
1.17693 % | Wildcat Capital Management, LLC | 495,606 | 0 | |
1.11375 % | Dafna Capital Management, LLC | 469,000 | 469,000 | |
1.10014 % | Harel Insurance Investments and Financial Services Ltd | 463,267 | -298 | |
1.07275 % | Morgan Stanley Investment Management Inc. (US) | 451,737 | 270,978 | |
1.00069 % | Geode Capital Management, L.L.C. | 421,389 | 97,437 | |
0.97839 % | Opaleye Management Inc. | 412,000 | 142,000 | |
0.97054 % | Belldegrun (Arie S) | 408,693 | 0 | |
0.77640 % | Barrett (Elizabeth A) | 326,941 | 0 | |
0.72130 % | Woodline Partners LP | 303,740 | 303,740 | |
0.65178 % | Parkman Healthcare Partners LLC | 274,465 | 90,281 | |
0.64568 % | Rice Hall James & Associates, LLC | 271,897 | 199,110 | |
0.58988 % | Schonfeld Strategic Advisors LLC | 248,399 | 144,299 | |
0.57914 % | Goldman Sachs & Company, Inc. | 243,875 | 147,206 | |
0.53190 % | The Vanguard Group, Inc. | 223,982 | 29,016 | |
0.48425 % | Wells Fargo Advisors | 203,917 | -14 | |
0.43226 % | Northern Trust Investments, Inc. | 182,025 | -11,882 | |
0.41312 % | Balyasny Asset Management LP | 173,966 | 148,995 | |
0.38138 % | Laurion Capital Management LP | 160,600 | -90,000 | |
0.37064 % | Wellington Management Company, LLP | 156,078 | 19,337 | |
0.36044 % | ARK Investment Management LLC | 151,781 | 5,452 | |
0.34381 % | Atom Investors LP | 144,780 | 94,990 | |
0.33304 % | Schoenberg (Mark) | 140,244 | 807 | |
0.29761 % | Two Sigma Investments, LP | 125,322 | 26,025 | |
0.24516 % | BlackRock Financial Management, Inc. | 103,238 | 20,717 | |
0.23747 % | Alyeska Investment Group, L.P. | 100,000 | 100,000 | |
0.22879 % | Susquehanna International Group, LLP | 96,345 | 68,934 | |
0.22443 % | BlackRock Investment Management, LLC | 94,507 | 33,903 | |
0.21656 % | Nuveen LLC | 91,194 | 9,538 | |
0.19691 % | Charles Schwab Investment Management, Inc. | 82,917 | 20,037 | |
0.19356 % | De Lisle Partners LLP | 81,510 | 4,417 | |
0.19166 % | Trexquant Investment LP | 80,709 | 80,709 | |
0.18308 % | Valu-Trac Investment Management Ltd. | 77,093 | -1,234 | |
0.18238 % | Oak Ridge Investments, LLC | 76,799 | -3,130 | |
0.17942 % | Annandale Capital, LLC | 75,552 | -6,000 | |
0.17668 % | WesBanco Bank, Inc. | 74,400 | 47,000 | |
0.17659 % | Citadel Advisors LLC | 74,362 | 2,546 | |
0.17223 % | BNY Mellon Asset Management | 72,528 | 16,516 | |
0.16896 % | BlackRock Advisors (UK) Limited | 71,150 | 3,369 | |
0.16374 % | BlackRock Asset Management Ireland Limited | 68,952 | 51,717 | |
0.15694 % | BofA Global Research (US) | 66,086 | 13,023 | |
0.14323 % | Jane Street Capital, L.L.C. | 60,316 | 37,899 | |
0.13681 % | Walleye Capital LLC | 57,610 | 57,610 | |
0.11987 % | Rhumbline Advisers Ltd. Partnership | 50,477 | 13,681 | |
0.10704 % | Columbia Threadneedle Investments (US) | 45,075 | -25,877 | |
0.10674 % | Cubist Systematic Strategies, LLC | 44,949 | 38,799 | |
0.10174 % | Marshall Wace LLP | 42,841 | 42,841 | |
0.09618 % | Monashee Investment Management, LLC | 40,500 | 40,500 | |
0.09143 % | Coastal Bridge Advisors, LLC | 38,500 | 1,500 | |
0.08582 % | Meitav Dash Investments Ltd. | 36,138 | -660 | |
0.08129 % | AllianceBernstein L.P. | 34,230 | 22,280 | |
0.08109 % | Alps Advisors, Inc. | 34,149 | 5,860 | |
0.07654 % | Northern Trust Global Investments | 32,230 | -3,060 | |
0.07496 % | Tidal Investments LLC | 31,565 | 3,245 | |
0.07193 % | AQR Capital Management, LLC | 30,290 | -11,972 | |
0.05991 % | Smith (Jason Drew) | 25,226 | 1,812 | |
0.05823 % | Apo Asset Management GmbH | 24,519 | 0 | |
0.05818 % | Palo Alto Investors LP | 24,500 | 0 | |
0.05721 % | Mellon Investments Corporation | 24,091 | 11,884 | |
0.05699 % | Main Street Financial Solutions, LLC | 24,000 | 24,000 | |
0.05182 % | Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet LTD | 21,823 | 0 | |
0.04849 % | Kim (Dong) | 20,419 | 2,500 | |
0.04779 % | Vivaldi Capital Management, LP | 20,124 | 0 | |
0.04759 % | MetLife Investment Management, LLC | 20,039 | 5,413 | |
0.04686 % | Goldman Sachs Asset Management, L.P. | 19,731 | 2,538 | |
0.04589 % | Oppenheimer Asset Management Inc. | 19,323 | 19,323 | |
0.04389 % | Corebridge Financial Inc | 18,481 | 18,481 | |
0.04037 % | ACCI Capital Investments SGIIC, SA | 17,000 | 0 | |
0.03977 % | Assenagon Asset Management S.A. | 16,748 | 1,963 | |
0.03970 % | Cresset Asset Management, LLC | 16,716 | -133 | |
0.03734 % | Mirae Asset Global Investments (USA) LLC | 15,722 | 15,722 | |
0.03653 % | Partners Capital Investment Group, LLP | 15,384 | 15,384 | |
0.03562 % | Cohen (Frederick E) | 15,000 | 0 | |
0.03477 % | JPMorgan Private Bank (United States) | 14,640 | 3,975 | |
0.03395 % | Aperio Group, LLC | 14,296 | -5,742 | |
0.03339 % | SG Americas Securities, L.L.C. | 14,062 | 14,062 | |
0.03245 % | SunAmerica Asset Management, LLC | 13,664 | 143 | |
0.03235 % | DWS Investments UK Limited | 13,621 | 1,916 | |
0.03159 % | Manulife Investment Management (North America) Limited | 13,302 | -19,219 | |
0.03027 % | Engineers Gate Manager, L.P. | 12,745 | 109 | |
0.02832 % | Wells Fargo Bank, N.A. | 11,924 | 3,575 | |
0.02823 % | ProShare Advisors LLC | 11,888 | 5,385 | |