10.03904 % | Bain Capital Life Sciences Investors, LLC | 1,69,15,784 | 9,55,196 | 31/12/2023 |
8.89424 % | New Enterprise Associates (NEA) | 1,49,86,793 | 0 | 31/12/2023 |
4.75304 % | The Vanguard Group, Inc. | 80,08,865 | 1,84,148 | 31/12/2023 |
4.61187 % | BlackRock Institutional Trust Company, N.A. | 77,71,007 | 2,60,683 | 31/12/2023 |
4.23354 % | OrbiMed Advisors, LLC | 71,33,515 | 0 | 31/12/2023 |
2.53787 % | Adage Capital Management, L.P. | 42,76,315 | 0 | 31/12/2023 |
2.12963 % | Sio Capital Management, LLC | 35,88,427 | 9,89,424 | 31/12/2023 |
2.10413 % | Perceptive Advisors LLC | 35,45,454 | 0 | 31/12/2023 |
2.06153 % | Kingdon Capital Management, L.L.C. | 34,73,683 | 15,00,000 | 31/12/2023 |
1.82405 % | AXA Investment Managers UK Ltd. | 30,73,532 | -74,333 | 31/12/2023 |
1.80800 % | Acorn Bioventures L.P. | 30,46,472 | 0 | 31/12/2023 |
1.66317 % | Geode Capital Management, L.L.C. | 28,02,449 | 1,59,534 | 31/12/2023 |
1.63578 % | Medical Strategy GmbH | 27,56,296 | 0 | 31/12/2023 |
1.44082 % | State Street Global Advisors (US) | 24,27,789 | 49,163 | 31/12/2023 |
1.14896 % | Armistice Capital LLC | 19,36,000 | -4,20,000 | 31/12/2023 |
1.03444 % | UBS O'Connor LLC | 17,43,038 | 1,83,052 | 31/12/2023 |
1.02556 % | Citadel Advisors LLC | 17,28,065 | -70,563 | 31/12/2023 |
0.98773 % | Millennium Management LLC | 16,64,317 | -19,51,647 | 31/12/2023 |
0.57351 % | Northern Trust Investments, Inc. | 9,66,363 | 4,792 | 31/12/2023 |
0.56093 % | GSA Capital Partners LLP | 9,45,171 | 3,23,584 | 31/12/2023 |
0.45539 % | Parkman Healthcare Partners LLC | 7,67,332 | -32,668 | 31/12/2023 |
0.38576 % | Point72 Asset Management, L.P. | 6,50,000 | 0 | 31/12/2023 |
0.35992 % | Ragan (Paula) | 6,06,464 | -49,678 | 11/3/2024 |
0.32599 % | Schonfeld Strategic Advisors LLC | 5,49,300 | -36,742 | 31/12/2023 |
0.31751 % | Propel Bio Management, LLC | 5,35,000 | 1,35,000 | 31/12/2023 |
0.31430 % | Barclays Bank PLC | 5,29,601 | 1,47,467 | 31/12/2023 |
0.26001 % | Nuveen LLC | 4,38,114 | 0 | 31/12/2023 |
0.23912 % | Susquehanna International Group, LLP | 4,02,921 | 2,97,714 | 31/12/2023 |
0.23739 % | Simplify Asset Management Inc | 4,00,000 | 0 | 31/12/2023 |
0.23048 % | Royce Investment Partners | 3,88,363 | 2,69,357 | 31/12/2023 |
0.20846 % | BlackRock Investment Management, LLC | 3,51,262 | 0 | 31/12/2023 |
0.20605 % | Morgan Stanley & Co. LLC | 3,47,188 | 2,75,251 | 31/12/2023 |
0.19881 % | New Leaf Venture Partners LLC | 3,35,000 | 0 | 31/12/2023 |
0.19219 % | Charles Schwab Investment Management, Inc. | 3,23,843 | 0 | 31/12/2023 |
0.18486 % | SV Health Investors, LLC | 3,11,490 | 0 | 30/9/2022 |
0.17523 % | BlackRock Financial Management, Inc. | 2,95,255 | 0 | 31/12/2023 |
0.17477 % | BNY Mellon Asset Management | 2,94,492 | -1,28,739 | 31/12/2023 |
0.16828 % | BNP Paribas Securities Corp. North America | 2,83,544 | 2,36,899 | 31/12/2023 |
0.13905 % | Taveras (Arthur PhD) | 2,34,301 | -14,235 | 11/3/2024 |
0.13531 % | Mostafa (Adam S.) | 2,28,004 | 2,22,587 | 31/10/2023 |
0.12634 % | BofA Global Research (US) | 2,12,888 | -1,60,305 | 31/12/2023 |
0.12292 % | Dibiase (Mary) | 2,07,128 | -15,409 | 11/3/2024 |
0.10778 % | Acadian Asset Management LLC | 1,81,609 | 1,81,609 | 31/12/2023 |
0.09753 % | AQR Capital Management, LLC | 1,64,342 | 1,03,053 | 31/12/2023 |
0.09518 % | Rhumbline Advisers Ltd. Partnership | 1,60,370 | 0 | 31/12/2023 |
0.08497 % | Stewart (Murray) | 1,43,170 | 1,39,837 | 10/8/2023 |
0.07672 % | Jane Street Capital, L.L.C. | 1,29,274 | 1,15,907 | 31/12/2023 |
0.07580 % | Virtu Americas LLC | 1,27,718 | 1,27,718 | 31/12/2023 |
0.07080 % | Knott Partners Management, LLC | 1,19,300 | 1,19,300 | 31/12/2023 |
0.05734 % | Northern Trust Global Investments | 96,622 | -9,500 | 31/12/2023 |
0.05368 % | Stifel, Nicolaus & Company, Incorporated | 90,452 | 10,174 | 31/12/2023 |
0.05341 % | Woods (Keith) | 90,000 | 90,000 | 16/10/2023 |
0.04825 % | Amundi Asset Management, SAS | 81,305 | 0 | 31/12/2023 |
0.04736 % | JPMorgan Private Bank (United States) | 79,805 | 79,805 | 31/12/2023 |
0.04352 % | Wyzga (Michael S) | 73,333 | 25,000 | 18/8/2023 |
0.04200 % | Group One Trading, L.P. | 70,764 | -1,55,597 | 31/12/2023 |
0.04100 % | XTX Markets LLC | 69,086 | 69,086 | 31/12/2023 |
0.03844 % | Squarepoint Capital LLP | 64,763 | 64,763 | 31/12/2023 |
0.03632 % | SunAmerica Asset Management, LLC | 61,198 | -247 | 31/12/2023 |
0.03282 % | Dimensional Fund Advisors, L.P. | 55,296 | 0 | 31/12/2023 |
0.03243 % | Invesco Advisers, Inc. | 54,649 | 1,620 | 31/12/2023 |
0.03159 % | Morgan Stanley Smith Barney LLC | 53,235 | 10,800 | 31/12/2023 |
0.03059 % | New York State Common Retirement Fund | 51,551 | -417 | 31/12/2023 |
0.03054 % | Mellon Investments Corporation | 51,462 | 0 | 31/12/2023 |
0.02923 % | Voya Investment Management LLC | 49,260 | 0 | 31/12/2023 |
0.02868 % | Aliski (William) | 48,333 | 45,000 | 13/6/2023 |
0.02868 % | Lawton (Alison Frances) | 48,333 | 45,000 | 13/6/2023 |
0.02868 % | Bridger (Gary J) | 48,333 | 45,000 | 13/6/2023 |
0.02868 % | McGirr (David W J) | 48,333 | 45,000 | 13/6/2023 |
0.02868 % | de (Craecker Francoise) | 48,333 | 45,000 | 13/6/2023 |
0.02829 % | SG Americas Securities, L.L.C. | 47,668 | 13,328 | 31/12/2023 |
0.02754 % | Goldman Sachs & Company, Inc. | 46,404 | 26,689 | 31/12/2023 |
0.02711 % | AllianceBernstein L.P. | 45,680 | 0 | 31/12/2023 |
0.02671 % | Bank Vontobel AG | 45,000 | 0 | 31/12/2023 |
0.02671 % | CIBC Private Wealth Management | 45,000 | 0 | 31/12/2023 |
0.02479 % | Invesco Capital Management LLC | 41,777 | 13,777 | 31/12/2023 |
0.02338 % | Bayesian Capital Management, LP | 39,400 | 39,400 | 31/12/2023 |
0.02079 % | Wells Fargo Bank, N.A. | 35,024 | 7,396 | 31/12/2023 |
0.01898 % | Florida State Board of Administration | 31,979 | 31,979 | 31/12/2023 |
0.01790 % | PNC Investments LLC | 30,158 | -192 | 31/12/2023 |
0.01758 % | Walleye Capital LLC | 29,616 | 29,616 | 31/12/2023 |
0.01590 % | T. Rowe Price International Ltd | 26,793 | 0 | 31/12/2023 |
0.01566 % | Goldman Sachs Asset Management, L.P. | 26,384 | -3,494 | 31/12/2023 |
0.01559 % | RBC Wealth Management, International | 26,264 | 8,221 | 31/12/2023 |
0.01531 % | OneDigital Investment Advisors LLC | 25,801 | -4,514 | 31/12/2023 |
0.01490 % | Commonwealth Financial Network | 25,100 | -1,650 | 31/12/2023 |
0.01473 % | Vaughan Nelson Investment Management, L.P. | 24,819 | 0 | 31/12/2023 |
0.01465 % | Baldry (Mark) | 24,690 | -10,257 | 1/11/2023 |
0.01294 % | Private Advisor Group LLC | 21,800 | 0 | 31/12/2023 |
0.01209 % | ProShare Advisors LLC | 20,378 | 4,383 | 31/12/2023 |
0.01203 % | California State Teachers Retirement System | 20,265 | -6,902 | 31/12/2023 |
0.01060 % | Bleichroeder LP | 17,865 | 0 | 31/12/2023 |
0.01046 % | Citi Investment Research (US) | 17,630 | 17,562 | 31/12/2023 |
0.01014 % | HRT Financial LP | 17,084 | 17,084 | 31/12/2023 |
0.01014 % | Victory Capital Management Inc. | 17,079 | 3,348 | 31/12/2023 |
0.00987 % | Principal Global Investors (Equity) | 16,626 | 299 | 31/12/2023 |
0.00950 % | Lexaurum Advisors, LLC | 16,000 | 0 | 31/3/2024 |
0.00890 % | Grimes & Company, Inc. | 15,000 | 0 | 31/3/2024 |
0.00836 % | Amalgamated Bank Institutional Asset Management & Custody | 14,086 | -1,235 | 31/12/2023 |
0.00790 % | Mackenzie Financial Corporation | 13,316 | -50 | 31/12/2023 |