13.00464 % | CPMG, Inc. | 6,183,603 | 2,219,962 | |
9.98999 % | Nantahala Capital Management, LLC | 4,750,161 | 693,534 | |
7.83732 % | Stonepine Capital Management, LLC | 3,726,584 | 0 | |
5.01913 % | Citi Investment Research (US) | 2,386,557 | 376,119 | |
3.68040 % | Deerfield Management Company, L.P. | 1,750,000 | 0 | |
3.46051 % | Archon Capital Management LLC | 1,645,443 | -196,641 | |
3.11922 % | Lytton (Laurence W) | 1,483,162 | 1,183,979 | |
3.08600 % | The Vanguard Group, Inc. | 1,467,367 | 105,589 | |
2.25945 % | J.P. Morgan Securities LLC | 1,074,350 | 1,074,350 | |
1.65473 % | AWM Investment Company, Inc. | 786,809 | -43,288 | |
1.60423 % | Woodline Partners LP | 762,800 | 762,800 | |
1.51090 % | Boone Capital Management LLC | 718,419 | 718,419 | |
1.50894 % | Gagnon Securities LLC | 717,490 | -985,685 | |
1.31443 % | Berry Street Capital Management LLP | 625,000 | 625,000 | |
1.10859 % | Parian Global Management LP | 527,126 | -205,840 | |
1.07916 % | Gabelli Funds, LLC | 513,131 | 510,631 | |
1.06318 % | BlackRock Institutional Trust Company, N.A. | 505,532 | -57,854 | |
0.99826 % | Vivaldi Asset Management, LLC | 474,664 | 474,664 | |
0.94562 % | Water Island Capital, LLC | 449,636 | 90,636 | |
0.92517 % | Millennium Management LLC | 439,913 | 388,982 | |
0.87319 % | Magnetar Capital Partners LP | 415,194 | 415,194 | |
0.78446 % | Gilder Gagnon Howe & Co. LLC | 373,005 | -88,582 | |
0.78304 % | Geode Capital Management, L.L.C. | 372,329 | 28,878 | |
0.71337 % | Morgan Stanley & Co. LLC | 339,200 | 339,200 | |
0.69768 % | IndexIQ Advisors LLC | 331,741 | 331,741 | |
0.64775 % | Federated Hermes Global Investment Management Corp. | 308,000 | 308,000 | |
0.60157 % | Qube Research & Technologies Ltd | 286,040 | 286,040 | |
0.55989 % | Newton (K Todd) | 266,223 | 125,817 | |
0.54115 % | Bardin Hill Investment Partners LP | 257,312 | 257,312 | |
0.50209 % | AIGH Capital Management, LLC. | 238,740 | -143,261 | |
0.46976 % | McKhann (Charles S.) | 223,365 | 63,943 | |
0.44081 % | Renaissance Technologies LLC | 209,600 | 114,300 | |
0.41360 % | TIG Advisors, L.L.C. | 196,665 | 196,665 | |
0.36846 % | Bridgeway Capital Management, LLC | 175,200 | 0 | |
0.35752 % | Apis Capital Advisors LLC | 170,000 | 30,000 | |
0.34846 % | GWM Asset Management, Ltd. | 165,691 | 165,691 | |
0.34269 % | Glazer Capital, LLC | 162,947 | 162,947 | |
0.34180 % | Susquehanna International Group, LLP | 162,525 | 162,525 | |
0.33957 % | Russell Investments Trust Company | 161,463 | -77,370 | |
0.32335 % | Cigogne Management S.A. | 153,750 | 153,750 | |
0.31231 % | Northern Trust Investments, Inc. | 148,499 | 3,585 | |
0.29233 % | BCK Capital Management LP | 139,000 | 139,000 | |
0.28670 % | Boston Partners | 136,323 | -32,210 | |
0.27340 % | New Jersey Division of Investment | 130,000 | 0 | |
0.24809 % | State Street Global Advisors (US) | 117,966 | 28,600 | |
0.23902 % | Cavanaugh (Stefanie L CPA) | 113,653 | 70,993 | |
0.23049 % | Anderson (Rick D) | 109,596 | 14,224 | |
0.21820 % | Black (Jeffrey G) | 103,750 | -38,900 | |
0.16950 % | HRT Financial LP | 80,598 | 80,598 | |
0.16720 % | Goldman Sachs & Company, Inc. | 79,502 | -746,980 | |
0.16340 % | Worth Venture Partners, LLC | 77,696 | -48,839 | |
0.14665 % | Goldman Sachs Bank AG | 69,731 | 0 | |
0.12881 % | Dimensional Fund Advisors, L.P. | 61,247 | -5,142 | |
0.10597 % | Molesphini (John J) | 50,386 | 23,106 | |
0.10561 % | CSS, LLC | 50,215 | 50,215 | |
0.10515 % | Neuberger Berman, LLC | 50,000 | 0 | |
0.10515 % | Harvest Management, LLC | 50,000 | 50,000 | |
0.10299 % | Trexquant Investment LP | 48,973 | 48,973 | |
0.10114 % | Northern Trust Global Investments | 48,090 | 0 | |
0.09201 % | Maven Investment Partners US Ltd. | 43,751 | 43,751 | |
0.08740 % | Jane Street Capital, L.L.C. | 41,559 | 41,559 | |
0.08615 % | BofA Global Research (US) | 40,965 | 1,758 | |
0.08187 % | Newton Investment Management North America, LLC | 38,930 | 0 | |
0.07849 % | Crystalline Management, Inc. | 37,319 | 37,319 | |
0.07488 % | O'Keefe (Sharon L) | 35,604 | 35,604 | |
0.07483 % | Jump Financial, LLC | 35,582 | 24,382 | |
0.07430 % | UBS Financial Services, Inc. | 35,328 | 31,773 | |
0.06833 % | Trium Capital LLP | 32,488 | 32,488 | |
0.06562 % | University of Texas Investment Management Company | 31,202 | 0 | |
0.06279 % | Barr (John R) | 29,858 | -10,336 | |
0.05684 % | McClellan (William D Jr) | 27,025 | -10,336 | |
0.05678 % | Thompson, Davis & Co., Inc. (Asset Management) | 27,000 | -47,078 | |
0.05664 % | Schonfeld Strategic Advisors LLC | 26,931 | 26,931 | |
0.05074 % | Quantbot Technologies, LP | 24,125 | 24,125 | |
0.04584 % | Shimer (Julie Ann) | 21,797 | -10,336 | |
0.04127 % | Cubist Systematic Strategies, LLC | 19,623 | 19,623 | |
0.03735 % | Barclays Capital Inc. | 17,762 | 16,604 | |
0.03710 % | Bankes (Jeannette) | 17,641 | 14,224 | |
0.03617 % | Charles Schwab Investment Management, Inc. | 17,198 | 0 | |
0.03578 % | BNY Mellon Asset Management | 17,011 | 7,594 | |
0.03379 % | Lighthouse Partners | 16,065 | 16,065 | |
0.02923 % | Highland Capital Management Fund Advisors, L.P. | 13,900 | 13,900 | |
0.02734 % | Verition Fund Management LLC | 13,000 | 13,000 | |
0.02672 % | Balyasny Asset Management LP | 12,706 | 12,706 | |
0.02662 % | Squarepoint Capital LLP | 12,658 | 12,658 | |
0.02549 % | Mirabella Financial Services LLP | 12,120 | 12,120 | |
0.02345 % | Morris Financial Concepts, INC | 11,149 | 11,149 | |
0.02191 % | Citadel Advisors LLC | 10,417 | -55,610 | |
0.01414 % | Wolverine Asset Management, LLC | 6,724 | 6,724 | |
0.01301 % | BlackRock Investment Management, LLC | 6,186 | 554 | |
0.01301 % | Lord, Abbett & Co. LLC | 6,186 | 0 | |
0.01199 % | Lazard Asset Management, L.L.C. | 5,701 | -5,203 | |
0.00818 % | Pacitti (David) | 3,888 | -10,336 | |
0.00735 % | Tower Research Capital LLC | 3,495 | 3,231 | |
0.00486 % | Invesco Capital Management LLC | 2,312 | 0 | |
0.00411 % | Morgan Stanley Smith Barney LLC | 1,952 | 0 | |
0.00314 % | Morgan Stanley & Co. International Plc | 1,495 | 1,495 | |
0.00273 % | Cutler Group, LP | 1,300 | 1,300 | |
0.00215 % | BlackRock Financial Management, Inc. | 1,023 | -2,271 | |
0.00212 % | Russell Investments Limited | 1,006 | -937 | |