8.83 % | Franklin Advisers, Inc. | 45,98,127 | 4,87,708 | 31/12/2023 |
8.58 % | Adage Capital Management, L.P. | 44,66,420 | 27,29,917 | 31/12/2023 |
7.79 % | Suvretta Capital Management, LLC | 40,56,847 | 5,64,700 | 31/12/2023 |
4.74 % | T. Rowe Price Associates, Inc. | 24,68,513 | 10,99,855 | 31/12/2023 |
4.49 % | EW Healthcare Partners | 23,37,786 | -11,53,135 | 31/12/2023 |
3.91 % | The Vanguard Group, Inc. | 20,34,060 | 5,93,336 | 31/12/2023 |
3.78 % | BlackRock Institutional Trust Company, N.A. | 19,68,721 | 3,71,954 | 31/12/2023 |
2.99 % | T. Rowe Price Investment Management, Inc. | 15,58,675 | 15,58,675 | 31/12/2023 |
2.80 % | Columbia Threadneedle Investments (US) | 14,58,367 | 14,48,018 | 31/12/2023 |
2.36 % | Citadel Advisors LLC | 12,27,278 | 1,68,231 | 31/12/2023 |
2.17 % | Millennium Management LLC | 11,28,638 | 5,48,009 | 31/12/2023 |
2.17 % | Morgan Stanley & Co. LLC | 11,28,285 | 10,60,344 | 31/12/2023 |
2.05 % | Jennison Associates LLC | 10,66,240 | 10,66,240 | 31/12/2023 |
13.24 % | Cormorant Asset Management, LP | 68,93,235 | 8,55,000 | 11/1/2024 |
1.31 % | Geode Capital Management, L.L.C. | 6,82,417 | 1,46,842 | 31/12/2023 |
1.30 % | Federated MDTA LLC | 6,74,824 | 4,45,289 | 31/12/2023 |
1.22 % | Laurion Capital Management LP | 6,33,409 | 6,33,409 | 31/12/2023 |
1.13 % | Perceptive Advisors LLC | 5,89,646 | 5,89,646 | 31/12/2023 |
1.10 % | UBS Financial Services, Inc. | 5,74,169 | 47,321 | 31/12/2023 |
1.08 % | DWS Investments UK Limited | 5,61,958 | 5,49,824 | 31/12/2023 |
1.06 % | State Street Global Advisors (US) | 5,50,609 | 17,554 | 31/12/2023 |
1.04 % | Goldman Sachs & Company, Inc. | 5,41,530 | -34,607 | 31/12/2023 |
0.82 % | Acuta Capital Partners, LLC | 4,25,128 | 1,25,000 | 31/12/2023 |
0.77 % | Oracle Investment Management, Inc. | 4,01,557 | 4,01,557 | 31/12/2023 |
0.77 % | Woodline Partners LP | 4,00,000 | 4,00,000 | 31/12/2023 |
0.71 % | Lord, Abbett & Co. LLC | 3,70,987 | 3,70,987 | 31/12/2023 |
0.71 % | Ikarian Capital LLC | 3,68,130 | 3,68,130 | 31/12/2023 |
0.61 % | First Turn Management, LLC | 3,17,010 | 3,17,010 | 31/12/2023 |
0.60 % | Candriam Luxembourg S.A. | 3,15,000 | 75,000 | 29/2/2024 |
0.55 % | AXA Investment Managers UK Ltd. | 2,87,143 | -6,948 | 31/12/2023 |
0.54 % | Invesco Capital Management LLC | 2,79,872 | 2,79,872 | 31/12/2023 |
0.53 % | Norges Bank Investment Management (NBIM) | 2,74,729 | 2,74,729 | 31/12/2023 |
0.51 % | Susquehanna International Group, LLP | 2,66,031 | 1,40,351 | 31/12/2023 |
0.48 % | VR Adviser, LLC | 2,50,000 | 2,50,000 | 31/12/2023 |
0.46 % | SEB Investment Management AB | 2,41,072 | 1,90,268 | 29/2/2024 |
0.43 % | Northern Trust Investments, Inc. | 2,22,705 | 29,808 | 31/12/2023 |
0.38 % | DWS Investment S.A. | 1,98,915 | 1,98,915 | 31/12/2023 |
0.36 % | Alyeska Investment Group, L.P. | 1,86,840 | 1,86,840 | 31/12/2023 |
0.35 % | Schroder Investment Management Ltd. (SIM) | 1,80,000 | 1,80,000 | 31/12/2023 |
0.34 % | Monashee Investment Management, LLC | 1,75,000 | 1,75,000 | 31/12/2023 |
0.33 % | Two Sigma Investments, LP | 1,73,682 | 77,252 | 31/12/2023 |
0.33 % | PFM Health Sciences, LP | 1,70,871 | 1,70,871 | 31/12/2023 |
0.32 % | Ghost Tree Capital, LLC | 1,65,000 | -1,60,000 | 31/12/2023 |
0.31 % | Barclays Bank PLC | 1,59,642 | 1,13,983 | 31/12/2023 |
0.28 % | Essex Investment Management Company, LLC | 1,47,541 | -59,619 | 31/12/2023 |
0.28 % | Paggiarino Dario A | 1,43,834 | 24,858 | 30/3/2024 |
0.27 % | TD Asset Management Inc. | 1,42,894 | 71,094 | 31/12/2023 |
0.27 % | Voloridge Investment Management, LLC | 1,40,705 | 1,40,705 | 31/12/2023 |
0.27 % | Candriam Belgium S.A. | 1,40,000 | 1,40,000 | 31/12/2023 |
0.27 % | EAM Investors, LLC | 1,38,310 | 1,38,310 | 31/12/2023 |
0.26 % | HOOPP Investment Management | 1,37,000 | 1,37,000 | 31/12/2023 |
0.25 % | Elston (George O) | 1,30,609 | 7,608 | 9/2/2024 |
0.24 % | Connor, Clark & Lunn Investment Management Ltd. | 1,23,764 | 1,23,764 | 31/12/2023 |
0.24 % | Nuveen LLC | 1,22,997 | -52,865 | 31/12/2023 |
0.22 % | Jones (David Scott) | 1,16,079 | 6,311 | 9/2/2024 |
0.22 % | PGIM Securities Investment Trust Enterprise | 1,16,000 | 1,16,000 | 31/12/2023 |
0.21 % | Affinity Asset Advisors LLC | 1,09,900 | 1,09,900 | 31/12/2023 |
0.21 % | Parametric Portfolio Associates LLC | 1,09,790 | 43,575 | 31/12/2023 |
0.21 % | Ghisallo Capital Management LLC | 1,08,634 | 1,08,634 | 31/12/2023 |
0.20 % | BlackRock Financial Management, Inc. | 1,01,578 | -49,498 | 31/12/2023 |
0.19 % | D. E. Shaw & Co., L.P. | 1,00,960 | 1,00,960 | 31/12/2023 |
0.19 % | Ocumension Therapeutics | 1,00,222 | -19,10,500 | 11/1/2024 |
0.18 % | StemPoint Capital LP | 95,732 | 95,732 | 31/12/2023 |
0.18 % | BNY Mellon Asset Management | 94,582 | 6,394 | 31/12/2023 |
0.18 % | Wellington Management Company, LLP | 94,561 | 94,561 | 31/12/2023 |
0.17 % | Boothbay Fund Management, LLC | 88,443 | 88,443 | 31/12/2023 |
0.16 % | Lurker (Nancy S) | 83,351 | -52,090 | 13/2/2024 |
0.16 % | Sectoral Asset Management Inc. | 81,160 | -94,920 | 31/12/2023 |
0.16 % | PanAgora Asset Management Inc. | 80,780 | 5,541 | 31/12/2023 |
0.15 % | Morgan Stanley Smith Barney LLC | 80,588 | 78,199 | 31/12/2023 |
0.15 % | BofA Global Research (US) | 78,444 | 70,884 | 31/12/2023 |
0.15 % | Charles Schwab Investment Management, Inc. | 78,410 | 6,862 | 31/12/2023 |
0.14 % | Manulife Investment Management (North America) Limited | 74,421 | 21,482 | 31/12/2023 |
0.14 % | Bridgeway Capital Management, LLC | 73,000 | -44,100 | 31/12/2023 |
0.14 % | Legato Capital Management LLC | 71,734 | 12,387 | 31/3/2024 |
0.13 % | BlackRock Investment Management, LLC | 69,957 | 314 | 31/12/2023 |
0.13 % | Jane Street Capital, L.L.C. | 69,895 | 39,672 | 31/12/2023 |
0.11 % | BlackRock Advisors (UK) Limited | 55,624 | 3,006 | 31/3/2024 |
0.10 % | T. Rowe Price International Ltd | 54,191 | 48,503 | 31/12/2023 |
0.10 % | Cubist Systematic Strategies, LLC | 54,022 | -81,137 | 31/12/2023 |
0.10 % | Nicholas Investment Partners, L.P. | 53,236 | 53,236 | 31/12/2023 |
0.10 % | Artia Global Partners LP | 50,000 | 50,000 | 31/12/2023 |
0.09 % | Trexquant Investment LP | 48,760 | -55,858 | 31/12/2023 |
0.09 % | Rhumbline Advisers Ltd. Partnership | 46,140 | 4,388 | 31/12/2023 |
0.09 % | Ratan Capital Management LP | 45,000 | 45,000 | 31/12/2023 |
0.08 % | Jacobs Levy Equity Management, Inc. | 43,761 | 0 | 31/12/2023 |
0.08 % | Franklin Equity Group | 42,524 | 3,300 | 31/12/2023 |
0.07 % | Deka Vermögensmanagement GmbH | 35,000 | 35,000 | 31/12/2023 |
0.06 % | Assenagon Asset Management S.A. | 33,135 | 2,411 | 29/2/2024 |
0.06 % | Fidelity Management & Research Company LLC | 32,485 | 30,088 | 31/12/2023 |
0.06 % | Occudo Quantitative Strategies LP | 32,176 | 32,176 | 31/12/2023 |
0.06 % | Woodstock Corporation | 30,778 | 8,525 | 31/3/2024 |
0.06 % | Hightower Advisors, LLC | 30,007 | -2,22,965 | 31/12/2023 |
0.06 % | Dimensional Fund Advisors, L.P. | 29,610 | -20,511 | 31/12/2023 |
0.06 % | Duker (Jay S) | 29,420 | -14,066 | 27/2/2024 |
0.05 % | Victory Capital Management Inc. | 28,530 | 28,530 | 31/12/2023 |
0.05 % | Goldman Sachs Asset Management, L.P. | 26,456 | 2,119 | 31/12/2023 |
0.05 % | Exome Asset Management LLC | 26,400 | 26,400 | 31/12/2023 |
0.05 % | BMO Capital Markets (US) | 25,400 | 25,400 | 31/12/2023 |
0.05 % | Simplex Trading, LLC | 24,450 | 24,450 | 31/12/2023 |