9.86712 % | T. Rowe Price Associates, Inc. | 6,250,823 | 901,584 | |
9.63385 % | The Vanguard Group, Inc. | 6,103,041 | 147,579 | |
7.41821 % | BlackRock Institutional Trust Company, N.A. | 4,699,435 | 134,745 | |
6.75033 % | Wellington Management Company, LLP | 4,276,333 | -804,188 | |
5.38000 % | Fidelity Management & Research Company LLC | 3,408,228 | -1,361,897 | |
4.54865 % | Rock Springs Capital Management LP | 2,881,567 | 196,273 | |
3.82668 % | State Street Global Advisors (US) | 2,424,200 | -201,427 | |
2.76803 % | Pictet Asset Management Ltd. | 1,753,547 | 997,219 | |
2.72746 % | William Blair Investment Management, LLC | 1,727,845 | 271,216 | |
2.52374 % | T. Rowe Price Investment Management, Inc. | 1,598,789 | -859,380 | |
2.47663 % | Macquarie Investment Management | 1,568,947 | -10,895 | |
2.28795 % | Lord, Abbett & Co. LLC | 1,449,414 | 987,493 | |
2.14362 % | AllianceBernstein L.P. | 1,357,983 | -139,271 | |
2.09512 % | Geode Capital Management, L.L.C. | 1,327,256 | 60,759 | |
1.93434 % | BlackRock Financial Management, Inc. | 1,225,404 | -116,566 | |
1.52436 % | Morgan Stanley & Co. LLC | 965,681 | 771,354 | |
1.48395 % | Fidelity Institutional Asset Management | 940,083 | -375,047 | |
1.36543 % | Polar Capital LLP | 865,000 | -175,000 | |
1.35938 % | JP Morgan Asset Management | 861,169 | -181,064 | |
1.33652 % | Emerald Advisers LLC | 846,686 | -224,672 | |
1.28567 % | Woodline Partners LP | 814,473 | 212,446 | |
1.12349 % | American Century Investment Management, Inc. | 711,734 | 40,762 | |
1.07328 % | Brown Advisory | 679,920 | 38,881 | |
0.97080 % | Avidity Partners Management LP | 615,000 | -136,600 | |
0.95651 % | Norges Bank Investment Management (NBIM) | 605,951 | -28,094 | |
0.84692 % | Alkeon Capital Management LLC | 536,525 | -252,192 | |
0.81595 % | Northern Trust Investments, Inc. | 516,904 | 9,547 | |
0.76157 % | JPMorgan Asset Management U.K. Limited | 482,457 | -106,070 | |
0.75148 % | Charles Schwab Investment Management, Inc. | 476,063 | 7,646 | |
0.69458 % | Hood River Capital Management LLC | 440,018 | 166,105 | |
0.59679 % | AHL Partners LLP | 378,064 | 378,064 | |
0.58370 % | BlackRock Investment Management (UK) Ltd. | 369,776 | -36,378 | |
0.58207 % | Pictet Asset Management (Japan) Ltd. | 368,743 | 85,500 | |
0.56689 % | Novo Holdings A/S | 359,126 | -165,874 | |
0.55141 % | D. E. Shaw & Co., L.P. | 349,317 | 335,279 | |
0.51716 % | Goldman Sachs & Company, Inc. | 327,621 | 95,310 | |
0.51565 % | Fisher Investments | 326,664 | -55,249 | |
0.51520 % | Casdin Capital, LLC | 326,378 | -45,000 | |
0.49309 % | Eventide Asset Management, LLC | 312,374 | -126,126 | |
0.46711 % | TD Asset Management Inc. | 295,916 | -20,388 | |
0.42701 % | PanAgora Asset Management Inc. | 270,510 | 7,122 | |
0.42566 % | Assenagon Asset Management S.A. | 269,658 | 260,321 | |
0.41267 % | Nuveen LLC | 261,427 | 88,564 | |
0.40225 % | Aquilo Capital Management, LLC | 254,827 | -124,263 | |
0.38987 % | Goldman Sachs Asset Management, L.P. | 246,984 | 134,577 | |
0.37032 % | Invesco Advisers, Inc. | 234,600 | 203,858 | |
0.36527 % | Eagle Asset Management, Inc. | 231,396 | 22,279 | |
0.35537 % | Ensign Peak Advisors, Inc. | 225,124 | 196,984 | |
0.32610 % | UBS Asset Management (Switzerland) | 206,585 | -2,591 | |
0.28911 % | BlackRock Investment Management, LLC | 183,151 | 6,635 | |
0.28885 % | Invesco Capital Management LLC | 182,984 | 141,696 | |
0.28202 % | Citi Investment Research (US) | 178,657 | 107,205 | |
0.26442 % | Granahan Investment Management, LLC | 167,507 | -61,740 | |
0.26283 % | BNY Mellon Asset Management | 166,501 | -1,558 | |
0.23945 % | BNP Paribas Securities Corp. North America | 151,693 | 71,812 | |
0.23016 % | Barclays Bank PLC | 145,804 | 27,475 | |
0.22256 % | Voloridge Investment Management, LLC | 140,989 | 140,989 | |
0.22099 % | Integral Health Asset Management, LLC | 140,000 | 90,000 | |
0.21463 % | Manulife Investment Management (North America) Limited | 135,969 | 4,746 | |
0.21361 % | Managed Account Advisors LLC | 135,323 | -90,983 | |
0.20687 % | Victory Capital Management Inc. | 131,050 | 124,517 | |
0.20228 % | Albers (Jeffrey W) | 128,142 | -11,033 | |
0.19974 % | UBS Financial Services, Inc. | 126,538 | 61,486 | |
0.19771 % | Segall Bryant & Hamill, LLC | 125,249 | 30,099 | |
0.19158 % | Rafferty Asset Management LLC | 121,368 | -45,322 | |
0.17916 % | Schweizerische Nationalbank | 113,500 | -19,400 | |
0.17500 % | Dafna Capital Management, LLC | 110,863 | -138,658 | |
0.16954 % | Oppenheimer Asset Management Inc. | 107,403 | -47,808 | |
0.16717 % | HOOPP Investment Management | 105,900 | 105,900 | |
0.16114 % | Voya Investment Management LLC | 102,082 | -53,221 | |
0.15844 % | Jane Street Capital, L.L.C. | 100,372 | 83,273 | |
0.15808 % | Millennium Management LLC | 100,145 | -755,889 | |
0.15630 % | Morgan Stanley Smith Barney LLC | 99,014 | 7,586 | |
0.15441 % | Susquehanna Portfolio Strategies, LLC | 97,817 | 97,817 | |
0.15047 % | Citadel Advisors LLC | 95,325 | 408 | |
0.14721 % | EFG Asset Management (UK) Limited | 93,258 | 4,148 | |
0.14663 % | Cowen Investment Management LLC | 92,888 | 92,888 | |
0.14487 % | Peregrine Capital Management, LLC | 91,773 | -54,890 | |
0.14165 % | BofA Global Research (US) | 89,738 | -80,379 | |
0.14087 % | Susquehanna International Group, LLP | 89,243 | -226,338 | |
0.13938 % | J.P. Morgan Securities LLC | 88,298 | 74,604 | |
0.13686 % | California Public Employees' Retirement System | 86,701 | -4,525 | |
0.13317 % | Rhumbline Advisers Ltd. Partnership | 84,366 | -836 | |
0.13195 % | Parametric Portfolio Associates LLC | 83,593 | 22,755 | |
0.13183 % | JPMorgan Private Bank (United States) | 83,514 | 40,539 | |
0.13065 % | Mellon Investments Corporation | 82,766 | -7,575 | |
0.12860 % | BlackRock Advisors (UK) Limited | 81,465 | 2,836 | |
0.12625 % | Dimensional Fund Advisors, L.P. | 79,979 | -91,684 | |
0.12583 % | T. Rowe Price International Ltd | 79,716 | 3,136 | |
0.11914 % | MFS Investment Management | 75,475 | 7,219 | |
0.11537 % | Haviland (Kathryn) | 73,085 | 27,536 | |
0.11348 % | Blue Owl Capital Holdings LP | 71,888 | 71,888 | |
0.11284 % | Driehaus Capital Management, LLC | 71,484 | 71,484 | |
0.10942 % | Borisy (Alexis) | 69,318 | 2,600 | |
0.10882 % | Allianz Global Investors U.S. LLC_NLE | 68,940 | 0 | |
0.10793 % | Credit Suisse Funds AG | 68,371 | 170 | |
0.10734 % | Nomura Asset Management Co., Ltd. | 68,000 | 68,000 | |
0.10106 % | BlackRock Asset Management Ireland Limited | 64,020 | 4,888 | |
0.09690 % | California State Teachers Retirement System | 61,387 | -5,503 | |
0.09616 % | Columbia Threadneedle Investments (US) | 60,916 | 8,726 | |