7.60022 % | Fidelity Management & Research Company LLC | 52,03,110 | 35,40,565 | 30/6/2024 |
6.09026 % | RTW Investments L.P. | 41,69,393 | 60,000 | 30/6/2024 |
4.67426 % | Commodore Capital LP | 32,00,000 | -11,60,000 | 30/6/2024 |
4.01607 % | Deerfield Management Company, L.P. | 27,49,401 | 1,00,000 | 30/6/2024 |
3.50394 % | Federated Hermes Global Investment Management Corp. | 23,98,800 | 1,50,000 | 30/6/2024 |
3.39497 % | Samlyn Capital, LLC | 23,24,195 | 2,47,605 | 30/6/2024 |
3.07649 % | Franklin Advisers, Inc. | 21,06,163 | 2,41,915 | 30/6/2024 |
2.95036 % | Paradigm BioCapital Advisors LP | 20,19,814 | 20,19,814 | 30/6/2024 |
2.77534 % | Boxer Capital, L.L.C. | 19,00,000 | 0 | 30/6/2024 |
2.42907 % | Wellington Management Company, LLP | 16,62,941 | 4,14,301 | 30/6/2024 |
2.29896 % | Holocene Advisors, LP | 15,73,866 | 6,34,290 | 30/6/2024 |
2.26411 % | Driehaus Capital Management, LLC | 15,50,009 | 3,23,518 | 30/6/2024 |
2.16928 % | Morgan Stanley & Co. LLC | 14,85,092 | 5,56,281 | 30/6/2024 |
2.11953 % | Two Sigma Investments, LP | 14,51,027 | 20,418 | 30/6/2024 |
2.02339 % | T. Rowe Price Associates, Inc. | 13,85,216 | 1,99,862 | 30/6/2024 |
1.97926 % | Avoro Capital Advisors LLC | 13,55,000 | 4,66,112 | 30/6/2024 |
1.86832 % | BVF Partners L.P. | 12,79,049 | 1,06,800 | 30/6/2024 |
1.85079 % | Polar Capital LLP | 12,67,052 | 12,67,052 | 30/6/2024 |
1.84519 % | VR Adviser, LLC | 12,63,214 | -5,27,000 | 30/6/2024 |
1.76265 % | Lynx1 Capital Advisors LLC | 12,06,707 | -3,02,300 | 30/6/2024 |
1.49258 % | Fidelity Institutional Asset Management | 10,21,822 | 10,21,822 | 30/6/2024 |
1.48555 % | Janus Henderson Investors | 10,17,007 | 4,74,427 | 30/6/2024 |
1.47250 % | Incyte Corp | 10,08,076 | -29,96,468 | 30/6/2024 |
1.46227 % | Rock Springs Capital Management LP | 10,01,073 | -1,45,487 | 30/6/2024 |
1.40048 % | Woodline Partners LP | 9,58,769 | 2,87,970 | 30/6/2024 |
1.39929 % | Marshall Wace LLP | 9,57,952 | 8,53,060 | 30/6/2024 |
1.24160 % | Logos Global Management LLC | 8,50,000 | 8,50,000 | 30/6/2024 |
1.23353 % | Pictet Asset Management Ltd. | 8,44,474 | 2,14,799 | 30/6/2024 |
1.22699 % | Cormorant Asset Management, LP | 8,40,000 | 1,25,000 | 30/6/2024 |
1.12474 % | Adage Capital Management, L.P. | 7,70,000 | 4,45,000 | 30/6/2024 |
1.11066 % | Invus Public Equities Advisors, LLC | 7,60,355 | 3,05,274 | 30/6/2024 |
1.08417 % | BlackRock Financial Management, Inc. | 7,42,225 | 3,033 | 30/6/2024 |
1.05270 % | T. Rowe Price Investment Management, Inc. | 7,20,676 | -8,339 | 30/6/2024 |
1.02249 % | Novo Holdings A/S | 7,00,000 | 25,000 | 30/9/2024 |
1.01957 % | Candriam Luxembourg S.A. | 6,97,997 | 0 | 30/9/2024 |
0.99039 % | AllianceBernstein L.P. | 6,78,021 | 5,94,761 | 30/6/2024 |
0.91094 % | SilverArc Capital Management, LLC | 6,23,628 | 57,341 | 30/6/2024 |
0.85455 % | Balyasny Asset Management LP | 5,85,024 | 5,85,024 | 30/6/2024 |
0.84716 % | Invesco Advisers, Inc. | 5,79,967 | 5,78,811 | 30/6/2024 |
0.76437 % | Great Point Partners, LLC | 5,23,288 | 3,00,000 | 30/6/2024 |
0.76152 % | D. E. Shaw & Co., L.P. | 5,21,339 | 2,47,813 | 30/6/2024 |
0.62583 % | BlackRock Institutional Trust Company, N.A. | 4,28,443 | 26,103 | 30/6/2024 |
0.59808 % | Dafna Capital Management, LLC | 4,09,445 | 30,450 | 30/6/2024 |
0.57796 % | Lord, Abbett & Co. LLC | 3,95,672 | 71,042 | 30/6/2024 |
0.54969 % | Soleus Capital Management, L.P. | 3,76,321 | 1,80,744 | 30/6/2024 |
0.54499 % | Frazier Life Sciences Management, L.P. | 3,73,100 | -3,73,379 | 30/6/2024 |
0.49009 % | Tri Locum Partners LP | 3,35,514 | 49,192 | 30/6/2024 |
0.48134 % | Medical Strategy GmbH | 3,29,522 | 18,321 | 30/6/2024 |
0.47021 % | First Turn Management, LLC | 3,21,906 | 3,21,906 | 30/6/2024 |
0.43821 % | Perceptive Advisors LLC | 3,00,000 | 3,00,000 | 30/6/2024 |
0.43821 % | Baker Bros. Advisors LP | 3,00,000 | 3,00,000 | 30/6/2024 |
0.42166 % | StemPoint Capital LP | 2,88,668 | 54,797 | 30/6/2024 |
0.38690 % | State Street Global Advisors (US) | 2,64,873 | 20,197 | 30/6/2024 |
0.35533 % | Millennium Management LLC | 2,43,257 | 92,987 | 30/6/2024 |
0.31382 % | Voloridge Investment Management, LLC | 2,14,838 | 1,49,137 | 30/6/2024 |
0.30514 % | Handelsbanken Kapitalf¿rvaltning AB | 2,08,900 | 34,200 | 30/9/2024 |
0.30267 % | Goldman Sachs & Company, Inc. | 2,07,209 | 1,02,495 | 30/6/2024 |
0.29666 % | BlackRock Advisors (UK) Limited | 2,03,092 | 675 | 30/9/2024 |
0.28104 % | BlackRock Asset Management Ireland Limited | 1,92,397 | -7,721 | 30/6/2024 |
0.26617 % | TimesSquare Capital Management, LLC | 1,82,220 | 1,74,216 | 30/6/2024 |
0.26563 % | Citadel Advisors LLC | 1,81,853 | -1,70,355 | 30/6/2024 |
0.26161 % | Decheng Capital LLC | 1,79,098 | 77,300 | 30/6/2024 |
0.25540 % | Ally Bridge Group NY LLC | 1,74,844 | -81,084 | 30/6/2024 |
0.24955 % | BNP Paribas Securities Corp. North America | 1,70,844 | 67,959 | 30/6/2024 |
0.24069 % | Saturn V Capital Management LP | 1,64,773 | -2,11,856 | 30/6/2024 |
0.22802 % | OrbiMed Advisors, LLC | 1,56,100 | 1,56,100 | 30/6/2024 |
0.22789 % | Liu (Hui) | 1,56,016 | 98,085 | 15/3/2024 |
0.22678 % | The Vanguard Group, Inc. | 1,55,257 | 8,232 | 30/6/2024 |
0.22354 % | State of Wisconsin Investment Board | 1,53,038 | 1,30,307 | 30/6/2024 |
0.22213 % | Lundberg (Sven Ante) | 1,52,071 | 0 | 15/3/2024 |
0.21634 % | Aquilo Capital Management, LLC | 1,48,109 | -1,07,000 | 30/6/2024 |
0.21565 % | Sphera Funds Management Ltd. | 1,47,633 | -1,700 | 30/6/2024 |
0.19475 % | Algert Global LLC | 1,33,323 | 35,549 | 30/6/2024 |
0.18632 % | TD Asset Management Inc. | 1,27,554 | -23,620 | 30/6/2024 |
0.18469 % | BlackRock Investment Management (UK) Ltd. | 1,26,442 | 40,537 | 30/6/2024 |
0.18259 % | Affinity Asset Advisors LLC | 1,25,000 | 1,25,000 | 30/6/2024 |
0.17752 % | Invesco Capital Management LLC | 1,21,529 | -5,564 | 30/6/2024 |
0.17534 % | Nan Fung Life Sciences | 1,20,038 | 30,522 | 30/6/2024 |
0.17049 % | HighVista Strategies LLC | 1,16,718 | -4,962 | 30/6/2024 |
0.16652 % | Ensign Peak Advisors, Inc. | 1,14,000 | 1,14,000 | 30/6/2024 |
0.16068 % | DWS Investment GmbH | 1,10,000 | 0 | 30/6/2024 |
0.14607 % | Integral Health Asset Management, LLC | 1,00,000 | -65,000 | 30/6/2024 |
0.14607 % | Tang Capital Management, LLC | 1,00,000 | 1,00,000 | 30/6/2024 |
0.13219 % | Rhenman & Partners Asset Management AB | 90,500 | 90,500 | 30/6/2024 |
0.13043 % | Wellington Management Singapore Pte. Ltd. | 89,295 | 89,295 | 31/3/2024 |
0.13043 % | Wellington Management Japan Pte Ltd | 89,295 | -61,818 | 30/6/2023 |
0.12740 % | abrdn Inc. | 87,215 | 87,215 | 30/9/2024 |
0.12708 % | Nomura Asset Management Co., Ltd. | 87,000 | 87,000 | 30/11/2023 |
0.12278 % | Voya Investment Management LLC | 84,055 | 54,205 | 30/6/2024 |
0.11813 % | BofA Global Research (US) | 80,873 | 25,690 | 30/6/2024 |
0.11759 % | Nicholas Investment Partners, L.P. | 80,503 | 62,818 | 30/6/2024 |
0.11431 % | Schweizerische Nationalbank | 78,254 | 4,200 | 30/6/2024 |
0.11291 % | First Trust Advisors L.P. | 77,296 | 26,233 | 30/6/2024 |
0.10888 % | Jane Street Capital, L.L.C. | 74,542 | 61,764 | 30/6/2024 |
0.10769 % | Platinum Asset Management | 73,722 | -25,768 | 30/6/2024 |
0.10747 % | Iwicki (Mark T.) | 73,576 | 73,576 | 15/3/2024 |
0.10594 % | Principal Global Investors (Equity) | 72,526 | 3,740 | 31/8/2024 |
0.10320 % | J.P. Morgan Securities LLC | 70,652 | -26,024 | 30/6/2024 |
0.09710 % | Eversept Partners, LP | 66,474 | -53,008 | 30/6/2024 |
0.09176 % | Fred Alger Management, LLC | 62,816 | 42,219 | 30/6/2024 |