14.45329 % | ElevateBio LLC | 16,674,766 | 0 | |
14.41907 % | Gilead Sciences Inc | 16,635,286 | 0 | |
9.78988 % | EcoR1 Capital, LLC | 11,294,585 | 0 | |
9.70963 % | Octagon Capital Advisors LP | 11,202,000 | 1,402,000 | |
8.51876 % | F2 MG Ltd | 9,828,091 | 0 | |
5.71827 % | Invus Public Equities Advisors, LLC | 6,597,167 | 0 | |
4.64235 % | Wilson (John Robert) | 5,355,877 | 0 | |
2.85666 % | Millennium Management LLC | 3,295,729 | 353,121 | |
2.60274 % | Hallal (David L) | 3,002,780 | 35,000 | |
2.29437 % | The Vanguard Group, Inc. | 2,647,010 | -275,444 | |
2.08887 % | Vera (Juan F. M.D.) | 2,409,928 | 35,000 | |
1.65378 % | Redmile Group, LLC | 1,907,969 | 0 | |
1.01929 % | Acadian Asset Management LLC | 1,175,954 | -411,497 | |
1.00024 % | SunAmerica Asset Management, LLC | 1,153,976 | -217 | |
0.96462 % | Sinha (Vikas) | 1,112,879 | -4,368 | |
0.85462 % | Two Sigma Investments, LP | 985,975 | 369,729 | |
0.85363 % | Acuitas Investments LLC | 984,833 | 5,233 | |
0.68579 % | Renaissance Technologies LLC | 791,200 | -70,294 | |
0.56122 % | Geode Capital Management, L.L.C. | 647,477 | -626,445 | |
0.54793 % | BlackRock Institutional Trust Company, N.A. | 632,152 | -2,493,931 | |
0.52274 % | BML Capital Management LLC | 603,086 | 402,622 | |
0.43599 % | Miller Edward | 503,002 | -1,778 | |
0.41708 % | Brainard (Diana) | 481,188 | -11,245 | |
0.41223 % | D. E. Shaw & Co., L.P. | 475,585 | -394,277 | |
0.38919 % | RBF Capital, LLC | 449,014 | 449,014 | |
0.34372 % | Northern Trust Investments, Inc. | 396,550 | -9,069 | |
0.29866 % | Charles Schwab Investment Management, Inc. | 344,562 | -116,264 | |
0.28141 % | Marshall Wace LLP | 324,658 | -40,478 | |
0.26771 % | Fidelity Management & Research Company LLC | 308,860 | 37,023 | |
0.22877 % | Brenner (Malcolm) | 263,929 | 35,000 | |
0.20672 % | Goldman Sachs & Company, Inc. | 238,498 | 113,469 | |
0.19280 % | State Street Global Advisors (US) | 222,439 | -955,817 | |
0.18696 % | Pennant Investors, LP | 215,700 | 0 | |
0.17422 % | Commonwealth Financial Network | 201,000 | 0 | |
0.16856 % | Y-Intercept (Hong Kong) Ltd | 194,473 | 194,473 | |
0.15505 % | Marquette Wealth Management | 178,883 | 0 | |
0.14998 % | Jane Street Capital, L.L.C. | 173,031 | 173,031 | |
0.14571 % | Susquehanna International Group, LLP | 168,106 | 76,411 | |
0.12742 % | Piccina (Cintia) | 147,000 | 147,000 | |
0.11953 % | Centiva Capital, LP | 137,897 | 137,897 | |
0.10749 % | Leen (Ann M) | 124,006 | 43,750 | |
0.09552 % | Bornstein (Jeffrey S) | 110,197 | 35,000 | |
0.09299 % | Citadel Advisors LLC | 107,278 | -38,922 | |
0.08685 % | Jovan-Embiricos Morana | 100,197 | 35,000 | |
0.07446 % | T. Rowe Price International Ltd | 85,900 | -12,086 | |
0.07434 % | AQR Capital Management, LLC | 85,768 | -7,991 | |
0.07137 % | Samsara BioCapital, LLC | 82,336 | 0 | |
0.06884 % | Lido Advisors, LLC | 79,416 | 0 | |
0.06831 % | Qube Research & Technologies Ltd | 78,812 | -28,846 | |
0.06612 % | Point72 Asia (Singapore) Pte. Ltd. | 76,278 | 76,278 | |
0.06249 % | Andbank Wealth Management, SGIIC, S.A.U. | 72,098 | 0 | |
0.06067 % | Adams (Derek N) | 70,000 | 35,000 | |
0.06067 % | Tomasello (Shawn Cline) | 70,000 | 35,000 | |
0.06047 % | Dimensional Fund Advisors, L.P. | 69,769 | 0 | |
0.05895 % | Hagen (Brett R.) | 68,005 | -1,266 | |
0.05622 % | Morgan Stanley Smith Barney LLC | 64,860 | -217,751 | |
0.05282 % | UBS Asset Management (Americas), Inc. | 60,936 | 0 | |
0.05244 % | Raymond James Financial Services Advisors, Inc. | 60,500 | 0 | |
0.04440 % | GSA Capital Partners LLP | 51,224 | -175,403 | |
0.04318 % | Cubist Systematic Strategies, LLC | 49,816 | 30,072 | |
0.04301 % | Tudor Investment Corporation | 49,620 | 0 | |
0.04290 % | Goldman Sachs Asset Management, L.P. | 49,492 | 14,028 | |
0.04094 % | XTX Markets LLC | 47,233 | 773 | |
0.03535 % | Northern Trust Global Investments | 40,781 | -3,075 | |
0.03231 % | UBS Financial Services, Inc. | 37,281 | -18,215 | |
0.02765 % | Dimensional Fund Advisors, Ltd. | 31,896 | 0 | |
0.02753 % | Paloma Partners Management Company | 31,765 | 31,765 | |
0.02256 % | Mirae Asset Global Investments (USA) LLC | 26,032 | 13,916 | |
0.01977 % | Vaughan Nelson Investment Management, L.P. | 22,808 | 0 | |
0.01935 % | BofA Global Research (US) | 22,328 | -23,053 | |
0.01925 % | Vanguard Personalized Indexing Management, LLC | 22,210 | -6,228 | |
0.01826 % | State Street Global Advisors Ireland Limited | 21,065 | -77 | |
0.01782 % | Tower Research Capital LLC | 20,558 | 10,386 | |
0.01603 % | Rhumbline Advisers Ltd. Partnership | 18,494 | -50,505 | |
0.01493 % | Point72 (DIFC) Ltd | 17,227 | 17,227 | |
0.01397 % | Engineers Gate Manager, L.P. | 16,114 | 0 | |
0.01387 % | PFG Investments, LLC | 16,000 | -3,000 | |
0.01382 % | Balyasny Asset Management LP | 15,947 | 15,947 | |
0.01320 % | Federated MDTA LLC | 15,230 | 25 | |
0.01300 % | Osaic Holdings, Inc. | 15,000 | 0 | |
0.01262 % | Jump Financial, LLC | 14,565 | 14,565 | |
0.00702 % | Blackstone Alternative Investment Advisors LLC | 8,100 | 4,600 | |
0.00663 % | Citi Investment Research (US) | 7,645 | -2,802 | |
0.00537 % | Hoopoe Advisors | 6,200 | 0 | |
0.00494 % | RBC Capital Markets Wealth Management | 5,700 | 5,700 | |
0.00491 % | JP Morgan Asset Management | 5,668 | -2,878 | |
0.00309 % | Mackenzie Investments | 3,566 | -4 | |
0.00260 % | Independent Financial Partners | 3,000 | 3,000 | |
0.00250 % | T. Rowe Price Associates, Inc. | 2,887 | -1,200 | |
0.00236 % | Morgan Stanley & Co. International Plc | 2,721 | 1,841 | |
0.00222 % | Macquarie Investment Management Global Ltd. | 2,561 | 2,561 | |
0.00181 % | RBC Wealth Management, International | 2,084 | 944 | |
0.00164 % | Morgan Stanley & Co. LLC | 1,892 | -65,396 | |
0.00131 % | RBC Capital Partners | 1,510 | 1,454 | |
0.00102 % | BlackRock (Netherlands) B.V. | 1,181 | 0 | |
0.00099 % | Parallel Advisors, LLC | 1,145 | 0 | |
0.00095 % | J.P. Morgan Securities plc | 1,094 | 0 | |
0.00087 % | Carson Wealth Management Group | 1,004 | -1,271 | |
0.00075 % | Farther Finance Advisors, LLC | 862 | 0 | |
0.00060 % | EverSource Wealth Advisors, LLC | 695 | -634 | |