11.89781 % | PRIMECAP Management Company | 73,12,391 | -4,35,200 | 30/6/2024 |
10.41062 % | Baker Bros. Advisors LP | 63,98,365 | 0 | 30/6/2024 |
9.89979 % | RA Capital Management, LP | 60,84,412 | 7,54,000 | 30/6/2024 |
8.50647 % | Goldman Sachs & Company, Inc. | 52,28,074 | 2,23,252 | 30/6/2024 |
6.41041 % | BlackRock Institutional Trust Company, N.A. | 39,39,837 | 44,398 | 30/6/2024 |
5.60784 % | Perceptive Advisors LLC | 34,46,579 | 1,78,001 | 30/6/2024 |
5.45234 % | The Vanguard Group, Inc. | 33,51,010 | 56,549 | 30/6/2024 |
4.73472 % | New Enterprise Associates (NEA) | 29,09,956 | 0 | 30/6/2024 |
3.85829 % | Frazier Life Sciences Management, L.P. | 23,71,304 | 1,81,125 | 30/6/2024 |
3.26047 % | State Street Global Advisors (US) | 20,03,882 | -10,09,956 | 30/6/2024 |
2.70661 % | BlackRock Financial Management, Inc. | 16,63,485 | 48,190 | 30/6/2024 |
2.70221 % | Federated Hermes Global Investment Management Corp. | 16,60,780 | -220 | 30/6/2024 |
2.44061 % | Polar Capital LLP | 15,00,000 | 0 | 30/6/2024 |
2.08346 % | Rock Springs Capital Management LP | 12,80,493 | -2,42,400 | 30/6/2024 |
2.03822 % | Geode Capital Management, L.L.C. | 12,52,689 | 71,984 | 30/6/2024 |
1.99317 % | Commodore Capital LP | 12,25,000 | 1,75,000 | 30/6/2024 |
1.92380 % | Driehaus Capital Management, LLC | 11,82,370 | 3,26,865 | 30/6/2024 |
1.57378 % | HOOPP Investment Management | 9,67,243 | 2,36,600 | 30/6/2024 |
1.50033 % | Checkpoint Capital L.P. | 9,22,100 | 96,600 | 30/6/2024 |
1.35163 % | Alkeon Capital Management LLC | 8,30,712 | 8,30,712 | 30/6/2024 |
1.30458 % | Pictet Asset Management Ltd. | 8,01,796 | -4,09,883 | 30/6/2024 |
1.28904 % | BlackRock Investment Management (UK) Ltd. | 7,92,244 | 39,968 | 30/6/2024 |
1.14683 % | OrbiMed Advisors, LLC | 7,04,842 | 0 | 30/6/2024 |
0.96590 % | Janus Henderson Investors | 5,93,642 | -27,785 | 30/6/2024 |
0.83794 % | Opaleye Management Inc. | 5,15,000 | 0 | 30/6/2024 |
0.80163 % | T. Rowe Price Associates, Inc. | 4,92,682 | 42,212 | 30/6/2024 |
0.77286 % | Cormorant Asset Management, LP | 4,75,000 | -75,000 | 30/6/2024 |
0.75201 % | Voloridge Investment Management, LLC | 4,62,188 | -11,267 | 30/6/2024 |
0.70078 % | Northern Trust Investments, Inc. | 4,30,698 | -14,534 | 30/6/2024 |
0.69841 % | Morgan Stanley & Co. LLC | 4,29,244 | 2,85,267 | 30/6/2024 |
0.69632 % | Charles Schwab Investment Management, Inc. | 4,27,958 | 21,213 | 30/6/2024 |
0.67849 % | CPP Investment Board | 4,17,000 | -1,60,000 | 30/6/2024 |
0.65773 % | National Bank of Canada | 4,04,242 | 36,725 | 30/6/2024 |
0.64331 % | Candriam Luxembourg S.A. | 3,95,377 | 0 | 30/9/2024 |
0.45434 % | Loomis, Sayles & Company, L.P. | 2,79,237 | 0 | 31/8/2024 |
0.44158 % | Candriam Belgium S.A. | 2,71,398 | 2,71,398 | 30/6/2024 |
0.44137 % | Artisan Partners Limited Partnership | 2,71,267 | -154 | 30/6/2024 |
0.34947 % | Putnam Investment Management, L.L.C. | 2,14,785 | 10,143 | 30/6/2024 |
0.32920 % | Wellington Management Company, LLP | 2,02,326 | 8,803 | 30/6/2024 |
0.31141 % | Invesco Advisers, Inc. | 1,91,391 | 1,05,913 | 30/6/2024 |
0.30046 % | SilverArc Capital Management, LLC | 1,84,662 | 886 | 30/6/2024 |
0.28886 % | BlackRock Investment Management, LLC | 1,77,532 | 3,820 | 30/6/2024 |
0.28410 % | Meeker (David P) | 1,74,605 | -986 | 22/4/2024 |
0.28091 % | Samsara BioCapital, LLC | 1,72,647 | 0 | 30/6/2024 |
0.27544 % | Oppenheimer Asset Management Inc. | 1,69,288 | 1,69,288 | 30/6/2024 |
0.25430 % | BlackRock Advisors (UK) Limited | 1,56,292 | 332 | 30/9/2024 |
0.23837 % | Jane Street Capital, L.L.C. | 1,46,500 | 1,20,182 | 30/6/2024 |
0.23799 % | Nuveen LLC | 1,46,270 | 6,384 | 30/6/2024 |
0.23499 % | BlackRock Asset Management Ireland Limited | 1,44,426 | 79,800 | 30/6/2024 |
0.22208 % | UBS Asset Management (Americas), Inc. | 1,36,493 | -89 | 30/6/2024 |
0.21805 % | BNY Mellon Asset Management | 1,34,012 | 9,007 | 30/6/2024 |
0.19100 % | Ghost Tree Capital, LLC | 1,17,388 | -7,612 | 30/6/2024 |
0.18354 % | abrdn Inc. | 1,12,804 | 0 | 30/9/2024 |
0.17379 % | Marshall Wace LLP | 1,06,809 | 87,059 | 30/6/2024 |
0.17217 % | JGP Gest¿o de Recursos Ltda. | 1,05,814 | 1,00,126 | 31/3/2024 |
0.16943 % | Algert Global LLC | 1,04,132 | 35,084 | 30/6/2024 |
0.16894 % | AQR Capital Management, LLC | 1,03,830 | 32,831 | 30/6/2024 |
0.16692 % | Lord, Abbett & Co. LLC | 1,02,591 | -1,78,566 | 30/6/2024 |
0.16510 % | Samsung Asset Management Co., Ltd. | 1,01,469 | -4,859 | 30/9/2024 |
0.16427 % | Hennion & Walsh Asset Management, Inc. | 1,00,961 | 4,583 | 30/9/2024 |
0.15935 % | Smith (Hunter C) | 97,939 | 0 | 22/4/2024 |
0.15923 % | J.P. Morgan Securities plc | 97,865 | 82,413 | 30/6/2024 |
0.14808 % | First Trust Advisors L.P. | 91,010 | 91,010 | 30/6/2024 |
0.14432 % | Schweizerische Nationalbank | 88,700 | -4,600 | 30/6/2024 |
0.14336 % | ClearBridge Investments, LLC | 88,108 | -1,896 | 30/6/2024 |
0.14019 % | BofA Global Research (US) | 86,161 | -19,012 | 30/6/2024 |
0.13880 % | Invesco Capital Management LLC | 85,309 | 82,582 | 30/6/2024 |
0.13515 % | Rhumbline Advisers Ltd. Partnership | 83,063 | 6,339 | 30/6/2024 |
0.11806 % | Rafferty Asset Management LLC | 72,562 | -1,46,095 | 30/6/2024 |
0.10778 % | NISA Investment Advisors, L.L.C. | 66,240 | -3,08,107 | 30/9/2024 |
0.10729 % | UBS Financial Services, Inc. | 65,942 | -1,05,623 | 30/6/2024 |
0.10113 % | Northern Trust Global Investments | 62,156 | 11,335 | 30/6/2024 |
0.09937 % | AllianceBernstein L.P. | 61,070 | 7,640 | 30/6/2024 |
0.09854 % | Goldman Sachs Asset Management, L.P. | 60,561 | -46,218 | 30/6/2024 |
0.09338 % | UBS Asset Management (Switzerland) | 57,391 | 9,896 | 30/6/2024 |
0.08851 % | Mellon Investments Corporation | 54,397 | 15,068 | 30/6/2024 |
0.08726 % | Barclays Bank PLC | 53,631 | -73,905 | 30/6/2024 |
0.08709 % | Legal & General Investment Management Ltd. | 53,526 | 6,110 | 30/6/2024 |
0.08020 % | Manulife Investment Management (North America) Limited | 49,291 | 1,667 | 30/6/2024 |
0.07992 % | Nan Fung Life Sciences | 49,120 | 0 | 30/6/2024 |
0.07947 % | WEDGE Capital Management, L.L.P. | 48,844 | -14,353 | 30/9/2024 |
0.07319 % | Caption Management, LLC | 44,984 | 44,984 | 30/6/2024 |
0.07282 % | California State Teachers Retirement System | 44,757 | -3,137 | 30/6/2024 |
0.07199 % | Woodline Partners LP | 44,247 | -1,27,960 | 30/6/2024 |
0.07151 % | Ostrum Asset Management | 43,951 | 37,901 | 30/6/2024 |
0.07035 % | Norges Bank Investment Management (NBIM) | 43,238 | 43,238 | 30/6/2024 |
0.06731 % | Harbor Capital Advisors, Inc. | 41,368 | 6,741 | 30/9/2024 |
0.06576 % | Columbia Threadneedle Investments (US) | 40,415 | 19,435 | 30/6/2024 |
0.06540 % | MFS Investment Management | 40,192 | -115 | 31/8/2024 |
0.06415 % | State of Wisconsin Investment Board | 39,427 | 6,123 | 30/6/2024 |
0.06152 % | Voya Investment Management LLC | 37,811 | -1,31,900 | 30/6/2024 |
0.05939 % | Nomura Asset Management Co., Ltd. | 36,500 | 36,500 | 30/11/2023 |
0.05674 % | Mazabraud (Yann) | 34,870 | 10,375 | 22/4/2024 |
0.05412 % | T. Rowe Price International Ltd | 33,260 | 2,197 | 30/6/2024 |
0.05361 % | UBS Fund Management (Switzerland) AG | 32,946 | -10,218 | 30/6/2024 |
0.05241 % | Mirae Asset Global Investments (USA) LLC | 32,211 | 32,211 | 30/6/2024 |
0.05150 % | MetLife Investment Management, LLC | 31,652 | 4,529 | 30/6/2024 |
0.05044 % | TD Asset Management Inc. | 31,000 | 3,400 | 30/6/2024 |
0.04792 % | Corebridge Financial Inc | 29,454 | 29,454 | 30/6/2024 |
0.04741 % | Fulcrum Asset Management LLP | 29,140 | -279 | 31/7/2024 |