8.59336 % | The Vanguard Group, Inc. | 1,43,54,342 | -3,81,474 | 30/6/2024 |
8.17780 % | Wellington Management Company, LLP | 1,36,60,196 | -10,54,530 | 30/6/2024 |
6.52702 % | BlackRock Institutional Trust Company, N.A. | 1,09,02,738 | 7,79,058 | 30/6/2024 |
5.84153 % | Farallon Capital Management, L.L.C. | 97,57,692 | 22,49,820 | 30/6/2024 |
4.53130 % | Baker Bros. Advisors LP | 75,69,090 | 19,841 | 30/6/2024 |
3.76960 % | Nextech Invest, Ltd. | 62,96,740 | 0 | 30/6/2024 |
3.58071 % | BVF Partners L.P. | 59,81,212 | 0 | 30/6/2024 |
3.36748 % | Fidelity Management & Research Company LLC | 56,25,035 | 14,58,597 | 30/6/2024 |
3.17713 % | Alphabet, Inc. | 53,07,075 | 5,563 | 30/6/2024 |
3.14840 % | Paradigm BioCapital Advisors LP | 52,59,089 | 23,44,114 | 30/6/2024 |
3.03584 % | State Street Global Advisors (US) | 50,71,068 | -3,14,952 | 30/6/2024 |
3.03077 % | T. Rowe Price Associates, Inc. | 50,62,599 | 3,91,615 | 30/6/2024 |
3.01072 % | Bellevue Asset Management AG | 50,29,100 | -44,500 | 30/6/2024 |
2.77791 % | Janus Henderson Investors | 46,40,218 | 7,28,099 | 30/6/2024 |
2.63822 % | Casdin Capital, LLC | 44,06,875 | -12,10,724 | 30/6/2024 |
2.56194 % | Boxer Capital, L.L.C. | 42,79,464 | 0 | 30/6/2024 |
1.99692 % | Geode Capital Management, L.L.C. | 33,35,656 | 2,82,965 | 30/6/2024 |
1.97006 % | Woodline Partners LP | 32,90,791 | -5,06,357 | 30/6/2024 |
1.84990 % | Deerfield Management Company, L.P. | 30,90,073 | 0 | 30/6/2024 |
1.64543 % | Andreessen Horowitz | 27,48,523 | 0 | 30/6/2024 |
1.41498 % | Balyasny Asset Management LP | 23,63,584 | 7,08,689 | 30/6/2024 |
1.39520 % | Borisy (Alexis) | 23,30,542 | 4,248 | 20/6/2024 |
1.33159 % | JP Morgan Asset Management | 22,24,283 | -1,82,612 | 30/6/2024 |
1.31913 % | Holocene Advisors, LP | 22,03,474 | -2,18,937 | 30/6/2024 |
1.10671 % | Norges Bank Investment Management (NBIM) | 18,48,647 | 15,66,942 | 30/6/2024 |
0.99648 % | Lord, Abbett & Co. LLC | 16,64,516 | -13,315 | 31/8/2024 |
0.71839 % | Logos Global Management LLC | 12,00,000 | 12,00,000 | 30/6/2024 |
0.68419 % | BlackRock Financial Management, Inc. | 11,42,863 | 79,755 | 30/6/2024 |
0.66432 % | Charles Schwab Investment Management, Inc. | 11,09,684 | 57,421 | 30/6/2024 |
0.64180 % | Northern Trust Investments, Inc. | 10,72,055 | -37,405 | 30/6/2024 |
0.61960 % | Goldman Sachs & Company, Inc. | 10,34,972 | 3,34,291 | 30/6/2024 |
0.60810 % | Invus Public Equities Advisors, LLC | 10,15,776 | -3,02,873 | 30/6/2024 |
0.59714 % | Frazier Life Sciences Management, L.P. | 9,97,455 | 0 | 30/6/2024 |
0.56465 % | Rock Springs Capital Management LP | 9,43,195 | 19,514 | 30/6/2024 |
0.54718 % | Hood River Capital Management LLC | 9,14,003 | 9,14,003 | 30/6/2024 |
0.51256 % | Soleus Capital Management, L.P. | 8,56,178 | 1,27,478 | 30/6/2024 |
0.50856 % | Morgan Stanley & Co. LLC | 8,49,505 | 6,716 | 30/6/2024 |
0.48854 % | Marshall Wace LLP | 8,16,055 | -7,19,885 | 30/6/2024 |
0.45199 % | Avidity Partners Management LP | 7,55,000 | 1,20,000 | 30/6/2024 |
0.43670 % | Finepoint Capital LP | 7,29,464 | 52,364 | 30/6/2024 |
0.39665 % | Candriam Luxembourg S.A. | 6,62,564 | 0 | 30/9/2024 |
0.38962 % | Eventide Asset Management, LLC | 6,50,826 | 2,89,826 | 30/6/2024 |
0.38034 % | Columbia Threadneedle Investments (UK) | 6,35,319 | -2,45,391 | 30/6/2024 |
0.37222 % | JPMorgan Asset Management U.K. Limited | 6,21,752 | -2,18,680 | 30/6/2024 |
0.35657 % | Goldsmith Mark A | 5,95,609 | 0 | 11/10/2024 |
0.33186 % | Candriam Belgium S.A. | 5,54,334 | -29,616 | 30/6/2024 |
0.32483 % | Victory Capital Management Inc. | 5,42,601 | -57,980 | 30/6/2024 |
0.32339 % | Pzena Investment Management, LLC | 5,40,194 | -1,60,971 | 30/6/2024 |
0.31089 % | American Century Investment Management, Inc. | 5,19,305 | 5,19,305 | 30/6/2024 |
0.30645 % | Dafna Capital Management, LLC | 5,11,894 | 0 | 30/6/2024 |
0.30446 % | MIC Capital Management UK LLP | 5,08,569 | 0 | 30/6/2024 |
0.29746 % | Columbia Threadneedle Investments (US) | 4,96,878 | 49,167 | 30/6/2024 |
0.28908 % | BlackRock Advisors (UK) Limited | 4,82,883 | 617 | 30/9/2024 |
0.27245 % | Sofinnova Investments, Inc | 4,55,099 | 4,55,099 | 30/6/2024 |
0.27052 % | BlackRock Asset Management Ireland Limited | 4,51,870 | 1,15,991 | 30/6/2024 |
0.25154 % | BlackRock Investment Management, LLC | 4,20,169 | 59,350 | 30/6/2024 |
0.24532 % | Nuveen LLC | 4,09,781 | 45,858 | 30/6/2024 |
0.24476 % | Citadel Advisors LLC | 4,08,842 | -1,79,246 | 30/6/2024 |
0.23916 % | Goldman Sachs Asset Management, L.P. | 3,99,489 | -13,221 | 30/6/2024 |
0.23434 % | BlackRock Investment Management (UK) Ltd. | 3,91,439 | 44,624 | 30/6/2024 |
0.23383 % | Dimensional Fund Advisors, L.P. | 3,90,583 | -9,40,676 | 30/6/2024 |
0.22811 % | BofA Global Research (US) | 3,81,041 | -1,40,355 | 30/6/2024 |
0.22785 % | Jane Street Capital, L.L.C. | 3,80,594 | 2,51,127 | 30/6/2024 |
0.21696 % | BNY Mellon Asset Management | 3,62,416 | 46,589 | 30/6/2024 |
0.20246 % | Partners HealthCare System, Inc | 3,38,191 | 0 | 30/9/2024 |
0.19727 % | First Turn Management, LLC | 3,29,519 | 3,29,519 | 30/6/2024 |
0.19456 % | Integral Health Asset Management, LLC | 3,25,000 | -95,000 | 30/6/2024 |
0.19134 % | AllianceBernstein L.P. | 3,19,618 | -3,746 | 30/6/2024 |
0.18402 % | Columbia Wanger Asset Management, LLC | 3,07,387 | 0 | 30/6/2024 |
0.17325 % | MPM BioImpact LLC | 2,89,396 | 16,179 | 30/6/2024 |
0.16927 % | AHL Partners LLP | 2,82,746 | 2,53,449 | 30/6/2024 |
0.16643 % | Mubadala Investment Company PJSC | 2,78,000 | 0 | 30/6/2024 |
0.16134 % | Ensign Peak Advisors, Inc. | 2,69,504 | 2,29,721 | 30/6/2024 |
0.16102 % | Mellon Investments Corporation | 2,68,962 | 65,210 | 30/6/2024 |
0.15749 % | Voya Investment Management LLC | 2,63,079 | -20,554 | 30/6/2024 |
0.14978 % | TD Asset Management Inc. | 2,50,194 | -4,400 | 30/6/2024 |
0.14918 % | Qube Research & Technologies Ltd | 2,49,188 | 81,708 | 30/6/2024 |
0.14574 % | Bessemer Trust Company, N.A. (US) | 2,43,442 | 0 | 30/6/2024 |
0.13683 % | Rhumbline Advisers Ltd. Partnership | 2,28,567 | 19,257 | 30/6/2024 |
0.13680 % | Susquehanna Fundamental Investments, LLC | 2,28,513 | 22,000 | 30/6/2024 |
0.13645 % | Point72 Asset Management, L.P. | 2,27,922 | 2,27,922 | 30/6/2024 |
0.13611 % | HSBC Private Bank (Suisse) S.A. | 2,27,365 | 19,081 | 31/8/2024 |
0.13579 % | Schweizerische Nationalbank | 2,26,831 | 26,700 | 30/6/2024 |
0.13419 % | Walleye Capital LLC | 2,24,143 | 1,89,186 | 30/6/2024 |
0.13188 % | TwinBeech Capital LP | 2,20,289 | 2,20,289 | 30/6/2024 |
0.13037 % | UBS Financial Services, Inc. | 2,17,763 | -87,216 | 30/6/2024 |
0.12714 % | Manulife Investment Management (North America) Limited | 2,12,368 | 13,318 | 30/6/2024 |
0.11405 % | Raymond James & Associates, Inc. | 1,90,505 | 1,16,135 | 30/9/2024 |
0.11113 % | Rafferty Asset Management LLC | 1,85,637 | -98,715 | 30/6/2024 |
0.10177 % | Adage Capital Management, L.P. | 1,70,000 | -30,000 | 30/6/2024 |
0.09773 % | Readystate Asset Management LP | 1,63,241 | 95,941 | 30/6/2024 |
0.09479 % | Kelsey (Stephen Michael) | 1,58,345 | 0 | 14/10/2024 |
0.09467 % | Nicholas Investment Partners, L.P. | 1,58,132 | 1,42,044 | 30/6/2024 |
0.09223 % | T. Rowe Price International Ltd | 1,54,060 | 10,734 | 30/6/2024 |
0.08506 % | Neuberger Berman, LLC | 1,42,087 | -1,272 | 30/6/2024 |
0.08235 % | JPMorgan Private Bank (United States) | 1,37,559 | -1,373 | 30/6/2024 |
0.08065 % | Conestoga Capital Advisors, LLC | 1,34,721 | -1,296 | 31/3/2024 |
0.07962 % | Acuta Capital Partners, LLC | 1,33,000 | -10,777 | 30/6/2024 |
0.07899 % | J.P. Morgan Securities plc | 1,31,944 | 95,918 | 30/6/2024 |
0.07826 % | Legal & General Investment Management Ltd. | 1,30,725 | 24,596 | 30/6/2024 |