15.28770 % | Fidelity Management & Research Company LLC | 1,06,78,612 | 48,951 | 30/6/2022 |
8.31230 % | The Vanguard Group, Inc. | 58,06,227 | 6,86,912 | 30/6/2022 |
7.43595 % | Vifor (International), Ltd | 51,94,085 | 0 | 13/9/2022 |
5.85740 % | BlackRock Institutional Trust Company, N.A. | 40,91,453 | 3,06,603 | 30/6/2022 |
5.79228 % | State Street Global Advisors (US) | 40,45,964 | 4,04,301 | 30/6/2022 |
3.42637 % | Schall (Thomas J) | 23,93,352 | 0 | 13/9/2022 |
3.39672 % | Pictet Asset Management Ltd. | 23,72,645 | 5,32,478 | 30/6/2022 |
3.01063 % | Wasatch Global Investors Inc | 21,02,953 | 10,27,231 | 30/6/2022 |
2.56640 % | Baker Bros. Advisors LP | 17,92,657 | 8,75,795 | 30/6/2022 |
2.20022 % | GW&K Investment Management, LLC | 15,36,877 | 3,75,530 | 30/6/2022 |
2.04006 % | Cormorant Asset Management, LP | 14,25,000 | 5,60,000 | 30/6/2022 |
2.01064 % | Invesco Advisers, Inc. | 14,04,451 | 34,143 | 30/6/2022 |
1.91375 % | Hood River Capital Management LLC | 13,36,776 | 13,36,776 | 30/6/2022 |
1.68780 % | Marshall Wace LLP | 11,78,948 | -2,19,635 | 30/6/2022 |
1.57453 % | Norges Bank Investment Management (NBIM) | 10,99,824 | 6,61,000 | 31/12/2021 |
1.57102 % | HealthCor Management, L.P. | 10,97,370 | 1,40,630 | 30/6/2022 |
1.44155 % | Geode Capital Management, L.L.C. | 10,06,934 | 6,519 | 30/6/2022 |
1.20670 % | Nuveen LLC | 8,42,891 | 3,40,858 | 30/6/2022 |
1.04277 % | Eventide Asset Management, LLC | 7,28,385 | 0 | 30/6/2022 |
0.94917 % | Morgan Stanley & Co. LLC | 6,63,007 | 2,62,249 | 30/6/2022 |
0.91145 % | Sofinnova Investments, Inc | 6,36,659 | 62,975 | 30/6/2022 |
0.85897 % | Logos Global Management LLC | 6,00,000 | 6,00,000 | 30/6/2022 |
0.83184 % | Wellington Management Company, LLP | 5,81,050 | -64,783 | 30/6/2022 |
0.82179 % | Integral Health Asset Management, LLC | 5,74,029 | 1,74,029 | 30/6/2022 |
0.79355 % | Principal Global Investors (Equity) | 5,54,300 | 2,49,434 | 30/6/2022 |
0.78175 % | Barclays Bank PLC | 5,46,057 | 5,05,367 | 30/6/2022 |
0.78099 % | Tri Locum Partners LP | 5,45,532 | 2,49,205 | 30/6/2022 |
0.70514 % | Northern Trust Investments, Inc. | 4,92,544 | 46,115 | 30/6/2022 |
0.69505 % | APG Asset Management N.V. | 4,85,501 | 4,85,501 | 31/3/2022 |
0.63232 % | Perceptive Advisors LLC | 4,41,680 | -12,13,399 | 30/6/2022 |
0.54723 % | Charles Schwab Investment Management, Inc. | 3,82,244 | 14,545 | 30/6/2022 |
0.53069 % | Millennium Management LLC | 3,70,692 | -9,30,257 | 30/6/2022 |
0.51866 % | Voloridge Investment Management, LLC | 3,62,291 | -3,01,944 | 30/6/2022 |
0.45346 % | Invesco Capital Management LLC | 3,16,743 | 76,060 | 30/6/2022 |
0.44846 % | Goldman Sachs & Company, Inc. | 3,13,253 | 62,366 | 30/6/2022 |
0.44399 % | T. Rowe Price Associates, Inc. | 3,10,129 | -55,505 | 30/6/2022 |
0.43582 % | Citadel Advisors LLC | 3,04,424 | -1,906 | 30/6/2022 |
0.40604 % | Raymond James & Associates, Inc. | 2,83,620 | -11,213 | 30/6/2022 |
0.37153 % | Raymond James Financial Services Advisors, Inc. | 2,59,519 | 12,347 | 30/6/2022 |
0.33152 % | PGIM Quantitative Solutions LLC | 2,31,570 | 2,31,570 | 30/6/2022 |
0.32847 % | Parametric Portfolio Associates LLC | 2,29,439 | -14,171 | 30/6/2022 |
0.32073 % | Kanaya (Susan M) | 2,24,034 | 0 | 13/9/2022 |
0.31592 % | Thornburg Investment Management, Inc. | 2,20,675 | -25,602 | 30/6/2022 |
0.27986 % | Dimensional Fund Advisors, L.P. | 1,95,488 | -1,24,852 | 30/6/2022 |
0.26477 % | Lisanti Capital Growth, LLC | 1,84,946 | -1,36,623 | 30/6/2022 |
0.25810 % | Lord, Abbett & Co. LLC | 1,80,285 | 1,69,409 | 30/6/2022 |
0.25803 % | BNY Mellon Asset Management | 1,80,238 | 21,793 | 30/6/2022 |
0.25394 % | BlackRock Investment Management, LLC | 1,77,382 | 7,809 | 30/6/2022 |
0.24105 % | BlackRock Financial Management, Inc. | 1,68,375 | 22,142 | 30/6/2022 |
0.24086 % | Granahan Investment Management, Inc. | 1,68,245 | 45,478 | 30/6/2022 |
0.24071 % | Two Sigma Investments, LP | 1,68,141 | -8,33,794 | 30/6/2022 |
0.23595 % | Goldman Sachs Asset Management, L.P. | 1,64,816 | 39,130 | 30/6/2022 |
0.22906 % | Altium Capital Management LP | 1,60,000 | 1,60,000 | 30/6/2022 |
0.22824 % | Citi Investment Research (US) | 1,59,427 | 1,17,029 | 30/6/2022 |
0.22104 % | Soleus Capital Management, L.P. | 1,54,400 | 1,54,400 | 30/6/2022 |
0.22069 % | Susquehanna International Group, LLP | 1,54,151 | -18,198 | 30/6/2022 |
0.21813 % | Rafferty Asset Management LLC | 1,52,368 | -73,036 | 30/6/2022 |
0.21206 % | Feczko (Joseph M) | 1,48,127 | 0 | 13/9/2022 |
0.20516 % | Edwards (Thomas A) | 1,43,306 | 0 | 13/9/2022 |
0.20438 % | Parker (Geoffrey M) | 1,42,763 | 0 | 13/9/2022 |
0.19931 % | Assenagon Asset Management S.A. | 1,39,219 | -22,556 | 30/6/2022 |
0.19590 % | Northern Trust Global Investments | 1,36,838 | 38,823 | 30/6/2022 |
0.19570 % | Nomura Asset Management Co., Ltd. | 1,36,700 | -59,499 | 30/11/2021 |
0.19361 % | BofA Global Research (US) | 1,35,237 | -1,11,166 | 30/6/2022 |
0.19327 % | BZ Bank AG (Asset Management) | 1,35,000 | 0 | 31/5/2022 |
0.18897 % | Schweizerische Nationalbank | 1,32,000 | 16,100 | 30/6/2022 |
0.17623 % | Medical Strategy GmbH | 1,23,100 | 7,500 | 31/5/2022 |
0.17337 % | International Biotechnology Trust PLC | 1,21,100 | 85,000 | 30/6/2022 |
0.17000 % | Allspring Global Investments, LLC | 1,18,744 | 39,199 | 30/6/2022 |
0.16298 % | Capital Fund Management S.A. | 1,13,844 | 1,13,844 | 30/6/2022 |
0.15050 % | ExodusPoint Capital Management, LP | 1,05,124 | 11,155 | 30/6/2022 |
0.13850 % | Ensign Peak Advisors, Inc. | 96,746 | 23,783 | 30/6/2022 |
0.13522 % | Mutual of America Capital Management LLC | 94,450 | -41,248 | 30/6/2022 |
0.13505 % | UBS Financial Services, Inc. | 94,337 | -73,833 | 30/6/2022 |
0.12737 % | Aperio Group, LLC | 88,969 | -6,250 | 30/6/2022 |
0.12549 % | Cappel (Markus J) | 87,658 | 0 | 13/9/2022 |
0.12277 % | BlackRock Advisors (UK) Limited | 85,759 | 5,091 | 31/8/2022 |
0.12262 % | Mirabella Financial Services LLP | 85,653 | 85,653 | 30/6/2022 |
0.11811 % | Rhumbline Advisers Ltd. Partnership | 82,501 | 8,950 | 30/6/2022 |
0.11544 % | Group One Trading, L.P. | 80,635 | 80,635 | 30/6/2022 |
0.11195 % | Tekla Capital Management LLC | 78,197 | 0 | 30/6/2022 |
0.10809 % | AllianceBernstein L.P. | 75,500 | 13,100 | 30/6/2022 |
0.10705 % | California State Teachers Retirement System | 74,776 | 9,871 | 30/6/2022 |
0.10652 % | BlackRock Asset Management Ireland Limited | 74,403 | 9,221 | 30/6/2022 |
0.10436 % | Jane Street Capital, L.L.C. | 72,896 | -41,935 | 30/6/2022 |
0.10415 % | McKinnell (Henry A Jr) | 72,749 | 7,726 | 20/5/2022 |
0.10340 % | Allianz Global Investors U.S. LLC | 72,225 | 7,540 | 30/6/2022 |
0.09947 % | Jump Financial, LLC | 69,484 | 60,484 | 30/6/2022 |
0.09786 % | Cahill Wealth Management, LLC | 68,358 | 23,445 | 30/6/2022 |
0.09306 % | Hudson Bay Capital Management LP | 65,000 | 10,000 | 30/6/2022 |
0.09105 % | Cubist Systematic Strategies, LLC | 63,599 | 31,059 | 30/6/2022 |
0.09047 % | EFG Asset Management (UK) Limited | 63,195 | 11,721 | 31/5/2022 |
0.08883 % | EFG Asset Management (North America) Corp | 62,051 | 8,550 | 30/6/2022 |
0.08757 % | Ohio Public Employees Retirement System | 61,171 | 26,172 | 30/6/2022 |
0.08715 % | Algert Global LLC | 60,875 | 46,740 | 30/6/2022 |
0.08332 % | Jennison Associates LLC | 58,200 | 58,200 | 30/6/2022 |
0.07855 % | State of Wisconsin Investment Board | 54,866 | -11,834 | 30/6/2022 |
0.07526 % | SEI Investments Management Corporation | 52,572 | 52,572 | 30/6/2022 |
0.07434 % | PanAgora Asset Management Inc. | 51,929 | 23,495 | 30/6/2022 |
0.07300 % | Legal & General Investment Management Ltd. | 50,994 | 8,111 | 30/6/2022 |