21.78965 % | Nippon Shinyaku Co Ltd | 7,090,351 | 4,944,429 | |
4.76011 % | The Vanguard Group, Inc. | 1,548,941 | 183,038 | |
4.60014 % | BlackRock Institutional Trust Company, N.A. | 1,496,887 | 1,118,747 | |
1.97164 % | Geode Capital Management, L.L.C. | 641,573 | 313,096 | |
1.47360 % | Millennium Management LLC | 479,510 | 186,469 | |
1.23240 % | State Street Global Advisors (US) | 401,022 | 284,298 | |
0.61317 % | Marban (Linda) | 199,524 | -177,855 | |
0.49877 % | Osaic Holdings, Inc. | 162,300 | 4,100 | |
0.42256 % | Renaissance Technologies LLC | 137,500 | 84,350 | |
0.40955 % | Litvack (Frank) | 133,269 | 0 | |
0.34284 % | Northern Trust Investments, Inc. | 111,561 | 13,492 | |
0.27447 % | Marshall Wace LLP | 89,314 | 89,314 | |
0.27286 % | Musket (David B) | 88,788 | 34,000 | |
0.26015 % | AHL Partners LLP | 84,654 | 11,757 | |
0.22578 % | Charles Schwab Investment Management, Inc. | 73,468 | 59,989 | |
0.21858 % | BlackRock Investment Management, LLC | 71,127 | 67,532 | |
0.20680 % | Goldman Sachs & Company, Inc. | 67,294 | -130,635 | |
0.20564 % | Citadel Advisors LLC | 66,914 | 36,111 | |
0.18754 % | BNY Mellon Asset Management | 61,025 | 50,724 | |
0.18604 % | BlackRock Financial Management, Inc. | 60,536 | 60,536 | |
0.17473 % | Collier (Earl M Jr) | 56,856 | 30,000 | |
0.16793 % | Oppenheimer Asset Management Inc. | 54,646 | 54,646 | |
0.16011 % | Jump Financial, LLC | 52,100 | -3,813 | |
0.14842 % | Morgan Stanley Smith Barney LLC | 48,297 | 8,165 | |
0.12445 % | Susquehanna International Group, LLP | 40,497 | -275,763 | |
0.11174 % | Wells Fargo Advisors | 36,360 | 4,039 | |
0.10547 % | Nuveen LLC | 34,320 | 34,320 | |
0.09830 % | LPL Financial LLC | 31,988 | -14,350 | |
0.09613 % | Commonwealth Financial Network | 31,280 | 1,280 | |
0.09492 % | Rhumbline Advisers Ltd. Partnership | 30,886 | 30,886 | |
0.09224 % | Morgan Stanley & Co. LLC | 30,015 | -40,587 | |
0.08451 % | Main Street Financial Solutions, LLC | 27,500 | 7,500 | |
0.08399 % | GSA Capital Partners LLP | 27,330 | 27,330 | |
0.07729 % | Occudo Quantitative Strategies LP | 25,151 | -906 | |
0.07427 % | Alpine Global Management, LLC | 24,168 | 24,168 | |
0.07348 % | Two Sigma Investments, LP | 23,911 | -89 | |
0.06974 % | Squarepoint Capital LLP | 22,695 | 22,695 | |
0.06161 % | Krasney Karen | 20,047 | 0 | |
0.05802 % | Trexquant Investment LP | 18,879 | 18,879 | |
0.05764 % | Mellon Investments Corporation | 18,757 | 18,756 | |
0.05629 % | Jane Street Capital, L.L.C. | 18,316 | -74,344 | |
0.05548 % | Northern Trust Global Investments | 18,052 | -4,193 | |
0.05400 % | Barclays Bank PLC | 17,572 | 17,572 | |
0.05276 % | Simplex Trading, LLC | 17,169 | -8,028 | |
0.05082 % | BofA Global Research (US) | 16,537 | -5,465 | |
0.04733 % | Goldman Sachs Asset Management, L.P. | 15,402 | 162 | |
0.04435 % | Qube Research & Technologies Ltd | 14,433 | -54,970 | |
0.04345 % | Mirae Asset Global Investments (USA) LLC | 14,140 | -392 | |
0.04197 % | SunAmerica Asset Management, LLC | 13,656 | 0 | |
0.04197 % | Corebridge Financial Inc | 13,656 | 13,656 | |
0.04124 % | Engineers Gate Manager, L.P. | 13,419 | 13,419 | |
0.03594 % | Group One Trading, L.P. | 11,695 | 11,695 | |
0.03585 % | Invesco Advisers, Inc. | 11,664 | 11,664 | |
0.03461 % | Citi Investment Research (US) | 11,263 | -67,089 | |
0.03348 % | Coastal Bridge Advisors, LLC | 10,894 | 0 | |
0.03325 % | JPMorgan Private Bank (United States) | 10,818 | 10,818 | |
0.03244 % | Dunbar (George W Jr) | 10,556 | 0 | |
0.03073 % | Activest Wealth Management LLC | 10,000 | 10,000 | |
0.02927 % | Tower Research Capital LLC | 9,524 | 4,691 | |
0.02694 % | SG Americas Securities, L.L.C. | 8,765 | 8,765 | |
0.02670 % | UBS Financial Services, Inc. | 8,687 | 7,187 | |
0.02639 % | Wells Fargo Bank, N.A. | 8,586 | 8,345 | |
0.02293 % | U.S. Bancorp Asset Management, Inc. | 7,462 | 0 | |
0.02268 % | AllianceBernstein L.P. | 7,380 | 0 | |
0.01936 % | Hightower Advisors, LLC | 6,301 | 5,400 | |
0.01537 % | Auwaerter (Paul Gisbert) | 5,000 | 0 | |
0.01463 % | ProShare Advisors LLC | 4,760 | -118 | |
0.01057 % | RBC Dominion Securities, Inc. | 3,440 | 2,040 | |
0.00855 % | Principal Global Investors (Equity) | 2,781 | 0 | |
0.00837 % | Legal & General Investment Management Ltd. | 2,725 | 2,725 | |
0.00764 % | Ameritas Investment Partners, Inc. | 2,487 | 2,487 | |
0.00734 % | RBC Wealth Management, International | 2,387 | 2,387 | |
0.00732 % | Bergmann (Anthony) | 2,381 | 0 | |
0.00650 % | BlackRock Fund Advisors | 2,116 | 0 | |
0.00594 % | Desjardins Securities Inc. | 1,932 | 0 | |
0.00565 % | California State Teachers Retirement System | 1,839 | 1,839 | |
0.00561 % | BNP Paribas Securities Corp. North America | 1,827 | -4,000 | |
0.00551 % | Assenagon Asset Management S.A. | 1,793 | 448 | |
0.00461 % | Householder Group Estate and Retirement Specialist LLC | 1,500 | 0 | |
0.00350 % | Horizon Kinetics LLC | 1,139 | 0 | |
0.00340 % | Franklin Mutual Advisers, LLC | 1,107 | 0 | |
0.00271 % | Parametric Portfolio Associates LLC | 883 | 883 | |
0.00270 % | Amalgamated Bank Institutional Asset Management & Custody | 878 | 878 | |
0.00246 % | New York State Common Retirement Fund | 800 | -20,800 | |
0.00230 % | Manulife Investment Management (North America) Limited | 749 | 0 | |
0.00212 % | Harel Insurance Investments and Financial Services Ltd | 689 | 0 | |
0.00144 % | Invesco Capital Management LLC | 470 | 470 | |
0.00131 % | Carson Wealth Management Group | 427 | 427 | |
0.00121 % | Signaturefd, LLC | 393 | 0 | |
0.00114 % | Guggenheim Investments | 372 | 0 | |
0.00101 % | City National Rochdale, LLC | 330 | 330 | |
0.00061 % | RBC Capital Markets Wealth Management | 200 | 200 | |
0.00056 % | Lazard Asset Management, L.L.C. | 181 | -2,512 | |
0.00049 % | ProFund Advisors LLC | 161 | 161 | |
0.00018 % | New Millennium Group LLC | 59 | 59 | |
0.00006 % | Northwestern Mutual Capital, LLC | 19 | 19 | |
0 % | ExodusPoint Capital Management, LP | 0 | -24,570 | |
0 % | Point72 Asia (Singapore) Pte. Ltd. | 0 | -23,678 | |
0 % | HRT Financial LP | 0 | -82,557 | |
0 % | Cubist Systematic Strategies, LLC | 0 | -54,268 | |